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Items: 28

1.
2.

RB mutation and RAS overexpression induce resistance to NK cell-mediated cytotoxicity in glioma cells.

Orozco-Morales M, Sánchez-García FJ, Golán-Cancela I, Hernández-Pedro N, Costoya JA, de la Cruz VP, Moreno-Jiménez S, Sotelo J, Pineda B.

Cancer Cell Int. 2015 Jun 5;15:57. doi: 10.1186/s12935-015-0209-x. eCollection 2015.

3.

Lipoprotein internalisation induced by oncogenic AMPK activation is essential to maintain glioblastoma cell growth.

Ríos M, Foretz M, Viollet B, Prieto A, Fraga M, García-Caballero T, Costoya JA, Señarís R.

Eur J Cancer. 2014 Dec;50(18):3187-97. doi: 10.1016/j.ejca.2014.09.014. Epub 2014 Oct 13.

PMID:
25450947
4.

The antimitotic potential of PARP inhibitors, an unexplored therapeutic alternative.

Iglesias P, Costoya JA.

Curr Top Med Chem. 2014;14(20):2346-65. Review.

PMID:
25434352
5.

Fluorescent drug-loaded, polymeric-based, branched gold nanoshells for localized multimodal therapy and imaging of tumoral cells.

Topete A, Alatorre-Meda M, Iglesias P, Villar-Alvarez EM, Barbosa S, Costoya JA, Taboada P, Mosquera V.

ACS Nano. 2014 Mar 25;8(3):2725-38. doi: 10.1021/nn406425h. Epub 2014 Mar 3.

PMID:
24571629
6.

AMPK activation by oncogenesis is required to maintain cancer cell proliferation in astrocytic tumors.

Ríos M, Foretz M, Viollet B, Prieto A, Fraga M, Costoya JA, Señarís R.

Cancer Res. 2013 Apr 15;73(8):2628-38. doi: 10.1158/0008-5472.CAN-12-0861. Epub 2013 Jan 31.

7.

Defining hypoxic microenvironments by non-invasive functional optical imaging.

Iglesias P, Fraga M, Costoya JA.

Eur J Cancer. 2013 Jan;49(1):264-71. doi: 10.1016/j.ejca.2012.06.001. Epub 2012 Jul 3.

PMID:
22766514
8.

The maintenance of mitochondrial genetic stability is crucial during the oncogenic process.

Iglesias P, Salas A, Costoya JA.

Commun Integr Biol. 2012 Jan 1;5(1):34-8.

9.

The mitochondrial genome is a "genetic sanctuary" during the oncogenic process.

Seoane M, Mosquera-Miguel A, Gonzalez T, Fraga M, Salas A, Costoya JA.

PLoS One. 2011;6(8):e23327. doi: 10.1371/journal.pone.0023327. Epub 2011 Aug 17.

10.

Resistance of neonatal primary astrocytes against Fas-induced apoptosis depends on silencing of caspase 8.

Barca O, Carneiro C, Costoya JA, Señarís RM, Arce VM.

Neurosci Lett. 2010 Aug 2;479(3):206-10. doi: 10.1016/j.neulet.2010.05.057. Epub 2010 May 25.

PMID:
20510339
11.

A novel BRET-based genetically encoded biosensor for functional imaging of hypoxia.

Iglesias P, Costoya JA.

Biosens Bioelectron. 2009 Jun 15;24(10):3126-30. doi: 10.1016/j.bios.2009.04.013. Epub 2009 Apr 16.

PMID:
19423327
12.

Retinoblastoma loss modulates DNA damage response favoring tumor progression.

Seoane M, Iglesias P, Gonzalez T, Dominguez F, Fraga M, Aliste C, Forteza J, Costoya JA.

PLoS One. 2008;3(11):e3632. doi: 10.1371/journal.pone.0003632. Epub 2008 Nov 5.

13.

Interferon-beta protects astrocytes against tumour necrosis factor-induced apoptosis via activation of p38 mitogen-activated protein kinase.

Barca O, Costoya JA, Señarís RM, Arce VM.

Exp Cell Res. 2008 Jul 1;314(11-12):2231-7. doi: 10.1016/j.yexcr.2008.04.005. Epub 2008 Apr 22.

PMID:
18501892
14.

Cyclin-dependent kinase antagonizes promyelocytic leukemia zinc-finger through phosphorylation.

Costoya JA, Hobbs RM, Pandolfi PP.

Oncogene. 2008 Jun 19;27(27):3789-96. doi: 10.1038/onc.2008.7. Epub 2008 Feb 4.

PMID:
18246121
15.

Functional analysis of the role of POK transcriptional repressors.

Costoya JA.

Brief Funct Genomic Proteomic. 2007 Mar;6(1):8-18. Epub 2007 Mar 24. Review.

PMID:
17384421
16.
17.

Essential role of Plzf in maintenance of spermatogonial stem cells.

Costoya JA, Hobbs RM, Barna M, Cattoretti G, Manova K, Sukhwani M, Orwig KE, Wolgemuth DJ, Pandolfi PP.

Nat Genet. 2004 Jun;36(6):653-9. Epub 2004 May 23.

18.

Plzf mediates transcriptional repression of HoxD gene expression through chromatin remodeling.

Barna M, Merghoub T, Costoya JA, Ruggero D, Branford M, Bergia A, Samori B, Pandolfi PP.

Dev Cell. 2002 Oct;3(4):499-510.

19.

Activation of human somatostatin receptor 2 promotes apoptosis through a mechanism that is independent from induction of p53.

Teijeiro R, Rios R, Costoya JA, Castro R, Bello JL, Devesa J, Arce VM.

Cell Physiol Biochem. 2002;12(1):31-8.

20.

The role of promyelocytic leukemia zinc finger and promyelocytic leukemia in leukemogenesis and development.

Costoya JA, Pandolfi PP.

Curr Opin Hematol. 2001 Jul;8(4):212-7. Review.

PMID:
11561158
21.

Role of growth hormone receptor in HL-60 cell survival.

Costoya JA, Ríos R, García-Barros M, Gallego R, García-Caballero T, Señarís R, Arce VM, Devesa J.

Mol Cell Biol Res Commun. 2000 Jul;4(1):26-31.

PMID:
11152624
22.

N-glycosylated variants of growth hormone in human pituitary extracts.

García-Barros M, Costoya JA, Ríos R, Arce V, Devesa J.

Horm Res. 2000;53(1):40-5.

PMID:
10965220
23.

Expression of growth hormone receptor in the human brain.

Castro JR, Costoya JA, Gallego R, Prieto A, Arce VM, Señarís R.

Neurosci Lett. 2000 Mar 10;281(2-3):147-50.

PMID:
10704764
24.

Activation of growth hormone receptor delivers an antiapoptotic signal: evidence for a role of Akt in this pathway.

Costoya JA, Finidori J, Moutoussamy S, Seãris R, Devesa J, Arce VM.

Endocrinology. 1999 Dec;140(12):5937-43.

PMID:
10579361
25.

Salivary gland is capable of GH synthesis under GHRH stimulation.

Tresguerres JA, Ariznavarreta C, Granados B, Costoya JA, Pérez-Romero A, Salamé F, Hermanussen M.

J Endocrinol. 1999 Feb;160(2):217-22.

26.

Pattern of presentation of the human growth hormone variant (hGH-V) gene in the normal population.

Costoya JA, Arce V, Devesa J.

J Pediatr Endocrinol Metab. 1998 Sep-Oct;11(5):591-5.

PMID:
9829209
27.

Correlation of Pit-1 gene expression and Pit-1 content with proliferation and differentiation in human myeloid leukemic cells.

Costoya JA, García-Barros M, Gallego R, Señarís R, Arce VM, Devesa J.

Exp Cell Res. 1998 Nov 25;245(1):132-6.

PMID:
9828108
28.

Expression of the human growth hormone normal gene (hGH-N) in proliferating and differentiated HL-60 cells.

Costoya JA, Vidal A, García-Barros M, Arce V, Devesa J.

Exp Cell Res. 1996 Oct 10;228(1):164-7.

PMID:
8892984

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