Sort by

Send to

Choose Destination

Search results

Items: 3


Mapping the allosteric action of antagonists A740003 and A438079 reveals a role of the left flipper in ligand sensitivity at P2X7 receptors.

Allsopp RC, Dayl S, Bin Dayel A, Schmid R, Evans RJ.

Mol Pharmacol. 2018 Mar 13. pii: mol.117.111021. doi: 10.1124/mol.117.111021. [Epub ahead of print]


Unique residues in the ATP gated human P2X7 receptor define a novel allosteric binding pocket for the selective antagonist AZ10606120.

Allsopp RC, Dayl S, Schmid R, Evans RJ.

Sci Rep. 2017 Apr 7;7(1):725. doi: 10.1038/s41598-017-00732-5.


Mechanistic insights from resolving ligand-dependent kinetics of conformational changes at ATP-gated P2X1R ion channels.

Fryatt AG, Dayl S, Cullis PM, Schmid R, Evans RJ.

Sci Rep. 2016 Sep 12;6:32918. doi: 10.1038/srep32918.

Supplemental Content

Support Center