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Items: 47

1.

A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens.

Chang AY, Dao T, Gejman RS, Jarvis CA, Scott A, Dubrovsky L, Mathias MD, Korontsvit T, Zakhaleva V, Curcio M, Hendrickson RC, Liu C, Scheinberg DA.

J Clin Invest. 2017 Sep 1;127(9):3557. doi: 10.1172/JCI96860. Epub 2017 Sep 1. No abstract available.

2.

A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens.

Chang AY, Dao T, Gejman RS, Jarvis CA, Scott A, Dubrovsky L, Mathias MD, Korontsvit T, Zakhaleva V, Curcio M, Hendrickson RC, Liu C, Scheinberg DA.

J Clin Invest. 2017 Jun 30;127(7):2705-2718. doi: 10.1172/JCI92335. Epub 2017 Jun 19.

3.

Use of Primary Macrophages for Searching Novel Immunocorrectors.

Nikiforov NG, Elizova NV, Bukrinsky M, Dubrovsky L, Makeev VJ, Wakabayashi Y, Liu P, Foxx KK, Kruth HS, Jin X, Zakiev ER, Orekhov AN.

Curr Pharm Des. 2017;23(6):915-920. doi: 10.2174/1381612823666170125110128. Review.

PMID:
28124601
4.

Cold Atmospheric Plasma Inhibits HIV-1 Replication in Macrophages by Targeting Both the Virus and the Cells.

Volotskova O, Dubrovsky L, Keidar M, Bukrinsky M.

PLoS One. 2016 Oct 26;11(10):e0165322. doi: 10.1371/journal.pone.0165322. eCollection 2016.

5.

HIV-1 Integrates Widely throughout the Genome of the Human Blood Fluke Schistosoma mansoni.

Suttiprapa S, Rinaldi G, Tsai IJ, Mann VH, Dubrovsky L, Yan HB, Holroyd N, Huckvale T, Durrant C, Protasio AV, Pushkarsky T, Iordanskiy S, Berriman M, Bukrinsky MI, Brindley PJ.

PLoS Pathog. 2016 Oct 20;12(10):e1005931. doi: 10.1371/journal.ppat.1005931. eCollection 2016 Oct.

6.

Mechanisms of leukemia resistance to antibody dependent cellular cytotoxicity.

Dubrovsky L, Brea EJ, Pankov D, Casey E, Dao T, Liu C, Scheinberg DA.

Oncoimmunology. 2016 Aug 3;5(9):e1211221. eCollection 2016.

7.

Interaction Between HIV-1 Nef and Calnexin: From Modeling to Small Molecule Inhibitors Reversing HIV-Induced Lipid Accumulation.

Hunegnaw R, Vassylyeva M, Dubrovsky L, Pushkarsky T, Sviridov D, Anashkina AA, Üren A, Brichacek B, Vassylyev DG, Adzhubei AA, Bukrinsky M.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1758-71. doi: 10.1161/ATVBAHA.116.307997. Epub 2016 Jul 28.

8.

T cell receptor mimic antibodies for cancer therapy.

Dubrovsky L, Dao T, Gejman RS, Brea EJ, Chang AY, Oh CY, Casey E, Pankov D, Scheinberg DA.

Oncoimmunology. 2015 Jun 1;5(1):e1049803. eCollection 2016. Review.

9.

Therapeutic bispecific T-cell engager antibody targeting the intracellular oncoprotein WT1.

Dao T, Pankov D, Scott A, Korontsvit T, Zakhaleva V, Xu Y, Xiang J, Yan S, de Morais Guerreiro MD, Veomett N, Dubrovsky L, Curcio M, Doubrovina E, Ponomarev V, Liu C, O'Reilly RJ, Scheinberg DA.

Nat Biotechnol. 2015 Oct;33(10):1079-86. doi: 10.1038/nbt.3349. Epub 2015 Sep 21.

10.

HIV infection induces structural and functional changes in high density lipoproteins.

Siegel MO, Borkowska AG, Dubrovsky L, Roth M, Welti R, Roberts AD, Parenti DM, Simon GL, Sviridov D, Simmens S, Bukrinsky M, Fitzgerald ML.

Atherosclerosis. 2015 Nov;243(1):19-29. doi: 10.1016/j.atherosclerosis.2015.08.036. Epub 2015 Aug 29.

11.

Stimulation of Liver X Receptor Has Potent Anti-HIV Effects in a Humanized Mouse Model of HIV Infection.

Ramezani A, Dubrovsky L, Pushkarsky T, Sviridov D, Karandish S, Raj DS, Fitzgerald ML, Bukrinsky M.

J Pharmacol Exp Ther. 2015 Sep;354(3):376-83. doi: 10.1124/jpet.115.224485. Epub 2015 Jun 30.

12.

HIV-1 infection of macrophages induces retention of cholesterol transporter ABCA1 in the endoplasmic reticulum.

Brichacek B, Darwish C, Popratiloff A, Dubrovsky L, Bukrinsky M.

AIDS Res Hum Retroviruses. 2014 Oct;30(10):947-8. doi: 10.1089/aid.2014.0156. Epub 2014 Sep 8. No abstract available.

13.

HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexin.

Jennelle L, Hunegnaw R, Dubrovsky L, Pushkarsky T, Fitzgerald ML, Sviridov D, Popratiloff A, Brichacek B, Bukrinsky M.

J Biol Chem. 2014 Oct 17;289(42):28870-84. doi: 10.1074/jbc.M114.583591. Epub 2014 Aug 28.

14.

Therapeutic efficacy of an Fc-enhanced TCR-like antibody to the intracellular WT1 oncoprotein.

Veomett N, Dao T, Liu H, Xiang J, Pankov D, Dubrovsky L, Whitten JA, Park SM, Korontsvit T, Zakhaleva V, Casey E, Curcio M, Kharas MG, O'Reilly RJ, Liu C, Scheinberg DA.

Clin Cancer Res. 2014 Aug 1;20(15):4036-46. doi: 10.1158/1078-0432.CCR-13-2756. Epub 2014 May 21.

15.

A TCR-mimic antibody to WT1 bypasses tyrosine kinase inhibitor resistance in human BCR-ABL+ leukemias.

Dubrovsky L, Pankov D, Brea EJ, Dao T, Scott A, Yan S, O'Reilly RJ, Liu C, Scheinberg DA.

Blood. 2014 May 22;123(21):3296-304. doi: 10.1182/blood-2014-01-549022. Epub 2014 Apr 10.

16.

Liver X receptor agonist inhibits HIV-1 replication and prevents HIV-induced reduction of plasma HDL in humanized mouse model of HIV infection.

Dubrovsky L, Van Duyne R, Senina S, Guendel I, Pushkarsky T, Sviridov D, Kashanchi F, Bukrinsky M.

Biochem Biophys Res Commun. 2012 Mar 2;419(1):95-8. doi: 10.1016/j.bbrc.2012.01.137. Epub 2012 Feb 4.

17.

HIV-1 Nef mobilizes lipid rafts in macrophages through a pathway that competes with ABCA1-dependent cholesterol efflux.

Cui HL, Grant A, Mukhamedova N, Pushkarsky T, Jennelle L, Dubrovsky L, Gaus K, Fitzgerald ML, Sviridov D, Bukrinsky M.

J Lipid Res. 2012 Apr;53(4):696-708. doi: 10.1194/jlr.M023119. Epub 2012 Jan 19.

18.

Analysis of pediatric autologous PBSC apheresis and transplant: age is a major factor affecting post-transplant toxicity.

Dubrovsky L, McCarter RJ, Fry TJ, Wong E, Cheng Y, Perez-Albuerne ED.

Pediatr Blood Cancer. 2012 Aug;59(2):301-5. doi: 10.1002/pbc.24026. Epub 2011 Dec 16.

PMID:
22180259
19.

CD34⁺ collection efficiency as a function of blood volumes processed in pediatric autologous peripheral blood stem cell collection.

Dubrovsky L, Wong EC, Perez-Albuerne E, Loechelt B, Kamani N, Sande J, Mintz K, Paul W, Luban NL, Rood BR, Fry T.

J Clin Apher. 2011;26(3):131-7. doi: 10.1002/jca.20281. Epub 2011 Feb 3.

PMID:
21294153
20.

HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome.

Li G, Elder RT, Dubrovsky L, Liang D, Pushkarsky T, Chiu K, Fan T, Sire J, Bukrinsky M, Zhao RY.

PLoS One. 2010 Jun 29;5(6):e11371. doi: 10.1371/journal.pone.0011371.

21.

Stimulation of the liver X receptor pathway inhibits HIV-1 replication via induction of ATP-binding cassette transporter A1.

Morrow MP, Grant A, Mujawar Z, Dubrovsky L, Pushkarsky T, Kiselyeva Y, Jennelle L, Mukhamedova N, Remaley AT, Kashanchi F, Sviridov D, Bukrinsky M.

Mol Pharmacol. 2010 Aug;78(2):215-25. doi: 10.1124/mol.110.065029. Epub 2010 May 17.

22.

HIV-1 transforms the monocyte plasma membrane proteome.

Kadiu I, Wang T, Schlautman JD, Dubrovsky L, Ciborowski P, Bukrinsky M, Gendelman HE.

Cell Immunol. 2009;258(1):44-58. doi: 10.1016/j.cellimm.2009.03.012. Epub 2009 Apr 8.

23.

Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation.

Wu W, Kehn-Hall K, Pedati C, Zweier L, Castro I, Klase Z, Dowd CS, Dubrovsky L, Bukrinsky M, Kashanchi F.

Virol J. 2008 Mar 18;5:41. doi: 10.1186/1743-422X-5-41.

24.

Human immunodeficiency virus impairs reverse cholesterol transport from macrophages.

Mujawar Z, Rose H, Morrow MP, Pushkarsky T, Dubrovsky L, Mukhamedova N, Fu Y, Dart A, Orenstein JM, Bobryshev YV, Bukrinsky M, Sviridov D.

PLoS Biol. 2006 Oct;4(11):e365.

25.

Long-term changes of serum chemokine levels in vaccinated military personnel.

Brichacek B, Vanpouille C, Trachtenberg AJ, Pushkarsky T, Dubrovsky L, Martin G, Simon G, Bukrinsky M.

BMC Immunol. 2006 Sep 11;7:21.

26.

Oxadiazols: a new class of rationally designed anti-human immunodeficiency virus compounds targeting the nuclear localization signal of the viral matrix protein.

Haffar O, Dubrovsky L, Lowe R, Berro R, Kashanchi F, Godden J, Vanpouille C, Bajorath J, Bukrinsky M.

J Virol. 2005 Oct;79(20):13028-36.

27.

Heat shock protein 70 protects cells from cell cycle arrest and apoptosis induced by human immunodeficiency virus type 1 viral protein R.

Iordanskiy S, Zhao Y, Dubrovsky L, Iordanskaya T, Chen M, Liang D, Bukrinsky M.

J Virol. 2004 Sep;78(18):9697-704.

28.

Sequence context modulates the stability of a GxxxG-mediated transmembrane helix-helix dimer.

Doura AK, Kobus FJ, Dubrovsky L, Hibbard E, Fleming KG.

J Mol Biol. 2004 Aug 20;341(4):991-8.

PMID:
15289100
29.

Heat-shock protein 70 exerts opposing effects on Vpr-dependent and Vpr-independent HIV-1 replication in macrophages.

Iordanskiy S, Zhao Y, DiMarzio P, Agostini I, Dubrovsky L, Bukrinsky M.

Blood. 2004 Sep 15;104(6):1867-72. Epub 2004 May 27.

30.

Inhibition of HIV-1 nuclear import via schiff base formation with arylene bis(methylketone) compounds.

Al-Abed Y, Dubrovsky L, Ruzsicska B, Seepersaud M, Bukrinsky M.

Bioorg Med Chem Lett. 2002 Nov 4;12(21):3117-9.

PMID:
12372514
31.

Phosphorylation of Vpr regulates HIV type 1 nuclear import and macrophage infection.

Agostini I, Popov S, Hao T, Li JH, Dubrovsky L, Chaika O, Chaika N, Lewis R, Bukrinsky M.

AIDS Res Hum Retroviruses. 2002 Mar 1;18(4):283-8.

PMID:
11860675
32.

Lipopolysaccharide stimulates HIV-1 entry and degradation in human macrophages.

Pushkarsky T, Dubrovsky L, Bukrinsky M.

J Endotoxin Res. 2001;7(4):271-6.

PMID:
11717580
33.

CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A.

Pushkarsky T, Zybarth G, Dubrovsky L, Yurchenko V, Tang H, Guo H, Toole B, Sherry B, Bukrinsky M.

Proc Natl Acad Sci U S A. 2001 May 22;98(11):6360-5. Epub 2001 May 15.

34.
35.

Nitric oxide regulates MIP-1alpha expression in primary macrophages and T lymphocytes: implications for anti-HIV-1 response.

Sherry B, Schmidtmayerova H, Zybarth G, Dubrovsky L, Raabe T, Bukrinsky M.

Mol Med. 2000 Jun;6(6):542-9.

36.

Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex.

Agostini I, Popov S, Li J, Dubrovsky L, Hao T, Bukrinsky M.

Exp Cell Res. 2000 Sep 15;259(2):398-403.

PMID:
10964507
37.

Two nuclear localization signals in the HIV-1 matrix protein regulate nuclear import of the HIV-1 pre-integration complex.

Haffar OK, Popov S, Dubrovsky L, Agostini I, Tang H, Pushkarsky T, Nadler SG, Bukrinsky M.

J Mol Biol. 2000 Jun 2;299(2):359-68.

PMID:
10860744
38.

Lipopolysaccharide inhibits HIV-1 infection of monocyte- derived macrophages through direct and sustained down-regulation of CC chemokine receptor 5.

Franchin G, Zybarth G, Dai WW, Dubrovsky L, Reiling N, Schmidtmayerova H, Bukrinsky M, Sherry B.

J Immunol. 2000 Mar 1;164(5):2592-601.

39.

Role of cyclophilin A in the uptake of HIV-1 by macrophages and T lymphocytes.

Sherry B, Zybarth G, Alfano M, Dubrovsky L, Mitchell R, Rich D, Ulrich P, Bucala R, Cerami A, Bukrinsky M.

Proc Natl Acad Sci U S A. 1998 Feb 17;95(4):1758-63.

40.

The critical role of p38 MAP kinase in T cell HIV-1 replication.

Cohen PS, Schmidtmayerova H, Dennis J, Dubrovsky L, Sherry B, Wang H, Bukrinsky M, Tracey KJ.

Mol Med. 1997 May;3(5):339-46.

41.

Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation.

Popov S, Dubrovsky L, Lee MA, Pennathur S, Haffar O, aL-Abed Y, Tonge P, Ulrich P, Rexach M, Blobel G, Cerami A, Bukrinsky M.

Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11859-64.

42.

A critical role of nitric oxide in human immunodeficiency virus type 1-induced hyperresponsiveness of cultured monocytes.

Bukrinsky M, Schmidtmayerova H, Zybarth G, Dubrovsky L, Sherry B, Enikolopov G.

Mol Med. 1996 Jul;2(4):460-8.

43.

Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: implications for recruitment of leukocytes into brain and lymph nodes.

Schmidtmayerova H, Nottet HS, Nuovo G, Raabe T, Flanagan CR, Dubrovsky L, Gendelman HE, Cerami A, Bukrinsky M, Sherry B.

Proc Natl Acad Sci U S A. 1996 Jan 23;93(2):700-4.

44.

Anti-idiotypic antibody to the V3 domain of gp120 binds to vimentin: a possible role of intermediate filaments in the early steps of HIV-1 infection cycle.

Thomas EK, Connelly RJ, Pennathur S, Dubrovsky L, Haffar OK, Bukrinsky MI.

Viral Immunol. 1996;9(2):73-87.

PMID:
8822624
45.

Prospective study of lactose absorption during cancer chemotherapy: feasibility of a yogurt-supplemented diet in lactose malabsorbers.

Pettoello-Mantovani M, Guandalini S, diMartino L, Corvino C, Indolfi P, Casale F, Giuliano M, Dubrovsky L, Di Tullio MT.

J Pediatr Gastroenterol Nutr. 1995 Feb;20(2):189-95.

PMID:
7714685
46.

Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease.

Bukrinsky MI, Nottet HS, Schmidtmayerova H, Dubrovsky L, Flanagan CR, Mullins ME, Lipton SA, Gendelman HE.

J Exp Med. 1995 Feb 1;181(2):735-45.

47.

Nuclear localization signal of HIV-1 as a novel target for therapeutic intervention.

Dubrovsky L, Ulrich P, Nuovo GJ, Manogue KR, Cerami A, Bukrinsky M.

Mol Med. 1995 Jan;1(2):217-30.

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