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Items: 1 to 50 of 160

1.

Development and plasticity of meningeal lymphatic vessels.

Antila S, Karaman S, Nurmi H, Airavaara M, Voutilainen MH, Mathivet T, Chilov D, Li Z, Koppinen T, Park JH, Fang S, Aspelund A, Saarma M, Eichmann A, Thomas JL, Alitalo K.

J Exp Med. 2017 Dec 4;214(12):3645-3667. doi: 10.1084/jem.20170391. Epub 2017 Nov 15.

PMID:
29141865
2.

Basic research: Where do new endothelial cells come from in the injured heart?

Greif DM, Eichmann A.

Nat Rev Cardiol. 2017 Sep;14(9):507-508. doi: 10.1038/nrcardio.2017.121. Epub 2017 Aug 3. No abstract available.

PMID:
28770866
3.

FGF-dependent metabolic control of vascular development.

Yu P, Wilhelm K, Dubrac A, Tung JK, Alves TC, Fang JS, Xie Y, Zhu J, Chen Z, De Smet F, Zhang J, Jin SW, Sun L, Sun H, Kibbey RG, Hirschi KK, Hay N, Carmeliet P, Chittenden TW, Eichmann A, Potente M, Simons M.

Nature. 2017 May 11;545(7653):224-228. doi: 10.1038/nature22322. Epub 2017 May 3.

4.

Alk2/ACVR1 and Alk3/BMPR1A Provide Essential Function for Bone Morphogenetic Protein-Induced Retinal Angiogenesis.

Lee HW, Chong DC, Ola R, Dunworth WP, Meadows S, Ka J, Kaartinen VM, Qyang Y, Cleaver O, Bautch VL, Eichmann A, Jin SW.

Arterioscler Thromb Vasc Biol. 2017 Apr;37(4):657-663. doi: 10.1161/ATVBAHA.116.308422. Epub 2017 Feb 23.

5.

PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia.

Ola R, Dubrac A, Han J, Zhang F, Fang JS, Larrivée B, Lee M, Urarte AA, Kraehling JR, Genet G, Hirschi KK, Sessa WC, Canals FV, Graupera M, Yan M, Young LH, Oh PS, Eichmann A.

Nat Commun. 2016 Nov 29;7:13650. doi: 10.1038/ncomms13650.

6.

The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization.

Zhang F, Prahst C, Mathivet T, Pibouin-Fragner L, Zhang J, Genet G, Tong R, Dubrac A, Eichmann A.

Nat Commun. 2016 Nov 24;7:13517. doi: 10.1038/ncomms13517.

7.

Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells.

Kraehling JR, Chidlow JH, Rajagopal C, Sugiyama MG, Fowler JW, Lee MY, Zhang X, Ramírez CM, Park EJ, Tao B, Chen K, Kuruvilla L, Larriveé B, Folta-Stogniew E, Ola R, Rotllan N, Zhou W, Nagle MW, Herz J, Williams KJ, Eichmann A, Lee WL, Fernández-Hernando C, Sessa WC.

Nat Commun. 2016 Nov 21;7:13516. doi: 10.1038/ncomms13516.

8.

Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia.

Baeyens N, Larrivée B, Ola R, Hayward-Piatkowskyi B, Dubrac A, Huang B, Ross TD, Coon BG, Min E, Tsarfati M, Tong H, Eichmann A, Schwartz MA.

J Cell Biol. 2016 Sep 26;214(7):807-16. doi: 10.1083/jcb.201603106. Epub 2016 Sep 19.

9.

BMP9/ALK1 inhibits neovascularization in mouse models of age-related macular degeneration.

Ntumba K, Akla N, Oh SP, Eichmann A, Larrivée B.

Oncotarget. 2016 Aug 30;7(35):55957-55969. doi: 10.18632/oncotarget.11182.

10.

Sympathetic Innervation Promotes Arterial Fate by Enhancing Endothelial ERK Activity.

Pardanaud L, Pibouin-Fragner L, Dubrac A, Mathivet T, English I, Brunet I, Simons M, Eichmann A.

Circ Res. 2016 Aug 19;119(5):607-20. doi: 10.1161/CIRCRESAHA.116.308473. Epub 2016 Jun 27.

11.

miR-182 Modulates Myocardial Hypertrophic Response Induced by Angiogenesis in Heart.

Li N, Hwangbo C, Jaba IM, Zhang J, Papangeli I, Han J, Mikush N, Larrivée B, Eichmann A, Chun HJ, Young LH, Tirziu D.

Sci Rep. 2016 Feb 18;6:21228. doi: 10.1038/srep21228.

12.

Netrin-1 Regulates Fibrocyte Accumulation in the Decellularized Fibrotic Sclerodermatous Lung Microenvironment and in Bleomycin-Induced Pulmonary Fibrosis.

Sun H, Zhu Y, Pan H, Chen X, Balestrini JL, Lam TT, Kanyo JE, Eichmann A, Gulati M, Fares WH, Bai H, Feghali-Bostwick CA, Gan Y, Peng X, Moore MW, White ES, Sava P, Gonzalez AL, Cheng Y, Niklason LE, Herzog EL.

Arthritis Rheumatol. 2016 May;68(5):1251-61. doi: 10.1002/art.39575.

13.

Angiopoietin-2 May Be Involved in the Resistance to Bevacizumab in Recurrent Glioblastoma.

Labussière M, Cheneau C, Prahst C, Gállego Pérez-Larraya J, Farina P, Lombardi G, Mokhtari K, Rahimian A, Delattre JY, Eichmann A, Sanson M.

Cancer Invest. 2016;34(1):39-44. doi: 10.3109/07357907.2015.1088948. Epub 2016 Jan 6. Erratum in: Cancer Invest. 2017 Feb 7;35(2):142.

PMID:
26735326
14.

Targeting NCK-Mediated Endothelial Cell Front-Rear Polarity Inhibits Neovascularization.

Dubrac A, Genet G, Ola R, Zhang F, Pibouin-Fragner L, Han J, Zhang J, Thomas JL, Chedotal A, Schwartz MA, Eichmann A.

Circulation. 2016 Jan 26;133(4):409-21. doi: 10.1161/CIRCULATIONAHA.115.017537. Epub 2015 Dec 9.

15.

NG2 glia are required for vessel network formation during embryonic development.

Minocha S, Valloton D, Brunet I, Eichmann A, Hornung JP, Lebrand C.

Elife. 2015 Dec 10;4. pii: e09102. doi: 10.7554/eLife.09102.

16.

Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.

Aspalter IM, Gordon E, Dubrac A, Ragab A, Narloch J, Vizán P, Geudens I, Collins RT, Franco CA, Abrahams CL, Thurston G, Fruttiger M, Rosewell I, Eichmann A, Gerhardt H.

Nat Commun. 2015 Jun 17;6:7264. doi: 10.1038/ncomms8264.

17.

Vascular Mural Cells Promote Noradrenergic Differentiation of Embryonic Sympathetic Neurons.

Fortuna V, Pardanaud L, Brunet I, Ola R, Ristori E, Santoro MM, Nicoli S, Eichmann A.

Cell Rep. 2015 Jun 23;11(11):1786-96. doi: 10.1016/j.celrep.2015.05.028. Epub 2015 Jun 11.

18.

Molecular controls of arterial morphogenesis.

Simons M, Eichmann A.

Circ Res. 2015 May 8;116(10):1712-24. doi: 10.1161/CIRCRESAHA.116.302953. Review.

19.

State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association.

Simons M, Alitalo K, Annex BH, Augustin HG, Beam C, Berk BC, Byzova T, Carmeliet P, Chilian W, Cooke JP, Davis GE, Eichmann A, Iruela-Arispe ML, Keshet E, Sinusas AJ, Ruhrberg C, Woo YJ, Dimmeler S; American Heart Association Council on Basic Cardiovascular Sciences and Council on Cardiovascular Surgery and Anesthesia.

Circ Res. 2015 May 22;116(11):e99-132. doi: 10.1161/RES.0000000000000054. Epub 2015 Apr 30. No abstract available.

20.

Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization.

Rama N, Dubrac A, Mathivet T, Ní Chárthaigh RA, Genet G, Cristofaro B, Pibouin-Fragner L, Ma L, Eichmann A, Chédotal A.

Nat Med. 2015 May;21(5):483-91. doi: 10.1038/nm.3849. Epub 2015 Apr 20.

21.

Vascular endothelial growth factor receptor 3 controls neural stem cell activation in mice and humans.

Han J, Calvo CF, Kang TH, Baker KL, Park JH, Parras C, Levittas M, Birba U, Pibouin-Fragner L, Fragner P, Bilguvar K, Duman RS, Nurmi H, Alitalo K, Eichmann AC, Thomas JL.

Cell Rep. 2015 Feb 24;10(7):1158-72. doi: 10.1016/j.celrep.2015.01.049. Epub 2015 Feb 19.

22.

Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point.

Baeyens N, Nicoli S, Coon BG, Ross TD, Van den Dries K, Han J, Lauridsen HM, Mejean CO, Eichmann A, Thomas JL, Humphrey JD, Schwartz MA.

Elife. 2015 Feb 2;4. doi: 10.7554/eLife.04645.

23.

Arterial innervation in development and disease.

Eichmann A, Brunet I.

Sci Transl Med. 2014 Sep 3;6(252):252ps9. doi: 10.1126/scitranslmed.3008910. Review.

PMID:
25186174
24.

Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates.

Lee MY, Luciano AK, Ackah E, Rodriguez-Vita J, Bancroft TA, Eichmann A, Simons M, Kyriakides TR, Morales-Ruiz M, Sessa WC.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12865-70. doi: 10.1073/pnas.1408472111. Epub 2014 Aug 18.

25.

PTP1b is a physiologic regulator of vascular endothelial growth factor signaling in endothelial cells.

Lanahan AA, Lech D, Dubrac A, Zhang J, Zhuang ZW, Eichmann A, Simons M.

Circulation. 2014 Sep 9;130(11):902-9. doi: 10.1161/CIRCULATIONAHA.114.009683. Epub 2014 Jun 30.

26.

Netrin-1 controls sympathetic arterial innervation.

Brunet I, Gordon E, Han J, Cristofaro B, Broqueres-You D, Liu C, Bouvrée K, Zhang J, del Toro R, Mathivet T, Larrivée B, Jagu J, Pibouin-Fragner L, Pardanaud L, Machado MJ, Kennedy TE, Zhuang Z, Simons M, Levy BI, Tessier-Lavigne M, Grenz A, Eltzschig H, Eichmann A.

J Clin Invest. 2014 Jul;124(7):3230-40. doi: 10.1172/JCI75181. Epub 2014 Jun 17.

27.

Tumor and endothelial cell hybrids participate in glioblastoma vasculature.

El Hallani S, Colin C, El Houfi Y, Idbaih A, Boisselier B, Marie Y, Ravassard P, Labussière M, Mokhtari K, Thomas JL, Delattre JY, Eichmann A, Sanson M.

Biomed Res Int. 2014;2014:827327. doi: 10.1155/2014/827327. Epub 2014 Apr 24.

28.

The H2.0-like homeobox transcription factor modulates yolk sac vascular remodeling in mouse embryos.

Prahst C, Kasaai B, Moraes F, Jahnsen ED, Larrivee B, Villegas D, Pardanaud L, Pibouin-Fragner L, Zhang F, Zaun HC, Eichmann A, Jones EA.

Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1468-76. doi: 10.1161/ATVBAHA.114.303626. Epub 2014 Apr 24.

29.

Vascular biology: Brain vessels squeezed to death.

Greif DM, Eichmann A.

Nature. 2014 Apr 3;508(7494):50-1. doi: 10.1038/nature13217. Epub 2014 Mar 26. No abstract available.

PMID:
24670635
30.

Transmembrane protein ESDN promotes endothelial VEGF signaling and regulates angiogenesis.

Nie L, Guo X, Esmailzadeh L, Zhang J, Asadi A, Collinge M, Li X, Kim JD, Woolls M, Jin SW, Dubrac A, Eichmann A, Simons M, Bender JR, Sadeghi MM.

J Clin Invest. 2013 Dec;123(12):5082-97. doi: 10.1172/JCI67752. Epub 2013 Nov 1.

31.

Endothelial signaling and the molecular basis of arteriovenous malformation.

Atri D, Larrivée B, Eichmann A, Simons M.

Cell Mol Life Sci. 2013 Sep 28. [Epub ahead of print]

32.

Need glucose to sprout: local metabolic control of angiogenesis.

Eichmann A, Simons M.

EMBO Mol Med. 2013 Oct;5(10):1459-61. doi: 10.1002/emmm.201303174. Epub 2013 Aug 27. No abstract available.

33.

Physiology. Lymphatics are in my veins.

Simons M, Eichmann A.

Science. 2013 Aug 9;341(6146):622-4. doi: 10.1126/science.1243452. No abstract available.

34.

Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models.

Cristofaro B, Shi Y, Faria M, Suchting S, Leroyer AS, Trindade A, Duarte A, Zovein AC, Iruela-Arispe ML, Nih LR, Kubis N, Henrion D, Loufrani L, Todiras M, Schleifenbaum J, Gollasch M, Zhuang ZW, Simons M, Eichmann A, le Noble F.

Development. 2013 Apr;140(8):1720-9. doi: 10.1242/dev.092304.

35.

Endothelial RAF1/ERK activation regulates arterial morphogenesis.

Deng Y, Larrivée B, Zhuang ZW, Atri D, Moraes F, Prahst C, Eichmann A, Simons M.

Blood. 2013 May 9;121(19):3988-96, S1-9. doi: 10.1182/blood-2012-12-474601. Epub 2013 Mar 25.

36.

Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells.

Thomas JL, Baker K, Han J, Calvo C, Nurmi H, Eichmann AC, Alitalo K.

Cell Mol Life Sci. 2013 May;70(10):1779-92. doi: 10.1007/s00018-013-1312-6. Epub 2013 Mar 12. Review.

37.

The power of VEGF (vascular endothelial growth factor) family molecules.

Thomas JL, Eichmann A.

Cell Mol Life Sci. 2013 May;70(10):1673-4. doi: 10.1007/s00018-013-1276-6. Epub 2013 Mar 12.

PMID:
23475064
38.

Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation.

Pluznick JL, Protzko RJ, Gevorgyan H, Peterlin Z, Sipos A, Han J, Brunet I, Wan LX, Rey F, Wang T, Firestein SJ, Yanagisawa M, Gordon JI, Eichmann A, Peti-Peterdi J, Caplan MJ.

Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4410-5. doi: 10.1073/pnas.1215927110. Epub 2013 Feb 11.

39.

Endothelial ERK signaling controls lymphatic fate specification.

Deng Y, Atri D, Eichmann A, Simons M.

J Clin Invest. 2013 Mar;123(3):1202-15. doi: 10.1172/JCI63034. Epub 2013 Feb 8.

40.

Ezh2 orchestrates topographic migration and connectivity of mouse precerebellar neurons.

Di Meglio T, Kratochwil CF, Vilain N, Loche A, Vitobello A, Yonehara K, Hrycaj SM, Roska B, Peters AH, Eichmann A, Wellik D, Ducret S, Rijli FM.

Science. 2013 Jan 11;339(6116):204-7. doi: 10.1126/science.1229326.

41.

Endothelial nuclear factor-κB-dependent regulation of arteriogenesis and branching.

Tirziu D, Jaba IM, Yu P, Larrivée B, Coon BG, Cristofaro B, Zhuang ZW, Lanahan AA, Schwartz MA, Eichmann A, Simons M.

Circulation. 2012 Nov 27;126(22):2589-600. doi: 10.1161/CIRCULATIONAHA.112.119321. Epub 2012 Oct 22.

42.

Molecular parallels between neural and vascular development.

Eichmann A, Thomas JL.

Cold Spring Harb Perspect Med. 2013 Jan 1;3(1):a006551. doi: 10.1101/cshperspect.a006551. Review.

43.

Context-dependent proangiogenic function of bone morphogenetic protein signaling is mediated by disabled homolog 2.

Kim JD, Kang H, Larrivée B, Lee MY, Mettlen M, Schmid SL, Roman BL, Qyang Y, Eichmann A, Jin SW.

Dev Cell. 2012 Aug 14;23(2):441-8. doi: 10.1016/j.devcel.2012.07.007.

44.

Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages.

Camelo S, Raoul W, Lavalette S, Calippe B, Cristofaro B, Levy O, Houssier M, Sulpice E, Jonet L, Klein C, Devevre E, Thuret G, Duarte A, Eichmann A, Leconte L, Guillonneau X, Sennlaub F.

Angiogenesis. 2012 Dec;15(4):609-22. doi: 10.1007/s10456-012-9290-0. Epub 2012 Aug 7. Erratum in: Angiogenesis. 2013 Apr;16(2):479-80.

45.

Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.

Bouvrée K, Brunet I, Del Toro R, Gordon E, Prahst C, Cristofaro B, Mathivet T, Xu Y, Soueid J, Fortuna V, Miura N, Aigrot MS, Maden CH, Ruhrberg C, Thomas JL, Eichmann A.

Circ Res. 2012 Aug 3;111(4):437-45. doi: 10.1161/CIRCRESAHA.112.269316. Epub 2012 Jun 21.

46.

"On-target" cardiac effects of anticancer drugs: lessons from new biology.

Simons M, Eichmann A.

J Am Coll Cardiol. 2012 Aug 14;60(7):626-7. doi: 10.1016/j.jacc.2012.01.069. Epub 2012 Jun 13. No abstract available.

47.

ALK1 signaling inhibits angiogenesis by cooperating with the Notch pathway.

Larrivée B, Prahst C, Gordon E, del Toro R, Mathivet T, Duarte A, Simons M, Eichmann A.

Dev Cell. 2012 Mar 13;22(3):489-500. doi: 10.1016/j.devcel.2012.02.005.

48.

VEGF signaling inside vascular endothelial cells and beyond.

Eichmann A, Simons M.

Curr Opin Cell Biol. 2012 Apr;24(2):188-93. doi: 10.1016/j.ceb.2012.02.002. Epub 2012 Feb 25. Review.

49.

Extraembryonic origin of circulating endothelial cells.

Pardanaud L, Eichmann A.

PLoS One. 2011;6(10):e25889. doi: 10.1371/journal.pone.0025889. Epub 2011 Oct 14.

50.

VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling.

Tammela T, Zarkada G, Nurmi H, Jakobsson L, Heinolainen K, Tvorogov D, Zheng W, Franco CA, Murtomäki A, Aranda E, Miura N, Ylä-Herttuala S, Fruttiger M, Mäkinen T, Eichmann A, Pollard JW, Gerhardt H, Alitalo K.

Nat Cell Biol. 2011 Sep 11;13(10):1202-13. doi: 10.1038/ncb2331.

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