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Items: 12

1.

AZD5153: A Novel Bivalent BET Bromodomain Inhibitor Highly Active against Hematologic Malignancies.

Rhyasen GW, Hattersley MM, Yao Y, Dulak A, Wang W, Petteruti P, Dale IL, Boiko S, Cheung T, Zhang J, Wen S, Castriotta L, Lawson D, Collins M, Bao L, Ahdesmaki MJ, Walker G, O'Connor G, Yeh TC, Rabow AA, Dry JR, Reimer C, Lyne P, Mills GB, Fawell SE, Waring MJ, Zinda M, Clark E, Chen H.

Mol Cancer Ther. 2016 Nov;15(11):2563-2574. Epub 2016 Aug 29.

2.

Structure-Activity Relationships of the Sustained Effects of Adenosine A2A Receptor Agonists Driven by Slow Dissociation Kinetics.

Hothersall JD, Guo D, Sarda S, Sheppard RJ, Chen H, Keur W, Waring MJ, IJzerman AP, Hill SJ, Dale IL, Rawlins PB.

Mol Pharmacol. 2017 Jan;91(1):25-38. Epub 2016 Nov 1.

3.

Assessment of cardiomyocyte contraction in human-induced pluripotent stem cell-derived cardiomyocytes.

Pointon A, Harmer AR, Dale IL, Abi-Gerges N, Bowes J, Pollard C, Garside H.

Toxicol Sci. 2015 Apr;144(2):227-37. doi: 10.1093/toxsci/kfu312. Epub 2014 Dec 22.

PMID:
25538221
4.

Measurement of [Ca2+] using the Fluorometric Imaging Plate Reader (FLIPR).

Sullivan E, Tucker EM, Dale IL.

Methods Mol Biol. 1999;114:125-33. Review. No abstract available.

PMID:
10081013
5.

Regulation of c-fos transcription by chemopreventive isoflavonoids and lignans in MDA-MB-468 breast cancer cells.

Schultze-Mosgau MH, Dale IL, Gant TW, Chipman JK, Kerr DJ, Gescher A.

Eur J Cancer. 1998 Aug;34(9):1425-31.

PMID:
9849427
6.

Reversal of P-glycoprotein-mediated multidrug resistance by XR9051, a novel diketopiperazine derivative.

Dale IL, Tuffley W, Callaghan R, Holmes JA, Martin K, Luscombe M, Mistry P, Ryder H, Stewart AJ, Charlton P, Twentyman PR, Bevan P.

Br J Cancer. 1998 Oct;78(7):885-92.

7.

Synthesis and biological evaluation of a series of flavones designed as inhibitors of protein tyrosine kinases.

Cunningham BD, Threadgill MD, Groundwater PW, Dale IL, Hickman JA.

Anticancer Drug Des. 1992 Oct;7(5):365-84.

PMID:
1388629
8.

Protein kinase C--a novel target for rational anti-cancer drug design?

Gescher A, Dale IL.

Anticancer Drug Des. 1989 Aug;4(2):93-105. Review. No abstract available.

PMID:
2679620
11.
12.

Effect of two inducers of cellular differentiation on the glutathione status of human HL-60 promyelocytic leukaemia and A549 lung carcinoma cells.

Lazenby CM, Gescher A, Dale IL.

Biochem Pharmacol. 1987 Sep 1;36(17):2869-71. No abstract available.

PMID:
3477230

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