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Items: 40

1.

Modelling the transport and decay processes of microbial tracers in a macro-tidal estuary.

Abu-Bakar A, Ahmadian R, Falconer RA.

Water Res. 2017 Oct 15;123:802-824. doi: 10.1016/j.watres.2017.07.007. Epub 2017 Jul 3.

PMID:
28750330
2.

A Novel Theranostic Strategy for MMP-14-Expressing Glioblastomas Impacts Survival.

Mohanty S, Chen Z, Li K, Morais GR, Klockow J, Yerneni K, Pisani L, Chin FT, Mitra S, Cheshier S, Chang E, Gambhir SS, Rao J, Loadman PM, Falconer RA, Daldrup-Link HE.

Mol Cancer Ther. 2017 Sep;16(9):1909-1921. doi: 10.1158/1535-7163.MCT-17-0022. Epub 2017 Jun 28.

PMID:
28659432
3.

Exploring and Exploiting Acceptor Preferences of the Human Polysialyltransferases as a Basis for an Inhibitor Screen.

Ehrit J, Keys TG, Sutherland M, Wolf S, Meier C, Falconer RA, Gerardy-Schahn R.

Chembiochem. 2017 Jul 4;18(13):1332-1337. doi: 10.1002/cbic.201700157. Epub 2017 May 24.

PMID:
28472541
4.

Rationalized Computer-Aided Design of Matrix-Metalloprotease-Selective Prodrugs.

Jain M, Harburn JJ, Gill JH, Loadman PM, Falconer RA, Mooney CA, Cobb SL, Berry DJ.

J Med Chem. 2017 May 25;60(10):4496-4502. doi: 10.1021/acs.jmedchem.6b01472. Epub 2017 May 10.

PMID:
28471664
5.

Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment.

Elkashef SM, Allison SJ, Sadiq M, Basheer HA, Ribeiro Morais G, Loadman PM, Pors K, Falconer RA.

Sci Rep. 2016 Sep 9;6:33026. doi: 10.1038/srep33026.

6.

Presurgical Rehearsals for Patients Considering "Awake" Deep Brain Stimulation.

Falconer RA, Rogers SL, Brewer CM, Piscitani F, Shenai MB.

Front Surg. 2016 Aug 2;3:44. doi: 10.3389/fsurg.2016.00044. eCollection 2016.

7.

An optimised assay for quantitative, high-throughput analysis of polysialyltransferase activity.

Elkashef SM, Sutherland M, Patterson LH, Loadman PM, Falconer RA.

Analyst. 2016 Oct 21;141(20):5849-5856. Epub 2016 Aug 12.

PMID:
27517096
8.

The use of thermographic imaging to evaluate therapeutic response in human tumour xenograft models.

Hussain N, Connah D, Ugail H, Cooper PA, Falconer RA, Patterson LH, Shnyder SD.

Sci Rep. 2016 Aug 5;6:31136. doi: 10.1038/srep31136.

9.

Nilotinib Effects in Parkinson's disease and Dementia with Lewy bodies.

Pagan F, Hebron M, Valadez EH, Torres-Yaghi Y, Huang X, Mills RR, Wilmarth BM, Howard H, Dunn C, Carlson A, Lawler A, Rogers SL, Falconer RA, Ahn J, Li Z, Moussa C.

J Parkinsons Dis. 2016 Jul 11;6(3):503-17. doi: 10.3233/JPD-160867.

10.

The Effect of Polysialic Acid Expression on Glioma Cell Nano-mechanics.

Grant CA, Twigg PC, Saeed RF, Lawson G, Falconer RA, Shnyder SD.

Bionanoscience. 2016;6:81-84. Epub 2016 Jan 25.

11.

Novel strategies for the synthesis of unsymmetrical glycosyl disulfides.

Morais GR, Springett BR, Pauze M, Schröder L, Northrop M, Falconer RA.

Org Biomol Chem. 2016 Mar 7;14(9):2749-54. doi: 10.1039/c6ob00230g.

PMID:
26853381
12.

Modelling the fate and transport of faecal bacteria in estuarine and coastal waters.

Gao G, Falconer RA, Lin B.

Mar Pollut Bull. 2015 Nov 15;100(1):162-8. doi: 10.1016/j.marpolbul.2015.09.011. Epub 2015 Sep 16.

13.

Predicting the disinfection efficiency range in chlorine contact tanks through a CFD-based approach.

Angeloudis A, Stoesser T, Falconer RA.

Water Res. 2014 Sep 1;60:118-29. doi: 10.1016/j.watres.2014.04.037. Epub 2014 May 2.

PMID:
24835958
14.

Tumor-targeted prodrug ICT2588 demonstrates therapeutic activity against solid tumors and reduced potential for cardiovascular toxicity.

Gill JH, Loadman PM, Shnyder SD, Cooper P, Atkinson JM, Ribeiro Morais G, Patterson LH, Falconer RA.

Mol Pharm. 2014 Apr 7;11(4):1294-300. doi: 10.1021/mp400760b. Epub 2014 Mar 27.

PMID:
24641451
15.

Development of novel tumor-targeted theranostic nanoparticles activated by membrane-type matrix metalloproteinases for combined cancer magnetic resonance imaging and therapy.

Ansari C, Tikhomirov GA, Hong SH, Falconer RA, Loadman PM, Gill JH, Castaneda R, Hazard FK, Tong L, Lenkov OD, Felsher DW, Rao J, Daldrup-Link HE.

Small. 2014 Feb 12;10(3):566-75, 417. doi: 10.1002/smll.201301456. Epub 2013 Aug 27.

16.

Pharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migration.

Al-Saraireh YM, Sutherland M, Springett BR, Freiberger F, Ribeiro Morais G, Loadman PM, Errington RJ, Smith PJ, Fukuda M, Gerardy-Schahn R, Patterson LH, Shnyder SD, Falconer RA.

PLoS One. 2013 Aug 9;8(8):e73366. doi: 10.1371/journal.pone.0073366. eCollection 2013.

17.

Micro-community cytometry: sensing changes in cell health and glycoconjugate expression by imaging and flow cytometry.

Smith PJ, Falconer RA, Errington RJ.

J Microsc. 2013 Aug;251(2):113-22. doi: 10.1111/jmi.12060. Epub 2013 Jun 13. Review.

18.

NCAM polysialylation during adherence transitions: live cell monitoring using an antibody-mimetic EGFP-endosialidase and the viability dye DRAQ7.

Smith PJ, Furon E, Wiltshire M, Chappell S, Patterson LH, Shnyder SD, Falconer RA, Errington RJ.

Cytometry A. 2013 Jul;83(7):659-71. doi: 10.1002/cyto.a.22306. Epub 2013 May 28.

19.

Modelling importance of sediment effects on fate and transport of enterococci in the Severn Estuary, UK.

Gao G, Falconer RA, Lin B.

Mar Pollut Bull. 2013 Feb 15;67(1-2):45-54. doi: 10.1016/j.marpolbul.2012.12.002. Epub 2013 Jan 3.

PMID:
23290609
20.

Synthesis and biological evaluation of colchicine C-ring analogues tethered with aliphatic linkers suitable for prodrug derivatisation.

Fournier-Dit-Chabert J, Vinader V, Santos AR, Redondo-Horcajo M, Dreneau A, Basak R, Cosentino L, Marston G, Abdel-Rahman H, Loadman PM, Shnyder SD, Díaz JF, Barasoain I, Falconer RA, Pors K.

Bioorg Med Chem Lett. 2012 Dec 15;22(24):7693-6. doi: 10.1016/j.bmcl.2012.09.104. Epub 2012 Oct 10.

PMID:
23103097
21.

Appraisal of chlorine contact tank modelling practices.

Rauen WB, Angeloudis A, Falconer RA.

Water Res. 2012 Nov 15;46(18):5834-47. doi: 10.1016/j.watres.2012.08.013. Epub 2012 Aug 23. Review.

PMID:
22963866
22.

Polysialyltransferase: a new target in metastatic cancer.

Falconer RA, Errington RJ, Shnyder SD, Smith PJ, Patterson LH.

Curr Cancer Drug Targets. 2012 Oct;12(8):925-39. Review.

PMID:
22463390
23.

Numerical modelling of sediment-bacteria interaction processes in surface waters.

Gao G, Falconer RA, Lin B.

Water Res. 2011 Feb;45(5):1951-60. doi: 10.1016/j.watres.2010.12.030. Epub 2011 Jan 8.

PMID:
21256533
24.

Development of a novel tumor-targeted vascular disrupting agent activated by membrane-type matrix metalloproteinases.

Atkinson JM, Falconer RA, Edwards DR, Pennington CJ, Siller CS, Shnyder SD, Bibby MC, Patterson LH, Loadman PM, Gill JH.

Cancer Res. 2010 Sep 1;70(17):6902-12. doi: 10.1158/0008-5472.CAN-10-1440. Epub 2010 Jul 27.

25.

A modelling assessment of contaminant distributions in the Severn Estuary.

Murdoch N, Jonas PJ, Falconer RA, Lin B.

Mar Pollut Bull. 2010;61(1-3):124-31. doi: 10.1016/j.marpolbul.2009.12.019. Epub 2010 Jan 15.

PMID:
20079502
26.

Identification of an acetyl disulfide derivative in the synthesis of thiosialosides.

Morais GR, Oliveira IF, Humphrey AJ, Falconer RA.

Carbohydr Res. 2010 Jan 11;345(1):160-2. doi: 10.1016/j.carres.2009.10.017. Epub 2009 Oct 22.

PMID:
19900671
27.

The changing landscape of cancer drug discovery: a challenge to the medicinal chemist of tomorrow.

Pors K, Goldberg FW, Leamon CP, Rigby AC, Snyder SA, Falconer RA.

Drug Discov Today. 2009 Nov;14(21-22):1045-50. doi: 10.1016/j.drudis.2009.07.004. Epub 2009 Jul 26. Review.

PMID:
19638319
28.

A facile preparation of trehalose analogues: 1,1-thiodisaccharides.

Morais GR, Humphrey AJ, Falconer RA.

Carbohydr Res. 2009 May 26;344(8):1039-45. doi: 10.1016/j.carres.2009.03.017. Epub 2009 Mar 21.

PMID:
19368901
29.

Guaianolide sesquiterpenes from Pulicaria crispa (Forssk.) Oliv.

Stavri M, Mathew KT, Gordon A, Shnyder SD, Falconer RA, Gibbons S.

Phytochemistry. 2008 Jun;69(9):1915-8. doi: 10.1016/j.phytochem.2008.03.012. Epub 2008 Apr 28.

PMID:
18448140
30.

Optimized LC-MS/MS quantification method for the detection of piperacillin and application to the development of charged liposaccharides as oral penetration enhancers.

Violette A, Cortes DA, Bergeon JA, Falconer RA, Toth I.

Int J Pharm. 2008 Mar 3;351(1-2):152-7. Epub 2007 Oct 6.

PMID:
18022334
31.

Design, synthesis and biological evaluation of novel lipoamino acid-based glycolipids for oral drug delivery.

Falconer RA, Toth I.

Bioorg Med Chem. 2007 Nov 15;15(22):7012-20. Epub 2007 Aug 22.

PMID:
17851079
32.

Measuring bed shear stress along vegetated river beds using FST-hemispheres.

Bockelmann-Evans BN, Davies R, Falconer RA.

J Environ Manage. 2008 Sep;88(4):627-37. Epub 2007 Jun 7.

PMID:
17560013
33.

Modelling the fate of faecal indicators in a coastal basin.

Kashefipour SM, Lin B, Falconer RA.

Water Res. 2006 Apr;40(7):1413-25. Epub 2006 Mar 14.

PMID:
16537086
34.

Decay of intestinal enterococci concentrations in high-energy estuarine and coastal waters: towards real-time T90 values for modelling faecal indicators in recreational waters.

Kay D, Stapleton CM, Wyer MD, McDonald AT, Crowther J, Paul N, Jones K, Francis C, Watkins J, Wilkinson J, Humphrey N, Lin B, Yang L, Falconer RA, Gardner S.

Water Res. 2005 Feb;39(4):655-67. Epub 2004 Dec 24.

PMID:
15707639
35.

Modelling hydroenvironmental and health risk assessment parameters along the South Wales Coast.

Harris EL, Falconer RA, Lin B.

J Environ Manage. 2004 Oct;73(1):61-70.

PMID:
15327847
36.

Predicting near-shore coliform bacteria concentrations using ANNS.

Lin B, Kashefipour SM, Falconer RA.

Water Sci Technol. 2003;48(10):225-32.

PMID:
15137174
37.

Flow and transport simulation models for prediction of chlorine contact tank flow-through curves.

Wang H, Shao X, Falconer RA.

Water Environ Res. 2003 Sep-Oct;75(5):455-71.

PMID:
14587956
38.

Hydro-environmental modelling for bathing water compliance of an estuarine basin.

Kashefipour SM, Lin B, Harris E, Falconer RA.

Water Res. 2002 Apr;36(7):1854-68.

PMID:
12044085
39.

Longitudinal dispersion coefficients in natural channels.

Kashefipour SM, Falconer RA.

Water Res. 2002 Mar;36(6):1596-608.

PMID:
11996348
40.

Synthesis of C-terminal glycopeptides from resin-bound glycosyl azides via a modified Staudinger reaction.

Malkinson JP, Falconer RA, Toth I.

J Org Chem. 2000 Aug 25;65(17):5249-52.

PMID:
10993353

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