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Items: 17

1.

Identification, isolation and characterization of human LGR5-positive colon adenoma cells.

Dame MK, Attili D, McClintock SD, Dedhia PH, Ouillette P, Hardt O, Chin AM, Xue X, Laliberte J, Katz EL, Newsome GM, Hill DR, Miller AJ, Tsai YH, Agorku D, Altheim CH, Bosio A, Simon B, Samuelson LC, Stoerker JA, Appelman HD, Varani J, Wicha MS, Brenner DE, Shah YM, Spence JR, Colacino JA.

Development. 2018 Mar 14;145(6). pii: dev153049. doi: 10.1242/dev.153049.

PMID:
29467240
2.

Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium.

Hill DR, Huang S, Nagy MS, Yadagiri VK, Fields C, Mukherjee D, Bons B, Dedhia PH, Chin AM, Tsai YH, Thodla S, Schmidt TM, Walk S, Young VB, Spence JR.

Elife. 2017 Nov 7;6. pii: e29132. doi: 10.7554/eLife.29132.

3.

Reduced paraspinous muscle area is associated with post-colectomy complications in children with ulcerative colitis.

Dedhia PH, White Y, Dillman JR, Adler J, Jarboe MD, Teitelbaum DH, Hirschl RB, Gadepalli SK.

J Pediatr Surg. 2018 Mar;53(3):477-482. doi: 10.1016/j.jpedsurg.2017.09.006. Epub 2017 Sep 14.

PMID:
29103786
4.

Synthetic hydrogels for human intestinal organoid generation and colonic wound repair.

Cruz-Acuña R, Quirós M, Farkas AE, Dedhia PH, Huang S, Siuda D, García-Hernández V, Miller AJ, Spence JR, Nusrat A, García AJ.

Nat Cell Biol. 2017 Nov;19(11):1326-1335. doi: 10.1038/ncb3632. Epub 2017 Oct 23.

PMID:
29058719
5.

Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling.

Quiros M, Nishio H, Neumann PA, Siuda D, Brazil JC, Azcutia V, Hilgarth R, O'Leary MN, Garcia-Hernandez V, Leoni G, Feng M, Bernal G, Williams H, Dedhia PH, Gerner-Smidt C, Spence J, Parkos CA, Denning TL, Nusrat A.

J Clin Invest. 2017 Sep 1;127(9):3510-3520. doi: 10.1172/JCI90229. Epub 2017 Aug 7.

6.

Chronic stress and intestinal barrier dysfunction: Glucocorticoid receptor and transcription repressor HES1 regulate tight junction protein Claudin-1 promoter.

Zheng G, Victor Fon G, Meixner W, Creekmore A, Zong Y, K Dame M, Colacino J, Dedhia PH, Hong S, Wiley JW.

Sci Rep. 2017 Jul 3;7(1):4502. doi: 10.1038/s41598-017-04755-w.

7.

It's worth the wait: optimizing questioning methods for effective intraoperative teaching.

Barrett M, Magas CP, Gruppen LD, Dedhia PH, Sandhu G.

ANZ J Surg. 2017 Jul;87(7-8):541-546. doi: 10.1111/ans.14046. Epub 2017 Jun 7.

PMID:
28593692
8.

Regeneration of fat cells from myofibroblasts during wound healing.

Plikus MV, Guerrero-Juarez CF, Ito M, Li YR, Dedhia PH, Zheng Y, Shao M, Gay DL, Ramos R, Hsi TC, Oh JW, Wang X, Ramirez A, Konopelski SE, Elzein A, Wang A, Supapannachart RJ, Lee HL, Lim CH, Nace A, Guo A, Treffeisen E, Andl T, Ramirez RN, Murad R, Offermanns S, Metzger D, Chambon P, Widgerow AD, Tuan TL, Mortazavi A, Gupta RK, Hamilton BA, Millar SE, Seale P, Pear WS, Lazar MA, Cotsarelis G.

Science. 2017 Feb 17;355(6326):748-752. doi: 10.1126/science.aai8792. Epub 2017 Jan 5.

9.

In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development.

Tsai YH, Nattiv R, Dedhia PH, Nagy MS, Chin AM, Thomson M, Klein OD, Spence JR.

Development. 2017 Mar 15;144(6):1045-1055. doi: 10.1242/dev.138453. Epub 2016 Dec 7.

10.

A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids.

Dye BR, Dedhia PH, Miller AJ, Nagy MS, White ES, Shea LD, Spence JR.

Elife. 2016 Sep 28;5. pii: e19732. doi: 10.7554/eLife.19732.

11.

Intraoperative questioning to advance higher-order thinking.

Magas CP, Gruppen LD, Barrett M, Dedhia PH, Sandhu G.

Am J Surg. 2017 Feb;213(2):222-226. doi: 10.1016/j.amjsurg.2016.08.027. Epub 2016 Oct 8.

PMID:
27765181
12.

Notch1 and Notch2 receptors regulate mouse and human gastric antral epithelial cell homoeostasis.

Gifford GB, Demitrack ES, Keeley TM, Tam A, La Cunza N, Dedhia PH, Spence JR, Simeone DM, Saotome I, Louvi A, Siebel CW, Samuelson LC.

Gut. 2017 Jun;66(6):1001-1011. doi: 10.1136/gutjnl-2015-310811. Epub 2016 Mar 1.

13.

Organoid Models of Human Gastrointestinal Development and Disease.

Dedhia PH, Bertaux-Skeirik N, Zavros Y, Spence JR.

Gastroenterology. 2016 May;150(5):1098-1112. doi: 10.1053/j.gastro.2015.12.042. Epub 2016 Jan 14. Review.

14.

Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo.

Finkbeiner SR, Hill DR, Altheim CH, Dedhia PH, Taylor MJ, Tsai YH, Chin AM, Mahe MM, Watson CL, Freeman JJ, Nattiv R, Thomson M, Klein OD, Shroyer NF, Helmrath MA, Teitelbaum DH, Dempsey PJ, Spence JR.

Stem Cell Reports. 2015 Jun 3. pii: S2213-6711(15)00122-8. doi: 10.1016/j.stemcr.2015.04.010. [Epub ahead of print]

15.

Potential effects of molecular testing of indeterminate thyroid nodule fine needle aspiration biopsy on thyroidectomy volume.

Dedhia PH, Rubio GA, Cohen MS, Miller BS, Gauger PG, Hughes DT.

World J Surg. 2014 Mar;38(3):634-8. doi: 10.1007/s00268-013-2430-x.

PMID:
24435929
16.

Transformation by Tribbles homolog 2 (Trib2) requires both the Trib2 kinase domain and COP1 binding.

Keeshan K, Bailis W, Dedhia PH, Vega ME, Shestova O, Xu L, Toscano K, Uljon SN, Blacklow SC, Pear WS.

Blood. 2010 Dec 2;116(23):4948-57. doi: 10.1182/blood-2009-10-247361. Epub 2010 Aug 30.

17.

Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia.

Dedhia PH, Keeshan K, Uljon S, Xu L, Vega ME, Shestova O, Zaks-Zilberman M, Romany C, Blacklow SC, Pear WS.

Blood. 2010 Aug 26;116(8):1321-8. doi: 10.1182/blood-2009-07-229450. Epub 2010 Apr 21.

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