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Items: 45

1.

A Large-Scale RNAi Screen Identifies SGK1 as a Key Survival Kinase for GBM Stem Cells.

Kulkarni S, Goel-Bhattacharya S, Sengupta S, Cochran BH.

Mol Cancer Res. 2018 Jan;16(1):103-114. doi: 10.1158/1541-7786.MCR-17-0146. Epub 2017 Oct 9.

PMID:
28993509
2.

Regulation of the JMJD3 (KDM6B) histone demethylase in glioblastoma stem cells by STAT3.

Sherry-Lynes MM, Sengupta S, Kulkarni S, Cochran BH.

PLoS One. 2017 Apr 6;12(4):e0174775. doi: 10.1371/journal.pone.0174775. eCollection 2017.

3.

Clinically relevant doses of chemotherapy agents reversibly block formation of glioblastoma neurospheres.

Mihaliak AM, Gilbert CA, Li L, Daou MC, Moser RP, Reeves A, Cochran BH, Ross AH.

Cancer Lett. 2010 Oct 28;296(2):168-77. doi: 10.1016/j.canlet.2010.04.005.

4.

Haploid genetic screens in human cells identify host factors used by pathogens.

Carette JE, Guimaraes CP, Varadarajan M, Park AS, Wuethrich I, Godarova A, Kotecki M, Cochran BH, Spooner E, Ploegh HL, Brummelkamp TR.

Science. 2009 Nov 27;326(5957):1231-5. doi: 10.1126/science.1178955.

5.

STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells.

Sherry MM, Reeves A, Wu JK, Cochran BH.

Stem Cells. 2009 Oct;27(10):2383-92. doi: 10.1002/stem.185.

6.

PDGF-induced human airway smooth muscle cell proliferation requires STAT3 and the small GTPase Rac1.

Simeone-Penney MC, Severgnini M, Rozo L, Takahashi S, Cochran BH, Simon AR.

Am J Physiol Lung Cell Mol Physiol. 2008 Apr;294(4):L698-704. doi: 10.1152/ajplung.00529.2007. Epub 2008 Feb 29.

7.
8.

5-HT induction of c-fos gene expression requires reactive oxygen species and Rac1 and Ras GTPases.

Simon AR, Severgnini M, Takahashi S, Rozo L, Andrahbi B, Agyeman A, Cochran BH, Day RM, Fanburg BL.

Cell Biochem Biophys. 2005;42(3):263-76.

PMID:
15976459
9.

Shiga toxins activate translational regulation pathways in intestinal epithelial cells.

Colpoys WE, Cochran BH, Carducci TM, Thorpe CM.

Cell Signal. 2005 Jul;17(7):891-9. Epub 2004 Dec 24.

PMID:
15763431
10.

Inhibition of the Src and Jak kinases protects against lipopolysaccharide-induced acute lung injury.

Severgnini M, Takahashi S, Tu P, Perides G, Homer RJ, Jhung JW, Bhavsar D, Cochran BH, Simon AR.

Am J Respir Crit Care Med. 2005 Apr 15;171(8):858-67. Epub 2005 Jan 21.

PMID:
15665321
11.

Activation of the STAT pathway in acute lung injury.

Severgnini M, Takahashi S, Rozo LM, Homer RJ, Kuhn C, Jhung JW, Perides G, Steer M, Hassoun PM, Fanburg BL, Cochran BH, Simon AR.

Am J Physiol Lung Cell Mol Physiol. 2004 Jun;286(6):L1282-92. Epub 2004 Jan 16.

12.

Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells.

Konnikova L, Kotecki M, Kruger MM, Cochran BH.

BMC Cancer. 2003 Sep 17;3:23.

13.

Shiga toxin 1 triggers a ribotoxic stress response leading to p38 and JNK activation and induction of apoptosis in intestinal epithelial cells.

Smith WE, Kane AV, Campbell ST, Acheson DW, Cochran BH, Thorpe CM.

Infect Immun. 2003 Mar;71(3):1497-504.

14.

Role of the JAK-STAT pathway in PDGF-stimulated proliferation of human airway smooth muscle cells.

Simon AR, Takahashi S, Severgnini M, Fanburg BL, Cochran BH.

Am J Physiol Lung Cell Mol Physiol. 2002 Jun;282(6):L1296-304.

15.
16.

Regulation of STAT3 by direct binding to the Rac1 GTPase.

Simon AR, Vikis HG, Stewart S, Fanburg BL, Cochran BH, Guan KL.

Science. 2000 Oct 6;290(5489):144-7.

17.
18.

Isolation and characterization of a near-haploid human cell line.

Kotecki M, Reddy PS, Cochran BH.

Exp Cell Res. 1999 Nov 1;252(2):273-80.

PMID:
10527618
19.

p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function.

Grammatikakis N, Lin JH, Grammatikakis A, Tsichlis PN, Cochran BH.

Mol Cell Biol. 1999 Mar;19(3):1661-72.

20.

Activation of the JAK-STAT pathway by reactive oxygen species.

Simon AR, Rai U, Fanburg BL, Cochran BH.

Am J Physiol. 1998 Dec;275(6 Pt 1):C1640-52.

PMID:
9843726
21.
22.

TFII-I enhances activation of the c-fos promoter through interactions with upstream elements.

Kim DW, Cheriyath V, Roy AL, Cochran BH.

Mol Cell Biol. 1998 Jun;18(6):3310-20.

23.

Growth hormone induces a DNA binding factor related to the interferon-stimulated 91-kDa transcription factor.

Meyer DJ, Campbell GS, Cochran BH, Argetsinger LS, Larner AC, Finbloom DS, Carter-Su C, Schwartz J.

J Biol Chem. 1994 Feb 18;269(7):4701-4.

24.

The serum response element can mediate induction of c-fos by growth hormone.

Meyer DJ, Stephenson EW, Johnson L, Cochran BH, Schwartz J.

Proc Natl Acad Sci U S A. 1993 Jul 15;90(14):6721-5.

25.

Coordinate expression of c-fos and jun B is induced in the rat striatum by cocaine.

Moratalla R, Vickers EA, Robertson HA, Cochran BH, Graybiel AM.

J Neurosci. 1993 Feb;13(2):423-33.

26.

Regulation of immediate early gene expression.

Cochran BH.

NIDA Res Monogr. 1993;125:3-24. Review.

PMID:
8341367
27.

MAT alpha 1 can mediate gene activation by a-mating factor.

Sengupta P, Cochran BH.

Genes Dev. 1991 Oct;5(10):1924-34.

28.

The PRE and PQ box are functionally distinct yeast pheromone response elements.

Sengupta P, Cochran BH.

Mol Cell Biol. 1990 Dec;10(12):6809-12.

29.

The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter.

Wagner BJ, Hayes TE, Hoban CJ, Cochran BH.

EMBO J. 1990 Dec;9(13):4477-84.

30.

Rapid events in growth hormone action. Induction of c-fos and c-jun transcription in 3T3-F442A preadipocytes.

Gurland G, Ashcom G, Cochran BH, Schwartz J.

Endocrinology. 1990 Dec;127(6):3187-95.

PMID:
2123448
31.

Identification of a PDGF-responsive element in the murine c-myc gene.

Sacca R, Cochran BH.

Oncogene. 1990 Oct;5(10):1499-505.

PMID:
2250909
32.
33.

Transcriptional regulation of competence genes in Balb/c-3T3 cells.

Cochran BH, Townes J, Hayes TE.

Prog Clin Biol Res. 1988;284:225-41. No abstract available.

PMID:
3064103
34.

Inducible binding of a factor to the c-fos regulatory region.

Hayes TE, Kitchen AM, Cochran BH.

Proc Natl Acad Sci U S A. 1987 Mar;84(5):1272-6.

35.

A rapidly inducible DNA-binding activity which binds upstream of the c-fos proto-oncogene.

Hayes TE, Kitchen AM, Cochran BH.

J Cell Physiol Suppl. 1987;Suppl 5:63-8.

PMID:
3119603
36.

Differential colony hybridization: molecular cloning from a zero data base.

Cochran BH, Zumstein P, Zullo J, Rollins B, Mercola M, Stiles CD.

Methods Enzymol. 1987;147:64-85. No abstract available.

PMID:
2444861
37.
38.

The PDGF-inducible 'competence genes': intracellular mediators of the mitogenic response.

Callahan M, Cochran BH, Stiles CD.

Ciba Found Symp. 1985;116:87-97.

PMID:
4075904
39.

The molecular action of platelet-derived growth factor.

Cochran BH.

Adv Cancer Res. 1985;45:183-216. Review. No abstract available.

PMID:
3004121
40.

Expression of the c-fos gene and of an fos-related gene is stimulated by platelet-derived growth factor.

Cochran BH, Zullo J, Verma IM, Stiles CD.

Science. 1984 Nov 30;226(4678):1080-2. Erratum in: Science 1986 Apr 18;232(4748):307.

PMID:
6093261
41.

Functional role for c-myc in mitogenic response to platelet-derived growth factor.

Armelin HA, Armelin MC, Kelly K, Stewart T, Leder P, Cochran BH, Stiles CD.

Nature. 1984 Aug 23-29;310(5979):655-60.

PMID:
6088986
42.

Regulation of gene expression by serum and serum growth factors.

Hendrickson SL, Cochran BH, Reffel AC, Stiles CD.

Symp Fundam Cancer Res. 1984;37:71-85. No abstract available.

PMID:
6335592
43.

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor.

Kelly K, Cochran BH, Stiles CD, Leder P.

Cell. 1983 Dec;35(3 Pt 2):603-10.

PMID:
6606489
44.

Molecular cloning of gene sequences regulated by platelet-derived growth factor.

Cochran BH, Reffel AC, Stiles CD.

Cell. 1983 Jul;33(3):939-47.

PMID:
6872001
45.

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