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Items: 17


Single-cell Wnt signaling niches maintain stemness of alveolar type 2 cells.

Nabhan A, Brownfield DG, Harbury PB, Krasnow MA, Desai TJ.

Science. 2018 Feb 1. pii: eaam6603. doi: 10.1126/science.aam6603. [Epub ahead of print]


Automated cell-type classification in intact tissues by single-cell molecular profiling.

Nagendran M, Riordan DP, Harbury PB, Desai TJ.

Elife. 2018 Jan 10;7. pii: e30510. doi: 10.7554/eLife.30510.


Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease.

Oak P, Pritzke T, Thiel I, Koschlig M, Mous DS, Windhorst A, Jain N, Eickelberg O, Foerster K, Schulze A, Goepel W, Reicherzer T, Ehrhardt H, Rottier RJ, Ahnert P, Gortner L, Desai TJ, Hilgendorff A.

EMBO Mol Med. 2017 Nov;9(11):1504-1520. doi: 10.15252/emmm.201607308.


Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung.

Guo H, Kazadaeva Y, Ortega FE, Manjunath N, Desai TJ.

Dev Biol. 2017 Oct 1;430(1):214-223. doi: 10.1016/j.ydbio.2017.07.018. Epub 2017 Aug 12.


A comprehensive lipid binding and activity validation of a cancer-specific peptide-peptoid hybrid PPS1.

Desai TJ, Udugamasooriya DG.

Biochem Biophys Res Commun. 2017 Apr 29;486(2):545-550. doi: 10.1016/j.bbrc.2017.03.083. Epub 2017 Mar 18.


Identification of the minimum pharmacophore of lipid-phosphatidylserine (PS) binding peptide-peptoid hybrid PPS1D1.

Singh J, Shukla SP, Desai TJ, Udugamasooriya DG.

Bioorg Med Chem. 2016 Sep 15;24(18):4470-4477. doi: 10.1016/j.bmc.2016.07.045. Epub 2016 Jul 21.


Identification of lipid-phosphatidylserine (PS) as the target of unbiasedly selected cancer specific peptide-peptoid hybrid PPS1.

Desai TJ, Toombs JE, Minna JD, Brekken RA, Udugamasooriya DG.

Oncotarget. 2016 May 24;7(21):30678-90. doi: 10.18632/oncotarget.8929.


Keeping it together: Pulmonary alveoli are maintained by a hierarchy of cellular programs.

Logan CY, Desai TJ.

Bioessays. 2015 Sep;37(9):1028-37. doi: 10.1002/bies.201500031. Epub 2015 Jul 22. Review.


Cellular mechanisms of alveolar pathology in childhood interstitial lung diseases: current insights from mouse genetics.

Kuo CS, Desai TJ.

Curr Opin Pediatr. 2015 Jun;27(3):341-7. doi: 10.1097/MOP.0000000000000227. Review.


Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq.

Treutlein B, Brownfield DG, Wu AR, Neff NF, Mantalas GL, Espinoza FH, Desai TJ, Krasnow MA, Quake SR.

Nature. 2014 May 15;509(7500):371-5. doi: 10.1038/nature13173. Epub 2014 Apr 13.


Alveolar progenitor and stem cells in lung development, renewal and cancer.

Desai TJ, Brownfield DG, Krasnow MA.

Nature. 2014 Mar 13;507(7491):190-4. doi: 10.1038/nature12930. Epub 2014 Feb 5.


Stem cells: Differentiated cells in a back-up role.

Desai TJ, Krasnow MA.

Nature. 2013 Nov 14;503(7475):204-5. doi: 10.1038/nature12706. Epub 2013 Nov 6. No abstract available.


Inhibition of Tgf beta signaling by endogenous retinoic acid is essential for primary lung bud induction.

Chen F, Desai TJ, Qian J, Niederreither K, Lü J, Cardoso WV.

Development. 2007 Aug;134(16):2969-79. Epub 2007 Jul 18.


Distinct roles for retinoic acid receptors alpha and beta in early lung morphogenesis.

Desai TJ, Chen F, Lü J, Qian J, Niederreither K, Dollé P, Chambon P, Cardoso WV.

Dev Biol. 2006 Mar 1;291(1):12-24. Epub 2006 Jan 19.


Retinoic acid selectively regulates Fgf10 expression and maintains cell identity in the prospective lung field of the developing foregut.

Desai TJ, Malpel S, Flentke GR, Smith SM, Cardoso WV.

Dev Biol. 2004 Sep 15;273(2):402-15.


Growth factors in lung development and disease: friends or foe?

Desai TJ, Cardoso WV.

Respir Res. 2002;3:2. Epub 2001 Oct 9. Review.


Participation of urokinase-type plasminogen activator receptor in the clearance of fibrin from the lung.

Hattori N, Sisson TH, Xu Y, Desai TJ, Simon RH.

Am J Physiol. 1999 Sep;277(3 Pt 1):L573-9.


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