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Items: 6

1.

Identification and Mitigation of Reactive Metabolites of 2-Aminoimidazole-Containing Microsomal Prostaglandin E Synthase-1 Inhibitors Terminated Due to Clinical Drug-Induced Liver Injury.

Norman BH, Fisher MJ, Schiffler MA, Kuklish SL, Hughes NE, Czeskis BA, Cassidy KC, Abraham TL, Alberts JJ, Luffer-Atlas D.

J Med Chem. 2018 Mar 8;61(5):2041-2051. doi: 10.1021/acs.jmedchem.7b01806. Epub 2018 Feb 15.

PMID:
29425457
2.

Comparison between Radioanalysis and 19F Nuclear Magnetic Resonance Spectroscopy in the Determination of Mass Balance, Metabolism, and Distribution of Pefloxacin.

Hu H, Katyayan KK, Czeskis BA, Perkins EJ, Kulanthaivel P.

Drug Metab Dispos. 2017 Apr;45(4):399-408. doi: 10.1124/dmd.116.073809. Epub 2017 Feb 10.

3.

Synthesis of C-14 radiolabeled glucagon receptor antagonist and its use in a human mass balance study.

Czeskis BA, Satonin DK.

J Labelled Comp Radiopharm. 2017 Feb;60(2):110-115. doi: 10.1002/jlcr.3477. Epub 2016 Dec 1.

PMID:
27910129
4.

Metabolism and disposition of a beta 3-adrenergic receptor agonist LY 368842 in male Fisher 344 rats.

Abraham TL, Lindsay TJ, Chay SH, Czeskis BA, He MM.

Xenobiotica. 2005 Jun;35(6):647-60.

PMID:
16192113
5.

Identification, synthesis and pharmacological activity of moxonidine metabolites.

Wirth DD, He MM, Czeskis BA, Zimmerman KM, Roettig U, Stenzel W, Steinberg MI.

Eur J Med Chem. 2002 Jan;37(1):23-34.

PMID:
11841872
6.

Metabolism and disposition of moxonidine in Fischer 344 rats.

He MM, Abraham TL, Lindsay TJ, Chay SH, Czeskis BA, Shipley LA.

Drug Metab Dispos. 2000 Apr;28(4):446-59.

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