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Items: 1 to 50 of 513

1.

Antiprotozoan sesterterpenes and triterpenes isolated from two Ghanaian mushrooms.

Annang F, Pérez-Victoria I, Appiah T, Pérez-Moreno G, Domingo E, Martín J, Mackenzie T, Ruiz-Pérez L, González-Pacanowska D, Genilloud O, Vicente F, Agyare C, Reyes F.

Fitoterapia. 2018 Apr 3. pii: S0367-326X(18)30295-8. doi: 10.1016/j.fitote.2018.03.016. [Epub ahead of print]

PMID:
29625145
2.

Quasispecies and virus.

Domingo E, Perales C.

Eur Biophys J. 2018 Feb 3. doi: 10.1007/s00249-018-1282-6. [Epub ahead of print]

PMID:
29397419
3.

Area at risk and collateral circulation in a first acute myocardial infarction with occluded culprit artery. STEMI vs non-STEMI patients.

Figueras J, Otaegui I, Marti G, Domingo E, Bañeras J, Barrabés JA, Del Blanco BG, Garcia-Dorado D.

Int J Cardiol. 2018 May 15;259:14-19. doi: 10.1016/j.ijcard.2018.01.047. Epub 2018 Jan 31.

PMID:
29361353
4.

Prognostic markers for colorectal cancer: estimating ploidy and stroma.

Danielsen HE, Hveem TS, Domingo E, Pradhan M, Kleppe A, Syvertsen RA, Kostolomov I, Nesheim JA, Askautrud HA, Nesbakken A, Lothe RA, Svindland A, Shepherd N, Novelli M, Johnstone E, Tomlinson I, Kerr R, Kerr DJ.

Ann Oncol. 2018 Mar 1;29(3):616-623. doi: 10.1093/annonc/mdx794.

5.

Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution.

Baker AM, Huang W, Wang XM, Jansen M, Ma XJ, Kim J, Anderson CM, Wu X, Pan L, Su N, Luo Y, Domingo E, Heide T, Sottoriva A, Lewis A, Beggs AD, Wright NA, Rodriguez-Justo M, Park E, Tomlinson I, Graham TA.

Nat Commun. 2017 Dec 8;8(1):1998. doi: 10.1038/s41467-017-02295-5.

6.

Acute Right Ventricular Dysfunction in Intensive Care Unit.

Grignola JC, Domingo E.

Biomed Res Int. 2017;2017:8217105. doi: 10.1155/2017/8217105. Epub 2017 Oct 19. Review.

7.

Pharmacoproteomic characterisation of human colon and rectal cancer.

Frejno M, Zenezini Chiozzi R, Wilhelm M, Koch H, Zheng R, Klaeger S, Ruprecht B, Meng C, Kramer K, Jarzab A, Heinzlmeir S, Johnstone E, Domingo E, Kerr D, Jesinghaus M, Slotta-Huspenina J, Weichert W, Knapp S, Feller SM, Kuster B.

Mol Syst Biol. 2017 Nov 3;13(11):951. doi: 10.15252/msb.20177701.

8.

Short-term exposure to air pollutants increases the risk of ST elevation myocardial infarction and of infarct-related ventricular arrhythmias and mortality.

Bañeras J, Ferreira-González I, Marsal JR, Barrabés JA, Ribera A, Lidón RM, Domingo E, Martí G, García-Dorado D; Codi IAM Registry investigators.

Int J Cardiol. 2018 Jan 1;250:35-42. doi: 10.1016/j.ijcard.2017.10.004. Epub 2017 Oct 5.

PMID:
29056239
9.

Pulmonary vascular disease due to left heart disease: how to achieve a more accurate approach beyond the haemodynamic phenotype.

Grignola JC, Trujillo P, Domingo E.

Eur J Heart Fail. 2017 Sep 26. doi: 10.1002/ejhf.954. [Epub ahead of print] No abstract available.

PMID:
28949088
10.

Extinction of West Nile Virus by Favipiravir through Lethal Mutagenesis.

Escribano-Romero E, Jiménez de Oya N, Domingo E, Saiz JC.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01400-17. doi: 10.1128/AAC.01400-17. Print 2017 Nov.

PMID:
28848019
11.

High sensitivity and negative predictive value of the DETECT algorithm for an early diagnosis of pulmonary arterial hypertension in systemic sclerosis: application in a single center.

Guillén-Del Castillo A, Callejas-Moraga EL, García G, Rodríguez-Palomares JF, Román A, Berastegui C, López-Meseguer M, Domingo E, Fonollosa-Plá V, Simeón-Aznar CP.

Arthritis Res Ther. 2017 Jun 14;19(1):135. doi: 10.1186/s13075-017-1327-8.

12.

Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1.

Sveen A, Johannessen B, Tengs T, Danielsen SA, Eilertsen IA, Lind GE, Berg KCG, Leithe E, Meza-Zepeda LA, Domingo E, Myklebost O, Kerr D, Tomlinson I, Nesbakken A, Skotheim RI, Lothe RA.

Genome Med. 2017 May 24;9(1):46. doi: 10.1186/s13073-017-0434-0.

13.

Pulmonary arterial wall disease in COPD and interstitial lung diseases candidates for lung transplantation.

Domingo E, Grignola JC, Aguilar R, Messeguer ML, Roman A.

Respir Res. 2017 May 6;18(1):85. doi: 10.1186/s12931-017-0568-z.

14.

Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.

de la Higuera I, Ferrer-Orta C, de Ávila AI, Perales C, Sierra M, Singh K, Sarafianos SG, Dehouck Y, Bastolla U, Verdaguer N, Domingo E.

Genome Biol Evol. 2017 May 1;9(5):1212-1228. doi: 10.1093/gbe/evx075.

15.

Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study.

Domingo E, Freeman-Mills L, Rayner E, Glaire M, Briggs S, Vermeulen L, Fessler E, Medema JP, Boot A, Morreau H, van Wezel T, Liefers GJ, Lothe RA, Danielsen SA, Sveen A, Nesbakken A, Zlobec I, Lugli A, Koelzer VH, Berger MD, Castellví-Bel S, Muñoz J; Epicolon consortium, de Bruyn M, Nijman HW, Novelli M, Lawson K, Oukrif D, Frangou E, Dutton P, Tejpar S, Delorenzi M, Kerr R, Kerr D, Tomlinson I, Church DN.

Lancet Gastroenterol Hepatol. 2016 Nov;1(3):207-216. doi: 10.1016/S2468-1253(16)30014-0. Epub 2016 Jul 20.

PMID:
28404093
16.

Favipiravir can evoke lethal mutagenesis and extinction of foot-and-mouth disease virus.

de Avila AI, Moreno E, Perales C, Domingo E.

Virus Res. 2017 Apr 2;233:105-112. doi: 10.1016/j.virusres.2017.03.014. Epub 2017 Mar 18.

PMID:
28322918
17.

Internal Disequilibria and Phenotypic Diversification during Replication of Hepatitis C Virus in a Noncoevolving Cellular Environment.

Moreno E, Gallego I, Gregori J, Lucía-Sanz A, Soria ME, Castro V, Beach NM, Manrubia S, Quer J, Esteban JI, Rice CM, Gómez J, Gastaminza P, Domingo E, Perales C.

J Virol. 2017 Apr 28;91(10). pii: e02505-16. doi: 10.1128/JVI.02505-16. Print 2017 May 15.

18.

BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer.

López-García C, Sansregret L, Domingo E, McGranahan N, Hobor S, Birkbak NJ, Horswell S, Grönroos E, Favero F, Rowan AJ, Matthews N, Begum S, Phillimore B, Burrell R, Oukrif D, Spencer-Dene B, Kovac M, Stamp G, Stewart A, Danielsen H, Novelli M, Tomlinson I, Swanton C.

Cancer Cell. 2017 Jan 9;31(1):79-93. doi: 10.1016/j.ccell.2016.11.001.

19.

Deep sequencing in the management of hepatitis virus infections.

Quer J, Rodríguez-Frias F, Gregori J, Tabernero D, Soria ME, García-Cehic D, Homs M, Bosch A, Pintó RM, Esteban JI, Domingo E, Perales C.

Virus Res. 2017 Jul 15;239:115-125. doi: 10.1016/j.virusres.2016.12.020. Epub 2016 Dec 28. Review.

PMID:
28040474
20.

An Efficient Microarray-Based Genotyping Platform for the Identification of Drug-Resistance Mutations in Majority and Minority Subpopulations of HIV-1 Quasispecies.

Martín V, Perales C, Fernández-Algar M, Dos Santos HG, Garrido P, Pernas M, Parro V, Moreno M, García-Pérez J, Alcamí J, Torán JL, Abia D, Domingo E, Briones C.

PLoS One. 2016 Dec 13;11(12):e0166902. doi: 10.1371/journal.pone.0166902. eCollection 2016.

21.

Is sidedness prognostically important across all stages of colorectal cancer?

Kerr DJ, Domingo E, Kerr R.

Lancet Oncol. 2016 Nov;17(11):1480-1482. doi: 10.1016/S1470-2045(16)30431-4. No abstract available. Erratum in: Lancet Oncol. 2016 Dec;17 (12 ):e519.

PMID:
27819229
22.

MDN-0170, a New Napyradiomycin from Streptomyces sp. Strain CA-271078.

Lacret R, Pérez-Victoria I, Oves-Costales D, de la Cruz M, Domingo E, Martín J, Díaz C, Vicente F, Genilloud O, Reyes F.

Mar Drugs. 2016 Oct 18;14(10). pii: E188.

23.

Lethal Mutagenesis of Hepatitis C Virus Induced by Favipiravir.

de Ávila AI, Gallego I, Soria ME, Gregori J, Quer J, Esteban JI, Rice CM, Domingo E, Perales C.

PLoS One. 2016 Oct 18;11(10):e0164691. doi: 10.1371/journal.pone.0164691. eCollection 2016.

24.

Adjuvant capecitabine plus bevacizumab versus capecitabine alone in patients with colorectal cancer (QUASAR 2): an open-label, randomised phase 3 trial.

Kerr RS, Love S, Segelov E, Johnstone E, Falcon B, Hewett P, Weaver A, Church D, Scudder C, Pearson S, Julier P, Pezzella F, Tomlinson I, Domingo E, Kerr DJ.

Lancet Oncol. 2016 Nov;17(11):1543-1557. doi: 10.1016/S1470-2045(16)30172-3. Epub 2016 Sep 19.

PMID:
27660192
25.

Correction for Quer at al., High-Resolution Hepatitis C Virus Subtyping Using NS5B Deep Sequencing and Phylogeny, an Alternative to Current Methods.

Quer J, Gregori J, Rodríguez-Frias F, Buti M, Madejon A, Perez-Del-Pulgar S, Garcia-Cehic D, Casillas R, Blasi M, Homs M, Tabernero D, Alvarez-Tejado M, Muñoz JM, Cubero M, Caballero A, delCampo JA, Domingo E, Belmonte I, Nieto L, Lens S, Muñoz-de-Rueda P, Sanz-Cameno P, Sauleda S, Bes M, Gomez J, Briones C, Perales C, Sheldon J, Castells L, Viladomiu L, Salmeron J, Ruiz-Extremera A, Quiles-Pérez R, Moreno-Otero R, López-Rodríguez R, Allende H, Romero-Gómez M, Guardia J, Esteban R, Garcia-Samaniego J, Forns X, Esteban JI.

J Clin Microbiol. 2016 Jul;54(7):1933. doi: 10.1128/JCM.01007-16. No abstract available.

26.

Quasispecies theory has come of age, and regular updates of the concept of mutation. Introduction.

Domingo E, Schuster P.

Curr Top Microbiol Immunol. 2016;392:ix-xi. No abstract available.

PMID:
27222902
27.

Involvement of a joker mutation in a polymerase-independent lethal mutagenesis escape mechanism.

Agudo R, de la Higuera I, Arias A, Grande-Pérez A, Domingo E.

Virology. 2016 Jul;494:257-66. doi: 10.1016/j.virol.2016.04.023. Epub 2016 Apr 29.

28.

Barrier-Independent, Fitness-Associated Differences in Sofosbuvir Efficacy against Hepatitis C Virus.

Gallego I, Sheldon J, Moreno E, Gregori J, Quer J, Esteban JI, Rice CM, Domingo E, Perales C.

Antimicrob Agents Chemother. 2016 May 23;60(6):3786-93. doi: 10.1128/AAC.00581-16. Print 2016 Jun.

29.

Viral quasispecies complexity measures.

Gregori J, Perales C, Rodriguez-Frias F, Esteban JI, Quer J, Domingo E.

Virology. 2016 Jun;493:227-37. doi: 10.1016/j.virol.2016.03.017. Epub 2016 Apr 6. Review.

30.

Hepatitis C Virus RNA-Dependent RNA Polymerase Interacts with the Akt/PKB Kinase and Induces Its Subcellular Relocalization.

Valero ML, Sabariegos R, Cimas FJ, Perales C, Domingo E, Sánchez-Prieto R, Mas A.

Antimicrob Agents Chemother. 2016 May 23;60(6):3540-50. doi: 10.1128/AAC.03019-15. Print 2016 Jun.

31.

Resistance of Hepatitis C Virus to Inhibitors: Complexity and Clinical Implications.

Perales C, Quer J, Gregori J, Esteban JI, Domingo E.

Viruses. 2015 Nov 6;7(11):5746-66. doi: 10.3390/v7112902. Review.

32.

Quasispecies dynamics in hepatitis C liver transplant recipients receiving grafts from hepatitis C virus infected donors.

Pérez-del-Pulgar S, Gregori J, Rodríguez-Frías F, González P, García-Cehic D, Ramírez S, Casillas R, Domingo E, Esteban JI, Forns X, Quer J.

J Gen Virol. 2015 Dec;96(12):3493-8.

PMID:
26395289
33.

What Is a Quasispecies? Historical Origins and Current Scope.

Domingo E, Schuster P.

Curr Top Microbiol Immunol. 2016;392:1-22. doi: 10.1007/82_2015_453. Review.

PMID:
26318138
34.

Antiviral Strategies Based on Lethal Mutagenesis and Error Threshold.

Perales C, Domingo E.

Curr Top Microbiol Immunol. 2016;392:323-39. doi: 10.1007/82_2015_459. Review.

PMID:
26294225
35.

Clonality and intracellular polyploidy in virus evolution and pathogenesis.

Perales C, Moreno E, Domingo E.

Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):8887-92. doi: 10.1073/pnas.1501715112. Epub 2015 Jul 20.

36.

Methylation changes in the TFAP2E promoter region are associated with BRAF mutation and poorer overall & disease free survival in colorectal cancer.

Beggs AD, Dilworth MP, Domingo E, Midgley R, Kerr D, Tomlinson IP, Middleton GW.

Oncoscience. 2015 Mar 23;2(5):508-16. eCollection 2015.

37.

Percutaneous interventions in Fontan circulation.

Franco E, Domingo EJB, Del Val VA, Silva LGG, Del Cerro Marín MJ, Ruiz AF, Villagrá F, Aguado FG.

Int J Cardiol Heart Vasc. 2015 Jun 23;8:138-146. doi: 10.1016/j.ijcha.2015.06.008. eCollection 2015 Sep 1.

38.

The emerging role of the contractile and vascular reserves in pulmonary arterial hypertension.

Grignola JC, Domingo E.

Eur Respir J. 2015 Jun;45(6):1756-8. doi: 10.1183/09031936.00023015. No abstract available.

39.

Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.

Ferrer-Orta C, de la Higuera I, Caridi F, Sánchez-Aparicio MT, Moreno E, Perales C, Singh K, Sarafianos SG, Sobrino F, Domingo E, Verdaguer N.

J Virol. 2015 Jul;89(13):6848-59. doi: 10.1128/JVI.03283-14. Epub 2015 Apr 22.

40.

Viral quasispecies.

Andino R, Domingo E.

Virology. 2015 May;479-480:46-51. doi: 10.1016/j.virol.2015.03.022. Epub 2015 Mar 29. Review.

41.

Hepatitis C virus-mediated Aurora B kinase inhibition modulates inflammatory pathway and viral infectivity.

Madejón A, Sheldon J, Francisco-Recuero I, Perales C, Domínguez-Beato M, Lasa M, Sánchez-Perez I, Muntané J, Domingo E, García-Samaniego J, Sánchez-Pacheco A.

J Hepatol. 2015 Aug;63(2):312-9. doi: 10.1016/j.jhep.2015.02.036. Epub 2015 Feb 27.

PMID:
25733156
42.

High-resolution hepatitis C virus subtyping using NS5B deep sequencing and phylogeny, an alternative to current methods.

Quer J, Gregori J, Rodríguez-Frias F, Buti M, Madejon A, Perez-del-Pulgar S, Garcia-Cehic D, Casillas R, Blasi M, Homs M, Tabernero D, Alvarez-Tejado M, Muñoz JM, Cubero M, Caballero A, del Campo JA, Domingo E, Belmonte I, Nieto L, Lens S, Muñoz-de-Rueda P, Sanz-Cameno P, Sauleda S, Bes M, Gomez J, Briones C, Perales C, Sheldon J, Castells L, Viladomiu L, Salmeron J, Ruiz-Extremera A, Quiles-Pérez R, Moreno-Otero R, López-Rodríguez R, Allende H, Romero-Gómez M, Guardia J, Esteban R, Garcia-Samaniego J, Forns X, Esteban JI.

J Clin Microbiol. 2015 Jan;53(1):219-26. doi: 10.1128/JCM.02093-14. Epub 2014 Nov 5. Erratum in: J Clin Microbiol. 2016 Jul;54(7):1933.

43.

Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance.

Hamdollah Zadeh MA, Amin EM, Hoareau-Aveilla C, Domingo E, Symonds KE, Ye X, Heesom KJ, Salmon A, D'Silva O, Betteridge KB, Williams AC, Kerr DJ, Salmon AH, Oltean S, Midgley RS, Ladomery MR, Harper SJ, Varey AH, Bates DO.

Mol Oncol. 2015 Jan;9(1):167-78. doi: 10.1016/j.molonc.2014.07.017. Epub 2014 Aug 20.

44.

[Acute stent thrombosis and reverse transient left ventricular dilatation after performing a single-photon emission computed tomography myocardial perfusion].

Miranda B, Pizzi MN, Aguadé-Bruix S, Domingo E, Candell-Riera J.

Rev Esp Med Nucl Imagen Mol. 2015 Mar-Apr;34(2):107-10. doi: 10.1016/j.remn.2014.07.005. Epub 2014 Aug 14. Spanish.

45.

Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virus.

Sheldon J, Beach NM, Moreno E, Gallego I, Piñeiro D, Martínez-Salas E, Gregori J, Quer J, Esteban JI, Rice CM, Domingo E, Perales C.

J Virol. 2014 Oct;88(20):12098-111. doi: 10.1128/JVI.01860-14. Epub 2014 Aug 13.

46.

[Treatment of pulmonary arterial hypertension].

Roman A, López-Meseguer M, Domingo E.

Med Clin (Barc). 2015 Jun 22;144(12):566-70. doi: 10.1016/j.medcli.2014.03.033. Epub 2014 Jul 26. Review. Spanish.

PMID:
25070518
47.

The unfolded protein response and the phosphorylations of activating transcription factor 2 in the trans-activation of il23a promoter produced by β-glucans.

Rodríguez M, Domingo E, Alonso S, Frade JG, Eiros J, Crespo MS, Fernández N.

J Biol Chem. 2014 Aug 15;289(33):22942-57. doi: 10.1074/jbc.M113.522656. Epub 2014 Jun 30.

48.

Molecular basis of interferon resistance in hepatitis C virus.

Perales C, Beach NM, Sheldon J, Domingo E.

Curr Opin Virol. 2014 Oct;8:38-44. doi: 10.1016/j.coviro.2014.05.003. Epub 2014 Jun 23. Review.

PMID:
24968186
49.

'Toxgnostics': an unmet need in cancer medicine.

Church D, Kerr R, Domingo E, Rosmarin D, Palles C, Maskell K, Tomlinson I, Kerr D.

Nat Rev Cancer. 2014 Jun;14(6):440-5. doi: 10.1038/nrc3729. Epub 2014 May 15. Review.

PMID:
24827503
50.

Impairment of pulmonary vascular reserve and right ventricular systolic reserve in pulmonary arterial hypertension.

Domingo E, Grignola JC, Aguilar R, Arredondo C, Bouteldja N, Messeguer ML, Roman A.

BMC Pulm Med. 2014 Apr 24;14:69. doi: 10.1186/1471-2466-14-69.

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