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Items: 34


Cutaneous Barriers and Skin Immunity: Differentiating A Connected Network.

Eyerich S, Eyerich K, Traidl-Hoffmann C, Biedermann T.

Trends Immunol. 2018 Mar 15. pii: S1471-4906(18)30028-0. doi: 10.1016/ [Epub ahead of print] Review.


Type I immune response induces keratinocyte necroptosis and is associated with interface dermatitis.

Lauffer F, Jargosch M, Krause L, Garzorz-Stark N, Franz R, Roenneberg S, Böhner A, Mueller NS, Theis FJ, Schmidt-Weber CB, Biedermann T, Eyerich S, Eyerich K.

J Invest Dermatol. 2018 Mar 8. pii: S0022-202X(18)30215-X. doi: 10.1016/j.jid.2018.02.034. [Epub ahead of print]


Immune response patterns in non-communicable inflammatory skin diseases.

Eyerich K, Eyerich S.

J Eur Acad Dermatol Venereol. 2017 Nov 8. doi: 10.1111/jdv.14673. [Epub ahead of print] Review.


STAT1 Gain-of-Function and Dominant Negative STAT3 Mutations Impair IL-17 and IL-22 Immunity Associated with CMC.

Hiller J, Hagl B, Effner R, Puel A, Schaller M, Mascher B, Eyerich S, Eyerich K, Jansson AF, Ring J, Casanova JL, Renner ED, Traidl-Hoffmann C.

J Invest Dermatol. 2018 Mar;138(3):711-714. doi: 10.1016/j.jid.2017.09.035. Epub 2017 Oct 18. No abstract available.


Toll-like receptor 7/8 agonists stimulate plasmacytoid dendritic cells to initiate TH17-deviated acute contact dermatitis in human subjects.

Garzorz-Stark N, Lauffer F, Krause L, Thomas J, Atenhan A, Franz R, Roenneberg S, Boehner A, Jargosch M, Batra R, Mueller NS, Haak S, Groß C, Groß O, Traidl-Hoffmann C, Theis FJ, Schmidt-Weber CB, Biedermann T, Eyerich S, Eyerich K.

J Allergy Clin Immunol. 2017 Sep 19. pii: S0091-6749(17)31442-2. doi: 10.1016/j.jaci.2017.07.045. [Epub ahead of print]


Sebocytes contribute to skin inflammation by promoting the differentiation of T helper 17 cells.

Mattii M, Lovászi M, Garzorz N, Atenhan A, Quaranta M, Lauffer F, Konstantinow A, Küpper M, Zouboulis CC, Kemeny L, Eyerich K, Schmidt-Weber CB, Törőcsik D, Eyerich S.

Br J Dermatol. 2017 Aug 11. doi: 10.1111/bjd.15879. [Epub ahead of print]


Sebum lipids influence macrophage polarization and activation.

Lovászi M, Mattii M, Eyerich K, Gácsi A, Csányi E, Kovács D, Rühl R, Szegedi A, Kemény L, Ståhle M, Zouboulis CC, Eyerich S, Törőcsik D.

Br J Dermatol. 2017 Dec;177(6):1671-1682. doi: 10.1111/bjd.15754. Epub 2017 Nov 28.



Krause L, Mueller NS, Eyerich S.

J Allergy Clin Immunol. 2017 Mar;139(3):1065-1066. doi: 10.1016/j.jaci.2016.08.024. Epub 2016 Oct 26. No abstract available. Erratum in: J Allergy Clin Immunol. 2017 Mar;139(3):1068-1069.


Cytochrome P450s in human immune cells regulate IL-22 and c-Kit via an AHR feedback loop.

Effner R, Hiller J, Eyerich S, Traidl-Hoffmann C, Brockow K, Triggiani M, Behrendt H, Schmidt-Weber CB, Buters JT.

Sci Rep. 2017 Mar 9;7:44005. doi: 10.1038/srep44005.


Alpha-gal is a possible target of IgE-mediated reactivity to antivenom.

Fischer J, Eberlein B, Hilger C, Eyer F, Eyerich S, Ollert M, Biedermann T.

Allergy. 2017 May;72(5):764-771. doi: 10.1111/all.13073. Epub 2016 Nov 21.


A computational model to predict severity of atopic eczema from 30 serum proteins.

Krause L, Mourantchanian V, Brockow K, Theis FJ, Schmidt-Weber CB, Knapp B, Mueller NS, Eyerich S.

J Allergy Clin Immunol. 2016 Oct;138(4):1207-1210.e2. doi: 10.1016/j.jaci.2016.04.018. Epub 2016 May 13. No abstract available. Erratum in: J Allergy Clin Immunol. 2017 Mar;139(3):1068-1069.


A novel molecular disease classifier for psoriasis and eczema.

Garzorz-Stark N, Krause L, Lauffer F, Atenhan A, Thomas J, Stark SP, Franz R, Weidinger S, Balato A, Mueller NS, Theis FJ, Ring J, Schmidt-Weber CB, Biedermann T, Eyerich S, Eyerich K.

Exp Dermatol. 2016 Oct;25(10):767-74. doi: 10.1111/exd.13077.


Newly acquired kiwi fruit allergy after bone marrow transplantation from a kiwi-allergic donor.

Garzorz N, Thomas J, Eberlein B, Haferlach C, Ring J, Biedermann T, Schmidt-Weber C, Eyerich K, Seifert F, Eyerich S.

J Eur Acad Dermatol Venereol. 2016 Jul;30(7):1136-9. doi: 10.1111/jdv.13617. Epub 2016 Mar 16.


The Multi-Modal Immune Pathogenesis of Atopic Eczema.

Eyerich K, Eyerich S, Biedermann T.

Trends Immunol. 2015 Dec;36(12):788-801. doi: 10.1016/ Epub 2015 Nov 18. Review.


Dissecting susceptibility from exogenous triggers: the model of alopecia areata and associated inflammatory skin diseases.

Garzorz N, Alsisi M, Todorova A, Atenhan A, Thomas J, Lauffer F, Ring J, Schmidt-Weber C, Biedermann T, Eyerich S, Eyerich K.

J Eur Acad Dermatol Venereol. 2015 Dec;29(12):2429-35. doi: 10.1111/jdv.13325. Epub 2015 Sep 28.


Interleukin-22 Promotes Wound Repair in Diabetes by Improving Keratinocyte Pro-Healing Functions.

Avitabile S, Odorisio T, Madonna S, Eyerich S, Guerra L, Eyerich K, Zambruno G, Cavani A, Cianfarani F.

J Invest Dermatol. 2015 Nov;135(11):2862-2870. doi: 10.1038/jid.2015.278. Epub 2015 Jul 13.


Th22 cells in allergic disease.

Eyerich K, Eyerich S.

Allergo J Int. 2015;24(1):1-7. Epub 2015 Feb 9. Review.


Optimizing of the basophil activation test: Comparison of different basophil identification markers.

Eberlein B, Hann R, Eyerich S, Pennino D, Ring J, Schmidt-Weber CB, Buters J.

Cytometry B Clin Cytom. 2015 May-Jun;88(3):183-9. doi: 10.1002/cyto.b.21203. Epub 2014 Nov 17.


Optimizing of the basophil activation test: Comparison of different basophil identification markers.

Eberlein B, Hann R, Eyerich S, Pennino D, Ring J, Schmidt-Weber CB, Buters J.

Cytometry B Clin Cytom. 2014 Nov 8. doi: 10.1002/cytob.21203. [Epub ahead of print]


Defining Th-cell subsets in a classical and tissue-specific manner: Examples from the skin.

Eyerich S, Zielinski CE.

Eur J Immunol. 2014 Dec;44(12):3475-83. doi: 10.1002/eji.201444891. Epub 2014 Nov 2. Review.


Pyoderma gangrenosum, acne, psoriasis, arthritis and suppurative hidradenitis (PAPASH)-syndrome: a new entity within the spectrum of autoinflammatory syndromes?

Garzorz N, Papanagiotou V, Atenhan A, Andres C, Eyerich S, Eyerich K, Ring J, Brockow K.

J Eur Acad Dermatol Venereol. 2016 Jan;30(1):141-3. doi: 10.1111/jdv.12631. Epub 2014 Jul 28. No abstract available.


Allergic contact dermatitis in psoriasis patients: typical, delayed, and non-interacting.

Quaranta M, Eyerich S, Knapp B, Nasorri F, Scarponi C, Mattii M, Garzorz N, Harlfinger AT, Jaeger T, Grosber M, Pennino D, Mempel M, Schnopp C, Theis FJ, Albanesi C, Cavani A, Schmidt-Weber CB, Ring J, Eyerich K.

PLoS One. 2014 Jul 24;9(7):e101814. doi: 10.1371/journal.pone.0101814. eCollection 2014.


Intraindividual genome expression analysis reveals a specific molecular signature of psoriasis and eczema.

Quaranta M, Knapp B, Garzorz N, Mattii M, Pullabhatla V, Pennino D, Andres C, Traidl-Hoffmann C, Cavani A, Theis FJ, Ring J, Schmidt-Weber CB, Eyerich S, Eyerich K.

Sci Transl Med. 2014 Jul 9;6(244):244ra90. doi: 10.1126/scitranslmed.3008946.


Mixed T helper cell signatures in chronic rhinosinusitis with and without polyps.

Derycke L, Eyerich S, Van Crombruggen K, Pérez-Novo C, Holtappels G, Deruyck N, Gevaert P, Bachert C.

PLoS One. 2014 Jun 9;9(6):e97581. doi: 10.1371/journal.pone.0097581. eCollection 2014.


A common atopy-associated variant in the Th2 cytokine locus control region impacts transcriptional regulation and alters SMAD3 and SP1 binding.

Kretschmer A, Möller G, Lee H, Laumen H, von Toerne C, Schramm K, Prokisch H, Eyerich S, Wahl S, Baurecht H, Franke A, Claussnitzer M, Eyerich K, Teumer A, Milani L, Klopp N, Hauck SM, Illig T, Peters A, Waldenberger M, Adamski J, Reischl E, Weidinger S.

Allergy. 2014 May;69(5):632-42. doi: 10.1111/all.12394. Epub 2014 Mar 25.


Differential in situ expression of IL-17 in skin diseases.

Fischer-Stabauer M, Boehner A, Eyerich S, Carbone T, Traidl-Hoffmann C, Schmidt-Weber CB, Cavani A, Ring J, Hein R, Eyerich K.

Eur J Dermatol. 2012 Nov-Dec;22(6):781-4. doi: 10.1684/ejd.2012.1854.


IL-22 suppresses IFN-γ-mediated lung inflammation in asthmatic patients.

Pennino D, Bhavsar PK, Effner R, Avitabile S, Venn P, Quaranta M, Marzaioli V, Cifuentes L, Durham SR, Cavani A, Eyerich K, Chung KF, Schmidt-Weber CB, Eyerich S.

J Allergy Clin Immunol. 2013 Feb;131(2):562-70. doi: 10.1016/j.jaci.2012.09.036. Epub 2012 Nov 19.


Mutual antagonism of T cells causing psoriasis and atopic eczema.

Eyerich S, Onken AT, Weidinger S, Franke A, Nasorri F, Pennino D, Grosber M, Pfab F, Schmidt-Weber CB, Mempel M, Hein R, Ring J, Cavani A, Eyerich K.

N Engl J Med. 2011 Jul 21;365(3):231-8. doi: 10.1056/NEJMoa1104200. No abstract available.


Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis.

Liu L, Okada S, Kong XF, Kreins AY, Cypowyj S, Abhyankar A, Toubiana J, Itan Y, Audry M, Nitschke P, Masson C, Toth B, Flatot J, Migaud M, Chrabieh M, Kochetkov T, Bolze A, Borghesi A, Toulon A, Hiller J, Eyerich S, Eyerich K, Gulácsy V, Chernyshova L, Chernyshov V, Bondarenko A, Grimaldo RM, Blancas-Galicia L, Beas IM, Roesler J, Magdorf K, Engelhard D, Thumerelle C, Burgel PR, Hoernes M, Drexel B, Seger R, Kusuma T, Jansson AF, Sawalle-Belohradsky J, Belohradsky B, Jouanguy E, Bustamante J, Bué M, Karin N, Wildbaum G, Bodemer C, Lortholary O, Fischer A, Blanche S, Al-Muhsen S, Reichenbach J, Kobayashi M, Rosales FE, Lozano CT, Kilic SS, Oleastro M, Etzioni A, Traidl-Hoffmann C, Renner ED, Abel L, Picard C, Maródi L, Boisson-Dupuis S, Puel A, Casanova JL.

J Exp Med. 2011 Aug 1;208(8):1635-48. doi: 10.1084/jem.20110958. Epub 2011 Jul 4.


IL-22 and TNF-α represent a key cytokine combination for epidermal integrity during infection with Candida albicans.

Eyerich S, Wagener J, Wenzel V, Scarponi C, Pennino D, Albanesi C, Schaller M, Behrendt H, Ring J, Schmidt-Weber CB, Cavani A, Mempel M, Traidl-Hoffmann C, Eyerich K.

Eur J Immunol. 2011 Jul;41(7):1894-901. doi: 10.1002/eji.201041197. Epub 2011 May 20.


IL-17 and IL-22: siblings, not twins.

Eyerich S, Eyerich K, Cavani A, Schmidt-Weber C.

Trends Immunol. 2010 Sep;31(9):354-61. doi: 10.1016/ Epub 2010 Aug 4. Review.


IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes.

Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, Garcovich S, Traidl-Hoffmann C, Albanesi C, Cavani A.

J Immunol. 2010 May 1;184(9):4880-8. doi: 10.4049/jimmunol.0901767. Epub 2010 Mar 31.


Chronic mucocutaneous candidiasis, from bench to bedside.

Eyerich K, Eyerich S, Hiller J, Behrendt H, Traidl-Hoffmann C.

Eur J Dermatol. 2010 May-Jun;20(3):260-5. doi: 10.1684/ejd.2010.0910. Epub 2010 Feb 5. Review.


Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling.

Eyerich S, Eyerich K, Pennino D, Carbone T, Nasorri F, Pallotta S, Cianfarani F, Odorisio T, Traidl-Hoffmann C, Behrendt H, Durham SR, Schmidt-Weber CB, Cavani A.

J Clin Invest. 2009 Dec;119(12):3573-85. doi: 10.1172/JCI40202. Epub 2009 Nov 16.

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