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Items: 1 to 50 of 120

1.

Attitudes and perceptions of health professionals towards management of hypothyroidism in general practice: a qualitative interview study.

Dew R, King K, Okosieme OE, Pearce SH, Donovan G, Taylor PN, Hickey J, Dayan CM, Leese G, Razvi S, Wilkes S.

BMJ Open. 2018 Feb 21;8(2):e019970. doi: 10.1136/bmjopen-2017-019970.

PMID:
29467136
2.

Combined immunosuppression and radiotherapy in thyroid eye disease (CIRTED): a multicentre, 2 × 2 factorial, double-blind, randomised controlled trial.

Rajendram R, Taylor PN, Wilson VJ, Harris N, Morris OC, Tomlinson M, Yarrow S, Garrott H, Herbert HM, Dick AD, Cook A, Gattamaneni R, Jain R, Olver J, Hurel SJ, Bremner F, Drummond SR, Kemp E, Ritchie DM, Rumsey N, Morris D, Lane C, Palaniappan N, Li C, Pell J, Hills R, Ezra DG, Potts MJ, Jackson S, Rose GE, Plowman N, Bunce C, Uddin JM, Lee RWJ, Dayan CM.

Lancet Diabetes Endocrinol. 2018 Jan 30. pii: S2213-8587(18)30021-4. doi: 10.1016/S2213-8587(18)30021-4. [Epub ahead of print]

PMID:
29396245
3.

TPOAb and Thyroid Function Are Not Associated with Breast Cancer Outcome: Evidence from a Large-Scale Study Using Data from the Taxotere as Adjuvant Chemotherapy Trial (TACT, CRUK01/001).

Muller I, Kilburn LS, Taylor PN, Barrett-Lee PJ, Bliss JM, Ellis P, Ludgate ME, Dayan CM.

Eur Thyroid J. 2017 Jul;6(4):197-207. doi: 10.1159/000460246. Epub 2017 Apr 4.

4.

Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes.

Alhadj Ali M, Liu YF, Arif S, Tatovic D, Shariff H, Gibson VB, Yusuf N, Baptista R, Eichmann M, Petrov N, Heck S, Yang JHM, Tree TIM, Pujol-Autonell I, Yeo L, Baumard LR, Stenson R, Howell A, Clark A, Boult Z, Powrie J, Adams L, Wong FS, Luzio S, Dunseath G, Green K, O'Keefe A, Bayly G, Thorogood N, Andrews R, Leech N, Joseph F, Nair S, Seal S, Cheung H, Beam C, Hills R, Peakman M, Dayan CM.

Sci Transl Med. 2017 Aug 9;9(402). pii: eaaf7779. doi: 10.1126/scitranslmed.aaf7779.

PMID:
28794283
5.

Maturation in Serum Thyroid Function Parameters Over Childhood and Puberty: Results of a Longitudinal Study.

Taylor PN, Sayers A, Okosieme O, Das G, Draman MS, Tabasum A, Abusahmin H, Rahman M, Stevenson K, Groom A, Northstone K, Woltersdorf W, Taylor A, Ring S, Lazarus JH, Gregory JW, Rees A, Timpson N, Dayan CM.

J Clin Endocrinol Metab. 2017 Jul 1;102(7):2508-2515. doi: 10.1210/jc.2016-3605.

6.

The Role of Thyrotropin Receptor Activation in Adipogenesis and Modulation of Fat Phenotype.

Draman MS, Stechman M, Scott-Coombes D, Dayan CM, Rees DA, Ludgate M, Zhang L.

Front Endocrinol (Lausanne). 2017 Apr 19;8:83. doi: 10.3389/fendo.2017.00083. eCollection 2017.

7.

Management of thyroid eye disease in the United Kingdom: A multi-centre thyroid eye disease audit.

Mellington FE, Dayan CM, Dickinson AJ, Hickey JL, MacEwen CJ, McLaren J, Perros P, Rose GE, Uddin J, Vaidya B, Foley P, Lazarus JH, Mitchell A, Ezra DG; Thyroid Eye Disease Amsterdam Declaration Implementation Group (TEAMeD).

Orbit. 2017 Jun;36(3):159-169. doi: 10.1080/01676830.2017.1280057. Epub 2017 Mar 15.

PMID:
28296512
8.

Formulation of hydrophobic peptides for skin delivery via coated microneedles.

Zhao X, Coulman SA, Hanna SJ, Wong FS, Dayan CM, Birchall JC.

J Control Release. 2017 Nov 10;265:2-13. doi: 10.1016/j.jconrel.2017.03.015. Epub 2017 Mar 9.

PMID:
28286315
9.

An Invitation to Join the Consortium on Thyroid and Pregnancy.

Korevaar TI, Taylor PN, Dayan CM, Peeters RP.

Eur Thyroid J. 2016 Dec;5(4):277. doi: 10.1159/000452331. Epub 2016 Nov 17. No abstract available.

10.

Stimulated urine C-peptide creatinine ratio vs serum C-peptide level for monitoring of β-cell function in the first year after diagnosis of Type 1 diabetes.

Tatovic D, Luzio S, Dunseath G, Liu Y, Alhadj Ali M, Peakman M, Dayan CM; MonoPepT1De Study Group.

Diabet Med. 2016 Nov;33(11):1564-1568. doi: 10.1111/dme.13186. Epub 2016 Aug 8.

PMID:
27425010
11.

An Invitation to Join the Consortium on Thyroid and Pregnancy.

Korevaar TI, Taylor PN, Dayan CM, Peeters RP.

Obstet Gynecol. 2016 Oct;128(4):913. doi: 10.1097/AOG.0000000000001670. No abstract available.

PMID:
27661637
12.

β-cell specific T-lymphocyte response has a distinct inflammatory phenotype in children with Type 1 diabetes compared with adults.

Arif S, Gibson VB, Nguyen V, Bingley PJ, Todd JA, Guy C, Dunger DB, Dayan CM, Powrie J, Lorenc A, Peakman M.

Diabet Med. 2017 Mar;34(3):419-425. doi: 10.1111/dme.13153. Epub 2016 May 30.

PMID:
27151105
13.

Thyroxine replacement: a clinical endocrinologist's viewpoint.

Eligar V, Taylor PN, Okosieme OE, Leese GP, Dayan CM.

Ann Clin Biochem. 2016 Jul;53(Pt 4):421-33. doi: 10.1177/0004563216642255. Epub 2016 Apr 28. Review.

PMID:
27126268
14.

Microneedle delivery of autoantigen for immunotherapy in type 1 diabetes.

Zhao X, Birchall JC, Coulman SA, Tatovic D, Singh RK, Wen L, Wong FS, Dayan CM, Hanna SJ.

J Control Release. 2016 Feb 10;223:178-187. doi: 10.1016/j.jconrel.2015.12.040. Epub 2015 Dec 29.

15.

Paradoxical Relationship Between Body Mass Index and Thyroid Hormone Levels: A Study Using Mendelian Randomization.

Taylor PN, Richmond R, Davies N, Sayers A, Stevenson K, Woltersdorf W, Taylor A, Groom A, Northstone K, Ring S, Okosieme O, Rees A, Nitsch D, Williams GR, Smith GD, Gregory JW, Timpson NJ, Tobias JH, Dayan CM.

J Clin Endocrinol Metab. 2016 Feb;101(2):730-8. doi: 10.1210/jc.2015-3505. Epub 2015 Nov 23.

16.

Reversal of Pathological Features of Graves' Orbitopathy by Activation of Forkhead Transcription Factors, FOXOs.

Zhang L, Ji QH, Ruge F, Lane C, Morris D, Tee AR, Dayan CM, Ludgate M.

J Clin Endocrinol Metab. 2016 Jan;101(1):114-22. doi: 10.1210/jc.2015-2932. Epub 2015 Oct 26.

PMID:
26502358
17.

Future Research in Graves' Orbitopathy: From Priority Setting to Trial Design Through Patient and Public Involvement.

Perros P, Dayan CM, Dickinson AJ, Ezra DG, Hickey JL, Hintschisch C, Kahaly G, Lazarus JH, Ludgate M, Bartès B, MacEwen CJ, Mitchell AL, Morris D, O'Connor N, Pearce SH, Rose GE, Salvi M, Wiersinga WM, Williamson A; Thyroid Eye Disease Amsterdam Declaration Implementation Group UK; European Group on Graves’ Orbitopathy.

Thyroid. 2015 Nov;25(11):1181-4. doi: 10.1089/thy.2015.0222. Epub 2015 Oct 14. No abstract available.

18.

Topical steroid therapy induces pro-tolerogenic changes in Langerhans cells in human skin.

Ali MA, Thrower SL, Hanna SJ, Coulman SA, Birchall JC, Wong FS, Dayan CM, Tatovic D.

Immunology. 2015 Nov;146(3):411-22. doi: 10.1111/imm.12518. Epub 2015 Sep 13.

19.

The sodium iodide symporter is unlikely to be a thyroid/breast shared antigen.

Muller I, Zhang L, Giani C, Dayan CM, Ludgate ME, Grennan-Jones F.

J Endocrinol Invest. 2016 Mar;39(3):323-31. doi: 10.1007/s40618-015-0368-6. Epub 2015 Aug 8.

PMID:
26253711
20.

Genetic abnormalities in thyroid hormone deiodinases.

Taylor PN, Peeters R, Dayan CM.

Curr Opin Endocrinol Diabetes Obes. 2015 Oct;22(5):402-6. doi: 10.1097/MED.0000000000000180. Review.

PMID:
26192703
21.

Fine-Needle Aspiration Biopsy of the Lymph Node: A Novel Tool for the Monitoring of Immune Responses after Skin Antigen Delivery.

Tatovic D, Young P, Kochba E, Levin Y, Wong FS, Dayan CM.

J Immunol. 2015 Jul 1;195(1):386-92. doi: 10.4049/jimmunol.1500364. Epub 2015 May 29.

22.

Erratum: Whole-genome sequence-based analysis of thyroid function.

Taylor PN, Porcu E, Chew S, Campbell PJ, Traglia M, Brown SJ, Mullin BH, Shihab HA, Min J, Walter K, Memari Y, Huang J, Barnes MR, Beilby JP, Charoen P, Danecek P, Dudbridge F, Forgetta V, Greenwood C, Grundberg E, Johnson AD, Hui J, Lim EM, McCarthy S, Muddyman D, Panicker V, Perry JR, Bell JT, Yuan W, Relton C, Gaunt T, Schlessinger D, Abecasis G, Cucca F, Surdulescu GL, Woltersdorf W, Zeggini E, Zheng HF, Toniolo D, Dayan CM, Naitza S, Walsh JP, Spector T, Smith GD, Durbin R, Richards JB, Sanna S, Soranzo N, Timpson NJ, Wilson SG; UK10K Consortium.

Nat Commun. 2015 May 20;6:7172. doi: 10.1038/ncomms8172. No abstract available.

23.

Bariatric surgery in morbidly obese insulin resistant humans normalises insulin signalling but not insulin-stimulated glucose disposal.

Chen MZ, Hudson CA, Vincent EE, de Berker DA, May MT, Hers I, Dayan CM, Andrews RC, Tavaré JM.

PLoS One. 2015 Apr 13;10(4):e0120084. doi: 10.1371/journal.pone.0120084. eCollection 2015.

24.

Evidence for a persistent, major excess in all cause admissions to hospital in children with type-1 diabetes: results from a large Welsh national matched community cohort study.

Sayers A, Thayer D, Harvey JN, Luzio S, Atkinson MD, French R, Warner JT, Dayan CM, Wong SF, Gregory JW.

BMJ Open. 2015 Apr 13;5(4):e005644. doi: 10.1136/bmjopen-2014-005644.

25.

Management of patients with Graves' orbitopathy: initial assessment, management outside specialised centres and referral pathways.

Perros P, Dayan CM, Dickinson AJ, Ezra D, Estcourt S, Foley P, Hickey J, Lazarus JH, MacEwen CJ, McLaren J, Rose GE, Uddin J, Vaidya B.

Clin Med (Lond). 2015 Apr;15(2):173-8. doi: 10.7861/clinmedicine.15-2-173.

PMID:
25824071
26.

Whole-genome sequence-based analysis of thyroid function.

Taylor PN, Porcu E, Chew S, Campbell PJ, Traglia M, Brown SJ, Mullin BH, Shihab HA, Min J, Walter K, Memari Y, Huang J, Barnes MR, Beilby JP, Charoen P, Danecek P, Dudbridge F, Forgetta V, Greenwood C, Grundberg E, Johnson AD, Hui J, Lim EM, McCarthy S, Muddyman D, Panicker V, Perry JR, Bell JT, Yuan W, Relton C, Gaunt T, Schlessinger D, Abecasis G, Cucca F, Surdulescu GL, Woltersdorf W, Zeggini E, Zheng HF, Toniolo D, Dayan CM, Naitza S, Walsh JP, Spector T, Davey Smith G, Durbin R, Richards JB, Sanna S, Soranzo N, Timpson NJ, Wilson SG; UK0K Consortium.

Nat Commun. 2015 Mar 6;6:5681. doi: 10.1038/ncomms6681. Erratum in: Nat Commun. 2015;6:7172. Lotchkova, Valentina [corrected to Iotchkova, Valentina]; Quai, Michael A [corrected to Quail, Michael].

27.

Treatment of borderline elevated thyrotropin levels--reply.

Taylor PN, Okosieme OE, Dayan CM.

JAMA Intern Med. 2015 Mar;175(3):466-7. doi: 10.1001/jamainternmed.2014.7862. No abstract available.

PMID:
25730574
28.

The second wave of the Controlled Antenatal Thyroid Screening (CATS II) study: the cognitive assessment protocol.

Hales C, Channon S, Taylor PN, Draman MS, Muller I, Lazarus J, Paradice R, Rees A, Shillabeer D, Gregory JW, Dayan CM, Ludgate M.

BMC Endocr Disord. 2014 Dec 12;14:95. doi: 10.1186/1472-6823-14-95.

29.

β-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure.

Skowera A, Ladell K, McLaren JE, Dolton G, Matthews KK, Gostick E, Kronenberg-Versteeg D, Eichmann M, Knight RR, Heck S, Powrie J, Bingley PJ, Dayan CM, Miles JJ, Sewell AK, Price DA, Peakman M.

Diabetes. 2015 Mar;64(3):916-925. doi: 10.2337/db14-0332. Epub 2014 Sep 23.

30.

TSH levels and risk of miscarriage in women on long-term levothyroxine: a community-based study.

Taylor PN, Minassian C, Rehman A, Iqbal A, Draman MS, Hamilton W, Dunlop D, Robinson A, Vaidya B, Lazarus JH, Thomas S, Dayan CM, Okosieme OE.

J Clin Endocrinol Metab. 2014 Oct;99(10):3895-902. doi: 10.1210/jc.2014-1954. Epub 2014 Jul 24.

PMID:
25057882
31.

Maternal perchlorate levels in women with borderline thyroid function during pregnancy and the cognitive development of their offspring: data from the Controlled Antenatal Thyroid Study.

Taylor PN, Okosieme OE, Murphy R, Hales C, Chiusano E, Maina A, Joomun M, Bestwick JP, Smyth P, Paradice R, Channon S, Braverman LE, Dayan CM, Lazarus JH, Pearce EN.

J Clin Endocrinol Metab. 2014 Nov;99(11):4291-8. doi: 10.1210/jc.2014-1901. Epub 2014 Jul 24.

PMID:
25057878
32.

Description and evaluation of the first national patient and public involvement day for thyroid eye disease in the United Kingdom.

Smith HB, Porteous C, Bunce C, Bonstein K, Hickey J, Dayan CM, Adams G, Rose GE, Ezra DG.

Thyroid. 2014 Sep;24(9):1400-6. doi: 10.1089/thy.2014.0200. Epub 2014 Jul 21.

33.

Sedentary time and markers of inflammation in people with newly diagnosed type 2 diabetes.

Falconer CL, Cooper AR, Walhin JP, Thompson D, Page AS, Peters TJ, Montgomery AA, Sharp DJ, Dayan CM, Andrews RC.

Nutr Metab Cardiovasc Dis. 2014 Sep;24(9):956-62. doi: 10.1016/j.numecd.2014.03.009. Epub 2014 Apr 26.

34.

Hypothyroidism and depression.

Dayan CM, Panicker V.

Eur Thyroid J. 2013 Sep;2(3):168-79. doi: 10.1159/000353777. Epub 2013 Aug 27. Review.

35.

Long-term outcome in patients with severe alcoholic hepatitis can be reliably determined using an in vitro measure of steroid sensitivity.

Dhanda AD, di Mambro AJ, Hunt VL, McCune CA, Dayan CM, Dick AD, Lee RW, Collins PL.

Hepatology. 2015 Mar;61(3):1099. doi: 10.1002/hep.27211. Epub 2014 Jul 31. No abstract available.

PMID:
24811769
36.

Possible targets for nonimmunosuppressive therapy of Graves' orbitopathy.

Zhang L, Grennan-Jones F, Draman MS, Lane C, Morris D, Dayan CM, Tee AR, Ludgate M.

J Clin Endocrinol Metab. 2014 Jul;99(7):E1183-90. doi: 10.1210/jc.2013-4182. Epub 2014 Apr 23.

PMID:
24758182
37.

Efficacy and safety of low-dose otelixizumab anti-CD3 monoclonal antibody in preserving C-peptide secretion in adolescent type 1 diabetes: DEFEND-2, a randomized, placebo-controlled, double-blind, multi-centre study.

Ambery P, Donner TW, Biswas N, Donaldson J, Parkin J, Dayan CM.

Diabet Med. 2014 Apr;31(4):399-402. doi: 10.1111/dme.12361. Epub 2013 Dec 6.

PMID:
24236828
38.

Does thyroid peroxidase provide an antigenic link between thyroid autoimmunity and breast cancer?

Muller I, Giani C, Zhang L, Grennan-Jones FA, Fiore E, Belardi V, Rosellini V, Funel N, Campani D, Giustarini E, Lewis MD, Bakhsh AD, Roncella M, Ghilli M, Vitti P, Dayan CM, Ludgate ME.

Int J Cancer. 2014 Apr 1;134(7):1706-14. doi: 10.1002/ijc.28493. Epub 2013 Oct 15.

39.

Therapy of endocrine disease: Impact of iodine supplementation in mild-to-moderate iodine deficiency: systematic review and meta-analysis.

Taylor PN, Okosieme OE, Dayan CM, Lazarus JH.

Eur J Endocrinol. 2013 Oct 2;170(1):R1-R15. doi: 10.1530/EJE-13-0651. Print 2014 Jan. Review.

40.

Clinical review: A review of the clinical consequences of variation in thyroid function within the reference range.

Taylor PN, Razvi S, Pearce SH, Dayan CM.

J Clin Endocrinol Metab. 2013 Sep;98(9):3562-71. doi: 10.1210/jc.2013-1315. Epub 2013 Jul 3. Review.

PMID:
23824418
41.

Pancreatic volume is reduced in adult patients with recently diagnosed type 1 diabetes.

Williams AJ, Thrower SL, Sequeiros IM, Ward A, Bickerton AS, Triay JM, Callaway MP, Dayan CM.

J Clin Endocrinol Metab. 2012 Nov;97(11):E2109-13. doi: 10.1210/jc.2012-1815. Epub 2012 Aug 9.

PMID:
22879632
42.

Amiodarone-induced thyrotoxicosis, an overview of UK management.

Raghavan RP, Taylor PN, Bhake R, Vaidya B, Martino E, Bartalena L, Dayan CM, Bradley K.

Clin Endocrinol (Oxf). 2012 Dec;77(6):936-7. doi: 10.1111/j.1365-2265.2012.04435.x. No abstract available.

PMID:
22578004
43.

Basiliximab does not increase efficacy of corticosteroids in patients with steroid-refractory ulcerative colitis.

Sands BE, Sandborn WJ, Creed TJ, Dayan CM, Dhanda AD, Van Assche GA, Greguš M, Sood A, Choudhuri G, Stempien MJ, Levitt D, Probert CS.

Gastroenterology. 2012 Aug;143(2):356-64.e1. doi: 10.1053/j.gastro.2012.04.043. Epub 2012 Apr 28.

PMID:
22549092
44.

Circulating preproinsulin signal peptide-specific CD8 T cells restricted by the susceptibility molecule HLA-A24 are expanded at onset of type 1 diabetes and kill β-cells.

Kronenberg D, Knight RR, Estorninho M, Ellis RJ, Kester MG, de Ru A, Eichmann M, Huang GC, Powrie J, Dayan CM, Skowera A, van Veelen PA, Peakman M.

Diabetes. 2012 Jul;61(7):1752-9. doi: 10.2337/db11-1520. Epub 2012 Apr 20.

45.

Sedentary time, breaks in sedentary time and metabolic variables in people with newly diagnosed type 2 diabetes.

Cooper AR, Sebire S, Montgomery AA, Peters TJ, Sharp DJ, Jackson N, Fitzsimons K, Dayan CM, Andrews RC.

Diabetologia. 2012 Mar;55(3):589-99. doi: 10.1007/s00125-011-2408-x. Epub 2011 Dec 14.

PMID:
22167127
46.

Adipose tissue depot-specific differences in the regulation of hyaluronan production of relevance to Graves' orbitopathy.

Zhang L, Grennan-Jones F, Lane C, Rees DA, Dayan CM, Ludgate M.

J Clin Endocrinol Metab. 2012 Feb;97(2):653-62. doi: 10.1210/jc.2011-1299. Epub 2011 Dec 7.

PMID:
22162480
47.

Orbital decompression for Graves' orbitopathy in England.

Perros P, Chandler T, Dayan CM, Dickinson AJ, Foley P, Hickey J, Macewen CJ, Lazarus JH, McLaren J, Rose GE, Uddin JM, Vaidya B.

Eye (Lond). 2012 Mar;26(3):434-7. doi: 10.1038/eye.2011.323. Epub 2011 Dec 9.

48.

Immunology of Diabetes Society T-Cell Workshop: HLA class I tetramer-directed epitope validation initiative T-Cell Workshop Report-HLA Class I Tetramer Validation Initiative.

Mallone R, Scotto M, Janicki CN, James EA, Fitzgerald-Miller L, Wagner R, Gottlieb P, Thorpe J, Jospe N, Durinovic-Bellò I, Boitard C, Lou O, Dayan CM, Wong FS; T-Cell Workshop Committee, Immunology of Diabetes Society.

Diabetes Metab Res Rev. 2011 Nov;27(8):720-6. doi: 10.1002/dmrr.1243.

PMID:
22069251
49.

Smoking and strabismus surgery in patients with thyroid eye disease.

Rajendram R, Bunce C, Adams GG, Dayan CM, Rose GE.

Ophthalmology. 2011 Dec;118(12):2493-7. doi: 10.1016/j.ophtha.2011.06.003. Epub 2011 Aug 27.

PMID:
21872937
50.

Diet or diet plus physical activity versus usual care in patients with newly diagnosed type 2 diabetes: the Early ACTID randomised controlled trial.

Andrews RC, Cooper AR, Montgomery AA, Norcross AJ, Peters TJ, Sharp DJ, Jackson N, Fitzsimons K, Bright J, Coulman K, England CY, Gorton J, McLenaghan A, Paxton E, Polet A, Thompson C, Dayan CM.

Lancet. 2011 Jul 9;378(9786):129-39. doi: 10.1016/S0140-6736(11)60442-X. Epub 2011 Jun 24.

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