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Endophilin A2 promotes HER2 internalization and sensitivity to trastuzumab-based therapy in HER2-positive breast cancers.

Baldassarre T, Truesdell P, Craig AW.

Breast Cancer Res. 2017 Oct 3;19(1):110. doi: 10.1186/s13058-017-0900-z.


A novel immunotherapy targeting MMP-14 limits hypoxia, immune suppression and metastasis in triple-negative breast cancer models.

Ling B, Watt K, Banerjee S, Newsted D, Truesdell P, Adams J, Sidhu SS, Craig AWB.

Oncotarget. 2017 May 9;8(35):58372-58385. doi: 10.18632/oncotarget.17702. eCollection 2017 Aug 29.


CXCL10 alters the tumour immune microenvironment and disease progression in a syngeneic murine model of high-grade serous ovarian cancer.

K Au K, Peterson N, Truesdell P, Reid-Schachter G, Khalaj K, Ren R, Francis JA, Graham CH, Craig AW, Koti M.

Gynecol Oncol. 2017 Jun;145(3):436-445. doi: 10.1016/j.ygyno.2017.03.007. Epub 2017 Mar 17.


STAT1-associated intratumoural TH1 immunity predicts chemotherapy resistance in high-grade serous ovarian cancer.

Au KK, Le Page C, Ren R, Meunier L, Clément I, Tyrishkin K, Peterson N, Kendall-Dupont J, Childs T, Francis JA, Graham CH, Craig AW, Squire JA, Mes-Masson AM, Koti M.

J Pathol Clin Res. 2016 Sep 19;2(4):259-270. eCollection 2016 Oct.


Dataset of STAT5A status in breast cancer.

Mukhopadhyay UK, Cass J, Raptis L, Craig AW, Bourdeau V, Varma S, Gupta SS, Elliott BE, Ferbeyre G.

Data Brief. 2016 Mar 4;7:490-2. doi: 10.1016/j.dib.2016.02.073. eCollection 2016 Jun.


STAT5A is regulated by DNA damage via the tumor suppressor p53.

Mukhopadhyay UK, Cass J, Raptis L, Craig AW, Bourdeau V, Varma S, SenGupta S, Elliott BE, Ferbeyre G.

Cytokine. 2016 Jun;82:70-9. doi: 10.1016/j.cyto.2016.01.013. Epub 2016 Feb 11.


Activation of the PD-1/PD-L1 immune checkpoint confers tumor cell chemoresistance associated with increased metastasis.

Black M, Barsoum IB, Truesdell P, Cotechini T, Macdonald-Goodfellow SK, Petroff M, Siemens DR, Koti M, Craig AW, Graham CH.

Oncotarget. 2016 Mar 1;7(9):10557-67. doi: 10.18632/oncotarget.7235.


Demonstration of elevated levels of active cathepsin S in dextran sulfate sodium colitis using a new activatable probe.

Barlow N, Nasser Y, Zhao P, Sharma N, Guerrero-Alba R, Edgington-Mitchell LE, Lieu T, Veldhuis NA, Poole DP, Conner JW, Lindström E, Craig AW, Graham B, Vanner SJ, Bunnett NW.

Neurogastroenterol Motil. 2015 Nov;27(11):1675-80. doi: 10.1111/nmo.12656. Epub 2015 Aug 24.


CIP4 promotes metastasis in triple-negative breast cancer and is associated with poor patient prognosis.

Cerqueira OL, Truesdell P, Baldassarre T, Vilella-Arias SA, Watt K, Meens J, Chander H, Osório CA, Soares FA, Reis EM, Craig AW.

Oncotarget. 2015 Apr 20;6(11):9397-408.


Endophilin A2 Promotes TNBC Cell Invasion and Tumor Metastasis.

Baldassarre T, Watt K, Truesdell P, Meens J, Schneider MM, Sengupta SK, Craig AW.

Mol Cancer Res. 2015 Jun;13(6):1044-55. doi: 10.1158/1541-7786.MCR-14-0573. Epub 2015 Mar 17.


Editorial: leukocyte-targeting toxins as therapeutics in allergic asthma.

Sharma N, Craig AW.

J Leukoc Biol. 2015 Mar;97(3):435-6. doi: 10.1189/jlb.3CE1014-462R. No abstract available.


Toca-1 is suppressed by p53 to limit breast cancer cell invasion and tumor metastasis.

Chander H, Brien CD, Truesdell P, Watt K, Meens J, Schick C, Germain D, Craig AW.

Breast Cancer Res. 2014 Dec 30;16(6):3413. doi: 10.1186/s13058-014-0503-x.


CIP4 promotes lung adenocarcinoma metastasis and is associated with poor prognosis.

Truesdell P, Ahn J, Chander H, Meens J, Watt K, Yang X, Craig AW.

Oncogene. 2015 Jul;34(27):3527-35. doi: 10.1038/onc.2014.280. Epub 2014 Sep 1.


Oncogenic KIT-induced aggressive systemic mastocytosis requires SHP2/PTPN11 phosphatase for disease progression in mice.

Sharma N, Everingham S, Zeng LF, Zhang ZY, Kapur R, Craig AW.

Oncotarget. 2014 Aug 15;5(15):6130-41.


SHP2 phosphatase promotes mast cell chemotaxis toward stem cell factor via enhancing activation of the Lyn/Vav/Rac signaling axis.

Sharma N, Everingham S, Ramdas B, Kapur R, Craig AW.

J Immunol. 2014 May 15;192(10):4859-66. doi: 10.4049/jimmunol.1301155. Epub 2014 Apr 14.


Calpains promote neutrophil recruitment and bacterial clearance in an acute bacterial peritonitis model.

Kumar V, Everingham S, Hall C, Greer PA, Craig AW.

Eur J Immunol. 2014 Mar;44(3):831-41. doi: 10.1002/eji.201343757. Epub 2013 Dec 27.


Fer protein-tyrosine kinase promotes lung adenocarcinoma cell invasion and tumor metastasis.

Ahn J, Truesdell P, Meens J, Kadish C, Yang X, Boag AH, Craig AW.

Mol Cancer Res. 2013 Aug;11(8):952-63. doi: 10.1158/1541-7786.MCR-13-0003-T. Epub 2013 May 22.


Fer kinase limits neutrophil chemotaxis toward end target chemoattractants.

Khajah M, Andonegui G, Chan R, Craig AW, Greer PA, McCafferty DM.

J Immunol. 2013 Mar 1;190(5):2208-16. doi: 10.4049/jimmunol.1200322. Epub 2013 Jan 25.


Transducer of Cdc42-dependent actin assembly promotes breast cancer invasion and metastasis.

Chander H, Truesdell P, Meens J, Craig AW.

Oncogene. 2013 Jun 20;32(25):3080-90. doi: 10.1038/onc.2012.317. Epub 2012 Jul 23.


Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT.

Mali RS, Ma P, Zeng LF, Martin H, Ramdas B, He Y, Sims E, Nabinger S, Ghosh J, Sharma N, Munugalavadla V, Chatterjee A, Li S, Sandusky G, Craig AW, Bunting KD, Feng GS, Chan RJ, Zhang ZY, Kapur R.

Blood. 2012 Sep 27;120(13):2669-78. Epub 2012 Jul 17.


The family infighting continues: dualling SRC family kinases now linked to activating IgG receptor signaling and anaphylaxis.

Craig AW.

Front Immunol. 2012 Jun 6;3:137. doi: 10.3389/fimmu.2012.00137. eCollection 2012. No abstract available.


FES kinase promotes mast cell recruitment to mammary tumors via the stem cell factor/KIT receptor signaling axis.

Kwok E, Everingham S, Zhang S, Greer PA, Allingham JS, Craig AW.

Mol Cancer Res. 2012 Jul;10(7):881-91. doi: 10.1158/1541-7786.MCR-12-0115. Epub 2012 May 15.


SH2 domain-containing phosphatase 2 is a critical regulator of connective tissue mast cell survival and homeostasis in mice.

Sharma N, Kumar V, Everingham S, Mali RS, Kapur R, Zeng LF, Zhang ZY, Feng GS, Hartmann K, Roers A, Craig AW.

Mol Cell Biol. 2012 Jul;32(14):2653-63. doi: 10.1128/MCB.00308-12. Epub 2012 May 7.


FES/FER kinase signaling in hematopoietic cells and leukemias.

Craig AW.

Front Biosci (Landmark Ed). 2012 Jan 1;17:861-75. Review.


The PI3K pathway drives the maturation of mast cells via microphthalmia transcription factor.

Ma P, Mali RS, Munugalavadla V, Krishnan S, Ramdas B, Sims E, Martin H, Ghosh J, Li S, Chan RJ, Krystal G, Craig AW, Takemoto C, Kapur R.

Blood. 2011 Sep 29;118(13):3459-69. doi: 10.1182/blood-2011-04-351809. Epub 2011 Jul 25.


Cdc42-interacting protein 4 is a Src substrate that regulates invadopodia and invasiveness of breast tumors by promoting MT1-MMP endocytosis.

Hu J, Mukhopadhyay A, Truesdell P, Chander H, Mukhopadhyay UK, Mak AS, Craig AW.

J Cell Sci. 2011 May 15;124(Pt 10):1739-51. doi: 10.1242/jcs.078014. Epub 2011 Apr 26.


Efficacy of atovaquone and azithromycin or imidocarb dipropionate in cats with acute cytauxzoonosis.

Cohn LA, Birkenheuer AJ, Brunker JD, Ratcliff ER, Craig AW.

J Vet Intern Med. 2011 Jan-Feb;25(1):55-60. doi: 10.1111/j.1939-1676.2010.0646.x. Epub 2010 Dec 10.


Transducer of Cdc42-dependent actin assembly promotes epidermal growth factor-induced cell motility and invasiveness.

Hu J, Mukhopadhyay A, Craig AW.

J Biol Chem. 2011 Jan 21;286(3):2261-72. doi: 10.1074/jbc.M110.157974. Epub 2010 Nov 9.


Fps/Fes protein-tyrosine kinase regulates mast cell adhesion and migration downstream of Kit and beta1 integrin receptors.

Smith JA, Samayawardhena LA, Craig AW.

Cell Signal. 2010 Mar;22(3):427-36. doi: 10.1016/j.cellsig.2009.10.014.


SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes Fc epsilon RI-induced activation of Fyn and Erk pathways leading to TNF alpha release from bone marrow-derived mast cells.

McPherson VA, Sharma N, Everingham S, Smith J, Zhu HH, Feng GS, Craig AW.

J Immunol. 2009 Oct 15;183(8):4940-7. doi: 10.4049/jimmunol.0900702. Epub 2009 Sep 28.


F-BAR-containing adaptor CIP4 localizes to early endosomes and regulates Epidermal Growth Factor Receptor trafficking and downregulation.

Hu J, Troglio F, Mukhopadhyay A, Everingham S, Kwok E, Scita G, Craig AW.

Cell Signal. 2009 Nov;21(11):1686-97. doi: 10.1016/j.cellsig.2009.07.007. Epub 2009 Jul 24.


Oppression through acceptance?: predicting rape myth acceptance and attitudes toward rape victims.

Hockett JM, Saucier DA, Hoffman BH, Smith SJ, Craig AW.

Violence Against Women. 2009 Aug;15(8):877-97. doi: 10.1177/1077801209335489. Epub 2009 Jun 8.


Contributions of F-BAR and SH2 domains of Fes protein tyrosine kinase for coupling to the FcepsilonRI pathway in mast cells.

McPherson VA, Everingham S, Karisch R, Smith JA, Udell CM, Zheng J, Jia Z, Craig AW.

Mol Cell Biol. 2009 Jan;29(2):389-401. doi: 10.1128/MCB.00904-08. Epub 2008 Nov 10.


Apolipoprotein(a) stimulates vascular endothelial cell growth and migration and signals through integrin alphaVbeta3.

Liu L, Craig AW, Meldrum HD, Marcovina SM, Elliott BE, Koschinsky ML.

Biochem J. 2009 Mar 1;418(2):325-36. doi: 10.1042/BJ20080744.


Fer and Fps/Fes participate in a Lyn-dependent pathway from FcepsilonRI to platelet-endothelial cell adhesion molecule 1 to limit mast cell activation.

Udell CM, Samayawardhena LA, Kawakami Y, Kawakami T, Craig AW.

J Biol Chem. 2006 Jul 28;281(30):20949-57. Epub 2006 May 26.


Fyn kinase acts upstream of Shp2 and p38 mitogen-activated protein kinase to promote chemotaxis of mast cells towards stem cell factor.

Samayawardhena LA, Hu J, Stein PL, Craig AW.

Cell Signal. 2006 Sep;18(9):1447-54. Epub 2006 Jan 25.


Continuous association of cadherin with beta-catenin requires the non-receptor tyrosine-kinase Fer.

Xu G, Craig AW, Greer P, Miller M, Anastasiadis PZ, Lilien J, Balsamo J.

J Cell Sci. 2004 Jul 1;117(Pt 15):3207-19.


Actin depolymerization-induced tyrosine phosphorylation of cortactin: the role of Fer kinase.

Fan L, Di Ciano-Oliveira C, Weed SA, Craig AW, Greer PA, Rotstein OD, Kapus A.

Biochem J. 2004 Jun 1;380(Pt 2):581-91.


Fps/Fes and Fer protein-tyrosinekinases play redundant roles in regulating hematopoiesis.

Senis YA, Craig AW, Greer PA.

Exp Hematol. 2003 Aug;31(8):673-81.


Fps/Fes and Fer non-receptor protein-tyrosine kinases regulate collagen- and ADP-induced platelet aggregation.

Senis YA, Sangrar W, Zirngibl RA, Craig AW, Lee DH, Greer PA.

J Thromb Haemost. 2003 May;1(5):1062-70.


Absence of Fer protein-tyrosine kinase exacerbates leukocyte recruitment in response to endotoxin.

McCafferty DM, Craig AW, Senis YA, Greer PA.

J Immunol. 2002 May 15;168(10):4930-5.


Translational repression by a novel partner of human poly(A) binding protein, Paip2.

Khaleghpour K, Svitkin YV, Craig AW, DeMaria CT, Deo RC, Burley SK, Sonenberg N.

Mol Cell. 2001 Jan;7(1):205-16.


Mice devoid of fer protein-tyrosine kinase activity are viable and fertile but display reduced cortactin phosphorylation.

Craig AW, Zirngibl R, Williams K, Cole LA, Greer PA.

Mol Cell Biol. 2001 Jan;21(2):603-13.


Mutation of a highly conserved aspartate residue in subdomain IX abolishes Fer protein-tyrosine kinase activity.

Cole LA, Zirngibl R, Craig AW, Jia Z, Greer P.

Protein Eng. 1999 Feb;12(2):155-62.


Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation.

Craig AW, Haghighat A, Yu AT, Sonenberg N.

Nature. 1998 Apr 2;392(6675):520-3.


The La autoantigen contains a dimerization domain that is essential for enhancing translation.

Craig AW, Svitkin YV, Lee HS, Belsham GJ, Sonenberg N.

Mol Cell Biol. 1997 Jan;17(1):163-9.

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