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Items: 36

1.

Dynarrestin, a Novel Inhibitor of Cytoplasmic Dynein.

Höing S, Yeh TY, Baumann M, Martinez NE, Habenberger P, Kremer L, Drexler HCA, Küchler P, Reinhardt P, Choidas A, Zischinsky ML, Zischinsky G, Nandini S, Ledray AP, Ketcham SA, Reinhardt L, Abo-Rady M, Glatza M, King SJ, Nussbaumer P, Ziegler S, Klebl B, Schroer TA, Schöler HR, Waldmann H, Sterneckert J.

Cell Chem Biol. 2018 Apr 19;25(4):357-369.e6. doi: 10.1016/j.chembiol.2017.12.014. Epub 2018 Jan 27.

PMID:
29396292
2.

Proteomic Analysis of Mouse Oocytes Identifies PRMT7 as a Reprogramming Factor that Replaces SOX2 in the Induction of Pluripotent Stem Cells.

Wang B, Pfeiffer MJ, Drexler HC, Fuellen G, Boiani M.

J Proteome Res. 2016 Aug 5;15(8):2407-21. doi: 10.1021/acs.jproteome.5b01083. Epub 2016 Jul 12.

3.

An evolutionary approach uncovers a diverse response of tRNA 2-thiolation to elevated temperatures in yeast.

Alings F, Sarin LP, Fufezan C, Drexler HC, Leidel SA.

RNA. 2015 Feb;21(2):202-12. doi: 10.1261/rna.048199.114. Epub 2014 Dec 12.

4.

The inhibition of tyrosine kinase receptor signalling in leiomyosarcoma cells using the small molecule kinase inhibitor PTK787/ZK222584 (Vatalanib®).

Gaumann AK, Drexler HC, Lang SA, Stoeltzing O, Diermeier-Daucher S, Buchdunger E, Wood J, Bold G, Breier G.

Int J Oncol. 2014 Dec;45(6):2267-77. doi: 10.3892/ijo.2014.2683. Epub 2014 Sep 29.

5.

Esm1 modulates endothelial tip cell behavior and vascular permeability by enhancing VEGF bioavailability.

Rocha SF, Schiller M, Jing D, Li H, Butz S, Vestweber D, Biljes D, Drexler HC, Nieminen-Kelhä M, Vajkoczy P, Adams S, Benedito R, Adams RH.

Circ Res. 2014 Aug 29;115(6):581-90. doi: 10.1161/CIRCRESAHA.115.304718. Epub 2014 Jul 23.

6.

Maternal age effect on mouse oocytes: new biological insight from proteomic analysis.

Schwarzer C, Siatkowski M, Pfeiffer MJ, Baeumer N, Drexler HC, Wang B, Fuellen G, Boiani M.

Reproduction. 2014 Jul;148(1):55-72. doi: 10.1530/REP-14-0126. Epub 2014 Mar 31.

7.

Toll-like receptor 9 protects non-immune cells from stress by modulating mitochondrial ATP synthesis through the inhibition of SERCA2.

Shintani Y, Drexler HC, Kioka H, Terracciano CM, Coppen SR, Imamura H, Akao M, Nakai J, Wheeler AP, Higo S, Nakayama H, Takashima S, Yashiro K, Suzuki K.

EMBO Rep. 2014 Apr;15(4):438-45. doi: 10.1002/embr.201337945. Epub 2014 Mar 7.

8.

SILAC proteomics of planarians identifies Ncoa5 as a conserved component of pluripotent stem cells.

Böser A, Drexler HC, Reuter H, Schmitz H, Wu G, Schöler HR, Gentile L, Bartscherer K.

Cell Rep. 2013 Nov 27;5(4):1142-55. doi: 10.1016/j.celrep.2013.10.035. Epub 2013 Nov 21.

9.

A unique Oct4 interface is crucial for reprogramming to pluripotency.

Esch D, Vahokoski J, Groves MR, Pogenberg V, Cojocaru V, Vom Bruch H, Han D, Drexler HC, Araúzo-Bravo MJ, Ng CK, Jauch R, Wilmanns M, Schöler HR.

Nat Cell Biol. 2013 Mar;15(3):295-301. doi: 10.1038/ncb2680. Epub 2013 Feb 3.

PMID:
23376973
10.

Spatial regulation of VEGF receptor endocytosis in angiogenesis.

Nakayama M, Nakayama A, van Lessen M, Yamamoto H, Hoffmann S, Drexler HC, Itoh N, Hirose T, Breier G, Vestweber D, Cooper JA, Ohno S, Kaibuchi K, Adams RH.

Nat Cell Biol. 2013 Mar;15(3):249-60. doi: 10.1038/ncb2679. Epub 2013 Jan 27.

11.

On marathons and Sprints: an integrated quantitative proteomics and transcriptomics analysis of differences between slow and fast muscle fibers.

Drexler HC, Ruhs A, Konzer A, Mendler L, Bruckskotten M, Looso M, Günther S, Boettger T, Krüger M, Braun T.

Mol Cell Proteomics. 2012 Jun;11(6):M111.010801. doi: 10.1074/mcp.M111.010801. Epub 2011 Dec 30.

12.

Proteomic analysis of mouse oocytes reveals 28 candidate factors of the "reprogrammome".

Pfeiffer MJ, Siatkowski M, Paudel Y, Balbach ST, Baeumer N, Crosetto N, Drexler HC, Fuellen G, Boiani M.

J Proteome Res. 2011 May 6;10(5):2140-53. doi: 10.1021/pr100706k. Epub 2011 Mar 29.

PMID:
21344949
13.

Synergistic apoptosis induction in leukemic cells by the phosphatase inhibitor salubrinal and proteasome inhibitors.

Drexler HC.

PLoS One. 2009;4(1):e4161. doi: 10.1371/journal.pone.0004161. Epub 2009 Jan 8.

14.

Analysis of changes in the proteome of HL-60 promyeloid leukemia cells induced by the proteasome inhibitor PSI.

Choi MR, Najafi F, Safa AR, Drexler HC.

Biochem Pharmacol. 2008 Jun 15;75(12):2276-88. doi: 10.1016/j.bcp.2008.03.017. Epub 2008 Apr 7.

15.

Regulation of pyruvate kinase type M2 by A-Raf: a possible glycolytic stop or go mechanism.

Mazurek S, Drexler HC, Troppmair J, Eigenbrodt E, Rapp UR.

Anticancer Res. 2007 Nov-Dec;27(6B):3963-71.

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Unique vascular phenotypes following over-expression of individual VEGFA isoforms from the developing lens.

Mitchell CA, Rutland CS, Walker M, Nasir M, Foss AJ, Stewart C, Gerhardt H, Konerding MA, Risau W, Drexler HC.

Angiogenesis. 2006;9(4):209-24. Epub 2006 Nov 16.

PMID:
17109192
20.

[Autocrine stimulation of receptor-tyrosine kinases (RTK) in human tumor cell lines in vitro: therapeutic implications].

Gaumann A, Groot M, Drexler HC, Breier G.

Verh Dtsch Ges Pathol. 2003;87:232-9. German.

PMID:
16888917
21.
22.

Programmed cell death and the proteasome.

Drexler HC.

Apoptosis. 1998;3(1):1-7.

PMID:
14646512
23.

The role of p27Kip1 in proteasome inhibitor induced apoptosis.

Drexler HC.

Cell Cycle. 2003 Sep-Oct;2(5):438-41. Review.

PMID:
12963837
25.

Myocytes die by multiple mechanisms in failing human hearts.

Kostin S, Pool L, Elsässer A, Hein S, Drexler HC, Arnon E, Hayakawa Y, Zimmermann R, Bauer E, Klövekorn WP, Schaper J.

Circ Res. 2003 Apr 18;92(7):715-24. Epub 2003 Mar 20.

26.

p38 MAP kinase--a molecular switch between VEGF-induced angiogenesis and vascular hyperpermeability.

Issbrücker K, Marti HH, Hippenstiel S, Springmann G, Voswinckel R, Gaumann A, Breier G, Drexler HC, Suttorp N, Clauss M.

FASEB J. 2003 Feb;17(2):262-4. Epub 2002 Dec 18.

PMID:
12490545
27.

Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPK1) converts an activator of NFkappaB into an inhibitor of NFkappaB.

Arnold R, Liou J, Drexler HC, Weiss A, Kiefer F.

J Biol Chem. 2001 May 4;276(18):14675-84. Epub 2001 Jan 29.

28.

Inhibition of proteasome function induces programmed cell death in proliferating endothelial cells.

Drexler HC, Risau W, Konerding MA.

FASEB J. 2000 Jan;14(1):65-77.

PMID:
10627281
30.

Leptin, the product of Ob gene, promotes angiogenesis.

Bouloumié A, Drexler HC, Lafontan M, Busse R.

Circ Res. 1998 Nov 16;83(10):1059-66.

31.

Regulation of endothelial monocyte-activating polypeptide II release by apoptosis.

Knies UE, Behrensdorf HA, Mitchell CA, Deutsch U, Risau W, Drexler HC, Clauss M.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12322-7.

32.

Fritz: a secreted frizzled-related protein that inhibits Wnt activity.

Mayr T, Deutsch U, Kühl M, Drexler HC, Lottspeich F, Deutzmann R, Wedlich D, Risau W.

Mech Dev. 1997 Apr;63(1):109-25.

33.

Activation of the cell death program by inhibition of proteasome function.

Drexler HC.

Proc Natl Acad Sci U S A. 1997 Feb 4;94(3):855-60.

35.

Expression of a specific marker of avian programmed cell death in both apoptosis and necrosis.

Fernandez PA, Rotello RJ, Rangini Z, Doupe A, Drexler HC, Yuan J.

Proc Natl Acad Sci U S A. 1994 Aug 30;91(18):8641-5.

36.

Prevention of vertebrate neuronal death by the crmA gene.

Gagliardini V, Fernandez PA, Lee RK, Drexler HC, Rotello RJ, Fishman MC, Yuan J.

Science. 1994 Feb 11;263(5148):826-8. Erratum in: Science 1994 Jun 3;264(5164):1388.

PMID:
8303301

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