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Items: 1 to 50 of 164

1.

Development of a stress response therapy targeting aggressive prostate cancer.

Nguyen HG, Conn CS, Kye Y, Xue L, Forester CM, Cowan JE, Hsieh AC, Cunningham JT, Truillet C, Tameire F, Evans MJ, Evans CP, Yang JC, Hann B, Koumenis C, Walter P, Carroll PR, Ruggero D.

Sci Transl Med. 2018 May 2;10(439). pii: eaar2036. doi: 10.1126/scitranslmed.aar2036.

PMID:
29720449
2.

Transcription factor ΔFosB acts within the nucleus of the solitary tract to increase mean arterial pressure during exposures to intermittent hypoxia.

Wu Q, Cunningham JT, Mifflin S.

Am J Physiol Heart Circ Physiol. 2018 Feb 1;314(2):H270-H277. doi: 10.1152/ajpheart.00268.2017. Epub 2017 Nov 3.

PMID:
29101166
3.

Angiotensin converting enzyme 1 in the median preoptic nucleus contributes to chronic intermittent hypoxia hypertension.

Faulk KE, Nedungadi TP, Cunningham JT.

Physiol Rep. 2017 May;5(10). pii: e13277. doi: 10.14814/phy2.13277.

4.

Chronic intermittent hypoxia induces oxidative stress and inflammation in brain regions associated with early-stage neurodegeneration.

Snyder B, Shell B, Cunningham JT, Cunningham RL.

Physiol Rep. 2017 May;5(9). pii: e13258. doi: 10.14814/phy2.13258.

5.

Noninvasive Measurement of mTORC1 Signaling with 89Zr-Transferrin.

Truillet C, Cunningham JT, Parker MFL, Huynh LT, Conn CS, Ruggero D, Lewis JS, Evans MJ.

Clin Cancer Res. 2017 Jun 15;23(12):3045-3052. doi: 10.1158/1078-0432.CCR-16-2448. Epub 2016 Dec 22.

PMID:
28007777
6.

Role of angiotensin-converting enzyme 1 within the median preoptic nucleus following chronic intermittent hypoxia.

Faulk K, Shell B, Nedungadi TP, Cunningham JT.

Am J Physiol Regul Integr Comp Physiol. 2017 Feb 1;312(2):R245-R252. doi: 10.1152/ajpregu.00472.2016. Epub 2016 Dec 21.

7.

Disentangling opposing effects of motivational states on pain perception.

Geuter S, Cunningham JT, Wager TD.

Pain Rep. 2016 Sep;1(3). pii: e574. No abstract available.

8.

Neural Control of Blood Pressure in Chronic Intermittent Hypoxia.

Shell B, Faulk K, Cunningham JT.

Curr Hypertens Rep. 2016 Mar;18(3):19. doi: 10.1007/s11906-016-0627-8. Review.

9.

Impaired sodium-evoked paraventricular nucleus neuronal activation and blood pressure regulation in conscious Sprague-Dawley rats lacking central Gαi2 proteins.

Carmichael CY, Carmichael AC, Kuwabara JT, Cunningham JT, Wainford RD.

Acta Physiol (Oxf). 2016 Mar;216(3):314-29. doi: 10.1111/apha.12610. Epub 2015 Oct 19.

10.

Neurogenic mechanisms underlying the rapid onset of sympathetic responses to intermittent hypoxia.

Mifflin S, Cunningham JT, Toney GM.

J Appl Physiol (1985). 2015 Dec 15;119(12):1441-8. doi: 10.1152/japplphysiol.00198.2015. Epub 2015 May 21. Review.

11.

High salt intake increases blood pressure via BDNF-mediated downregulation of KCC2 and impaired baroreflex inhibition of vasopressin neurons.

Choe KY, Han SY, Gaub P, Shell B, Voisin DL, Knapp BA, Barker PA, Brown CH, Cunningham JT, Bourque CW.

Neuron. 2015 Feb 4;85(3):549-60. doi: 10.1016/j.neuron.2014.12.048. Epub 2015 Jan 22.

12.

Angiotensin II type 1a receptors in subfornical organ contribute towards chronic intermittent hypoxia-associated sustained increase in mean arterial pressure.

Saxena A, Little JT, Nedungadi TP, Cunningham JT.

Am J Physiol Heart Circ Physiol. 2015 Mar 1;308(5):H435-46. doi: 10.1152/ajpheart.00747.2014. Epub 2014 Dec 24.

13.

Angiotensin II induces membrane trafficking of natively expressed transient receptor potential vanilloid type 4 channels in hypothalamic 4B cells.

Saxena A, Bachelor M, Park YH, Carreno FR, Nedungadi TP, Cunningham JT.

Am J Physiol Regul Integr Comp Physiol. 2014 Oct 15;307(8):R945-55. doi: 10.1152/ajpregu.00224.2014. Epub 2014 Jul 30.

14.

ANG II receptor subtype 1a gene knockdown in the subfornical organ prevents increased drinking behavior in bile duct-ligated rats.

Walch JD, Nedungadi TP, Cunningham JT.

Am J Physiol Regul Integr Comp Physiol. 2014 Sep 15;307(6):R597-607. doi: 10.1152/ajpregu.00163.2014. Epub 2014 Jul 9.

15.

Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer.

Cunningham JT, Moreno MV, Lodi A, Ronen SM, Ruggero D.

Cell. 2014 May 22;157(5):1088-103. doi: 10.1016/j.cell.2014.03.052. Erratum in: Cell. 2014 Jul 31;158(3):689.

16.

Decreased genetic dosage of hepatic Yin Yang 1 causes diabetic-like symptoms.

Verdeguer F, Blättler SM, Cunningham JT, Hall JA, Chim H, Puigserver P.

Mol Endocrinol. 2014 Mar;28(3):308-16. doi: 10.1210/me.2013-1173. Epub 2014 Jan 27.

17.

Differential regulation of TRPC4 in the vasopressin magnocellular system by water deprivation and hepatic cirrhosis in the rat.

Nedungadi TP, Cunningham JT.

Am J Physiol Regul Integr Comp Physiol. 2014 Mar 1;306(5):R304-14. doi: 10.1152/ajpregu.00388.2013. Epub 2013 Dec 18.

18.

New connections between old pathways: PDK1 signaling promotes cellular transformation through PLK1-dependent MYC stabilization.

Cunningham JT, Ruggero D.

Cancer Discov. 2013 Oct;3(10):1099-102. doi: 10.1158/2159-8290.CD-13-0581.

19.

Chronic intermittent hypoxia increases sympathetic control of blood pressure: role of neuronal activity in the hypothalamic paraventricular nucleus.

Sharpe AL, Calderon AS, Andrade MA, Cunningham JT, Mifflin SW, Toney GM.

Am J Physiol Heart Circ Physiol. 2013 Dec;305(12):H1772-80. doi: 10.1152/ajpheart.00592.2013. Epub 2013 Oct 4.

20.

Knockdown of tyrosine hydroxylase in the nucleus of the solitary tract reduces elevated blood pressure during chronic intermittent hypoxia.

Bathina CS, Rajulapati A, Franzke M, Yamamoto K, Cunningham JT, Mifflin S.

Am J Physiol Regul Integr Comp Physiol. 2013 Nov 1;305(9):R1031-9. doi: 10.1152/ajpregu.00260.2013. Epub 2013 Sep 18.

21.

Central losartan attenuates increases in arterial pressure and expression of FosB/ΔFosB along the autonomic axis associated with chronic intermittent hypoxia.

Knight WD, Saxena A, Shell B, Nedungadi TP, Mifflin SW, Cunningham JT.

Am J Physiol Regul Integr Comp Physiol. 2013 Nov 1;305(9):R1051-8. doi: 10.1152/ajpregu.00541.2012. Epub 2013 Sep 11.

22.

Investigating Myc-dependent translational regulation in normal and cancer cells.

Cunningham JT, Pourdehnad M, Stumpf CR, Ruggero D.

Methods Mol Biol. 2013;1012:201-12. doi: 10.1007/978-1-62703-429-6_13.

23.

Editorial Focus: the brain renin-angiotensin system and hypertension. Focus on: hypertension in mice with transgenic activation of the brain renin-angiotensin system is vasopressin dependent.

Cunningham JT.

Am J Physiol Regul Integr Comp Physiol. 2013 Aug 1;305(3):R173-4. doi: 10.1152/ajpregu.00272.2013. Epub 2013 Jun 5. No abstract available.

24.

Nuclear factor κB mediates suppression of canonical transient receptor potential 6 expression by reactive oxygen species and protein kinase C in kidney cells.

Wang Y, Ding M, Chaudhari S, Ding Y, Yuan J, Stankowska D, He S, Krishnamoorthy R, Cunningham JT, Ma R.

J Biol Chem. 2013 May 3;288(18):12852-65. doi: 10.1074/jbc.M112.410357. Epub 2013 Mar 22.

25.

Intracerebroventricular losartan infusion modulates angiotensin II type 1 receptor expression in the subfornical organ and drinking behaviour in bile-duct-ligated rats.

Walch JD, Carreño FR, Cunningham JT.

Exp Physiol. 2013 Apr;98(4):922-33. doi: 10.1113/expphysiol.2012.068593. Epub 2012 Dec 13.

26.

ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth.

Hart LS, Cunningham JT, Datta T, Dey S, Tameire F, Lehman SL, Qiu B, Zhang H, Cerniglia G, Bi M, Li Y, Gao Y, Liu H, Li C, Maity A, Thomas-Tikhonenko A, Perl AE, Koong A, Fuchs SY, Diehl JA, Mills IG, Ruggero D, Koumenis C.

J Clin Invest. 2012 Dec;122(12):4621-34. doi: 10.1172/JCI62973. Epub 2012 Nov 12.

27.

Selective up-regulation of JunD transcript and protein expression in vasopressinergic supraoptic nucleus neurones in water-deprived rats.

Yao ST, Gouraud SS, Qiu J, Cunningham JT, Paton JF, Murphy D.

J Neuroendocrinol. 2012 Dec;24(12):1542-52. doi: 10.1111/j.1365-2826.2012.02362.x.

28.

Expression and distribution of TRPV2 in rat brain.

Nedungadi TP, Dutta M, Bathina CS, Caterina MJ, Cunningham JT.

Exp Neurol. 2012 Sep;237(1):223-37. doi: 10.1016/j.expneurol.2012.06.017. Epub 2012 Jun 27.

29.

Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle.

Blättler SM, Verdeguer F, Liesa M, Cunningham JT, Vogel RO, Chim H, Liu H, Romanino K, Shirihai OS, Vazquez F, Rüegg MA, Shi Y, Puigserver P.

Mol Cell Biol. 2012 Aug;32(16):3333-46. doi: 10.1128/MCB.00337-12. Epub 2012 Jun 18.

30.

An Essential role for DeltaFosB in the median preoptic nucleus in the sustained hypertensive effects of chronic intermittent hypoxia.

Cunningham JT, Knight WD, Mifflin SW, Nestler EJ.

Hypertension. 2012 Jul;60(1):179-87. doi: 10.1161/HYPERTENSIONAHA.112.193789. Epub 2012 Jun 11.

31.

ΔFosB in the supraoptic nucleus contributes to hyponatremia in rats with cirrhosis.

Cunningham JT, Nedungadi TP, Walch JD, Nestler EJ, Gottlieb HB.

Am J Physiol Regul Integr Comp Physiol. 2012 Jul 15;303(2):R177-85. doi: 10.1152/ajpregu.00142.2012. Epub 2012 May 23.

32.

Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling.

Blättler SM, Cunningham JT, Verdeguer F, Chim H, Haas W, Liu H, Romanino K, Rüegg MA, Gygi SP, Shi Y, Puigserver P.

Cell Metab. 2012 Apr 4;15(4):505-17. doi: 10.1016/j.cmet.2012.03.008.

33.

Region-specific changes in transient receptor potential vanilloid channel expression in the vasopressin magnocellular system in hepatic cirrhosis-induced hyponatraemia.

Nedungadi TP, Carreño FR, Walch JD, Bathina CS, Cunningham JT.

J Neuroendocrinol. 2012 Apr;24(4):642-52. doi: 10.1111/j.1365-2826.2011.02273.x.

34.

Endoscopic ultrasound with biopsy of omental mass for cholangiocarcinoma diagnosis in cirrhosis.

Rial NS, Gilchrist KB, Henderson JT, Bhattacharyya AK, Boyer TD, Nadir A, Cunningham JT.

World J Gastrointest Endosc. 2011 Jun 16;3(6):124-8. doi: 10.4253/wjge.v3.i6.124.

35.

Brain-derived neurotrophic factor-tyrosine kinase B pathway mediates NMDA receptor NR2B subunit phosphorylation in the supraoptic nuclei following progressive dehydration.

Carreño FR, Walch JD, Dutta M, Nedungadi TP, Cunningham JT.

J Neuroendocrinol. 2011 Oct;23(10):894-905. doi: 10.1111/j.1365-2826.2011.02209.x.

36.

Role of superior laryngeal nerve and Fos staining following dehydration and rehydration in the rat.

Gottlieb HB, Ji LL, Cunningham JT.

Physiol Behav. 2011 Oct 24;104(5):1053-8. doi: 10.1016/j.physbeh.2011.07.008. Epub 2011 Jul 14.

37.

Chronic intermittent hypoxia increases blood pressure and expression of FosB/DeltaFosB in central autonomic regions.

Knight WD, Little JT, Carreno FR, Toney GM, Mifflin SW, Cunningham JT.

Am J Physiol Regul Integr Comp Physiol. 2011 Jul;301(1):R131-9. doi: 10.1152/ajpregu.00830.2010. Epub 2011 May 4.

38.

Use of endoscopic ultrasound for diagnosis of cholangiocarcinoma in auto-immune hepatitis.

Rial NS, Henderson JT, Bhattacharyya AK, Nadir A, Cunningham JT.

World J Gastrointest Endosc. 2010 Dec 16;2(12):404-7. doi: 10.4253/wjge.v2.i12.404.

39.

Dehydration followed by sham rehydration contributes to reduced neuronal activation in vasopressinergic supraoptic neurons after water deprivation.

Knight WD, Ji LL, Little JT, Cunningham JT.

Am J Physiol Regul Integr Comp Physiol. 2010 Nov;299(5):R1232-40. doi: 10.1152/ajpregu.00066.2010. Epub 2010 Sep 15.

40.

The evolution of man.

Cunningham JT.

Sci Prog. 2009;92(Pt 3-4):317-26. Review. No abstract available.

PMID:
19960873
41.

Chronic sustained hypoxia enhances both evoked EPSCs and norepinephrine inhibition of glutamatergic afferent inputs in the nucleus of the solitary tract.

Zhang W, Carreño FR, Cunningham JT, Mifflin SW.

J Neurosci. 2009 Mar 11;29(10):3093-102. doi: 10.1523/JNEUROSCI.2648-08.2009.

42.

Altered central TRPV4 expression and lipid raft association related to inappropriate vasopressin secretion in cirrhotic rats.

Carreño FR, Ji LL, Cunningham JT.

Am J Physiol Regul Integr Comp Physiol. 2009 Feb;296(2):R454-66. doi: 10.1152/ajpregu.90460.2008. Epub 2008 Dec 17.

43.

Chronic sustained and intermittent hypoxia reduce function of ATP-sensitive potassium channels in nucleus of the solitary tract.

Zhang W, Carreño FR, Cunningham JT, Mifflin SW.

Am J Physiol Regul Integr Comp Physiol. 2008 Nov;295(5):R1555-62. doi: 10.1152/ajpregu.90390.2008. Epub 2008 Sep 10.

44.

Intra-carotid hyperosmotic stimulation increases Fos staining in forebrain organum vasculosum laminae terminalis neurones that project to the hypothalamic paraventricular nucleus.

Shi P, Martinez MA, Calderon AS, Chen Q, Cunningham JT, Toney GM.

J Physiol. 2008 Nov 1;586(21):5231-45. doi: 10.1113/jphysiol.2008.159665. Epub 2008 Aug 28.

45.

Chronic intermittent hypoxia sensitizes acute hypothalamic-pituitary-adrenal stress reactivity and Fos induction in the rat locus coeruleus in response to subsequent immobilization stress.

Ma S, Mifflin SW, Cunningham JT, Morilak DA.

Neuroscience. 2008 Jul 17;154(4):1639-47. doi: 10.1016/j.neuroscience.2008.04.068. Epub 2008 May 6.

46.

Large-diameter biliary orifice balloon dilation to aid in endoscopic bile duct stone removal: a multicenter series.

Attasaranya S, Cheon YK, Vittal H, Howell DA, Wakelin DE, Cunningham JT, Ajmere N, Ste Marie RW Jr, Bhattacharya K, Gupta K, Freeman ML, Sherman S, McHenry L, Watkins JL, Fogel EL, Schmidt S, Lehman GA.

Gastrointest Endosc. 2008 Jun;67(7):1046-52. doi: 10.1016/j.gie.2007.08.047. Epub 2008 Feb 21.

PMID:
18178208
47.

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.

Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, Mootha VK, Puigserver P.

Nature. 2007 Nov 29;450(7170):736-40.

PMID:
18046414
48.

Antegrade bowel intussusception after remote Whipple and Puestow procedures for treatment of pancreas divisum.

Gigena M, Villar HV, Knowles NG, Cunningham JT, Outwater EK, Leon LR Jr.

World J Gastroenterol. 2007 Nov 28;13(44):5954-6.

49.

Induction of c-Fos and DeltaFosB immunoreactivity in rat brain by Vagal nerve stimulation.

Cunningham JT, Mifflin SW, Gould GG, Frazer A.

Neuropsychopharmacology. 2008 Jul;33(8):1884-95. Epub 2007 Oct 24.

50.

Loss of the eukaryotic initiation factor 3f in pancreatic cancer.

Doldan A, Chandramouli A, Shanas R, Bhattacharyya A, Cunningham JT, Nelson MA, Shi J.

Mol Carcinog. 2008 Mar;47(3):235-44.

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