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Items: 19

1.

Effect of Cryopreservation on Enzyme and Transporter Activities in Suspended and Sandwich Cultured Rat Hepatocytes.

Keemink J, Deferm N, De Bruyn T, Augustijns P, Bouillon T, Annaert P.

AAPS J. 2018 Feb 21;20(2):33. doi: 10.1208/s12248-018-0188-7.

PMID:
29468289
2.

Simultaneous Assessment in vitro of Transporter and Metabolic Processes in Hepatic Drug Clearance: Use of a media loss approach.

Harrison J, De Bruyn T, Darwich AS, Houston JB.

Drug Metab Dispos. 2018 Feb 8. pii: dmd.117.079590. doi: 10.1124/dmd.117.079590. [Epub ahead of print]

PMID:
29439129
3.

Transport-Metabolism Interplay of Atazanavir in Rat Hepatocytes.

Nicolaï J, De Bruyn T, Thevelin L, Augustijns P, Annaert P.

Drug Metab Dispos. 2016 Mar;44(3):389-97. doi: 10.1124/dmd.115.068114. Epub 2015 Dec 28.

4.

Clearance Prediction of HIV Protease Inhibitors in Man: Role of Hepatic Uptake.

De Bruyn T, Stieger B, Augustijns PF, Annaert PP.

J Pharm Sci. 2016 Feb;105(2):854-863. doi: 10.1002/jps.24564. Epub 2016 Jan 11.

5.

Hepatic Clearance Prediction of Nine Human Immunodeficiency Virus Protease Inhibitors in Rat.

De Bruyn T, Augustijns PF, Annaert PP.

J Pharm Sci. 2016 Feb;105(2):846-853. doi: 10.1002/jps.24559. Epub 2016 Jan 12.

PMID:
26202434
6.

Verapamil hepatic clearance in four preclinical rat models: towards activity-based scaling.

Nicolaï J, De Bruyn T, Van Veldhoven PP, Keemink J, Augustijns P, Annaert P.

Biopharm Drug Dispos. 2015 Oct;36(7):462-80. doi: 10.1002/bdd.1959. Epub 2015 Jun 11.

PMID:
25963583
7.

Confocal imaging with a fluorescent bile acid analogue closely mimicking hepatic taurocholate disposition.

De Bruyn T, Sempels W, Snoeys J, Holmstock N, Chatterjee S, Stieger B, Augustijns P, Hofkens J, Mizuno H, Annaert P.

J Pharm Sci. 2014 Jun;103(6):1872-81. doi: 10.1002/jps.23933. Epub 2014 Mar 20.

PMID:
24652646
8.

Structure-based identification of OATP1B1/3 inhibitors.

De Bruyn T, van Westen GJ, Ijzerman AP, Stieger B, de Witte P, Augustijns PF, Annaert PP.

Mol Pharmacol. 2013 Jun;83(6):1257-67. doi: 10.1124/mol.112.084152. Epub 2013 Apr 9.

9.

Sandwich-cultured hepatocytes: utility for in vitro exploration of hepatobiliary drug disposition and drug-induced hepatotoxicity.

De Bruyn T, Chatterjee S, Fattah S, Keemink J, Nicolaï J, Augustijns P, Annaert P.

Expert Opin Drug Metab Toxicol. 2013 May;9(5):589-616. doi: 10.1517/17425255.2013.773973. Epub 2013 Mar 2. Review.

PMID:
23452081
10.

Exploring food effects on indinavir absorption with human intestinal fluids in the mouse intestine.

Holmstock N, De Bruyn T, Bevernage J, Annaert P, Mols R, Tack J, Augustijns P.

Eur J Pharm Sci. 2013 Apr 11;49(1):27-32. doi: 10.1016/j.ejps.2013.01.012. Epub 2013 Feb 9.

PMID:
23402972
11.

Stability of therapeutic albumin solutions used for molecular adsorbent recirculating system-based liver dialysis.

De Bruyn T, Meijers B, Evenepoel P, Laub R, Willems L, Augustijns P, Annaert P.

Artif Organs. 2012 Jan;36(1):29-41. doi: 10.1111/j.1525-1594.2011.01310.x. Epub 2011 Sep 28.

PMID:
21955219
12.

Sodium fluorescein is a probe substrate for hepatic drug transport mediated by OATP1B1 and OATP1B3.

De Bruyn T, Fattah S, Stieger B, Augustijns P, Annaert P.

J Pharm Sci. 2011 Nov;100(11):5018-30. doi: 10.1002/jps.22694. Epub 2011 Aug 11.

PMID:
21837650
13.

Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes.

De Bruyn T, Ye ZW, Peeters A, Sahi J, Baes M, Augustijns PF, Annaert PP.

Eur J Pharm Sci. 2011 Jul 17;43(4):297-307. doi: 10.1016/j.ejps.2011.05.002. Epub 2011 May 14.

PMID:
21605667
14.

Nova Scotia renews its HIV/AIDS strategy.

de Bruyn T.

Can HIV AIDS Policy Law Rev. 2004 Aug;9(2):24.

PMID:
15540327
15.

Survey reveals knowledge and attitudes of Canadians regarding HIV/AIDS.

de Bruyn T, Garmaise D.

Can HIV AIDS Policy Law Rev. 2003 Dec;8(3):31-2.

PMID:
15108647
16.

Compulsory HIV testing after an occupational exposure.

de Bruyn T, Elliott R.

Can HIV AIDS Policy Law Rev. 2002 Mar;6(3):1, 24-31.

PMID:
14979225
17.

HIV-related stigma and discrimination--the epidemic continues.

de Bruyn T.

Can HIV AIDS Policy Law Rev. 2002 Jul;7(1):8-14.

PMID:
14765477
18.

RCMP lay charges in tainted-blood scandal.

de Bruyn T.

Can HIV AIDS Policy Law Rev. 2002 Dec;7(2-3):36. English, French. No abstract available.

PMID:
14719499
19.

[Pancuronium bromide--a new non-depolarizing muscle relaxant].

Kok OV, de Bruyn TB, Sevenster Gv, de Kock MJ, Lawrance WH, Badenhorst SJ.

S Afr Med J. 1969 Dec 6;43(48):1459-61. Afrikaans. No abstract available.

PMID:
4190216

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