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Items: 1 to 50 of 57

1.

Patient experiences of a physiotherapy-led multidisciplinary rehabilitative intervention after successful treatment for oesophago-gastric cancer.

Bennett AE, O'Neill L, Connolly D, Guinan EM, Boland L, Doyle SL, O'Sullivan J, Reynolds JV, Hussey J.

Support Care Cancer. 2018 Feb 18. doi: 10.1007/s00520-018-4112-6. [Epub ahead of print]

PMID:
29455302
2.

Prevalence of age-related macular degeneration associated genetic risk factors and 4-year progression data in the Irish population.

Connolly E, Rhatigan M, O'Halloran AM, Muldrew KA, Chakravarthy U, Cahill M, Kenny RA, Doyle SL.

Br J Ophthalmol. 2018 Feb 16. pii: bjophthalmol-2017-311673. doi: 10.1136/bjophthalmol-2017-311673. [Epub ahead of print]

PMID:
29453225
3.

Extratumoral PD-1 blockade does not perpetuate obesity-associated inflammation in esophageal adenocarcinoma.

Galvin KC, Conroy MJ, Doyle SL, Dunne MR, Fahey R, Foley E, O'Sullivan KE, Doherty DG, Geoghegan JG, Ravi N, O'Farrelly C, Reynolds JV, Lysaght J.

Cancer Lett. 2018 Apr 1;418:230-238. doi: 10.1016/j.canlet.2018.01.039. Epub 2018 Jan 12.

PMID:
29339209
4.

Sarcopenia during neoadjuvant therapy for oesophageal cancer: characterising the impact on muscle strength and physical performance.

Guinan EM, Doyle SL, Bennett AE, O'Neill L, Gannon J, Elliott JA, O'Sullivan J, Reynolds JV, Hussey J.

Support Care Cancer. 2018 May;26(5):1569-1576. doi: 10.1007/s00520-017-3993-0. Epub 2017 Dec 2.

PMID:
29197960
5.

Impact of supplemental home enteral feeding postesophagectomy on nutrition, body composition, quality of life, and patient satisfaction.

Donohoe CL, Healy LA, Fanning M, Doyle SL, Hugh AM, Moore J, Ravi N, Reynolds JV.

Dis Esophagus. 2017 Sep 1;30(9):1-9. doi: 10.1093/dote/dox063.

PMID:
28859364
6.

Sarcopenia: Prevalence, and Impact on Operative and Oncologic Outcomes in the Multimodal Management of Locally Advanced Esophageal Cancer.

Elliott JA, Doyle SL, Murphy CF, King S, Guinan EM, Beddy P, Ravi N, Reynolds JV.

Ann Surg. 2017 Nov;266(5):822-830. doi: 10.1097/SLA.0000000000002398.

PMID:
28796017
7.

Comparative Performance of Pediatric Weight Estimation Techniques: A Human Factor Errors Analysis.

Abdel-Rahman SM, Jacobsen R, Watts JL, Doyle SL, OʼMalley DM, Hefner TD, Dowd MD.

Pediatr Emerg Care. 2017 Aug;33(8):548-552. doi: 10.1097/PEC.0000000000000543.

PMID:
28777773
8.

Does Prolonged Enteral Feeding With Supplemental Omega-3 Fatty Acids Impact on Recovery Post-esophagectomy: Results of a Randomized Double-Blind Trial.

Healy LA, Ryan A, Doyle SL, Ní Bhuachalla ÉB, Cushen S, Segurado R, Murphy T, Ravi N, Donohoe CL, Reynolds JV.

Ann Surg. 2017 Nov;266(5):720-728. doi: 10.1097/SLA.0000000000002390.

PMID:
28742713
9.

Reduced fitness and physical functioning are long-term sequelae after curative treatment for esophageal cancer: a matched control study.

Gannon JA, Guinan EM, Doyle SL, Beddy P, Reynolds JV, Hussey J.

Dis Esophagus. 2017 Aug 1;30(8):1-7. doi: 10.1093/dote/dox018.

PMID:
28575241
10.

Impact of visceral obesity and metabolic syndrome on the postoperative immune, inflammatory, and endocrine response following surgery for esophageal adenocarcinoma.

Doyle SL, Mongan AM, Donohoe CL, Pidgeon GP, Sherlock M, Reynolds JV, Lysaght J.

Dis Esophagus. 2017 Jun 1;30(6):1-11. doi: 10.1093/dote/dox008.

PMID:
28475745
11.

MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction.

Gray P, Dunne A, Brikos C, Jefferies CA, Doyle SL, O Neill LA.

J Biol Chem. 2016 Dec 9;291(50):26240. No abstract available.

12.

Effects of a multimodal rehabilitation programme on inflammation and oxidative stress in oesophageal cancer survivors: the ReStOre feasibility study.

Guinan EM, Doyle SL, O'Neill L, Dunne MR, Foley EK, O'Sullivan J, Reynolds JV, Hussey J.

Support Care Cancer. 2017 Mar;25(3):749-756. doi: 10.1007/s00520-016-3455-0. Epub 2016 Nov 3.

PMID:
27807666
13.

Interleukin-33 regulates tissue remodelling and inhibits angiogenesis in the eye.

Theodoropoulou S, Copland DA, Liu J, Wu J, Gardner PJ, Ozaki E, Doyle SL, Campbell M, Dick AD.

J Pathol. 2017 Jan;241(1):45-56. doi: 10.1002/path.4816. Epub 2016 Nov 16.

14.

Weight Loss, Satiety, and the Postprandial Gut Hormone Response After Esophagectomy: A Prospective Study.

Elliott JA, Docherty NG, Eckhardt HG, Doyle SL, Guinan EM, Ravi N, Reynolds JV, Roux CWL.

Ann Surg. 2017 Jul;266(1):82-90. doi: 10.1097/SLA.0000000000001918.

PMID:
27455150
15.

Parallel Profiles of Inflammatory and Effector Memory T Cells in Visceral Fat and Liver of Obesity-Associated Cancer Patients.

Conroy MJ, Galvin KC, Doyle SL, Kavanagh ME, Mongan AM, Cannon A, Moore GY, Reynolds JV, Lysaght J.

Inflammation. 2016 Oct;39(5):1729-36. doi: 10.1007/s10753-016-0407-2.

PMID:
27423204
16.

The microenvironment of visceral adipose tissue and liver alter natural killer cell viability and function.

Conroy MJ, Fitzgerald V, Doyle SL, Channon S, Useckaite Z, Gilmartin N, O'Farrelly C, Ravi N, Reynolds JV, Lysaght J.

J Leukoc Biol. 2016 Dec;100(6):1435-1442. Epub 2016 Jun 30.

PMID:
27365528
17.

CCR1 antagonism attenuates T cell trafficking to omentum and liver in obesity-associated cancer.

Conroy MJ, Galvin KC, Kavanagh ME, Mongan AM, Doyle SL, Gilmartin N, O'Farrelly C, Reynolds JV, Lysaght J.

Immunol Cell Biol. 2016 Jul;94(6):531-7. doi: 10.1038/icb.2016.26. Epub 2016 Apr 5.

PMID:
27046081
18.

Using Confocal Microscopy to Investigate Intracellular Trafficking of Toll-Like Receptors.

Husebye H, Doyle SL.

Methods Mol Biol. 2016;1390:65-77. doi: 10.1007/978-1-4939-3335-8_4.

PMID:
26803622
19.

Author Response: The Role of IL-18 in the Treatment of AMD.

Doyle SL, López FJ, Humphries P, Adamson P, Campbell M.

Invest Ophthalmol Vis Sci. 2015 Dec;56(13):8237-8. doi: 10.1167/iovs.15-18714. No abstract available.

PMID:
26720477
20.

IL-18 Immunotherapy for Neovascular AMD: Tolerability and Efficacy in Nonhuman Primates.

Doyle SL, López FJ, Celkova L, Brennan K, Mulfaul K, Ozaki E, Kenna PF, Kurali E, Hudson N, Doggett T, Ferguson TA, Humphries P, Adamson P, Campbell M.

Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5424-30. doi: 10.1167/iovs.15-17264.

PMID:
26284546
21.

NLRP3 Inflammasome and Pathobiology in AMD.

Celkova L, Doyle SL, Campbell M.

J Clin Med. 2015 Jan 14;4(1):172-92. doi: 10.3390/jcm4010172. Review.

22.

Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectives.

Ozaki E, Campbell M, Doyle SL.

J Inflamm Res. 2015 Jan 16;8:15-27. doi: 10.2147/JIR.S51250. eCollection 2015. Review.

23.

Interleukin-18 bioactivity and dose: data interpretation at a crossroads.

Doyle SL, Adamson P, López FJ, Humphries P, Campbell M.

Invest Ophthalmol Vis Sci. 2014 Dec 23;55(12):8349-50. doi: 10.1167/iovs.14-15786. No abstract available.

PMID:
25538010
24.

Reply to IL-18 is not therapeutic for neovascular age-related macular degeneration.

Doyle SL, Adamson P, López FJ, Humphries P, Campbell M.

Nat Med. 2014 Dec;20(12):1376-7. doi: 10.1038/nm.3741. No abstract available.

PMID:
25473915
25.

TRAM is required for TLR2 endosomal signaling to type I IFN induction.

Stack J, Doyle SL, Connolly DJ, Reinert LS, O'Keeffe KM, McLoughlin RM, Paludan SR, Bowie AG.

J Immunol. 2014 Dec 15;193(12):6090-102. doi: 10.4049/jimmunol.1401605. Epub 2014 Nov 10.

26.

IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration.

Doyle SL, Ozaki E, Brennan K, Humphries MM, Mulfaul K, Keaney J, Kenna PF, Maminishkis A, Kiang AS, Saunders SP, Hams E, Lavelle EC, Gardiner C, Fallon PG, Adamson P, Humphries P, Campbell M.

Sci Transl Med. 2014 Apr 2;6(230):230ra44. doi: 10.1126/scitranslmed.3007616.

27.

An overview of the involvement of interleukin-18 in degenerative retinopathies.

Campbell M, Doyle SL, Ozaki E, Kenna PF, Kiang AS, Humphries MM, Humphries P.

Adv Exp Med Biol. 2014;801:409-15. doi: 10.1007/978-1-4614-3209-8_52. Review.

PMID:
24664725
28.

Inflammation in age-related macular degeneration.

Ozaki E, Campbell M, Kiang AS, Humphries M, Doyle SL, Humphries P.

Adv Exp Med Biol. 2014;801:229-35. doi: 10.1007/978-1-4614-3209-8_30. Review.

PMID:
24664703
29.

Plasmonics-enhanced and optically modulated delivery of gold nanostars into brain tumor.

Yuan H, Wilson CM, Xia J, Doyle SL, Li S, Fales AM, Liu Y, Ozaki E, Mulfaul K, Hanna G, Palmer GM, Wang LV, Grant GA, Vo-Dinh T.

Nanoscale. 2014 Apr 21;6(8):4078-82. doi: 10.1039/c3nr06770j. Epub 2014 Mar 11.

30.

The role of obesity in gastrointestinal cancer: evidence and opinion.

Donohoe CL, O'Farrell NJ, Doyle SL, Reynolds JV.

Therap Adv Gastroenterol. 2014 Jan;7(1):38-50. doi: 10.1177/1756283X13501786. Review.

31.

Bruton's tyrosine kinase mediates the synergistic signalling between TLR9 and the B cell receptor by regulating calcium and calmodulin.

Kenny EF, Quinn SR, Doyle SL, Vink PM, van Eenennaam H, O'Neill LA.

PLoS One. 2013 Aug 14;8(8):e74103. doi: 10.1371/journal.pone.0074103. eCollection 2013.

32.

Nuclear factor κB2 p52 protein has a role in antiviral immunity through IκB kinase epsilon-dependent induction of Sp1 protein and interleukin 15.

Doyle SL, Shirey KA, McGettrick AF, Kenny EF, Carpenter S, Caffrey BE, Gargan S, Quinn SR, Caamaño JH, Moynagh P, Vogel SN, O'Neill LA.

J Biol Chem. 2013 Aug 30;288(35):25066-75. doi: 10.1074/jbc.M113.469122. Epub 2013 Jul 19.

33.

An eye on the future of inflammasomes and drug development in AMD.

Campbell M, Doyle SL.

J Mol Med (Berl). 2013 Sep;91(9):1059-70. doi: 10.1007/s00109-013-1050-0. Epub 2013 May 10. Review.

PMID:
23661041
34.

Establishing computed tomography-defined visceral fat area thresholds for use in obesity-related cancer research.

Doyle SL, Bennett AM, Donohoe CL, Mongan AM, Howard JM, Lithander FE, Pidgeon GP, Reynolds JV, Lysaght J.

Nutr Res. 2013 Mar;33(3):171-9. doi: 10.1016/j.nutres.2012.12.007. Epub 2013 Jan 30.

PMID:
23507222
35.

Conjugated linoleic acid suppresses IRF3 activation via modulation of CD14.

Dowling JK, McCoy CE, Doyle SL, BenLarbi N, Canavan M, O'Neill LA, Loscher CE.

J Nutr Biochem. 2013 May;24(5):920-8. doi: 10.1016/j.jnutbio.2012.06.010. Epub 2012 Aug 15.

PMID:
22901688
36.

NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components.

Doyle SL, Campbell M, Ozaki E, Salomon RG, Mori A, Kenna PF, Farrar GJ, Kiang AS, Humphries MM, Lavelle EC, O'Neill LA, Hollyfield JG, Humphries P.

Nat Med. 2012 May;18(5):791-8. doi: 10.1038/nm.2717.

37.

The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation.

Doyle SL, Husebye H, Connolly DJ, Espevik T, O'Neill LA, McGettrick AF.

Nat Commun. 2012 Feb 28;3:707. doi: 10.1038/ncomms1706.

PMID:
22426228
38.

Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma.

Donohoe CL, Doyle SL, McGarrigle S, Cathcart MC, Daly E, O'Grady A, Lysaght J, Pidgeon GP, Reynolds JV.

Br J Surg. 2012 Mar;99(3):387-96. doi: 10.1002/bjs.8658. Epub 2012 Jan 12.

PMID:
22241325
39.

Outcomes of implementing rapid triage in the pediatric emergency department.

Doyle SL, Kingsnorth J, Guzzetta CE, Jahnke SA, McKenna JC, Brown K.

J Emerg Nurs. 2012 Jan;38(1):30-5. doi: 10.1016/j.jen.2010.08.013. Epub 2011 Jan 22.

PMID:
22226134
40.

IGF-1 and its receptor in esophageal cancer: association with adenocarcinoma and visceral obesity.

Doyle SL, Donohoe CL, Finn SP, Howard JM, Lithander FE, Reynolds JV, Pidgeon GP, Lysaght J.

Am J Gastroenterol. 2012 Feb;107(2):196-204. doi: 10.1038/ajg.2011.417. Epub 2011 Dec 6.

PMID:
22146489
41.

Visceral obesity, metabolic syndrome, insulin resistance and cancer.

Doyle SL, Donohoe CL, Lysaght J, Reynolds JV.

Proc Nutr Soc. 2012 Feb;71(1):181-9. doi: 10.1017/S002966511100320X. Epub 2011 Nov 3.

PMID:
22051112
42.

Visceral adiposity, insulin resistance and cancer risk.

Donohoe CL, Doyle SL, Reynolds JV.

Diabetol Metab Syndr. 2011 Jun 22;3:12. doi: 10.1186/1758-5996-3-12.

43.

Diet, obesity and cancer.

Reynolds JV, Donohoe CL, Doyle SL.

Ir J Med Sci. 2011 Jun;180(2):521-7. doi: 10.1007/s11845-010-0653-5. Epub 2010 Dec 21. Review.

PMID:
21174166
44.

IL-10 inhibits miR-155 induction by toll-like receptors.

McCoy CE, Sheedy FJ, Qualls JE, Doyle SL, Quinn SR, Murray PJ, O'Neill LA.

J Biol Chem. 2010 Jul 2;285(27):20492-8. doi: 10.1074/jbc.M110.102111. Epub 2010 Apr 30.

45.

Obesity and post-operative complications in patients undergoing non-bariatric surgery.

Doyle SL, Lysaght J, Reynolds JV.

Obes Rev. 2010 Dec;11(12):875-86. doi: 10.1111/j.1467-789X.2009.00700.x. Review.

PMID:
20025695
46.

Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer.

O'Neill LA, Bryant CE, Doyle SL.

Pharmacol Rev. 2009 Jun;61(2):177-97. doi: 10.1124/pr.109.001073. Epub 2009 May 27. Review.

47.

TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway.

Palsson-McDermott EM, Doyle SL, McGettrick AF, Hardy M, Husebye H, Banahan K, Gong M, Golenbock D, Espevik T, O'Neill LA.

Nat Immunol. 2009 Jun;10(6):579-86. doi: 10.1038/ni.1727. Epub 2009 May 3.

PMID:
19412184
48.

Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase.

Doyle SL, Jefferies CA, Feighery C, O'Neill LA.

J Biol Chem. 2007 Dec 21;282(51):36953-60. Epub 2007 Oct 11.

49.

Retrospective cross sectional comparison of initial nonsurgical endodontic treatment and single-tooth implants.

Doyle SL, Hodges JS, Pesun IJ, Law AS, Bowles WR.

Compend Contin Educ Dent. 2007 Jun;28(6):296-301.

PMID:
17682611
50.

Factors affecting outcomes for single-tooth implants and endodontic restorations.

Doyle SL, Hodges JS, Pesun IJ, Baisden MK, Bowles WR.

J Endod. 2007 Apr;33(4):399-402. Epub 2007 Feb 23.

PMID:
17368326

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