Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 62

1.

GEMMs Are a Gem When it Comes to Defining the Role of HIF2α in Mucinous Cystic Neoplasms.

Boyle KA, Dwinell MB.

Cell Mol Gastroenterol Hepatol. 2017 Dec 8;5(2):165-166. doi: 10.1016/j.jcmgh.2017.11.008. eCollection 2018. No abstract available.

2.

Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models.

Tsai S, McOlash L, Palen K, Johnson B, Duris C, Yang Q, Dwinell MB, Hunt B, Evans DB, Gershan J, James MA.

BMC Cancer. 2018 Mar 27;18(1):335. doi: 10.1186/s12885-018-4238-4.

3.

Corrigendum to 'A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds' [REDOX 14C (2017) 316-327].

Kalyanaraman B, Cheng G, Hardy M, Ouari O, Lopez M, Joseph J, Zielonka J, Dwinell MB.

Redox Biol. 2018 Jun;16:426-427. doi: 10.1016/j.redox.2018.03.001. Epub 2018 Mar 13. No abstract available.

4.

A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds.

Kalyanaraman B, Cheng G, Hardy M, Ouari O, Lopez M, Joseph J, Zielonka J, Dwinell MB.

Redox Biol. 2018 Apr;14:316-327. doi: 10.1016/j.redox.2017.09.020. Epub 2017 Sep 29. Review. Erratum in: Redox Biol. 2018 Mar 13;:.

5.

Differences in Sulfotyrosine Binding amongst CXCR1 and CXCR2 Chemokine Ligands.

Moussouras NA, Getschman AE, Lackner ER, Veldkamp CT, Dwinell MB, Volkman BF.

Int J Mol Sci. 2017 Sep 3;18(9). pii: E1894. doi: 10.3390/ijms18091894.

6.

CCR7 Sulfotyrosine Enhances CCL21 Binding.

Phillips AJ, Taleski D, Koplinski CA, Getschman AE, Moussouras NA, Richard AM, Peterson FC, Dwinell MB, Volkman BF, Payne RJ, Veldkamp CT.

Int J Mol Sci. 2017 Aug 25;18(9). pii: E1857. doi: 10.3390/ijms18091857.

7.

Modified Metformin as a More Potent Anticancer Drug: Mitochondrial Inhibition, Redox Signaling, Antiproliferative Effects and Future EPR Studies.

Kalyanaraman B, Cheng G, Hardy M, Ouari O, Sikora A, Zielonka J, Dwinell MB.

Cell Biochem Biophys. 2017 Dec;75(3-4):311-317. doi: 10.1007/s12013-017-0796-3. Epub 2017 Apr 21.

PMID:
28429253
8.

Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation.

Ziarek JJ, Kleist AB, London N, Raveh B, Montpas N, Bonneterre J, St-Onge G, DiCosmo-Ponticello CJ, Koplinski CA, Roy I, Stephens B, Thelen S, Veldkamp CT, Coffman FD, Cohen MC, Dwinell MB, Thelen M, Peterson FC, Heveker N, Volkman BF.

Sci Signal. 2017 Mar 21;10(471). pii: eaah5756. doi: 10.1126/scisignal.aah5756.

9.

Cancer cell chemokines direct chemotaxis of activated stellate cells in pancreatic ductal adenocarcinoma.

Roy I, Boyle KA, Vonderhaar EP, Zimmerman NP, Gorse E, Mackinnon AC, Hwang RF, Franco-Barraza J, Cukierman E, Tsai S, Evans DB, Dwinell MB.

Lab Invest. 2017 Mar;97(3):302-317. doi: 10.1038/labinvest.2016.146. Epub 2017 Jan 16.

10.

Exploiting agonist biased signaling of chemokines to target cancer.

Roy I, Getschman AE, Volkman BF, Dwinell MB.

Mol Carcinog. 2017 Mar;56(3):804-813. doi: 10.1002/mc.22571. Epub 2016 Oct 4.

11.

E-cadherin re-expression shows in vivo evidence for mesenchymal to epithelial transition in clonal metastatic breast tumor cells.

Palen K, Weber J, Dwinell MB, Johnson BD, Ramchandran R, Gershan JA.

Oncotarget. 2016 Jul 12;7(28):43363-43375. doi: 10.18632/oncotarget.9715.

12.

Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells.

Cheng G, Zielonka J, Ouari O, Lopez M, McAllister D, Boyle K, Barrios CS, Weber JJ, Johnson BD, Hardy M, Dwinell MB, Kalyanaraman B.

Cancer Res. 2016 Jul 1;76(13):3904-15. doi: 10.1158/0008-5472.CAN-15-2534. Epub 2016 May 23.

13.

Generation and characterization of mice harboring a conditional CXCL12 allele.

Hillmer RE, Boisvert JP, Cucciare MJ, Dwinell MB, Joksimovic M.

Int J Dev Biol. 2015;59(4-6):205-9. doi: 10.1387/ijdb.140348mj.

14.

Pancreatic Cancer Cell Migration and Metastasis Is Regulated by Chemokine-Biased Agonism and Bioenergetic Signaling.

Roy I, McAllister DM, Gorse E, Dixon K, Piper CT, Zimmerman NP, Getschman AE, Tsai S, Engle DD, Evans DB, Volkman BF, Kalyanaraman B, Dwinell MB.

Cancer Res. 2015 Sep 1;75(17):3529-42. doi: 10.1158/0008-5472.CAN-14-2645.

15.

Correction: Astrocytes Directly Influence Tumor Cell Invasion and Metastasis In Vivo.

Wang L, Cossette SM, Rarick KR, Gershan J, Dwinell MB, Harder DR, Ramchandran R.

PLoS One. 2015 Aug 31;10(8):e0137369. doi: 10.1371/journal.pone.0137369. eCollection 2015. No abstract available.

16.

p38γ MAPK Is a Therapeutic Target for Triple-Negative Breast Cancer by Stimulation of Cancer Stem-Like Cell Expansion.

Qi X, Yin N, Ma S, Lepp A, Tang J, Jing W, Johnson B, Dwinell MB, Chitambar CR, Chen G.

Stem Cells. 2015 Sep;33(9):2738-47. doi: 10.1002/stem.2068. Epub 2015 Jun 23.

17.

Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism.

Cheng G, Zielonka J, McAllister D, Hardy M, Ouari O, Joseph J, Dwinell MB, Kalyanaraman B.

Cancer Lett. 2015 Aug 28;365(1):96-106. doi: 10.1016/j.canlet.2015.05.016. Epub 2015 May 21.

18.

CXM: a new tool for mapping breast cancer risk in the tumor microenvironment.

Flister MJ, Endres BT, Rudemiller N, Sarkis AB, Santarriaga S, Roy I, Lemke A, Geurts AM, Moreno C, Ran S, Tsaih SW, De Pons J, Carlson DF, Tan W, Fahrenkrug SC, Lazarova Z, Lazar J, North PE, LaViolette PS, Dwinell MB, Shull JD, Jacob HJ.

Cancer Res. 2014 Nov 15;74(22):6419-29. doi: 10.1158/0008-5472.CAN-13-3212. Epub 2014 Aug 29.

19.

Profiling and targeting of cellular bioenergetics: inhibition of pancreatic cancer cell proliferation.

Cheng G, Zielonka J, McAllister D, Tsai S, Dwinell MB, Kalyanaraman B.

Br J Cancer. 2014 Jul 8;111(1):85-93. doi: 10.1038/bjc.2014.272. Epub 2014 May 27.

20.

Chemokines and chemokine receptors: update on utility and challenges for the clinician.

Roy I, Evans DB, Dwinell MB.

Surgery. 2014 Jun;155(6):961-73. doi: 10.1016/j.surg.2014.02.006. Epub 2014 Feb 8. Review. No abstract available.

21.

CXCL12 chemokine expression suppresses human pancreatic cancer growth and metastasis.

Roy I, Zimmerman NP, Mackinnon AC, Tsai S, Evans DB, Dwinell MB.

PLoS One. 2014 Mar 4;9(3):e90400. doi: 10.1371/journal.pone.0090400. eCollection 2014.

22.

Astrocytes directly influence tumor cell invasion and metastasis in vivo.

Wang L, Cossette SM, Rarick KR, Gershan J, Dwinell MB, Harder DR, Ramchandran R.

PLoS One. 2013 Dec 4;8(12):e80933. doi: 10.1371/journal.pone.0080933. eCollection 2013. Erratum in: PLoS One. 2015;10(8):e0137369.

23.

Chemokines in colitis: microRNA control.

Roy I, Veldkamp CT, Volkman BF, Dwinell MB.

Gut. 2014 Aug;63(8):1202-4. doi: 10.1136/gutjnl-2013-305886. Epub 2013 Oct 18. No abstract available.

24.

Cyclic AMP regulates the migration and invasion potential of human pancreatic cancer cells.

Zimmerman NP, Roy I, Hauser AD, Wilson JM, Williams CL, Dwinell MB.

Mol Carcinog. 2015 Mar;54(3):203-15. doi: 10.1002/mc.22091. Epub 2013 Sep 24.

25.

Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death.

Cheng G, Zielonka J, McAllister DM, Mackinnon AC Jr, Joseph J, Dwinell MB, Kalyanaraman B.

BMC Cancer. 2013 Jun 13;13:285. doi: 10.1186/1471-2407-13-285.

26.

An adenosine-mediated signaling pathway suppresses prenylation of the GTPase Rap1B and promotes cell scattering.

Ntantie E, Gonyo P, Lorimer EL, Hauser AD, Schuld N, McAllister D, Kalyanaraman B, Dwinell MB, Auchampach JA, Williams CL.

Sci Signal. 2013 May 28;6(277):ra39. doi: 10.1126/scisignal.2003374.

27.

CXCR4 negatively regulates keratinocyte proliferation in IL-23-mediated psoriasiform dermatitis.

Takekoshi T, Wu X, Mitsui H, Tada Y, Kao MC, Sato S, Dwinell MB, Hwang ST.

J Invest Dermatol. 2013 Nov;133(11):2530-2537. doi: 10.1038/jid.2013.151. Epub 2013 Mar 25.

28.

E-cadherin is critical for collective sheet migration and is regulated by the chemokine CXCL12 protein during restitution.

Hwang S, Zimmerman NP, Agle KA, Turner JR, Kumar SN, Dwinell MB.

J Biol Chem. 2012 Jun 22;287(26):22227-40. doi: 10.1074/jbc.M112.367979. Epub 2012 May 1.

29.

Cyclic AMP dysregulates intestinal epithelial cell restitution through PKA and RhoA.

Zimmerman NP, Kumar SN, Turner JR, Dwinell MB.

Inflamm Bowel Dis. 2012 Jun;18(6):1081-91. doi: 10.1002/ibd.21898. Epub 2011 Oct 12.

30.

Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways.

Drury LJ, Ziarek JJ, Gravel S, Veldkamp CT, Takekoshi T, Hwang ST, Heveker N, Volkman BF, Dwinell MB.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17655-60. doi: 10.1073/pnas.1101133108. Epub 2011 Oct 11.

31.

Chemokine stimulation promotes enterocyte migration through laminin-specific integrins.

Agle KA, Vongsa RA, Dwinell MB.

Am J Physiol Gastrointest Liver Physiol. 2011 Dec;301(6):G968-80. doi: 10.1152/ajpgi.00208.2011. Epub 2011 Sep 15.

32.

Targeted intestinal epithelial deletion of the chemokine receptor CXCR4 reveals important roles for extracellular-regulated kinase-1/2 in restitution.

Zimmerman NP, Vongsa RA, Faherty SL, Salzman NH, Dwinell MB.

Lab Invest. 2011 Jul;91(7):1040-55. doi: 10.1038/labinvest.2011.77. Epub 2011 May 2.

33.

CXCL12 chemokine expression and secretion regulates colorectal carcinoma cell anoikis through Bim-mediated intrinsic apoptosis.

Drury LJ, Wendt MK, Dwinell MB.

PLoS One. 2010 Sep 22;5(9):e12895. doi: 10.1371/journal.pone.0012895.

34.

Calcium mobilization triggered by the chemokine CXCL12 regulates migration in wounded intestinal epithelial monolayers.

Agle KA, Vongsa RA, Dwinell MB.

J Biol Chem. 2010 May 21;285(21):16066-75. doi: 10.1074/jbc.M109.061416. Epub 2010 Mar 26.

35.

CCR6 regulation of the actin cytoskeleton orchestrates human beta defensin-2- and CCL20-mediated restitution of colonic epithelial cells.

Vongsa RA, Zimmerman NP, Dwinell MB.

J Biol Chem. 2009 Apr 10;284(15):10034-45. doi: 10.1074/jbc.M805289200. Epub 2009 Feb 20.

36.

Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cells.

Wendt MK, Drury LJ, Vongsa RA, Dwinell MB.

Gastroenterology. 2008 Aug;135(2):508-17. doi: 10.1053/j.gastro.2008.05.033. Epub 2008 May 15.

37.

Chemokines and chemokine receptors in mucosal homeostasis at the intestinal epithelial barrier in inflammatory bowel disease.

Zimmerman NP, Vongsa RA, Wendt MK, Dwinell MB.

Inflamm Bowel Dis. 2008 Jul;14(7):1000-11. doi: 10.1002/ibd.20480. Review.

38.

Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cells.

Wendt MK, Cooper AN, Dwinell MB.

Oncogene. 2008 Feb 28;27(10):1461-71. Epub 2007 Sep 3.

PMID:
17724466
39.

Rho activation regulates CXCL12 chemokine stimulated actin rearrangement and restitution in model intestinal epithelia.

Moyer RA, Wendt MK, Johanesen PA, Turner JR, Dwinell MB.

Lab Invest. 2007 Aug;87(8):807-17. Epub 2007 Jun 18.

40.

Mucosal immunity.

Dwinell MB, Kagnoff MF.

Curr Opin Gastroenterol. 1999 Jan;15(1):33-8.

PMID:
17023915
41.
42.

Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis.

Wendt MK, Johanesen PA, Kang-Decker N, Binion DG, Shah V, Dwinell MB.

Oncogene. 2006 Aug 17;25(36):4986-97. Epub 2006 Mar 27.

43.
44.

Chemokine receptor CCR6 transduces signals that activate p130Cas and alter cAMP-stimulated ion transport in human intestinal epithelial cells.

Yang CC, Ogawa H, Dwinell MB, McCole DF, Eckmann L, Kagnoff MF.

Am J Physiol Cell Physiol. 2005 Feb;288(2):C321-8. Epub 2004 Oct 13.

45.

CXCL12 activation of CXCR4 regulates mucosal host defense through stimulation of epithelial cell migration and promotion of intestinal barrier integrity.

Smith JM, Johanesen PA, Wendt MK, Binion DG, Dwinell MB.

Am J Physiol Gastrointest Liver Physiol. 2005 Feb;288(2):G316-26. Epub 2004 Sep 9.

46.

Mucosal angiogenesis regulation by CXCR4 and its ligand CXCL12 expressed by human intestinal microvascular endothelial cells.

Heidemann J, Ogawa H, Rafiee P, Lügering N, Maaser C, Domschke W, Binion DG, Dwinell MB.

Am J Physiol Gastrointest Liver Physiol. 2004 Jun;286(6):G1059-68. Epub 2004 Feb 5.

47.

SDF-1/CXCL12 regulates cAMP production and ion transport in intestinal epithelial cells via CXCR4.

Dwinell MB, Ogawa H, Barrett KE, Kagnoff MF.

Am J Physiol Gastrointest Liver Physiol. 2004 May;286(5):G844-50. Epub 2003 Dec 18.

48.

Isolation and characterization of human esophageal microvascular endothelial cells: mechanisms of inflammatory activation.

Rafiee P, Ogawa H, Heidemann J, Li MS, Aslam M, Lamirand TH, Fisher PJ, Graewin SJ, Dwinell MB, Johnson CP, Shaker R, Binion DG.

Am J Physiol Gastrointest Liver Physiol. 2003 Dec;285(6):G1277-92. Epub 2003 Aug 14.

49.

Immunobiology of epithelial chemokines in the intestinal mucosa.

Dwinell MB, Johanesen PA, Smith JM.

Surgery. 2003 Jun;133(6):601-7. Review. No abstract available.

PMID:
12796725
50.

Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2.

Heidemann J, Ogawa H, Dwinell MB, Rafiee P, Maaser C, Gockel HR, Otterson MF, Ota DM, Lugering N, Domschke W, Binion DG.

J Biol Chem. 2003 Mar 7;278(10):8508-15. Epub 2002 Dec 20.

Supplemental Content

Loading ...
Support Center