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Items: 16


Coactivation of Estrogen Receptor and IKKβ Induces a Dormant Metastatic Phenotype in ER-Positive Breast Cancer.

El-Shennawy L, Dubrovskyi O, Kastrati I, Danes JM, Zhang Y, Whiteley HE, Creighton CJ, Frasor J.

Cancer Res. 2018 Feb 15;78(4):974-984. doi: 10.1158/0008-5472.CAN-17-1686. Epub 2017 Dec 11.


Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation.

Calvert AE, Chalastanis A, Wu Y, Hurley LA, Kouri FM, Bi Y, Kachman M, May JL, Bartom E, Hua Y, Mishra RK, Schiltz GE, Dubrovskyi O, Mazar AP, Peter ME, Zheng H, James CD, Burant CF, Chandel NS, Davuluri RV, Horbinski C, Stegh AH.

Cell Rep. 2017 May 30;19(9):1858-1873. doi: 10.1016/j.celrep.2017.05.014.


Melanoma Cells Block PEDF Production in Fibroblasts to Induce the Tumor-Promoting Phenotype of Cancer-Associated Fibroblasts.

Nwani NG, Deguiz ML, Jimenez B, Vinokour E, Dubrovskyi O, Ugolkov A, Mazar AP, Volpert OV.

Cancer Res. 2016 Apr 15;76(8):2265-76. doi: 10.1158/0008-5472.CAN-15-2468. Epub 2016 Feb 26.


Identification of HDAC6-Selective Inhibitors of Low Cancer Cell Cytotoxicity.

Gaisina IN, Tueckmantel W, Ugolkov A, Shen S, Hoffen J, Dubrovskyi O, Mazar A, Schoon RA, Billadeau D, Kozikowski AP.

ChemMedChem. 2016 Jan 5;11(1):81-92. doi: 10.1002/cmdc.201500456. Epub 2015 Nov 23.


Patient-Derived Tumor Xenografts Are Susceptible to Formation of Human Lymphocytic Tumors.

Bondarenko G, Ugolkov A, Rohan S, Kulesza P, Dubrovskyi O, Gursel D, Mathews J, O'Halloran TV, Wei JJ, Mazar AP.

Neoplasia. 2015 Sep;17(9):735-741. doi: 10.1016/j.neo.2015.09.004.


GRP78 is a novel receptor initiating a vascular barrier protective response to oxidized phospholipids.

Birukova AA, Singleton PA, Gawlak G, Tian X, Mirzapoiazova T, Mambetsariev B, Dubrovskyi O, Oskolkova OV, Bochkov VN, Birukov KG.

Mol Biol Cell. 2014 Jul 1;25(13):2006-16. doi: 10.1091/mbc.E13-12-0743. Epub 2014 May 14.


Identification of a new epitope in uPAR as a target for the cancer therapeutic monoclonal antibody ATN-658, a structural homolog of the uPAR binding integrin CD11b (αM).

Xu X, Cai Y, Wei Y, Donate F, Juarez J, Parry G, Chen L, Meehan EJ, Ahn RW, Ugolkov A, Dubrovskyi O, O'Halloran TV, Huang M, Mazar AP.

PLoS One. 2014 Jan 21;9(1):e85349. doi: 10.1371/journal.pone.0085349. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e99911.


Phosphorylation of Gβ is crucial for efficient chemotropism in yeast.

Deflorio R, Brett ME, Waszczak N, Apollinari E, Metodiev MV, Dubrovskyi O, Eddington D, Arkowitz RA, Stone DE.

J Cell Sci. 2013 Jul 15;126(Pt 14):2997-3009. doi: 10.1242/jcs.112797. Epub 2013 Apr 23.


Measurement of local permeability at subcellular level in cell models of agonist- and ventilator-induced lung injury.

Dubrovskyi O, Birukova AA, Birukov KG.

Lab Invest. 2013 Feb;93(2):254-63. doi: 10.1038/labinvest.2012.159. Epub 2012 Nov 19.


Identification of paxillin domains interacting with β-catenin.

Dubrovskyi O, Tian X, Poroyko V, Yakubov B, Birukova AA, Birukov KG.

FEBS Lett. 2012 Jul 30;586(16):2294-9. doi: 10.1016/j.febslet.2012.06.016. Epub 2012 Jun 20.


VE-cadherin trans-interactions modulate Rac activation and enhancement of lung endothelial barrier by iloprost.

Birukova AA, Tian Y, Dubrovskyi O, Zebda N, Sarich N, Tian X, Wang Y, Birukov KG.

J Cell Physiol. 2012 Oct;227(10):3405-16. doi: 10.1002/jcp.24041.


Focal adhesion kinase regulation of mechanotransduction and its impact on endothelial cell functions.

Zebda N, Dubrovskyi O, Birukov KG.

Microvasc Res. 2012 Jan;83(1):71-81. doi: 10.1016/j.mvr.2011.06.007. Epub 2011 Jun 29. Review.


Afadin controls p120-catenin-ZO-1 interactions leading to endothelial barrier enhancement by oxidized phospholipids.

Birukova AA, Fu P, Wu T, Dubrovskyi O, Sarich N, Poroyko V, Birukov KG.

J Cell Physiol. 2012 May;227(5):1883-90. doi: 10.1002/jcp.22916.


p190RhoGAP mediates protective effects of oxidized phospholipids in the models of ventilator-induced lung injury.

Birukova AA, Zebda N, Cokic I, Fu P, Wu T, Dubrovskyi O, Birukov KG.

Exp Cell Res. 2011 Apr 1;317(6):859-72. doi: 10.1016/j.yexcr.2010.11.011. Epub 2010 Nov 25.


Atrial natriuretic peptide attenuates LPS-induced lung vascular leak: role of PAK1.

Birukova AA, Xing J, Fu P, Yakubov B, Dubrovskyi O, Fortune JA, Klibanov AM, Birukov KG.

Am J Physiol Lung Cell Mol Physiol. 2010 Nov;299(5):L652-63. doi: 10.1152/ajplung.00202.2009. Epub 2010 Aug 20.


Dse1 may control cross talk between the pheromone and filamentation pathways in yeast.

Draper E, Dubrovskyi O, Bar EE, Stone DE.

Curr Genet. 2009 Dec;55(6):611-21. doi: 10.1007/s00294-009-0274-6. Epub 2009 Oct 10.


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