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Items: 1 to 50 of 61

1.

High-titer antibody depletion enhances discovery of diverse serum antibody specificities.

Bozekowski JD, Graham AJ, Daugherty PS.

J Immunol Methods. 2018 Apr;455:1-9. doi: 10.1016/j.jim.2018.01.003. Epub 2018 Jan 24.

2.

Prediction of antibody structural epitopes via random peptide library screening and next generation sequencing.

Ibsen KN, Daugherty PS.

J Immunol Methods. 2017 Dec;451:28-36. doi: 10.1016/j.jim.2017.08.004. Epub 2017 Aug 18.

PMID:
28827189
3.

Emerging technologies for protease engineering: New tools to clear out disease.

Guerrero JL, Daugherty PS, O'Malley MA.

Biotechnol Bioeng. 2017 Jan;114(1):33-38. doi: 10.1002/bit.26066. Epub 2016 Aug 17. Review.

PMID:
27497426
4.

Identification of disease-specific motifs in the antibody specificity repertoire via next-generation sequencing.

Pantazes RJ, Reifert J, Bozekowski J, Ibsen KN, Murray JA, Daugherty PS.

Sci Rep. 2016 Aug 2;6:30312. doi: 10.1038/srep30312.

5.

Transglutaminase is a Critical Link Between Inflammation and Hypertension.

Luo R, Liu C, Elliott SE, Wang W, Parchim N, Iriyama T, Daugherty PS, Tao L, Eltzschig HK, Blackwell SC, Sibai BM, Kellems RE, Xia Y.

J Am Heart Assoc. 2016 Jun 30;5(7). pii: e003730. doi: 10.1161/JAHA.116.003730.

6.

A pre-eclampsia-associated Epstein-Barr virus antibody cross-reacts with placental GPR50.

Elliott SE, Parchim NF, Kellems RE, Xia Y, Soffici AR, Daugherty PS.

Clin Immunol. 2016 Jul;168:64-71. doi: 10.1016/j.clim.2016.05.002. Epub 2016 May 12.

PMID:
27181993
7.

Intracellular FRET-based Screen for Redesigning the Specificity of Secreted Proteases.

Guerrero JL, O'Malley MA, Daugherty PS.

ACS Chem Biol. 2016 Apr 15;11(4):961-70. doi: 10.1021/acschembio.5b01051. Epub 2016 Jan 14.

PMID:
26730612
8.

Elevated Transglutaminase Activity Triggers Angiotensin Receptor Activating Autoantibody Production and Pathophysiology of Preeclampsia.

Liu C, Luo R, Elliott SE, Wang W, Parchim NF, Iriyama T, Daugherty PS, Blackwell SC, Sibai BM, Kellems RE, Xia Y.

J Am Heart Assoc. 2015 Dec 16;4(12). pii: e002323. doi: 10.1161/JAHA.115.002323.

9.

De novo discovery of bioactive cyclic peptides using bacterial display and flow cytometry.

Shivange AV, Daugherty PS.

Methods Mol Biol. 2015;1248:139-53. doi: 10.1007/978-1-4939-2020-4_10. Review.

PMID:
25616331
10.

Letter: nonresponsive coeliac disease and evaluation of the strictness of a gluten-free diet - authors' reply.

Kaukinen K, Daugherty PS.

Aliment Pharmacol Ther. 2014 May;39(10):1242. doi: 10.1111/apt.12729. No abstract available.

11.

Characterization of antibody specificities associated with preeclampsia.

Elliott SE, Parchim NF, Liu C, Xia Y, Kellems RE, Soffici AR, Daugherty PS.

Hypertension. 2014 May;63(5):1086-93. doi: 10.1161/HYPERTENSIONAHA.113.02362. Epub 2014 Jan 20.

12.

Persistence of elevated deamidated gliadin peptide antibodies on a gluten-free diet indicates nonresponsive coeliac disease.

Spatola BN, Kaukinen K, Collin P, Mäki M, Kagnoff MF, Daugherty PS.

Aliment Pharmacol Ther. 2014 Feb;39(4):407-17. doi: 10.1111/apt.12603. Epub 2014 Jan 6.

13.

A novel quantitative kinase assay using bacterial surface display and flow cytometry.

Henriques ST, Thorstholm L, Huang YH, Getz JA, Daugherty PS, Craik DJ.

PLoS One. 2013 Nov 15;8(11):e80474. doi: 10.1371/journal.pone.0080474. eCollection 2013.

14.

Antibody biomarker discovery through in vitro directed evolution of consensus recognition epitopes.

Ballew JT, Murray JA, Collin P, Mäki M, Kagnoff MF, Kaukinen K, Daugherty PS.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19330-5. doi: 10.1073/pnas.1314792110. Epub 2013 Nov 12.

15.

Tumor-specific activation of an EGFR-targeting probody enhances therapeutic index.

Desnoyers LR, Vasiljeva O, Richardson JH, Yang A, Menendez EE, Liang TW, Wong C, Bessette PH, Kamath K, Moore SJ, Sagert JG, Hostetter DR, Han F, Gee J, Flandez J, Markham K, Nguyen M, Krimm M, Wong KR, Liu S, Daugherty PS, West JW, Lowman HB.

Sci Transl Med. 2013 Oct 16;5(207):207ra144. doi: 10.1126/scitranslmed.3006682.

16.

Biochemical and structural characterization of SplD protease from Staphylococcus aureus.

Zdzalik M, Kalinska M, Wysocka M, Stec-Niemczyk J, Cichon P, Stach N, Gruba N, Stennicke HR, Jabaiah A, Markiewicz M, Kedracka-Krok S, Wladyka B, Daugherty PS, Lesner A, Rolka K, Dubin A, Potempa J, Dubin G.

PLoS One. 2013 Oct 9;8(10):e76812. doi: 10.1371/journal.pone.0076812. eCollection 2013.

17.

Amyloid β peptide cleavage by kallikrein 7 attenuates fibril growth and rescues neurons from Aβ-mediated toxicity in vitro.

Shropshire TD, Reifert J, Rajagopalan S, Baker D, Feinstein SC, Daugherty PS.

Biol Chem. 2014 Jan;395(1):109-18. doi: 10.1515/hsz-2013-0230.

PMID:
23989112
18.

Design of a cyclotide antagonist of neuropilin-1 and -2 that potently inhibits endothelial cell migration.

Getz JA, Cheneval O, Craik DJ, Daugherty PS.

ACS Chem Biol. 2013;8(6):1147-54. doi: 10.1021/cb4000585. Epub 2013 Apr 12.

PMID:
23537207
19.

Antibody repertoire profiling using bacterial display identifies reactivity signatures of celiac disease.

Spatola BN, Murray JA, Kagnoff M, Kaukinen K, Daugherty PS.

Anal Chem. 2013 Jan 15;85(2):1215-22. doi: 10.1021/ac303201d. Epub 2012 Dec 21.

20.

Identification of protease exosite-interacting peptides that enhance substrate cleavage kinetics.

Jabaiah AM, Getz JA, Witkowski WA, Hardy JA, Daugherty PS.

Biol Chem. 2012 Sep;393(9):933-41. doi: 10.1515/hsz-2012-0162.

21.

OS042. Discovery and characterization of antibody biomarkers ofpre-eclampsia and reagents for their detection.

Elliott SE, Soffici AR, Daugherty PS.

Pregnancy Hypertens. 2012 Jul;2(3):199-200. doi: 10.1016/j.preghy.2012.04.043. Epub 2012 Jun 13.

PMID:
26105256
22.

Site-specific targeting of antibody activity in vivo mediated by disease-associated proteases.

Erster O, Thomas JM, Hamzah J, Jabaiah AM, Getz JA, Schoep TD, Hall SS, Ruoslahti E, Daugherty PS.

J Control Release. 2012 Aug 10;161(3):804-12. doi: 10.1016/j.jconrel.2012.05.035. Epub 2012 May 23.

23.

Peptide discovery using bacterial display and flow cytometry.

Getz JA, Schoep TD, Daugherty PS.

Methods Enzymol. 2012;503:75-97. doi: 10.1016/B978-0-12-396962-0.00004-5.

PMID:
22230566
24.

Substrate specificity of Staphylococcus aureus cysteine proteases--Staphopains A, B and C.

Kalińska M, Kantyka T, Greenbaum DC, Larsen KS, Władyka B, Jabaiah A, Bogyo M, Daugherty PS, Wysocka M, Jaros M, Lesner A, Rolka K, Schaschke N, Stennicke H, Dubin A, Potempa J, Dubin G.

Biochimie. 2012 Feb;94(2):318-27. doi: 10.1016/j.biochi.2011.07.020. Epub 2011 Jul 23.

PMID:
21802486
25.

Protease-resistant peptide ligands from a knottin scaffold library.

Getz JA, Rice JJ, Daugherty PS.

ACS Chem Biol. 2011 Aug 19;6(8):837-44. doi: 10.1021/cb200039s. Epub 2011 Jun 16.

26.

Directed evolution of protease beacons that enable sensitive detection of endogenous MT1-MMP activity in tumor cell lines.

Jabaiah A, Daugherty PS.

Chem Biol. 2011 Mar 25;18(3):392-401. doi: 10.1016/j.chembiol.2010.12.017.

27.

Exploiting bacterial peptide display technology to engineer biomaterials for neural stem cell culture.

Little LE, Dane KY, Daugherty PS, Healy KE, Schaffer DV.

Biomaterials. 2011 Feb;32(6):1484-94. doi: 10.1016/j.biomaterials.2010.10.032. Epub 2010 Dec 3.

28.

Detection of telomerase activity in high concentration of cell lysates using primer-modified gold nanoparticles.

Xiao Y, Dane KY, Uzawa T, Csordas A, Qian J, Soh HT, Daugherty PS, Lagally ET, Heeger AJ, Plaxco KW.

J Am Chem Soc. 2010 Nov 3;132(43):15299-307. doi: 10.1021/ja106513f.

PMID:
20932008
29.

Evolutionary optimization of peptide substrates for proteases that exhibit rapid hydrolysis kinetics.

Boulware KT, Jabaiah A, Daugherty PS.

Biotechnol Bioeng. 2010 Jun 15;106(3):339-46. doi: 10.1002/bit.22693.

PMID:
20148412
30.

A novel matrix metalloprotease-like enzyme (karilysin) of the periodontal pathogen Tannerella forsythia ATCC 43037.

Karim AY, Kulczycka M, Kantyka T, Dubin G, Jabaiah A, Daugherty PS, Thogersen IB, Enghild JJ, Nguyen KA, Potempa J.

Biol Chem. 2010 Jan;391(1):105-17. doi: 10.1515/BC.2010.009.

31.

Bacterial display enables efficient and quantitative peptide affinity maturation.

Kenrick SA, Daugherty PS.

Protein Eng Des Sel. 2010 Jan;23(1):9-17. doi: 10.1093/protein/gzp065.

32.

Proligands with protease-regulated binding activity identified from cell-displayed prodomain libraries.

Thomas JM, Daugherty PS.

Protein Sci. 2009 Oct;18(10):2053-9. doi: 10.1002/pro.217.

33.
34.

Cell surface profiling with peptide libraries yields ligand arrays that classify breast tumor subtypes.

Dane KY, Gottstein C, Daugherty PS.

Mol Cancer Ther. 2009 May;8(5):1312-8. doi: 10.1158/1535-7163.MCT-08-1105. Epub 2009 May 5.

35.

Structural and functional characterization of SplA, an exclusively specific protease of Staphylococcus aureus.

Stec-Niemczyk J, Pustelny K, Kisielewska M, Bista M, Boulware KT, Stennicke HR, Thogersen IB, Daugherty PS, Enghild JJ, Baczynski K, Popowicz GM, Dubin A, Potempa J, Dubin G.

Biochem J. 2009 May 1;419(3):555-64. doi: 10.1042/BJ20081351.

PMID:
19175361
36.

Multitarget dielectrophoresis activated cell sorter.

Kim U, Qian J, Kenrick SA, Daugherty PS, Soh HT.

Anal Chem. 2008 Nov 15;80(22):8656-61. doi: 10.1021/ac8015938. Epub 2008 Oct 22.

37.

Directed evolution of a biterminal bacterial display scaffold enhances the display of diverse peptides.

Rice JJ, Daugherty PS.

Protein Eng Des Sel. 2008 Jul;21(7):435-42. doi: 10.1093/protein/gzn020. Epub 2008 May 13.

38.

Enzymatic activity of the Staphylococcus aureus SplB serine protease is induced by substrates containing the sequence Trp-Glu-Leu-Gln.

Dubin G, Stec-Niemczyk J, Kisielewska M, Pustelny K, Popowicz GM, Bista M, Kantyka T, Boulware KT, Stennicke HR, Czarna A, Phopaisarn M, Daugherty PS, Thøgersen IB, Enghild JJ, Thornberry N, Dubin A, Potempa J.

J Mol Biol. 2008 May 30;379(2):343-56. doi: 10.1016/j.jmb.2008.03.059. Epub 2008 Apr 3.

PMID:
18448121
39.

Selection of mammalian cells based on their cell-cycle phase using dielectrophoresis.

Kim U, Shu CW, Dane KY, Daugherty PS, Wang JY, Soh HT.

Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20708-12. Epub 2007 Dec 19.

40.

Protein engineering with bacterial display.

Daugherty PS.

Curr Opin Struct Biol. 2007 Aug;17(4):474-80. Epub 2007 Aug 28. Review.

PMID:
17728126
41.

Identification of peptide ligands facilitating nanoparticle attachment to erythrocytes.

Hall SS, Mitragotri S, Daugherty PS.

Biotechnol Prog. 2007 May-Jun;23(3):749-54. Epub 2007 May 1.

PMID:
17469847
42.

Microfluidic library screening for mapping antibody epitopes.

Bessette PH, Hu X, Soh HT, Daugherty PS.

Anal Chem. 2007 Mar 1;79(5):2174-8. Epub 2007 Jan 26.

PMID:
17253874
43.

Microfluidic protein detection through genetically engineered bacterial cells.

Oh SH, Lee SH, Kenrick SA, Daugherty PS, Soh HT.

J Proteome Res. 2006 Dec;5(12):3433-7.

PMID:
17137345
44.

Intracellular protein interaction mapping with FRET hybrids.

You X, Nguyen AW, Jabaiah A, Sheff MA, Thorn KS, Daugherty PS.

Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18458-63. Epub 2006 Nov 27.

45.

Blue fluorescent proteins with enhanced brightness and photostability from a structurally targeted library.

Mena MA, Treynor TP, Mayo SL, Daugherty PS.

Nat Biotechnol. 2006 Dec;24(12):1569-71. Epub 2006 Nov 19.

PMID:
17115054
46.

Protease specificity determination by using cellular libraries of peptide substrates (CLiPS).

Boulware KT, Daugherty PS.

Proc Natl Acad Sci U S A. 2006 May 16;103(20):7583-8. Epub 2006 May 3.

47.

Bacterial display using circularly permuted outer membrane protein OmpX yields high affinity peptide ligands.

Rice JJ, Schohn A, Bessette PH, Boulware KT, Daugherty PS.

Protein Sci. 2006 Apr;15(4):825-36.

48.

Isolation of cell specific peptide ligands using fluorescent bacterial display libraries.

Dane KY, Chan LA, Rice JJ, Daugherty PS.

J Immunol Methods. 2006 Feb 20;309(1-2):120-9. Epub 2006 Jan 11.

PMID:
16448666
49.

Enzymatic synthesis of layered titanium phosphates at low temperature and neutral pH by cell-surface display of silicatein-alpha.

Curnow P, Bessette PH, Kisailus D, Murr MM, Daugherty PS, Morse DE.

J Am Chem Soc. 2005 Nov 16;127(45):15749-55.

PMID:
16277517
50.

Automated design of degenerate codon libraries.

Mena MA, Daugherty PS.

Protein Eng Des Sel. 2005 Dec;18(12):559-61. Epub 2005 Oct 20.

PMID:
16239261

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