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Effectiveness of text message based, diabetes self management support programme (SMS4BG): two arm, parallel randomised controlled trial.

Dobson R, Whittaker R, Jiang Y, Maddison R, Shepherd M, McNamara C, Cutfield R, Khanolkar M, Murphy R.

BMJ. 2018 May 17;361:k1959. doi: 10.1136/bmj.k1959.


Aurora kinase A (AURKA) interaction with Wnt and Ras-MAPK signalling pathways in colorectal cancer.

Jacobsen A, Bosch LJW, Martens-de Kemp SR, Carvalho B, Sillars-Hardebol AH, Dobson RJ, de Rinaldis E, Meijer GA, Abeln S, Heringa J, Fijneman RJA, Feenstra KA.

Sci Rep. 2018 May 14;8(1):7522. doi: 10.1038/s41598-018-24982-z.


Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site.

Wahlgren WY, Dunevall E, North RA, Paz A, Scalise M, Bisignano P, Bengtsson-Palme J, Goyal P, Claesson E, Caing-Carlsson R, Andersson R, Beis K, Nilsson UJ, Farewell A, Pochini L, Indiveri C, Grabe M, Dobson RCJ, Abramson J, Ramaswamy S, Friemann R.

Nat Commun. 2018 May 1;9(1):1753. doi: 10.1038/s41467-018-04045-7.


Cancer and the heart.

Dobson R, Wright DJ.

Br J Gen Pract. 2018 May;68(670):220-221. doi: 10.3399/bjgp18X695861. No abstract available.


A Three-Ring Circus: Metabolism of the Three Proteogenic Aromatic Amino Acids and Their Role in the Health of Plants and Animals.

Parthasarathy A, Cross PJ, Dobson RCJ, Adams LE, Savka MA, Hudson AO.

Front Mol Biosci. 2018 Apr 6;5:29. doi: 10.3389/fmolb.2018.00029. eCollection 2018. Review.


The self-association and thermal denaturation of caprine and bovine β-lactoglobulin.

Crowther JM, Allison JR, Smolenski GA, Hodgkinson AJ, Jameson GB, Dobson RCJ.

Eur Biophys J. 2018 Apr 16. doi: 10.1007/s00249-018-1300-8. [Epub ahead of print]


Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables.

Iniesta R, Hodgson K, Stahl D, Malki K, Maier W, Rietschel M, Mors O, Hauser J, Henigsberg N, Dernovsek MZ, Souery D, Dobson R, Aitchison KJ, Farmer A, McGuffin P, Lewis CM, Uher R.

Sci Rep. 2018 Apr 3;8(1):5530. doi: 10.1038/s41598-018-23584-z.


Assessing the implementation processes of a large-scale, multi-year quality improvement initiative: survey of health care providers.

Goodridge D, Rana M, Harrison EL, Rotter T, Dobson R, Groot G, Udod S, Lloyd J.

BMC Health Serv Res. 2018 Apr 3;18(1):237. doi: 10.1186/s12913-018-3045-6.


A Blood Test for Alzheimer's Disease: Progress, Challenges, and Recommendations.

Kiddle SJ, Voyle N, Dobson RJB.

J Alzheimers Dis. 2018 Mar 29. doi: 10.3233/JAD-179904. [Epub ahead of print]


How to improve the standardization and the diagnostic performance of the fecal egg count reduction test?

Levecke B, Kaplan RM, Thamsborg SM, Torgerson PR, Vercruysse J, Dobson RJ.

Vet Parasitol. 2018 Apr 15;253:71-78. doi: 10.1016/j.vetpar.2018.02.004. Epub 2018 Feb 9.


A Decade of Blood Biomarkers for Alzheimer's Disease Research: An Evolving Field, Improving Study Designs, and the Challenge of Replication.

Shi L, Baird AL, Westwood S, Hye A, Dobson R, Thambisetty M, Lovestone S.

J Alzheimers Dis. 2018;62(3):1181-1198. doi: 10.3233/JAD-170531.


Author Correction: Knowledge graph prediction of unknown adverse drug reactions and validation in electronic health records.

Bean DM, Wu H, Iqbal E, Dzahini O, Ibrahim ZM, Broadbent M, Stewart R, Dobson RJB.

Sci Rep. 2018 Mar 6;8(1):4284. doi: 10.1038/s41598-018-22521-4.


Potential for Bacteriophage Endolysins to Supplement or Replace Antibiotics in Food Production and Clinical Care.

Love MJ, Bhandari D, Dobson RCJ, Billington C.

Antibiotics (Basel). 2018 Feb 27;7(1). pii: E17. doi: 10.3390/antibiotics7010017. Review.


Big data from electronic health records for early and late translational cardiovascular research: challenges and potential.

Hemingway H, Asselbergs FW, Danesh J, Dobson R, Maniadakis N, Maggioni A, van Thiel GJM, Cronin M, Brobert G, Vardas P, Anker SD, Grobbee DE, Denaxas S; Innovative Medicines Initiative 2nd programme, Big Data for Better Outcomes, BigData@Heart Consortium of 20 academic and industry partners including ESC.

Eur Heart J. 2018 Apr 21;39(16):1481-1495. doi: 10.1093/eurheartj/ehx487.


SemEHR: A general-purpose semantic search system to surface semantic data from clinical notes for tailored care, trial recruitment, and clinical research.

Wu H, Toti G, Morley KI, Ibrahim ZM, Folarin A, Jackson R, Kartoglu I, Agrawal A, Stringer C, Gale D, Gorrell G, Roberts A, Broadbent M, Stewart R, Dobson RJB.

J Am Med Inform Assoc. 2018 May 1;25(5):530-537. doi: 10.1093/jamia/ocx160.


"Just a spoonful of sugar...": import of sialic acid across bacterial cell membranes.

North RA, Horne CR, Davies JS, Remus DM, Muscroft-Taylor AC, Goyal P, Wahlgren WY, Ramaswamy S, Friemann R, Dobson RCJ.

Biophys Rev. 2018 Apr;10(2):219-227. doi: 10.1007/s12551-017-0343-x. Epub 2017 Dec 8. Review.


Knowledge graph prediction of unknown adverse drug reactions and validation in electronic health records.

Bean DM, Wu H, Iqbal E, Dzahini O, Ibrahim ZM, Broadbent M, Stewart R, Dobson RJB.

Sci Rep. 2017 Nov 27;7(1):16416. doi: 10.1038/s41598-017-16674-x. Erratum in: Sci Rep. 2018 Mar 6;8(1):4284.


ADEPt, a semantically-enriched pipeline for extracting adverse drug events from free-text electronic health records.

Iqbal E, Mallah R, Rhodes D, Wu H, Romero A, Chang N, Dzahini O, Pandey C, Broadbent M, Stewart R, Dobson RJB, Ibrahim ZM.

PLoS One. 2017 Nov 9;12(11):e0187121. doi: 10.1371/journal.pone.0187121. eCollection 2017.


Effects of Beneficial Mutations in pykF Gene Vary over Time and across Replicate Populations in a Long-Term Experiment with Bacteria.

Peng F, Widmann S, Wünsche A, Duan K, Donovan KA, Dobson RCJ, Lenski RE, Cooper TF.

Mol Biol Evol. 2018 Jan 1;35(1):202-210. doi: 10.1093/molbev/msx279.


Network analysis of patient flow in two UK acute care hospitals identifies key sub-networks for A&E performance.

Bean DM, Stringer C, Beeknoo N, Teo J, Dobson RJB.

PLoS One. 2017 Oct 2;12(10):e0185912. doi: 10.1371/journal.pone.0185912. eCollection 2017.


Vitamin D supplementation.

Dobson R, Cock HR, Brex P, Giovannoni G.

Pract Neurol. 2018 Feb;18(1):35-42. doi: 10.1136/practneurol-2017-001720. Epub 2017 Sep 25.


Synthesis and incorporation of an advanced lipid peroxidation end-product building block into collagen mimetic peptides.

Kavianinia I, Yang SH, Kaur H, Harris PWR, Dobson RCJ, Fairbanks AJ, Brimble MA.

Chem Commun (Camb). 2017 Jul 25;53(60):8459-8462. doi: 10.1039/c7cc05025a.


Structural and functional analysis of the GABARAP interaction motif (GIM).

Rogov VV, Stolz A, Ravichandran AC, Rios-Szwed DO, Suzuki H, Kniss A, Löhr F, Wakatsuki S, Dötsch V, Dikic I, Dobson RC, McEwan DG.

EMBO Rep. 2017 Aug;18(8):1382-1396. doi: 10.15252/embr.201643587. Epub 2017 Jun 27.


Trajectories of dementia-related cognitive decline in a large mental health records derived patient cohort.

Baker E, Iqbal E, Johnston C, Broadbent M, Shetty H, Stewart R, Howard R, Newhouse S, Khondoker M, Dobson RJB.

PLoS One. 2017 Jun 7;12(6):e0178562. doi: 10.1371/journal.pone.0178562. eCollection 2017.


Corrigendum: Characterisation of mental health conditions in social media using Informed Deep Learning.

Gkotsis G, Oellrich A, Velupillai S, Liakata M, Hubbard TJP, Dobson RJB, Dutta R.

Sci Rep. 2017 May 16;7:46813. doi: 10.1038/srep46813. No abstract available.


Development of a Culturally Tailored Text Message Maternal Health Program: TextMATCH.

Dobson R, Whittaker R, Bartley H, Connor A, Chen R, Ross M, McCool J.

JMIR Mhealth Uhealth. 2017 Apr 20;5(4):e49. doi: 10.2196/mhealth.7205.


Genetic and environmental risk factors for rheumatoid arthritis in a UK African ancestry population: the GENRA case-control study.

Traylor M, Curtis C, Patel H, Breen G, Hyuck Lee S, Xu X, Newhouse S, Dobson R, Steer S, Cope AP, Markus HS, Lewis CM, Scott IC.

Rheumatology (Oxford). 2017 Aug 1;56(8):1282-1292. doi: 10.1093/rheumatology/kex048.


Brain Transcriptome Sequencing of a Natural Model of Alzheimer's Disease.

Altimiras F, Uszczynska-Ratajczak B, Camara F, Vlasova A, Palumbo E, Newhouse S, Deacon RM, Farias LA, Hurley MJ, Loyola DE, Vásquez RA, Dobson R, Guigó R, Cogram P.

Front Aging Neurosci. 2017 Mar 20;9:64. doi: 10.3389/fnagi.2017.00064. eCollection 2017. No abstract available.


Automated PDF highlighting to support faster curation of literature for Parkinson's and Alzheimer's disease.

Wu H, Oellrich A, Girges C, de Bono B, Hubbard TJ, Dobson RJ.

Database (Oxford). 2017 Jan 1;2017(1). doi: 10.1093/database/bax027.


The Pharmacological Profile of a Novel Highly Potent Bisphosphonate, OX14 (1-Fluoro-2-(Imidazo-[1,2-α]Pyridin-3-yl)-Ethyl-Bisphosphonate).

Lawson MA, Ebetino FH, Mazur A, Chantry AD, Paton-Hough J, Evans HR, Lath D, Tsoumpra MK, Lundy MW, Dobson RL, Quijano M, Kwaasi AA, Dunford JE, Duan X, Triffitt JT, Jeans G, Russell RGG.

J Bone Miner Res. 2017 Sep;32(9):1860-1869. doi: 10.1002/jbmr.3138. Epub 2017 Apr 21.


Characterisation of mental health conditions in social media using Informed Deep Learning.

Gkotsis G, Oellrich A, Velupillai S, Liakata M, Hubbard TJ, Dobson RJ, Dutta R.

Sci Rep. 2017 Mar 22;7:45141. doi: 10.1038/srep45141. Erratum in: Sci Rep. 2017 May 16;7:46813.


Diagnosing and Managing Carcinoid Heart Disease in Patients With Neuroendocrine Tumors: An Expert Statement.

Davar J, Connolly HM, Caplin ME, Pavel M, Zacks J, Bhattacharyya S, Cuthbertson DJ, Dobson R, Grozinsky-Glasberg S, Steeds RP, Dreyfus G, Pellikka PA, Toumpanakis C.

J Am Coll Cardiol. 2017 Mar 14;69(10):1288-1304. doi: 10.1016/j.jacc.2016.12.030. Review.


Dihydrodipicolinate Synthase: Structure, Dynamics, Function, and Evolution.

Grant Pearce F, Hudson AO, Loomes K, Dobson RCJ.

Subcell Biochem. 2017;83:271-289. doi: 10.1007/978-3-319-46503-6_10.


Mitochondrial genes are altered in blood early in Alzheimer's disease.

Lunnon K, Keohane A, Pidsley R, Newhouse S, Riddoch-Contreras J, Thubron EB, Devall M, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Schalkwyk L, Dobson R, Malik AN, Powell J, Lovestone S, Hodges A; AddNeuroMed Consortium.

Neurobiol Aging. 2017 May;53:36-47. doi: 10.1016/j.neurobiolaging.2016.12.029. Epub 2017 Jan 7.


Analysis of diagnoses extracted from electronic health records in a large mental health case register.

Kovalchuk Y, Stewart R, Broadbent M, Hubbard TJ, Dobson RJ.

PLoS One. 2017 Feb 16;12(2):e0171526. doi: 10.1371/journal.pone.0171526. eCollection 2017.


Epstein-Barr-negative MS: a true phenomenon?

Dobson R, Kuhle J, Middeldorp J, Giovannoni G.

Neurol Neuroimmunol Neuroinflamm. 2017 Feb 3;4(2):e318. doi: 10.1212/NXI.0000000000000318. eCollection 2017 Mar. No abstract available.


Natural language processing to extract symptoms of severe mental illness from clinical text: the Clinical Record Interactive Search Comprehensive Data Extraction (CRIS-CODE) project.

Jackson RG, Patel R, Jayatilleke N, Kolliakou A, Ball M, Gorrell G, Roberts A, Dobson RJ, Stewart R.

BMJ Open. 2017 Jan 17;7(1):e012012. doi: 10.1136/bmjopen-2016-012012.


The Prognostic Value of Heart Type Fatty Acid Binding Protein in Patients with Suspected Acute Coronary Syndrome: A Systematic Review.

Jones JD, Chew PG, Dobson R, Wootton A, Ashrafi R, Khand A.

Curr Cardiol Rev. 2017;13(3):189-198. doi: 10.2174/1573403X13666170116121451. Review.


In Reply.

Bailey TG, Cable T, Aziz N, Dobson R, Sprung VS, Low DA, Jones H.

Menopause. 2017 Jan;24(1):118-120. doi: 10.1097/GME.0000000000000819. No abstract available.


Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus.

North RA, Watson AJ, Pearce FG, Muscroft-Taylor AC, Friemann R, Fairbanks AJ, Dobson RC.

FEBS Lett. 2016 Dec;590(23):4414-4428. doi: 10.1002/1873-3468.12462. Epub 2016 Nov 7.


The crystal structure of dihydrodipicolinate reductase from the human-pathogenic bacterium Bartonella henselae strain Houston-1 at 2.3 Å resolution.

Cala AR, Nadeau MT, Abendroth J, Staker BL, Reers AR, Weatherhead AW, Dobson RC, Myler PJ, Hudson AO.

Acta Crystallogr F Struct Biol Commun. 2016 Dec 1;72(Pt 12):885-891. Epub 2016 Nov 25.


Association between Plasma Ceramides and Phosphatidylcholines and Hippocampal Brain Volume in Late Onset Alzheimer's Disease.

Kim M, Nevado-Holgado A, Whiley L, Snowden SG, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Thambisetty M, Dobson RJB, Powell JF, Lupton MK, Simmons A, Velayudhan L, Lovestone S, Proitsi P, Legido-Quigley C.

J Alzheimers Dis. 2017;60(3):809-817. doi: 10.3233/JAD-160645.


Genetic Risk as a Marker of Amyloid-β and Tau Burden in Cerebrospinal Fluid.

Voyle N, Patel H, Folarin A, Newhouse S, Johnston C, Visser PJ, Dobson RJ, Kiddle SJ; EDAR and DESCRIPA study groups and the Alzheimer’s Disease Neuroimaging Initiative.

J Alzheimers Dis. 2017;55(4):1417-1427. doi: 10.3233/JAD-160707.


A Risk Score for Predicting Multiple Sclerosis.

Dobson R, Ramagopalan S, Topping J, Smith P, Solanky B, Schmierer K, Chard D, Giovannoni G.

PLoS One. 2016 Nov 1;11(11):e0164992. doi: 10.1371/journal.pone.0164992. eCollection 2016.


Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis.

Proitsi P, Kim M, Whiley L, Simmons A, Sattlecker M, Velayudhan L, Lupton MK, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Powell JF, Dobson RJ, Legido-Quigley C.

Alzheimers Dement. 2017 Feb;13(2):140-151. doi: 10.1016/j.jalz.2016.08.003. Epub 2016 Sep 28.


The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia.

Blunt MD, Koehrer S, Dobson RC, Larrayoz M, Wilmore S, Hayman A, Parnell J, Smith LD, Davies A, Johnson PWM, Conley PB, Pandey A, Strefford JC, Stevenson FK, Packham G, Forconi F, Coffey GP, Burger JA, Steele AJ.

Clin Cancer Res. 2017 May 1;23(9):2313-2324. doi: 10.1158/1078-0432.CCR-16-1662. Epub 2016 Oct 3.


Avoidance of stochastic RNA interactions can be harnessed to control protein expression levels in bacteria and archaea.

Umu SU, Poole AM, Dobson RC, Gardner PP.

Elife. 2016 Sep 20;5. pii: e13479. doi: 10.7554/eLife.13479.


Complement Biomarkers as Predictors of Disease Progression in Alzheimer's Disease.

Hakobyan S, Harding K, Aiyaz M, Hye A, Dobson R, Baird A, Liu B, Harris CL, Lovestone S, Morgan BP.

J Alzheimers Dis. 2016 Sep 6;54(2):707-16. doi: 10.3233/JAD-160420.


Late gadolinium enhancement and adverse outcomes in a contemporary cohort of adult survivors of tetralogy of Fallot.

Dobson RJ, Mordi I, Danton MH, Walker NL, Walker HA, Tzemos N.

Congenit Heart Dis. 2017 Jan;12(1):58-66. doi: 10.1111/chd.12403. Epub 2016 Aug 24.


Alzheimer's disease: are blood and brain markers related? A systematic review.

Khan AT, Dobson RJ, Sattlecker M, Kiddle SJ.

Ann Clin Transl Neurol. 2016 May 11;3(6):455-62. doi: 10.1002/acn3.313. eCollection 2016 Jun.

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