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Items: 1 to 50 of 164

1.

Signals from the brain and olfactory epithelium control shaping of the mammalian nasal capsule cartilage.

Kaucka M, Petersen J, Tesarova M, Szarowska B, Kastriti ME, Xie M, Kicheva A, Annusver K, Kasper M, Symmons O, Pan L, Spitz F, Kaiser J, Hovorakova M, Zikmund T, Sunadome K, Matise MP, Wang H, Marklund U, Abdo H, Ernfors P, Maire P, Wurmser M, Chagin AS, Fried K, Adameyko I.

Elife. 2018 Jun 13;7. pii: e34465. doi: 10.7554/eLife.34465. [Epub ahead of print]

2.

Ca2+-binding protein NECAB2 facilitates inflammatory pain hypersensitivity.

Zhang MD, Su J, Adori C, Cinquina V, Malenczyk K, Girach F, Peng C, Ernfors P, Löw P, Borgius L, Kiehn O, Watanabe M, Uhlén M, Mitsios N, Mulder J, Harkany T, Hökfelt T.

J Clin Invest. 2018 Jun 12. pii: 120913. doi: 10.1172/JCI120913. [Epub ahead of print]

3.

Striking parallels between carotid body glomus cell and adrenal chromaffin cell development.

Hockman D, Adameyko I, Kaucka M, Barraud P, Otani T, Hunt A, Hartwig AC, Sock E, Waithe D, Franck MCM, Ernfors P, Ehinger S, Howard MJ, Brown N, Reese J, Baker CVH.

Dev Biol. 2018 May 25. pii: S0012-1606(17)30905-3. doi: 10.1016/j.ydbio.2018.05.016. [Epub ahead of print]

4.

NoRC Recruitment by H2A.X Deposition at rRNA Gene Promoter Limits Embryonic Stem Cell Proliferation.

Eleuteri B, Aranda S, Ernfors P.

Cell Rep. 2018 May 8;23(6):1853-1866. doi: 10.1016/j.celrep.2018.04.023.

5.

Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types.

Häring M, Zeisel A, Hochgerner H, Rinwa P, Jakobsson JET, Lönnerberg P, La Manno G, Sharma N, Borgius L, Kiehn O, Lagerström MC, Linnarsson S, Ernfors P.

Nat Neurosci. 2018 Jun;21(6):869-880. doi: 10.1038/s41593-018-0141-1. Epub 2018 Apr 23.

PMID:
29686262
6.

Evaluating vacquinol-1 in rats carrying glioblastoma models RG2 and NS1.

Ahlstedt J, Förnvik K, Zolfaghari S, Kwak D, Hammarström LGJ, Ernfors P, Salford LG, Redebrandt HN.

Oncotarget. 2018 Jan 3;9(9):8391-8399. doi: 10.18632/oncotarget.23842. eCollection 2018 Feb 2.

7.

Retraction Notice to: Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule.

Kitambi SS, Toledo EM, Usoskin D, Wee S, Harisankar A, Svensson R, Sigmundsson K, Kalderén C, Niklasson M, Kundu S, Aranda S, Westermark B, Uhrbom L, Andäng M, Damberg P, Nelander S, Arenas E, Artursson P, Walfridsson J, Nilsson KF, Hammarström LGJ, Ernfors P.

Cell. 2017 Jul 13;170(2):407. doi: 10.1016/j.cell.2017.06.044. No abstract available.

PMID:
28709005
8.

Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla.

Furlan A, Dyachuk V, Kastriti ME, Calvo-Enrique L, Abdo H, Hadjab S, Chontorotzea T, Akkuratova N, Usoskin D, Kamenev D, Petersen J, Sunadome K, Memic F, Marklund U, Fried K, Topilko P, Lallemend F, Kharchenko PV, Ernfors P, Adameyko I.

Science. 2017 Jul 7;357(6346). pii: eaal3753. doi: 10.1126/science.aal3753.

PMID:
28684471
9.

miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes.

Peng C, Li L, Zhang MD, Bengtsson Gonzales C, Parisien M, Belfer I, Usoskin D, Abdo H, Furlan A, Häring M, Lallemend F, Harkany T, Diatchenko L, Hökfelt T, Hjerling-Leffler J, Ernfors P.

Science. 2017 Jun 16;356(6343):1168-1171. doi: 10.1126/science.aam7671. Epub 2017 Jun 1.

PMID:
28572455
10.

The Oncolytic Efficacy and in Vivo Pharmacokinetics of [2-(4-Chlorophenyl)quinolin-4-yl](piperidine-2-yl)methanol (Vacquinol-1) Are Governed by Distinct Stereochemical Features.

Hammarström LG, Harmel RK, Granath M, Ringom R, Gravenfors Y, Färnegårdh K, Svensson PH, Wennman D, Lundin G, Roddis Y, Kitambi SS, Bernlind A, Lehmann F, Ernfors P.

J Med Chem. 2016 Sep 22;59(18):8577-92. doi: 10.1021/acs.jmedchem.6b01009. Epub 2016 Sep 8.

PMID:
27607569
11.

Visceral motor neuron diversity delineates a cellular basis for nipple- and pilo-erection muscle control.

Furlan A, La Manno G, Lübke M, Häring M, Abdo H, Hochgerner H, Kupari J, Usoskin D, Airaksinen MS, Oliver G, Linnarsson S, Ernfors P.

Nat Neurosci. 2016 Oct;19(10):1331-40. doi: 10.1038/nn.4376. Epub 2016 Aug 29.

PMID:
27571008
12.

Endogenous GABAA receptor activity suppresses glioma growth.

Blanchart A, Fernando R, Häring M, Assaife-Lopes N, Romanov RA, Andäng M, Harkany T, Ernfors P.

Oncogene. 2017 Feb 9;36(6):777-786. doi: 10.1038/onc.2016.245. Epub 2016 Jul 4.

PMID:
27375015
13.

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system.

Marques S, Zeisel A, Codeluppi S, van Bruggen D, Mendanha Falcão A, Xiao L, Li H, Häring M, Hochgerner H, Romanov RA, Gyllborg D, Muñoz Manchado A, La Manno G, Lönnerberg P, Floriddia EM, Rezayee F, Ernfors P, Arenas E, Hjerling-Leffler J, Harkany T, Richardson WD, Linnarsson S, Castelo-Branco G.

Science. 2016 Jun 10;352(6291):1326-1329. doi: 10.1126/science.aaf6463.

14.

New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress.

Ercilla A, Llopis A, Feu S, Aranda S, Ernfors P, Freire R, Agell N.

Nucleic Acids Res. 2016 Jun 2;44(10):4745-62. doi: 10.1093/nar/gkw132. Epub 2016 Mar 2.

15.

Three-dimensional Imaging Reveals New Compartments and Structural Adaptations in Odontoblasts.

Khatibi Shahidi M, Krivanek J, Kaukua N, Ernfors P, Hladik L, Kostal V, Masich S, Hampl A, Chubanov V, Gudermann T, Romanov RA, Harkany T, Adameyko I, Fried K.

J Dent Res. 2015 Jul;94(7):945-54. doi: 10.1177/0022034515580796. Epub 2015 Apr 2.

PMID:
25838461
16.

Mutations in the endothelin receptor type A cause mandibulofacial dysostosis with alopecia.

Gordon CT, Weaver KN, Zechi-Ceide RM, Madsen EC, Tavares AL, Oufadem M, Kurihara Y, Adameyko I, Picard A, Breton S, Pierrot S, Biosse-Duplan M, Voisin N, Masson C, Bole-Feysot C, Nitschké P, Delrue MA, Lacombe D, Guion-Almeida ML, Moura PP, Garib DG, Munnich A, Ernfors P, Hufnagel RB, Hopkin RJ, Kurihara H, Saal HM, Weaver DD, Katsanis N, Lyonnet S, Golzio C, Clouthier DE, Amiel J.

Am J Hum Genet. 2015 Apr 2;96(4):519-31. doi: 10.1016/j.ajhg.2015.01.015. Epub 2015 Mar 12.

17.

Nerves transport stem-like cells generating parasympathetic neurons.

Adameyko I, Ernfors P.

Cell Cycle. 2014;13(18):2805-6. doi: 10.4161/15384101.2014.959854. No abstract available.

18.

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing.

Usoskin D, Furlan A, Islam S, Abdo H, Lönnerberg P, Lou D, Hjerling-Leffler J, Haeggström J, Kharchenko O, Kharchenko PV, Linnarsson S, Ernfors P.

Nat Neurosci. 2015 Jan;18(1):145-53. doi: 10.1038/nn.3881. Epub 2014 Nov 24.

PMID:
25420068
19.

Cholestenoic acids regulate motor neuron survival via liver X receptors.

Theofilopoulos S, Griffiths WJ, Crick PJ, Yang S, Meljon A, Ogundare M, Kitambi SS, Lockhart A, Tuschl K, Clayton PT, Morris AA, Martinez A, Reddy MA, Martinuzzi A, Bassi MT, Honda A, Mizuochi T, Kimura A, Nittono H, De Michele G, Carbone R, Criscuolo C, Yau JL, Seckl JR, Schüle R, Schöls L, Sailer AW, Kuhle J, Fraidakis MJ, Gustafsson JÅ, Steffensen KR, Björkhem I, Ernfors P, Sjövall J, Arenas E, Wang Y.

J Clin Invest. 2014 Nov;124(11):4829-42. doi: 10.1172/JCI68506. Epub 2014 Oct 1.

20.

Glial origin of mesenchymal stem cells in a tooth model system.

Kaukua N, Shahidi MK, Konstantinidou C, Dyachuk V, Kaucka M, Furlan A, An Z, Wang L, Hultman I, Ahrlund-Richter L, Blom H, Brismar H, Lopes NA, Pachnis V, Suter U, Clevers H, Thesleff I, Sharpe P, Ernfors P, Fried K, Adameyko I.

Nature. 2014 Sep 25;513(7519):551-4. doi: 10.1038/nature13536. Epub 2014 Jul 27.

PMID:
25079316
21.

Neurodevelopment. Parasympathetic neurons originate from nerve-associated peripheral glial progenitors.

Dyachuk V, Furlan A, Shahidi MK, Giovenco M, Kaukua N, Konstantinidou C, Pachnis V, Memic F, Marklund U, Müller T, Birchmeier C, Fried K, Ernfors P, Adameyko I.

Science. 2014 Jul 4;345(6192):82-7. doi: 10.1126/science.1253281. Epub 2014 Jun 12.

22.

Identification of a large protein network involved in epigenetic transmission in replicating DNA of embryonic stem cells.

Aranda S, Rutishauser D, Ernfors P.

Nucleic Acids Res. 2014 Jun;42(11):6972-86. doi: 10.1093/nar/gku374. Epub 2014 May 22.

23.

Brain stem slice conditioned medium contains endogenous BDNF and GDNF that affect neural crest boundary cap cells in co-culture.

Kaiser A, Kale A, Novozhilova E, Siratirakun P, Aquino JB, Thonabulsombat C, Ernfors P, Olivius P.

Brain Res. 2014 May 30;1566:12-23. doi: 10.1016/j.brainres.2014.04.006. Epub 2014 Apr 16.

PMID:
24746495
24.

RETRACTED: Vulnerability of glioblastoma cells to catastrophic vacuolization and death induced by a small molecule.

Kitambi SS, Toledo EM, Usoskin D, Wee S, Harisankar A, Svensson R, Sigmundsson K, Kalderén C, Niklasson M, Kundu S, Aranda S, Westermark B, Uhrbom L, Andäng M, Damberg P, Nelander S, Arenas E, Artursson P, Walfridsson J, Forsberg Nilsson K, Hammarström LGJ, Ernfors P.

Cell. 2014 Apr 10;157(2):313-328. doi: 10.1016/j.cell.2014.02.021. Epub 2014 Mar 20. Retraction in: Cell. 2017 Jul 13;170(2):407.

25.

MYC proteins promote neuronal differentiation by controlling the mode of progenitor cell division.

Zinin N, Adameyko I, Wilhelm M, Fritz N, Uhlén P, Ernfors P, Henriksson MA.

EMBO Rep. 2014 Apr;15(4):383-91. doi: 10.1002/embr.201337424. Epub 2014 Mar 5.

26.

A local source of FGF initiates development of the unmyelinated lineage of sensory neurons.

Hadjab S, Franck MC, Wang Y, Sterzenbach U, Sharma A, Ernfors P, Lallemend F.

J Neurosci. 2013 Nov 6;33(45):17656-66. doi: 10.1523/JNEUROSCI.1090-13.2013.

27.

The transcription factor Hmx1 and growth factor receptor activities control sympathetic neurons diversification.

Furlan A, Lübke M, Adameyko I, Lallemend F, Ernfors P.

EMBO J. 2013 May 29;32(11):1613-25. doi: 10.1038/emboj.2013.85. Epub 2013 Apr 16.

28.

Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis.

Theofilopoulos S, Wang Y, Kitambi SS, Sacchetti P, Sousa KM, Bodin K, Kirk J, Saltó C, Gustafsson M, Toledo EM, Karu K, Gustafsson JÅ, Steffensen KR, Ernfors P, Sjövall J, Griffiths WJ, Arenas E.

Nat Chem Biol. 2013 Feb;9(2):126-33. doi: 10.1038/nchembio.1156. Epub 2012 Dec 23.

PMID:
23292650
29.

Positional differences of axon growth rates between sensory neurons encoded by Runx3.

Lallemend F, Sterzenbach U, Hadjab-Lallemend S, Aquino JB, Castelo-Branco G, Sinha I, Villaescusa JC, Levanon D, Wang Y, Franck MC, Kharchenko O, Adameyko I, Linnarsson S, Groner Y, Turner E, Ernfors P.

EMBO J. 2012 Sep 12;31(18):3718-29. doi: 10.1038/emboj.2012.228. Epub 2012 Aug 17.

30.

Molecular interactions underlying the specification of sensory neurons.

Lallemend F, Ernfors P.

Trends Neurosci. 2012 Jun;35(6):373-81. doi: 10.1016/j.tins.2012.03.006. Epub 2012 Apr 18. Review.

PMID:
22516617
31.

Small molecule screening platform for assessment of cardiovascular toxicity on adult zebrafish heart.

Kitambi SS, Nilsson ES, Sekyrova P, Ibarra C, Tekeoh GN, Andäng M, Ernfors P, Uhlén P.

BMC Physiol. 2012 Mar 26;12:3. doi: 10.1186/1472-6793-12-3.

32.

Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest.

Adameyko I, Lallemend F, Furlan A, Zinin N, Aranda S, Kitambi SS, Blanchart A, Favaro R, Nicolis S, Lübke M, Müller T, Birchmeier C, Suter U, Zaitoun I, Takahashi Y, Ernfors P.

Development. 2012 Jan;139(2):397-410. doi: 10.1242/dev.065581.

33.

Dependence on the transcription factor Shox2 for specification of sensory neurons conveying discriminative touch.

Abdo H, Li L, Lallemend F, Bachy I, Xu XJ, Rice FL, Ernfors P.

Eur J Neurosci. 2011 Nov;34(10):1529-41. doi: 10.1111/j.1460-9568.2011.07883.x.

PMID:
22103411
34.

The transcription factor Cux2 marks development of an A-delta sublineage of TrkA sensory neurons.

Bachy I, Franck MC, Li L, Abdo H, Pattyn A, Ernfors P.

Dev Biol. 2011 Dec 1;360(1):77-86. doi: 10.1016/j.ydbio.2011.09.007. Epub 2011 Sep 16.

35.

Cell cycle restriction by histone H2AX limits proliferation of adult neural stem cells.

Fernando RN, Eleuteri B, Abdelhady S, Nussenzweig A, Andäng M, Ernfors P.

Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5837-42. doi: 10.1073/pnas.1014993108. Epub 2011 Mar 21.

36.

Essential role of Ret for defining non-peptidergic nociceptor phenotypes and functions in the adult mouse.

Franck MC, Stenqvist A, Li L, Hao J, Usoskin D, Xu X, Wiesenfeld-Hallin Z, Ernfors P.

Eur J Neurosci. 2011 Apr;33(8):1385-400. doi: 10.1111/j.1460-9568.2011.07634.x. Epub 2011 Mar 14.

PMID:
21395865
37.

En masse in vitro functional profiling of the axonal mechanosensitivity of sensory neurons.

Usoskin D, Zilberter M, Linnarsson S, Hjerling-Leffler J, Uhlén P, Harkany T, Ernfors P.

Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16336-41. doi: 10.1073/pnas.0914705107. Epub 2010 Aug 24.

38.

Cellular origin and developmental mechanisms during the formation of skin melanocytes.

Ernfors P.

Exp Cell Res. 2010 May 1;316(8):1397-407. doi: 10.1016/j.yexcr.2010.02.042. Epub 2010 Mar 6. Review.

PMID:
20211169
39.

Dynamic expression of the TRPM subgroup of ion channels in developing mouse sensory neurons.

Staaf S, Franck MC, Marmigère F, Mattsson JP, Ernfors P.

Gene Expr Patterns. 2010 Jan;10(1):65-74. doi: 10.1016/j.gep.2009.10.003. Epub 2009 Oct 20.

PMID:
19850157
40.

Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin.

Adameyko I, Lallemend F, Aquino JB, Pereira JA, Topilko P, Müller T, Fritz N, Beljajeva A, Mochii M, Liste I, Usoskin D, Suter U, Birchmeier C, Ernfors P.

Cell. 2009 Oct 16;139(2):366-79. doi: 10.1016/j.cell.2009.07.049.

41.

The retinoic acid inducible Cas-family signaling protein Nedd9 regulates neural crest cell migration by modulating adhesion and actin dynamics.

Aquino JB, Lallemend F, Marmigère F, Adameyko II, Golemis EA, Ernfors P.

Neuroscience. 2009 Sep 15;162(4):1106-19. doi: 10.1016/j.neuroscience.2009.05.035. Epub 2009 May 21.

42.

Differential regulation of TRP channels in a rat model of neuropathic pain.

Staaf S, Oerther S, Lucas G, Mattsson JP, Ernfors P.

Pain. 2009 Jul;144(1-2):187-99. doi: 10.1016/j.pain.2009.04.013. Epub 2009 May 15.

PMID:
19446956
43.

Down regulation of TRPC1 by shRNA reduces mechanosensitivity in mouse dorsal root ganglion neurons in vitro.

Staaf S, Maxvall I, Lind U, Husmark J, Mattsson JP, Ernfors P, Pierrou S.

Neurosci Lett. 2009 Jun 19;457(1):3-7. doi: 10.1016/j.neulet.2009.03.082. Epub 2009 Mar 31.

PMID:
19429150
44.

Influence of environmental manipulation on exploratory behaviour in male BDNF knockout mice.

Zhu SW, Codita A, Bogdanovic N, Hjerling-Leffler J, Ernfors P, Winblad B, Dickins DW, Mohammed AH.

Behav Brain Res. 2009 Feb 11;197(2):339-46. doi: 10.1016/j.bbr.2008.09.032. Epub 2008 Oct 5.

PMID:
18951926
45.

Optimized mouse ES cell culture system by suspension growth in a fully defined medium.

Andäng M, Moliner A, Doege CA, Ibañez CF, Ernfors P.

Nat Protoc. 2008;3(6):1013-7. doi: 10.1038/nprot.2008.65.

PMID:
18536648
46.

Differential membrane compartmentalization of Ret by PTB-adaptor engagement.

Lundgren TK, Luebke M, Stenqvist A, Ernfors P.

FEBS J. 2008 May;275(9):2055-66. doi: 10.1111/j.1742-4658.2008.06360.x. Epub 2008 Mar 17.

47.

Subcellular receptor redistribution and enhanced microspike formation by a Ret receptor preferentially recruiting Dok.

Stenqvist A, Lundgren TK, Smith MJ, Hermanson O, Castelo-Branco G, Pawson T, Ernfors P.

Neurosci Lett. 2008 Apr 11;435(1):11-6. doi: 10.1016/j.neulet.2008.01.084. Epub 2008 Feb 20.

PMID:
18353552
48.

Differential expression and dynamic changes of murine NEDD9 in progenitor cells of diverse tissues.

Aquino JB, Marmigère F, Lallemend F, Lundgren TK, Villar MJ, Wegner M, Ernfors P.

Gene Expr Patterns. 2008 Apr;8(4):217-26. doi: 10.1016/j.gep.2008.01.001. Epub 2008 Jan 19.

PMID:
18282814
49.

Retrograde signaling onto Ret during motor nerve terminal maturation.

Baudet C, Pozas E, Adameyko I, Andersson E, Ericson J, Ernfors P.

J Neurosci. 2008 Jan 23;28(4):963-75. doi: 10.1523/JNEUROSCI.4489-07.2008.

50.

Cell migration by a FRS2-adaptor dependent membrane relocation of ret receptors.

Lundgren TK, Stenqvist A, Scott RP, Pawson T, Ernfors P.

J Cell Biochem. 2008 Jun 1;104(3):879-94. doi: 10.1002/jcb.21671.

PMID:
18189271

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