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Items: 1 to 50 of 358

1.

Light-activated protein interaction with high spatial subcellular confinement.

Benedetti L, Barentine AES, Messa M, Wheeler H, Bewersdorf J, De Camilli P.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2238-E2245. doi: 10.1073/pnas.1713845115. Epub 2018 Feb 20.

PMID:
29463750
2.

A lentiviral system for efficient knockdown of proteins in neuronal cultures [version 1; referees: 2 approved].

Ritter B, Ferguson SM, De Camilli P, McPherson PS.

MNI Open Res. 2017;1(2). doi: 10.12688/mniopenres.12766.1. Epub 2017 Dec 5.

3.

Architecture of the human PI4KIIIα lipid kinase complex.

Lees JA, Zhang Y, Oh MS, Schauder CM, Yu X, Baskin JM, Dobbs K, Notarangelo LD, De Camilli P, Walz T, Reinisch KM.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13720-13725. doi: 10.1073/pnas.1718471115. Epub 2017 Dec 11.

PMID:
29229838
4.

Ca2+ releases E-Syt1 autoinhibition to couple ER-plasma membrane tethering with lipid transport.

Bian X, Saheki Y, De Camilli P.

EMBO J. 2018 Jan 17;37(2):219-234. doi: 10.15252/embj.201797359. Epub 2017 Dec 8.

PMID:
29222176
5.

Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers.

Stefan CJ, Trimble WS, Grinstein S, Drin G, Reinisch K, De Camilli P, Cohen S, Valm AM, Lippincott-Schwartz J, Levine TP, Iaea DB, Maxfield FR, Futter CE, Eden ER, Judith D, van Vliet AR, Agostinis P, Tooze SA, Sugiura A, McBride HM.

BMC Biol. 2017 Oct 31;15(1):102. doi: 10.1186/s12915-017-0432-0.

6.

Single-molecule force spectroscopy of protein-membrane interactions.

Ma L, Cai Y, Li Y, Jiao J, Wu Z, O'Shaughnessy B, De Camilli P, Karatekin E, Zhang Y.

Elife. 2017 Oct 30;6. pii: e30493. doi: 10.7554/eLife.30493.

7.

Structural inhibition of dynamin-mediated membrane fission by endophilin.

Hohendahl A, Talledge N, Galli V, Shen PS, Humbert F, De Camilli P, Frost A, Roux A.

Elife. 2017 Sep 21;6. pii: e26856. doi: 10.7554/eLife.26856.

8.

Contacts between the endoplasmic reticulum and other membranes in neurons.

Wu Y, Whiteus C, Xu CS, Hayworth KJ, Weinberg RJ, Hess HF, De Camilli P.

Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4859-E4867. doi: 10.1073/pnas.1701078114. Epub 2017 May 30.

9.

Loss of Dynamin 2 GTPase function results in microcytic anaemia.

Brown FC, Collett M, Tremblay CS, Rank G, De Camilli P, Booth CJ, Bitoun M, Robinson PJ, Kile BT, Jane SM, Curtis DJ.

Br J Haematol. 2017 Aug;178(4):616-628. doi: 10.1111/bjh.14709. Epub 2017 May 3.

PMID:
28466468
10.

The Extended-Synaptotagmins.

Saheki Y, De Camilli P.

Biochim Biophys Acta. 2017 Sep;1864(9):1490-1493. doi: 10.1016/j.bbamcr.2017.03.013. Epub 2017 Mar 28. Review.

PMID:
28363589
11.

Endoplasmic Reticulum-Plasma Membrane Contact Sites.

Saheki Y, De Camilli P.

Annu Rev Biochem. 2017 Jun 20;86:659-684. doi: 10.1146/annurev-biochem-061516-044932. Epub 2017 Feb 23. Review.

PMID:
28301744
12.

Synaptic Vesicle Clusters at Synapses: A Distinct Liquid Phase?

Milovanovic D, De Camilli P.

Neuron. 2017 Mar 8;93(5):995-1002. doi: 10.1016/j.neuron.2017.02.013. Review.

13.

Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons.

Cao M, Wu Y, Ashrafi G, McCartney AJ, Wheeler H, Bushong EA, Boassa D, Ellisman MH, Ryan TA, De Camilli P.

Neuron. 2017 Feb 22;93(4):882-896.e5. doi: 10.1016/j.neuron.2017.01.019.

14.

Lipid transport by TMEM24 at ER-plasma membrane contacts regulates pulsatile insulin secretion.

Lees JA, Messa M, Sun EW, Wheeler H, Torta F, Wenk MR, De Camilli P, Reinisch KM.

Science. 2017 Feb 17;355(6326). pii: eaah6171. doi: 10.1126/science.aah6171.

15.

Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis.

Levin R, Hammond GR, Balla T, De Camilli P, Fairn GD, Grinstein S.

Mol Biol Cell. 2017 Jan 1;28(1):128-140. doi: 10.1091/mbc.E16-06-0451. Epub 2016 Nov 9.

16.

Kidney Tubular Ablation of Ocrl/Inpp5b Phenocopies Lowe Syndrome Tubulopathy.

Inoue K, Balkin DM, Liu L, Nandez R, Wu Y, Tian X, Wang T, Nussbaum R, De Camilli P, Ishibe S.

J Am Soc Nephrol. 2017 May;28(5):1399-1407. doi: 10.1681/ASN.2016080913. Epub 2016 Nov 28.

17.

Membrane fission by dynamin: what we know and what we need to know.

Antonny B, Burd C, De Camilli P, Chen E, Daumke O, Faelber K, Ford M, Frolov VA, Frost A, Hinshaw JE, Kirchhausen T, Kozlov MM, Lenz M, Low HH, McMahon H, Merrifield C, Pollard TD, Robinson PJ, Roux A, Schmid S.

EMBO J. 2016 Nov 2;35(21):2270-2284. Epub 2016 Sep 26. Review.

18.

Loss of SYNJ1 dual phosphatase activity leads to early onset refractory seizures and progressive neurological decline.

Hardies K, Cai Y, Jardel C, Jansen AC, Cao M, May P, Djémié T, Hachon Le Camus C, Keymolen K, Deconinck T, Bhambhani V, Long C, Sajan SA, Helbig KL; AR working group of the EuroEPINOMICS RES Consortium, Suls A, Balling R, Helbig I, De Jonghe P, Depienne C, De Camilli P, Weckhuysen S.

Brain. 2016 Sep;139(Pt 9):2420-30. doi: 10.1093/brain/aww180. Epub 2016 Jul 19.

19.

Endosome-ER Contacts Control Actin Nucleation and Retromer Function through VAP-Dependent Regulation of PI4P.

Dong R, Saheki Y, Swarup S, Lucast L, Harper JW, De Camilli P.

Cell. 2016 Jul 14;166(2):408-423. doi: 10.1016/j.cell.2016.06.037.

20.

The endocytic activity of the flagellar pocket in Trypanosoma brucei is regulated by an adjacent phosphatidylinositol phosphate kinase.

Demmel L, Schmidt K, Lucast L, Havlicek K, Zankel A, Koestler T, Reithofer V, de Camilli P, Warren G.

J Cell Sci. 2016 Jun 1;129(11):2285. doi: 10.1242/jcs.191569. No abstract available.

21.

Control of plasma membrane lipid homeostasis by the extended synaptotagmins.

Saheki Y, Bian X, Schauder CM, Sawaki Y, Surma MA, Klose C, Pincet F, Reinisch KM, De Camilli P.

Nat Cell Biol. 2016 May;18(5):504-15. doi: 10.1038/ncb3339. Epub 2016 Apr 11.

22.

SMP-domain proteins at membrane contact sites: Structure and function.

Reinisch KM, De Camilli P.

Biochim Biophys Acta. 2016 Aug;1861(8 Pt B):924-927. doi: 10.1016/j.bbalip.2015.12.003. Epub 2015 Dec 10. Review.

23.

The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane.

Baskin JM, Wu X, Christiano R, Oh MS, Schauder CM, Gazzerro E, Messa M, Baldassari S, Assereto S, Biancheri R, Zara F, Minetti C, Raimondi A, Simons M, Walther TC, Reinisch KM, De Camilli P.

Nat Cell Biol. 2016 Jan;18(1):132-8. doi: 10.1038/ncb3271. Epub 2015 Nov 16.

24.

INTRACELLULAR TRANSPORT. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts.

Chung J, Torta F, Masai K, Lucast L, Czapla H, Tanner LB, Narayanaswamy P, Wenk MR, Nakatsu F, De Camilli P.

Science. 2015 Jul 24;349(6246):428-32. doi: 10.1126/science.aab1370.

25.

Triggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering.

Idevall-Hagren O, Lü A, Xie B, De Camilli P.

EMBO J. 2015 Sep 2;34(17):2291-305. doi: 10.15252/embj.201591565. Epub 2015 Jul 22.

26.

The BioPlex Network: A Systematic Exploration of the Human Interactome.

Huttlin EL, Ting L, Bruckner RJ, Gebreab F, Gygi MP, Szpyt J, Tam S, Zarraga G, Colby G, Baltier K, Dong R, Guarani V, Vaites LP, Ordureau A, Rad R, Erickson BK, Wühr M, Chick J, Zhai B, Kolippakkam D, Mintseris J, Obar RA, Harris T, Artavanis-Tsakonas S, Sowa ME, De Camilli P, Paulo JA, Harper JW, Gygi SP.

Cell. 2015 Jul 16;162(2):425-440. doi: 10.1016/j.cell.2015.06.043.

27.

Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer's disease amyloid plaques.

Gowrishankar S, Yuan P, Wu Y, Schrag M, Paradise S, Grutzendler J, De Camilli P, Ferguson SM.

Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):E3699-708. doi: 10.1073/pnas.1510329112. Epub 2015 Jun 29.

28.

Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway.

Nakatsu F, Messa M, Nández R, Czapla H, Zou Y, Strittmatter SM, De Camilli P.

J Cell Biol. 2015 Apr 13;209(1):85-95. doi: 10.1083/jcb.201409064.

29.

Dynamin 2-dependent endocytosis sustains T-cell receptor signaling and drives metabolic reprogramming in T lymphocytes.

Willinger T, Staron M, Ferguson SM, De Camilli P, Flavell RA.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4423-8. doi: 10.1073/pnas.1504279112. Epub 2015 Mar 23.

30.

Three-dimensional architecture of extended synaptotagmin-mediated endoplasmic reticulum-plasma membrane contact sites.

Fernández-Busnadiego R, Saheki Y, De Camilli P.

Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):E2004-13. doi: 10.1073/pnas.1503191112. Epub 2015 Mar 18.

31.

Preface.

De Matteis A, De Camilli P.

Biochim Biophys Acta. 2015 Jun;1851(6):697. doi: 10.1016/j.bbalip.2015.02.009. Epub 2015 Feb 18. No abstract available.

PMID:
25701448
32.

Plasticity of PI4KIIIα interactions at the plasma membrane.

Chung J, Nakatsu F, Baskin JM, De Camilli P.

EMBO Rep. 2015 Mar;16(3):312-20. doi: 10.15252/embr.201439151. Epub 2015 Jan 21.

33.

Detection and manipulation of phosphoinositides.

Idevall-Hagren O, De Camilli P.

Biochim Biophys Acta. 2015 Jun;1851(6):736-45. doi: 10.1016/j.bbalip.2014.12.008. Epub 2014 Dec 13. Review.

34.

Upregulation of Parkin in endophilin mutant mice.

Cao M, Milosevic I, Giovedi S, De Camilli P.

J Neurosci. 2014 Dec 3;34(49):16544-9. doi: 10.1523/JNEUROSCI.1710-14.2014.

35.

Dynamin and endocytosis are required for the fusion of osteoclasts and myoblasts.

Shin NY, Choi H, Neff L, Wu Y, Saito H, Ferguson SM, De Camilli P, Baron R.

J Cell Biol. 2014 Oct 13;207(1):73-89. doi: 10.1083/jcb.201401137. Epub 2014 Oct 6.

36.

Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits.

Messa M, Fernández-Busnadiego R, Sun EW, Chen H, Czapla H, Wrasman K, Wu Y, Ko G, Ross T, Wendland B, De Camilli P.

Elife. 2014 Aug 13;3:e03311. doi: 10.7554/eLife.03311.

37.

A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells.

Nández R, Balkin DM, Messa M, Liang L, Paradise S, Czapla H, Hein MY, Duncan JS, Mann M, De Camilli P.

Elife. 2014 Aug 8;3:e02975. doi: 10.7554/eLife.02975.

38.

The machinery at endoplasmic reticulum-plasma membrane contact sites contributes to spatial regulation of multiple Legionella effector proteins.

Hubber A, Arasaki K, Nakatsu F, Hardiman C, Lambright D, De Camilli P, Nagai H, Roy CR.

PLoS Pathog. 2014 Jul 3;10(7):e1004222. doi: 10.1371/journal.ppat.1004222. eCollection 2014 Jul.

39.

A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis.

Wu Y, O'Toole ET, Girard M, Ritter B, Messa M, Liu X, McPherson PS, Ferguson SM, De Camilli P.

Elife. 2014 Jun 24;3:e01621. doi: 10.7554/eLife.01621.

40.

Coupling between endocytosis and sphingosine kinase 1 recruitment.

Shen H, Giordano F, Wu Y, Chan J, Zhu C, Milosevic I, Wu X, Yao K, Chen B, Baumgart T, Sieburth D, De Camilli P.

Nat Cell Biol. 2014 Jul;16(7):652-62. doi: 10.1038/ncb2987. Epub 2014 Jun 15.

41.

Rare deleterious mutations of the gene EFR3A in autism spectrum disorders.

Gupta AR, Pirruccello M, Cheng F, Kang HJ, Fernandez TV, Baskin JM, Choi M, Liu L, Ercan-Sencicek AG, Murdoch JD, Klei L, Neale BM, Franjic D, Daly MJ, Lifton RP, De Camilli P, Zhao H, Sestan N, State MW.

Mol Autism. 2014 Apr 29;5:31. doi: 10.1186/2040-2392-5-31. eCollection 2014.

42.

Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer.

Schauder CM, Wu X, Saheki Y, Narayanaswamy P, Torta F, Wenk MR, De Camilli P, Reinisch KM.

Nature. 2014 Jun 26;510(7506):552-5.

43.

A novel multiple hypothesis based particle tracking method for clathrin mediated endocytosis analysis using fluorescence microscopy.

Liang Liang, Hongying Shen, De Camilli P, Duncan JS.

IEEE Trans Image Process. 2014 Apr;23(4):1844-57. doi: 10.1109/TIP.2014.2303633.

44.

Identification of inhibitors of inositol 5-phosphatases through multiple screening strategies.

Pirruccello M, Nandez R, Idevall-Hagren O, Alcazar-Roman A, Abriola L, Berwick SA, Lucast L, Morel D, De Camilli P.

ACS Chem Biol. 2014 Jun 20;9(6):1359-68. doi: 10.1021/cb500161z. Epub 2014 May 1.

45.

The endocytic activity of the flagellar pocket in Trypanosoma brucei is regulated by an adjacent phosphatidylinositol phosphate kinase.

Demmel L, Schmidt K, Lucast L, Havlicek K, Zankel A, Koestler T, Reithofer V, de Camilli P, Warren G.

J Cell Sci. 2014 May 15;127(Pt 10):2351-64. doi: 10.1242/jcs.146894. Epub 2014 Mar 17. Erratum in: J Cell Sci. 2016 Jun 1;129(11):2285.

46.

Dynamin 2-dependent endocytosis is required for sustained S1PR1 signaling.

Willinger T, Ferguson SM, Pereira JP, De Camilli P, Flavell RA.

J Exp Med. 2014 Apr 7;211(4):685-700. doi: 10.1084/jem.20131343. Epub 2014 Mar 17.

47.

Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis.

Lee MY, Skoura A, Park EJ, Landskroner-Eiger S, Jozsef L, Luciano AK, Murata T, Pasula S, Dong Y, Bouaouina M, Calderwood DA, Ferguson SM, De Camilli P, Sessa WC.

Development. 2014 Apr;141(7):1465-72. doi: 10.1242/dev.104539. Epub 2014 Mar 5.

48.

Structural insights into assembly and regulation of the plasma membrane phosphatidylinositol 4-kinase complex.

Wu X, Chi RJ, Baskin JM, Lucast L, Burd CG, De Camilli P, Reinisch KM.

Dev Cell. 2014 Jan 13;28(1):19-29. doi: 10.1016/j.devcel.2013.11.012. Epub 2013 Dec 19.

49.

Essential function of dynamin in the invasive properties and actin architecture of v-Src induced podosomes/invadosomes.

Destaing O, Ferguson SM, Grichine A, Oddou C, De Camilli P, Albiges-Rizo C, Baron R.

PLoS One. 2013 Dec 9;8(12):e77956. doi: 10.1371/journal.pone.0077956. eCollection 2013.

50.

Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis.

Devereaux K, Dall'Armi C, Alcazar-Roman A, Ogasawara Y, Zhou X, Wang F, Yamamoto A, De Camilli P, Di Paolo G.

PLoS One. 2013 Oct 3;8(10):e76405. doi: 10.1371/journal.pone.0076405. eCollection 2013.

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