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Items: 35

1.

Combinatorial synthesis of deuterium-enriched (S)-oxybutynin.

Li F, Jiang W, Czarnik AW, Li W.

Mol Divers. 2016 Aug;20(3):605-10. doi: 10.1007/s11030-016-9660-4. Epub 2016 Feb 6.

PMID:
26852022
2.

Combinatorial synthesis of deuterium-enriched atorvastatin.

Li F, Jiang W, Czarnik AW, Li W.

Mol Divers. 2016 May;20(2):453-9. doi: 10.1007/s11030-015-9655-6. Epub 2016 Jan 25.

PMID:
26809618
3.

Differentiation of antiinflammatory and antitumorigenic properties of stabilized enantiomers of thalidomide analogs.

Jacques V, Czarnik AW, Judge TM, Van der Ploeg LH, DeWitt SH.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):E1471-9. doi: 10.1073/pnas.1417832112. Epub 2015 Mar 9. Erratum in: Proc Natl Acad Sci U S A. 2015 May 12;112(19):E2553.

4.

This issue introduces a set of ideas called "Distributed Drug Discovery (D(3))".

Czarnik AW.

J Comb Chem. 2009 Jan-Feb;11(1):1-2. doi: 10.1021/cc800203n. No abstract available.

PMID:
19133837
5.

Editorial.

Czarnik AW.

J Comb Chem. 2008 Mar;10(2):149. doi: 10.1021/cc800014f. No abstract available.

PMID:
27517743
6.

Editorial.

Czarnik AW.

J Comb Chem. 2008 Jan;10(1):1-2. doi: 10.1021/cc7001759. No abstract available.

PMID:
27517636
7.

Editorial.

Czarnik AW.

J Comb Chem. 2003 May;5(3):197. doi: 10.1021/cc0300309. No abstract available.

PMID:
27518193
8.

Solid-phase synthesis of alkyl aryl ethers via the Ullmann condensation.

Xiao XY, Li R, Hurst D, Zhuang H, Shi S, Czarnik AW, Robichaud AJ, Wacker DA, Robertson DW.

J Comb Chem. 2002 Sep-Oct;4(5):536-9.

PMID:
12217028
9.

Editorial.

Czarnik AW.

J Comb Chem. 2000 Nov;2(6):561. doi: 10.1021/cc0000848. No abstract available.

PMID:
27517881
10.

Kinetic study of organic reactions on polystyrene grafted MicroTubes

Li W, Czarnik AW, Xiao XY, Lillig J.

J Comb Chem. 2000 May;2(3):224-7. No abstract available.

PMID:
10827926
11.

RNA as a small-molecule drug target - Letter to the Editor.

Czarnik AW.

Drug Discov Today. 2000 Mar;5(3):94. No abstract available.

PMID:
10675880
12.

Solid-phase synthesis supports are like solvents

Czarnik AW.

Biotechnol Bioeng. 1998 Winter;61(1):77-9. No abstract available.

PMID:
10099499
13.

A combinatorial synthesis of tyrphostins via the "directed sorting" method.

Shi S, Xiao XY, Czarnik AW.

Biotechnol Bioeng. 1998 Winter;61(1):7-12.

PMID:
10099490
14.

Editorial.

Czarnik AW.

J Comb Chem. 1999 Jan 12;1(1):1-2. doi: 10.1021/cc980033z. No abstract available.

PMID:
27383634
15.

Combinatorial chemistry.

Czarnik AW, Keene JD.

Curr Biol. 1998 Oct 8;8(20):R705-7. No abstract available.

16.

Inhibitors of protein-RNA complexation that target the RNA: specific recognition of human immunodeficiency virus type 1 TAR RNA by small organic molecules.

Mei HY, Cui M, Heldsinger A, Lemrow SM, Loo JA, Sannes-Lowery KA, Sharmeen L, Czarnik AW.

Biochemistry. 1998 Oct 6;37(40):14204-12.

PMID:
9760258
17.

Binding of neomycin to the TAR element of HIV-1 RNA induces dissociation of Tat protein by an allosteric mechanism.

Wang S, Huber PW, Cui M, Czarnik AW, Mei HY.

Biochemistry. 1998 Apr 21;37(16):5549-57.

PMID:
9548939
18.

Encoding strategies in combinatorial chemistry.

Czarnik AW.

Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):12738-9. Review. No abstract available.

19.

Combinatorial chemistry

Czarnik AW.

Curr Opin Chem Biol. 1997 Jun;1(1):1-2. No abstract available.

PMID:
9667846
20.

Encoding methods for combinatorial chemistry.

Czarnik AW.

Curr Opin Chem Biol. 1997 Jun;1(1):60-6. Review.

PMID:
9667828
21.

Discovery of selective, small-molecule inhibitors of RNA complexes--II. Self-splicing group I intron ribozyme.

Mei HY, Cui M, Lemrow SM, Czarnik AW.

Bioorg Med Chem. 1997 Jun;5(6):1185-95.

PMID:
9222512
22.

Discovery of selective, small-molecule inhibitors of RNA complexes--I. The Tat protein/TAR RNA complexes required for HIV-1 transcription.

Mei HY, Mack DP, Galan AA, Halim NS, Heldsinger A, Loo JA, Moreland DW, Sannes-Lowery KA, Sharmeen L, Truong HN, Czarnik AW.

Bioorg Med Chem. 1997 Jun;5(6):1173-84.

PMID:
9222511
23.

Inhibition of self-splicing group I intron RNA: high-throughput screening assays.

Mei HY, Cui M, Sutton ST, Truong HN, Chung FZ, Czarnik AW.

Nucleic Acids Res. 1996 Dec 15;24(24):5051-3.

24.

Chelation-enhanced fluorescence chemosensing of Pb(II), an inherently quenching metal ion.

Chae MY, Yoon J, Czarnik AW.

J Mol Recognit. 1996 Jul-Aug;9(4):297-303.

PMID:
9131471
25.

The impact of polystyrene resins in solid-phase organic synthesis.

MacDonald AA, Dewitt SH, Ghosh S, Hogan EM, Kieras L, Czarnik AW, Ramage R.

Mol Divers. 1996 May;1(3):183-6.

PMID:
9237209
26.

Automated synthesis and combinatorial chemistry.

DeWitt SH, Czarnik AW.

Curr Opin Biotechnol. 1995 Dec 1;6(6):640-5.

PMID:
8791299
27.

Desperately seeking sensors.

Czarnik AW.

Chem Biol. 1995 Jul;2(7):423-8. Review. Erratum in: Chem Biol 1995 Sep;2(9):631.

28.

Synthesis and transacylating reactivity of beta-cyclodextrin ethylenediamines.

Beeson JC, Czarnik AW.

Bioorg Med Chem. 1994 Apr;2(4):297-303.

PMID:
7922140
29.

Intramolecular carboxylate catalysis in the depurination of a 7-methylguanosine derivative.

Van Arman SA, Czarnik AW.

Bioorg Med Chem. 1993 Nov;1(5):369-74.

PMID:
8081867
30.

Fluorescent chemosensing of catechol and catecholamines in water.

Yoon J, Czarnik AW.

Bioorg Med Chem. 1993 Oct;1(4):267-71.

PMID:
8081857
31.

Structural requirements for efficient photoinduced electron transfer (PET) quenching in 9-aminoalkylanthracenes.

Beeson JC, Huston ME, Pollard DA, Venkatachalam TK, Czarnik AW.

J Fluoresc. 1993 Jun;3(2):65-8. doi: 10.1007/BF00865319.

PMID:
24234769
32.

Fluorimetric metal ion sensing usingN-methyl-9-anthrylhydroxamic acid.

Chae MY, Czarnik AW.

J Fluoresc. 1992 Dec;2(4):225-9. doi: 10.1007/BF00865280.

PMID:
24241716
33.

Synthesis, stereochemistry, intramolecular cyclization, and rates of hydrolysis of adenosine 2',3'-acetals.

Bakthavachalam V, Lin LG, Cherian XM, Czarnik AW.

Carbohydr Res. 1987 Dec 1;170(1):124-35. No abstract available.

PMID:
3435902
34.

An assay to determine the kinetics of RNA cleavage.

Corcoran R, Labelle M, Czarnik AW, Breslow R.

Anal Biochem. 1985 Feb 1;144(2):563-8.

PMID:
2581471
35.

Hexadeoxycycloheptaamylose-pyridoxamine, an artificial transaminase with a "deeper" binding pocket.

Czarnik AW, Breslow R.

Carbohydr Res. 1984 May 15;128(1):133-9.

PMID:
6733723

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