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Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy.

Katschke KJ Jr, Xi H, Cox C, Truong T, Malato Y, Lee WP, McKenzie B, Arceo R, Tao J, Rangell L, Reichelt M, Diehl L, Elstrott J, Weimer RM, Campagne MVL.

Sci Rep. 2018 May 9;8(1):7348. doi: 10.1038/s41598-018-25557-8.


Portable standoff spectrometer for hazard identification using integrated quantum cascade laser arrays from 6.5 to 11 µm.

Witinski MF, Blanchard R, Pfluegl C, Diehl L, Li B, Krishnamurthy K, Pein BC, Azimi M, Chen P, Ulu G, Vander Rhodes G, Howle CR, Lee L, Clewes RJ, Williams B, Vakhshoori D.

Opt Express. 2018 Apr 30;26(9):12159-12168.


Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases.

Stefanich EG, Rae J, Sukumaran S, Lutman J, Lekkerkerker A, Ouyang W, Wang X, Lee D, Danilenko DM, Diehl L, Loyet KM, Herman A.

Biochem Pharmacol. 2018 Jun;152:224-235. doi: 10.1016/j.bcp.2018.03.031. Epub 2018 Mar 31.


Homozygous KSR1 deletion attenuates morbidity but does not prevent tumor development in a mouse model of RAS-driven pancreatic cancer.

Germino EA, Miller JP, Diehl L, Swanson CJ, Durinck S, Modrusan Z, Miner JH, Shaw AS.

PLoS One. 2018 Mar 29;13(3):e0194998. doi: 10.1371/journal.pone.0194998. eCollection 2018.


Dose-intense chemoimmunotherapy plus radioimmunotherapy in high-risk diffuse large B-cell lymphoma and mantle cell lymphoma: a phase II study.

Hudson KE, Rizzieri D, Thomas SM, LeBlanc TW, Powell Z, Diehl L, Moore JO, DeCastro C, Beaven AW.

Br J Haematol. 2018 Feb 21. doi: 10.1111/bjh.15138. [Epub ahead of print] No abstract available.


Carcinoembryonic antigen-related cell adhesion molecule 1 controls IL-2-dependent regulatory T-cell induction in immune-mediated hepatitis in mice.

Horst AK, Wegscheid C, Schaefers C, Schiller B, Neumann K, Lunemann S, Langeneckert AE, Oldhafer KJ, Weiler-Normann C, Lang KS, Singer BB, Altfeld M, Diehl L, Tiegs G.

Hepatology. 2018 Jan 29. doi: 10.1002/hep.29812. [Epub ahead of print]


Pathology and Pathogenesis of Immune-Mediated Diseases of Animals.

Diehl L, Meyerholz DK, Day MJ, Affolter VK.

Vet Pathol. 2018 Jan;55(1):5-7. doi: 10.1177/0300985817739091. No abstract available.


Targeting myeloid derived suppressor cells with all-trans retinoic acid is highly time-dependent in therapeutic tumor vaccination.

Heine A, Flores C, Gevensleben H, Diehl L, Heikenwalder M, Ringelhan M, Janssen KP, Nitsche U, Garbi N, Brossart P, Knolle PA, Kurts C, Höchst B.

Oncoimmunology. 2017 Jun 16;6(8):e1338995. doi: 10.1080/2162402X.2017.1338995. eCollection 2017.


αEβ7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis.

Lamb CA, Mansfield JC, Tew GW, Gibbons D, Long AK, Irving P, Diehl L, Eastham-Anderson J, Price MB, O'Boyle G, Jones DEJ, O'Byrne S, Hayday A, Keir ME, Egen JG, Kirby JA.

J Crohns Colitis. 2017 May 1;11(5):610-620. doi: 10.1093/ecco-jcc/jjw189.


Ultrasound-assisted extraction of rare-earth elements from carbonatite rocks.

Diehl LO, Gatiboni TL, Mello PA, Muller EI, Duarte FA, Flores EMM.

Ultrason Sonochem. 2018 Jan;40(Pt B):24-29. doi: 10.1016/j.ultsonch.2017.04.012. Epub 2017 Apr 12.


InsuOnline, an Electronic Game for Medical Education on Insulin Therapy: A Randomized Controlled Trial With Primary Care Physicians.

Diehl LA, Souza RM, Gordan PA, Esteves RZ, Coelho IC.

J Med Internet Res. 2017 Mar 9;19(3):e72. doi: 10.2196/jmir.6944.


The Relationship Between Trunk Rotation, Upper Quarter Dynamic Stability, and Pitch Velocity.

Bullock GS, Schmitt AC, Chasse PM, Little BA, Diehl LH, Butler RJ.

J Strength Cond Res. 2018 Jan;32(1):261-266. doi: 10.1519/JSC.0000000000001772.


Evaluation of the biochemical, inflammatory and oxidative profile of obese patients given clinical treatment and bariatric surgery.

Schmatz R, Bitencourt MR, Patias LD, Beck M, da C Alvarez G, Zanini D, Gutierres JM, Diehl LN, Pereira LB, Leal CA, Duarte MF, Schetinger MR, Morsch VM.

Clin Chim Acta. 2017 Feb;465:72-79. doi: 10.1016/j.cca.2016.12.012. Epub 2016 Dec 14.


Surgical Management and Treatment of the Anterior Cruciate Ligament-Deficient Knee with Malalignment.

Crawford MD, Diehl LH, Amendola A.

Clin Sports Med. 2017 Jan;36(1):119-133. doi: 10.1016/j.csm.2016.08.006. Epub 2016 Oct 15. Review.


Neonatal interventions differently affect maternal care quality and have sexually dimorphic developmental effects on corticosterone secretion.

Couto-Pereira NS, Ferreira CF, Lampert C, Arcego DM, Toniazzo AP, Bernardi JR, da Silva DC, Von Poser Toigo E, Diehl LA, Krolow R, Silveira PP, Dalmaz C.

Int J Dev Neurosci. 2016 Dec;55:72-81. doi: 10.1016/j.ijdevneu.2016.10.001. Epub 2016 Oct 4.


Low-dissipation 7.4-µm single-mode quantum cascade lasers without epitaxial regrowth.

Briggs RM, Frez C, Fradet M, Forouhar S, Blanchard R, Diehl L, Pflügl C.

Opt Express. 2016 Jun 27;24(13):14589-95. doi: 10.1364/OE.24.014589.


Injections of Local Anesthetics into the Pharyngeal Region Reduce Trapezius Muscle Tenderness.

Weinschenk S, Hollmann MW, Göllner R, Picardi S, Strowitzki T, Diehl L, Hotz L, Meuser T; Heidelberg University Neural Therapy Education and Research Group (The HUNTER Group).

Forsch Komplementmed. 2016;23(2):111-6. doi: 10.1159/000444665. Epub 2016 Apr 12.


RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury.

Newton K, Dugger DL, Maltzman A, Greve JM, Hedehus M, Martin-McNulty B, Carano RA, Cao TC, van Bruggen N, Bernstein L, Lee WP, Wu X, DeVoss J, Zhang J, Jeet S, Peng I, McKenzie BS, Roose-Girma M, Caplazi P, Diehl L, Webster JD, Vucic D.

Cell Death Differ. 2016 Sep 1;23(9):1565-76. doi: 10.1038/cdd.2016.46. Epub 2016 May 13.


Effect of ultrasonic frequency on separation of water from heavy crude oil emulsion using ultrasonic baths.

Antes FG, Diehl LO, Pereira JS, Guimarães RC, Guarnieri RA, Ferreira BM, Flores EM.

Ultrason Sonochem. 2017 Mar;35(Pt B):541-546. doi: 10.1016/j.ultsonch.2016.03.031. Epub 2016 Apr 1.


Modulation of liver tolerance by conventional and nonconventional antigen-presenting cells and regulatory immune cells.

Horst AK, Neumann K, Diehl L, Tiegs G.

Cell Mol Immunol. 2016 May;13(3):277-92. doi: 10.1038/cmi.2015.112. Epub 2016 Apr 4. Review.


Loss of the LIM-only protein Fhl2 impairs inflammatory reaction and scar formation after cardiac ischemia leading to better hemodynamic performance.

Goltz D, Hittetiya K, Gevensleben H, Kirfel J, Diehl L, Meyer R, Büttner R.

Life Sci. 2016 Apr 15;151:348-358. doi: 10.1016/j.lfs.2016.02.084. Epub 2016 Feb 24.


The induction of human myeloid derived suppressor cells through hepatic stellate cells is dose-dependently inhibited by the tyrosine kinase inhibitors nilotinib, dasatinib and sorafenib, but not sunitinib.

Heine A, Schilling J, Grünwald B, Krüger A, Gevensleben H, Held SA, Garbi N, Kurts C, Brossart P, Knolle P, Diehl L, Höchst B.

Cancer Immunol Immunother. 2016 Mar;65(3):273-82. doi: 10.1007/s00262-015-1790-5. Epub 2016 Jan 19.


IL-33 amplifies an innate immune response in the degenerating retina.

Xi H, Katschke KJ Jr, Li Y, Truong T, Lee WP, Diehl L, Rangell L, Tao J, Arceo R, Eastham-Anderson J, Hackney JA, Iglesias A, Cote-Sierra J, Elstrott J, Weimer RM, van Lookeren Campagne M.

J Exp Med. 2016 Feb 8;213(2):189-207. doi: 10.1084/jem.20150894. Epub 2016 Jan 11.


Peripheral T-cell lymphoma, NOS, and anaplastic large cell lymphoma.

Beaven AW, Diehl LF.

Hematology Am Soc Hematol Educ Program. 2015;2015:550-8. doi: 10.1182/asheducation-2015.1.550.


Effectiveness of a serious game for medical education on insulin therapy: a pilot study.

Diehl LA, Gordan PA, Esteves RZ, Coelho IC.

Arch Endocrinol Metab. 2015 Oct;59(5):470-3. doi: 10.1590/2359-3997000000118.


Association Between Response to Etrolizumab and Expression of Integrin αE and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis.

Tew GW, Hackney JA, Gibbons D, Lamb CA, Luca D, Egen JG, Diehl L, Eastham Anderson J, Vermeire S, Mansfield JC, Feagan BG, Panes J, Baumgart DC, Schreiber S, Dotan I, Sandborn WJ, Kirby JA, Irving PM, De Hertogh G, Van Assche GA, Rutgeerts P, O'Byrne S, Hayday A, Keir ME.

Gastroenterology. 2016 Feb;150(2):477-87.e9. doi: 10.1053/j.gastro.2015.10.041. Epub 2015 Oct 30.


User Assessment of "InsuOnLine," a Game to Fight Clinical Inertia in Diabetes: A Pilot Study.

Diehl LA, de Souza RM, Gordan PA, Esteves RZ, Coelho IC.

Games Health J. 2015 Oct;4(5):335-43. doi: 10.1089/g4h.2014.0111. Epub 2015 Apr 13.


Immunomodulation by splenectomy or by FTY720 protects the heart against ischemia reperfusion injury.

Goltz D, Huss S, Ramadori E, Büttner R, Diehl L, Meyer R.

Clin Exp Pharmacol Physiol. 2015 Nov;42(11):1168-77. doi: 10.1111/1440-1681.12465.


High tuning stability of sampled grating quantum cascade lasers.

Kalchmair S, Blanchard R, Mansuripur TS, de Naurois GM, Pfluegl C, Witinski MF, Diehl L, Capasso F, Loncar M.

Opt Express. 2015 Jun 15;23(12):15734-47. doi: 10.1364/OE.23.015734.


Mouse Models of Rheumatoid Arthritis.

Caplazi P, Baca M, Barck K, Carano RA, DeVoss J, Lee WP, Bolon B, Diehl L.

Vet Pathol. 2015 Sep;52(5):819-26. doi: 10.1177/0300985815588612. Epub 2015 Jun 10. Review.


Image Analysis-Based Approaches for Scoring Mouse Models of Colitis.

Rogers R, Eastham-Anderson J, DeVoss J, Lesch J, Yan D, Xu M, Solon M, Hotzel K, Diehl L, Webster JD.

Vet Pathol. 2016 Jan;53(1):200-10. doi: 10.1177/0300985815579998. Epub 2015 Apr 23.


Low-dose consolidation radiation therapy for early stage unfavorable Hodgkin lymphoma.

Torok JA, Wu Y, Prosnitz LR, Kim GJ, Beaven AW, Diehl LF, Kelsey CR.

Int J Radiat Oncol Biol Phys. 2015 May 1;92(1):54-9. doi: 10.1016/j.ijrobp.2015.02.003.


Differential induction of Ly6G and Ly6C positive myeloid derived suppressor cells in chronic kidney and liver inflammation and fibrosis.

Höchst B, Mikulec J, Baccega T, Metzger C, Welz M, Peusquens J, Tacke F, Knolle P, Kurts C, Diehl L, Ludwig-Portugall I.

PLoS One. 2015 Mar 4;10(3):e0119662. doi: 10.1371/journal.pone.0119662. eCollection 2015.


Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection.

Muñoz M, Eidenschenk C, Ota N, Wong K, Lohmann U, Kühl AA, Wang X, Manzanillo P, Li Y, Rutz S, Zheng Y, Diehl L, Kayagaki N, van Lookeren-Campagne M, Liesenfeld O, Heimesaat M, Ouyang W.

Immunity. 2015 Feb 17;42(2):321-331. doi: 10.1016/j.immuni.2015.01.011. Epub 2015 Feb 10.


Feasibility of low frequency ultrasound for water removal from crude oil emulsions.

Antes FG, Diehl LO, Pereira JS, Guimarães RC, Guarnieri RA, Ferreira BM, Dressler VL, Flores EM.

Ultrason Sonochem. 2015 Jul;25:70-5. doi: 10.1016/j.ultsonch.2015.01.003. Epub 2015 Jan 9.


Simultaneous transcatheter aortic valve replacement and endovascular repair for critical aortic stenosis and large abdominal aortic aneurysm.

Aluko Y, Diehl L, Jacoby R, Chan B, Andrews S, McMillan E, Sharkey K, Shook P, Ntim W, Bolorunduro O, Sossoman LB, Rabb C.

Cardiovasc Revasc Med. 2015 Jun;16(4):254-8. doi: 10.1016/j.carrev.2014.12.001. Epub 2014 Dec 16.


Improving outcomes in advanced DLBCL: systemic approaches and radiotherapy.

Boyle J, Beaven AW, Diehl LF, Prosnitz LR, Kelsey CR.

Oncology (Williston Park). 2014 Dec;28(12):1074-81, 1084.


Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.

Rutz S, Kayagaki N, Phung QT, Eidenschenk C, Noubade R, Wang X, Lesch J, Lu R, Newton K, Huang OW, Cochran AG, Vasser M, Fauber BP, DeVoss J, Webster J, Diehl L, Modrusan Z, Kirkpatrick DS, Lill JR, Ouyang W, Dixit VM.

Nature. 2015 Feb 19;518(7539):417-21. doi: 10.1038/nature13979. Epub 2014 Dec 3.


(18)F-fluorodeoxyglucose-positron emission tomography/computed tomography after one cycle of chemotherapy in patients with diffuse large B-cell lymphoma: results of a Nordic/US intergroup study.

Mylam KJ, Kostakoglu L, Hutchings M, Coleman M, Lamonica D, Czuczman MS, Diehl LF, Nielsen AL, Jensen P, Loft A, Hendel HW, Iyer V, Leppä S, Jyrkkiö S, Holte H, Eriksson M, Gillstrøm D, Hansen PB, Seppänen M, Hjorthaug K, Brown Pde N, Pedersen LM.

Leuk Lymphoma. 2015 Jul;56(7):2005-12. doi: 10.3109/10428194.2014.975800. Epub 2014 Nov 20.


Stress in Neonatal Rats with Different Maternal Care Backgrounds: Monoaminergic and Hormonal Responses.

Henriques TP, Szawka RE, Diehl LA, de Souza MA, Corrêa CN, Aranda BC, Sebben V, Franci CR, Anselmo-Franci JA, Silveira PP, de Almeida RM.

Neurochem Res. 2014 Sep 27. [Epub ahead of print]


Stress in neonatal rats with different maternal care backgrounds: monoaminergic and hormonal responses.

Henriques TP, Szawka RE, Diehl LA, de Souza MA, Corrêa CN, Aranda BC, Sebben V, Franci CR, Anselmo-Franci JA, Silveira PP, de Almeida RM.

Neurochem Res. 2014 Dec;39(12):2351-9. doi: 10.1007/s11064-014-1434-8. Epub 2014 Sep 14.


Dendritic cell CD83 homotypic interactions regulate inflammation and promote mucosal homeostasis.

Bates JM, Flanagan K, Mo L, Ota N, Ding J, Ho S, Liu S, Roose-Girma M, Warming S, Diehl L.

Mucosal Immunol. 2015 Mar;8(2):414-28. doi: 10.1038/mi.2014.79. Epub 2014 Sep 10.


Homeostatic IL-23 receptor signaling limits Th17 response through IL-22-mediated containment of commensal microbiota.

Shih VF, Cox J, Kljavin NM, Dengler HS, Reichelt M, Kumar P, Rangell L, Kolls JK, Diehl L, Ouyang W, Ghilardi N.

Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13942-7. doi: 10.1073/pnas.1323852111. Epub 2014 Sep 8.


Immunological in vivo effects of B7-H1 deficiency.

Bazhin AV, von Ahn K, Maier C, Soltek S, Serba S, Diehl L, Werner J, Karakhanova S.

Immunol Lett. 2014 Dec;162(2 Pt B):273-86. doi: 10.1016/j.imlet.2014.08.013. Epub 2014 Aug 28.


Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics.

Dennis G Jr, Holweg CT, Kummerfeld SK, Choy DF, Setiadi AF, Hackney JA, Haverty PM, Gilbert H, Lin WY, Diehl L, Fischer S, Song A, Musselman D, Klearman M, Gabay C, Kavanaugh A, Endres J, Fox DA, Martin F, Townsend MJ.

Arthritis Res Ther. 2014;16(2):R90. Epub 2014 Apr 30.


Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes.

Wang X, Ota N, Manzanillo P, Kates L, Zavala-Solorio J, Eidenschenk C, Zhang J, Lesch J, Lee WP, Ross J, Diehl L, van Bruggen N, Kolumam G, Ouyang W.

Nature. 2014 Oct 9;514(7521):237-41. doi: 10.1038/nature13564. Epub 2014 Aug 6.


In vivo treatment sensitivity testing with positron emission tomography/computed tomography after one cycle of chemotherapy for Hodgkin lymphoma.

Hutchings M, Kostakoglu L, Zaucha JM, Malkowski B, Biggi A, Danielewicz I, Loft A, Specht L, Lamonica D, Czuczman MS, Nanni C, Zinzani PL, Diehl L, Stern R, Coleman M.

J Clin Oncol. 2014 Sep 1;32(25):2705-11. doi: 10.1200/JCO.2013.53.2838. Epub 2014 Jul 28.


Liver sinusoidal endothelial cell-mediated CD8 T cell priming depends on co-inhibitory signal integration over time.

Kaczmarek J, Homsi Y, van Üüm J, Metzger C, Knolle PA, Kolanus W, Lang T, Diehl L.

PLoS One. 2014 Jun 12;9(6):e99574. doi: 10.1371/journal.pone.0099574. eCollection 2014.


Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial.

Vermeire S, O'Byrne S, Keir M, Williams M, Lu TT, Mansfield JC, Lamb CA, Feagan BG, Panes J, Salas A, Baumgart DC, Schreiber S, Dotan I, Sandborn WJ, Tew GW, Luca D, Tang MT, Diehl L, Eastham-Anderson J, De Hertogh G, Perrier C, Egen JG, Kirby JA, van Assche G, Rutgeerts P.

Lancet. 2014 Jul 26;384(9940):309-18. doi: 10.1016/S0140-6736(14)60661-9. Epub 2014 May 9.


Gaming Habits and Opinions of Brazilian Medical School Faculty and Students: What's Next?

Diehl LA, de Souza RM, Gordan PA, Esteves RZ, Coelho IC.

Games Health J. 2014 Apr;3(2):79-85. doi: 10.1089/g4h.2013.0069. Epub 2014 Mar 12.


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