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Items: 11

1.

Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism.

Kristensen DM, Desdoits-Lethimonier C, Mackey AL, Dalgaard MD, De Masi F, Munkbøl CH, Styrishave B, Antignac JP, Le Bizec B, Platel C, Hay-Schmidt A, Jensen TK, Lesné L, Mazaud-Guittot S, Kristiansen K, Brunak S, Kjaer M, Juul A, Jégou B.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E715-E724. doi: 10.1073/pnas.1715035115. Epub 2018 Jan 8.

2.

Parallel assessment of the effects of bisphenol A and several of its analogs on the adult human testis.

Desdoits-Lethimonier C, Lesné L, Gaudriault P, Zalko D, Antignac JP, Deceuninck Y, Platel C, Dejucq-Rainsford N, Mazaud-Guittot S, Jégou B.

Hum Reprod. 2017 Jul 1;32(7):1465-1473. doi: 10.1093/humrep/dex093.

3.

Ibuprofen results in alterations of human fetal testis development.

Ben Maamar M, Lesné L, Hennig K, Desdoits-Lethimonier C, Kilcoyne KR, Coiffec I, Rolland AD, Chevrier C, Kristensen DM, Lavoué V, Antignac JP, Le Bizec B, Dejucq-Rainsford N, Mitchell RT, Mazaud-Guittot S, Jégou B.

Sci Rep. 2017 Mar 10;7:44184. doi: 10.1038/srep44184.

4.

An investigation of the endocrine-disruptive effects of bisphenol a in human and rat fetal testes.

Ben Maamar M, Lesné L, Desdoits-Lethimonier C, Coiffec I, Lassurguère J, Lavoué V, Deceuninck Y, Antignac JP, Le Bizec B, Perdu E, Zalko D, Pineau C, Chevrier C, Dejucq-Rainsford N, Mazaud-Guittot S, Jégou B.

PLoS One. 2015 Feb 23;10(2):e0117226. doi: 10.1371/journal.pone.0117226. eCollection 2015. Erratum in: PLoS One. 2015;10(5):e0128051.

5.

Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signaling.

Callier P, Calvel P, Matevossian A, Makrythanasis P, Bernard P, Kurosaka H, Vannier A, Thauvin-Robinet C, Borel C, Mazaud-Guittot S, Rolland A, Desdoits-Lethimonier C, Guipponi M, Zimmermann C, Stévant I, Kuhne F, Conne B, Santoni F, Lambert S, Huet F, Mugneret F, Jaruzelska J, Faivre L, Wilhelm D, Jégou B, Trainor PA, Resh MD, Antonarakis SE, Nef S.

PLoS Genet. 2014 May 1;10(5):e1004340. doi: 10.1371/journal.pgen.1004340. eCollection 2014 May.

6.

Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent.

Mazaud-Guittot S, Nicolas Nicolaz C, Desdoits-Lethimonier C, Coiffec I, Ben Maamar M, Balaguer P, Kristensen DM, Chevrier C, Lavoué V, Poulain P, Dejucq-Rainsford N, Jégou B.

J Clin Endocrinol Metab. 2013 Nov;98(11):E1757-67. doi: 10.1210/jc.2013-2531. Epub 2013 Sep 12.

PMID:
24030937
7.

Paracetamol, aspirin and indomethacin display endocrine disrupting properties in the adult human testis in vitro.

Albert O, Desdoits-Lethimonier C, Lesné L, Legrand A, Guillé F, Bensalah K, Dejucq-Rainsford N, Jégou B.

Hum Reprod. 2013 Jul;28(7):1890-8. doi: 10.1093/humrep/det112. Epub 2013 May 12.

PMID:
23670170
8.

Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis.

Kristensen DM, Lesné L, Le Fol V, Desdoits-Lethimonier C, Dejucq-Rainsford N, Leffers H, Jégou B.

Int J Androl. 2012 Jun;35(3):377-84. doi: 10.1111/j.1365-2605.2012.01282.x.

PMID:
22612476
9.

Human testis steroidogenesis is inhibited by phthalates.

Desdoits-Lethimonier C, Albert O, Le Bizec B, Perdu E, Zalko D, Courant F, Lesné L, Guillé F, Dejucq-Rainsford N, Jégou B.

Hum Reprod. 2012 May;27(5):1451-9. doi: 10.1093/humrep/des069. Epub 2012 Mar 8.

PMID:
22402212
10.

Many putative endocrine disruptors inhibit prostaglandin synthesis.

Kristensen DM, Skalkam ML, Audouze K, Lesné L, Desdoits-Lethimonier C, Frederiksen H, Brunak S, Skakkebæk NE, Jégou B, Hansen JB, Junker S, Leffers H.

Environ Health Perspect. 2011 Apr;119(4):534-41. doi: 10.1289/ehp.1002635. Epub 2010 Nov 16.

11.

Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat.

Kristensen DM, Hass U, Lesné L, Lottrup G, Jacobsen PR, Desdoits-Lethimonier C, Boberg J, Petersen JH, Toppari J, Jensen TK, Brunak S, Skakkebaek NE, Nellemann C, Main KM, Jégou B, Leffers H.

Hum Reprod. 2011 Jan;26(1):235-44. doi: 10.1093/humrep/deq323. Epub 2010 Nov 8.

PMID:
21059752

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