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Items: 16

1.

Metabolomics and Gene Expression Analysis Reveal Down-regulation of the Citric Acid (TCA) Cycle in Non-diabetic CKD Patients.

Hallan S, Afkarian M, Zelnick LR, Kestenbaum B, Sharma S, Saito R, Darshi M, Barding G, Raftery D, Ju W, Kretzler M, Sharma K, de Boer IH.

EBioMedicine. 2017 Dec;26:68-77. doi: 10.1016/j.ebiom.2017.10.027. Epub 2017 Oct 31.

2.

Sub-mitochondrial localization of the genetic-tagged mitochondrial intermembrane space-bridging components Mic19, Mic60 and Sam50.

Sastri M, Darshi M, Mackey M, Ramachandra R, Ju S, Phan S, Adams S, Stein K, Douglas CR, Kim JJ, Ellisman MH, Taylor SS, Perkins GA.

J Cell Sci. 2017 Oct 1;130(19):3248-3260. doi: 10.1242/jcs.201400. Epub 2017 Aug 14.

PMID:
28808085
3.

AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent of adiponectin.

Börgeson E, Wallenius V, Syed GH, Darshi M, Lantero Rodriguez J, Biörserud C, Ragnmark Ek M, Björklund P, Quiding-Järbrink M, Fändriks L, Godson C, Sharma K.

Diabetologia. 2017 Apr;60(4):729-739. doi: 10.1007/s00125-017-4211-9. Epub 2017 Feb 10.

PMID:
28188334
4.

Systems biology analysis reveals role of MDM2 in diabetic nephropathy.

Saito R, Rocanin-Arjo A, You YH, Darshi M, Van Espen B, Miyamoto S, Pham J, Pu M, Romoli S, Natarajan L, Ju W, Kretzler M, Nelson R, Ono K, Thomasova D, Mulay SR, Ideker T, D'Agati V, Beyret E, Belmonte JC, Anders HJ, Sharma K.

JCI Insight. 2016 Oct 20;1(17):e87877.

5.

Tissue-specific metabolic reprogramming drives nutrient flux in diabetic complications.

Sas KM, Kayampilly P, Byun J, Nair V, Hinder LM, Hur J, Zhang H, Lin C, Qi NR, Michailidis G, Groop PH, Nelson RG, Darshi M, Sharma K, Schelling JR, Sedor JR, Pop-Busui R, Weinberg JM, Soleimanpour SA, Abcouwer SF, Gardner TW, Burant CF, Feldman EL, Kretzler M, Brosius FC 3rd, Pennathur S.

JCI Insight. 2016 Sep 22;1(15):e86976.

6.

Metabolomics in Diabetic Kidney Disease: Unraveling the Biochemistry of a Silent Killer.

Darshi M, Van Espen B, Sharma K.

Am J Nephrol. 2016;44(2):92-103. doi: 10.1159/000447954. Epub 2016 Jul 14. Review.

7.

Mass Spectrometry Imaging Reveals Elevated Glomerular ATP/AMP in Diabetes/obesity and Identifies Sphingomyelin as a Possible Mediator.

Miyamoto S, Hsu CC, Hamm G, Darshi M, Diamond-Stanic M, Declèves AE, Slater L, Pennathur S, Stauber J, Dorrestein PC, Sharma K.

EBioMedicine. 2016 May;7:121-34. doi: 10.1016/j.ebiom.2016.03.033. Epub 2016 Mar 28.

8.

Mechanisms of cyclic AMP/protein kinase A- and glucocorticoid-mediated apoptosis using S49 lymphoma cells as a model system.

Keshwani MM, Kanter JR, Ma Y, Wilderman A, Darshi M, Insel PA, Taylor SS.

Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12681-6. doi: 10.1073/pnas.1516057112. Epub 2015 Sep 28.

9.

Uniform nomenclature for the mitochondrial contact site and cristae organizing system.

Pfanner N, van der Laan M, Amati P, Capaldi RA, Caudy AA, Chacinska A, Darshi M, Deckers M, Hoppins S, Icho T, Jakobs S, Ji J, Kozjak-Pavlovic V, Meisinger C, Odgren PR, Park SK, Rehling P, Reichert AS, Sheikh MS, Taylor SS, Tsuchida N, van der Bliek AM, van der Klei IJ, Weissman JS, Westermann B, Zha J, Neupert W, Nunnari J.

J Cell Biol. 2014 Mar 31;204(7):1083-6. doi: 10.1083/jcb.201401006.

10.

Quantitative proteomic and functional analysis of liver mitochondria from high fat diet (HFD) diabetic mice.

Guo Y, Darshi M, Ma Y, Perkins GA, Shen Z, Haushalter KJ, Saito R, Chen A, Lee YS, Patel HH, Briggs SP, Ellisman MH, Olefsky JM, Taylor SS.

Mol Cell Proteomics. 2013 Dec;12(12):3744-58. doi: 10.1074/mcp.M113.027441. Epub 2013 Sep 12.

11.

A kinase interacting protein (AKIP1) is a key regulator of cardiac stress.

Sastri M, Haushalter KJ, Panneerselvam M, Chang P, Fridolfsson H, Finley JC, Ng D, Schilling JM, Miyanohara A, Day ME, Hakozaki H, Petrosyan S, Koller A, King CC, Darshi M, Blumenthal DK, Ali SS, Roth DM, Patel HH, Taylor SS.

Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):E387-96. doi: 10.1073/pnas.1221670110. Epub 2013 Jan 14.

12.

Targeting and import mechanism of coiled-coil helix coiled-coil helix domain-containing protein 3 (ChChd3) into the mitochondrial intermembrane space.

Darshi M, Trinh KN, Murphy AN, Taylor SS.

J Biol Chem. 2012 Nov 16;287(47):39480-91. doi: 10.1074/jbc.M112.387696. Epub 2012 Sep 27.

13.

ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function.

Darshi M, Mendiola VL, Mackey MR, Murphy AN, Koller A, Perkins GA, Ellisman MH, Taylor SS.

J Biol Chem. 2011 Jan 28;286(4):2918-32. doi: 10.1074/jbc.M110.171975. Epub 2010 Nov 16.

14.

Membrane protein stoichiometry determined from the step-wise photobleaching of dye-labelled subunits.

Das SK, Darshi M, Cheley S, Wallace MI, Bayley H.

Chembiochem. 2007 Jun 18;8(9):994-9. No abstract available.

PMID:
17503420
15.

Identification of ChChd3 as a novel substrate of the cAMP-dependent protein kinase (PKA) using an analog-sensitive catalytic subunit.

Schauble S, King CC, Darshi M, Koller A, Shah K, Taylor SS.

J Biol Chem. 2007 May 18;282(20):14952-9. Epub 2007 Jan 22.

16.

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