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Items: 1 to 50 of 214

1.

Modality-specific peripheral antinociceptive effects of μ-opioid agonists on heat and mechanical stimuli: Contribution of sigma-1 receptors.

Montilla-García Á, Perazzoli G, Tejada MÁ, González-Cano R, Sánchez-Fernández C, Cobos EJ, Baeyens JM.

Neuropharmacology. 2018 Mar 24;135:328-342. doi: 10.1016/j.neuropharm.2018.03.025. [Epub ahead of print]

2.

Resolution of Diffuse Alveolar Haemorrhage after Rituximab therapy.

Parekh A, Garcia-Pacheco R, Natarajan P, Cobos E.

QJM. 2018 Mar 7. doi: 10.1093/qjmed/hcy049. [Epub ahead of print] No abstract available.

PMID:
29522158
3.

Unmasking a Case of Asymptomatic Charcot-Marie-Tooth Disease (CMT1A) With Vincristine.

Jariwal R, Shoua B, Sabetian K, Natarajan P, Cobos E.

J Investig Med High Impact Case Rep. 2018 Feb 26;6:2324709618758349. doi: 10.1177/2324709618758349. eCollection 2018 Jan-Dec.

4.

Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia.

Venter F, Heidari A, Viehweg M, Rivera M, Natarajan P, Cobos E.

J Investig Med High Impact Case Rep. 2018 Feb 15;6:2324709618758348. doi: 10.1177/2324709618758348. eCollection 2018 Jan-Dec.

5.

Targeting immune-driven opioid analgesia by sigma-1 receptors: Opening the door to novel perspectives for the analgesic use of sigma-1 antagonists.

Tejada MÁ, Montilla-García Á, González-Cano R, Bravo-Caparrós I, Ruiz-Cantero MC, Nieto FR, Cobos EJ.

Pharmacol Res. 2018 Feb 15. pii: S1043-6618(18)30211-1. doi: 10.1016/j.phrs.2018.02.008. [Epub ahead of print]

PMID:
29454675
6.

Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling.

Cobos EJ, Nickerson CA, Gao F, Chandran V, Bravo-Caparrós I, González-Cano R, Riva P, Andrews NA, Latremoliere A, Seehus CR, Perazzoli G, Nieto FR, Joller N, Painter MW, Ma CHE, Omura T, Chesler EJ, Geschwind DH, Coppola G, Rangachari M, Woolf CJ, Costigan M.

Cell Rep. 2018 Jan 30;22(5):1301-1312. doi: 10.1016/j.celrep.2018.01.006.

7.

Approaching the thermodynamic view of protein folding through the reproduction of Anfinsen's experiment by undergraduate physical biochemistry students.

Fernandez-Reche A, Cobos ES, Luque I, Ruiz-Sanz J, Martinez JC.

Biochem Mol Biol Educ. 2018 Jan 4. doi: 10.1002/bmb.21107. [Epub ahead of print]

PMID:
29314649
8.

(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties.

Amata E, Rescifina A, Prezzavento O, Arena E, Dichiara M, Pittalà V, Montilla-García Á, Punzo F, Merino P, Cobos EJ, Marrazzo A.

J Med Chem. 2018 Jan 11;61(1):372-384. doi: 10.1021/acs.jmedchem.7b01584. Epub 2017 Dec 20.

PMID:
29220177
9.

Prognostic Factors and Decision Tree for Long-term Survival in Metastatic Uveal Melanoma.

Lorenzo D, Ochoa M, Piulats JM, Gutiérrez C, Arias L, Català J, Grau M, Peñafiel J, Cobos E, Garcia-Bru P, Rubio MJ, Padrón-Pérez N, Dias B, Pera J, Caminal JM.

Cancer Res Treat. 2017 Dec 4. doi: 10.4143/crt.2017.171. [Epub ahead of print]

10.

Association between CFH, CFB, ARMS2, SERPINF1, VEGFR1 and VEGF polymorphisms and anatomical and functional response to ranibizumab treatment in neovascular age-related macular degeneration.

Cobos E, Recalde S, Anter J, Hernandez-Sanchez M, Barreales C, Olavarrieta L, Valverde A, Suarez-Figueroa M, Cruz F, Abraldes M, Pérez-Pérez J, Fernández-Robredo P, Arias L, García-Layana A.

Acta Ophthalmol. 2018 Mar;96(2):e201-e212. doi: 10.1111/aos.13519. Epub 2017 Sep 19.

PMID:
28926193
11.

Grip strength in mice with joint inflammation: A rheumatology function test sensitive to pain and analgesia.

Montilla-García Á, Tejada MÁ, Perazzoli G, Entrena JM, Portillo-Salido E, Fernández-Segura E, Cañizares FJ, Cobos EJ.

Neuropharmacology. 2017 Oct;125:231-242. doi: 10.1016/j.neuropharm.2017.07.029. Epub 2017 Jul 29.

12.

Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice.

Tejada MA, Montilla-García A, Cronin SJ, Cikes D, Sánchez-Fernández C, González-Cano R, Ruiz-Cantero MC, Penninger JM, Vela JM, Baeyens JM, Cobos EJ.

Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8396-8401. doi: 10.1073/pnas.1620068114. Epub 2017 Jul 17.

13.

DOME-SHAPED MACULA IN MYOPIC EYES: Twelve-Month Follow-up.

Lorenzo D, Arias L, Choudhry N, Millan E, Flores I, Rubio MJ, Cobos E, García-Bru P, Filloy A, Caminal JM.

Retina. 2017 Apr;37(4):680-686. doi: 10.1097/IAE.0000000000001222.

PMID:
28333783
14.

Sigma-1 Receptor Antagonists: A New Class of Neuromodulatory Analgesics.

Sánchez-Fernández C, Entrena JM, Baeyens JM, Cobos EJ.

Adv Exp Med Biol. 2017;964:109-132. doi: 10.1007/978-3-319-50174-1_9. Review.

PMID:
28315268
15.

Reply.

Cobos E.

Retina. 2017 May;37(5):e60. doi: 10.1097/IAE.0000000000001609. No abstract available.

PMID:
28301343
16.

Mild Social Stress in Mice Produces Opioid-Mediated Analgesia in Visceral but Not Somatic Pain States.

Pitcher MH, Gonzalez-Cano R, Vincent K, Lehmann M, Cobos EJ, Coderre TJ, Baeyens JM, Cervero F.

J Pain. 2017 Jun;18(6):716-725. doi: 10.1016/j.jpain.2017.02.422. Epub 2017 Feb 20.

17.

Choroidal haemangioma and photodynamic therapy. Anatomical and functional response of patients with choroidal hemangioma treated with photodynamic therapy.

Subirà O, Brosa H, Lorenzo-Parra D, Arias-Barquet L, Català-Mora J, Cobos E, Garcia-Bru P, Rubio-Caso MJ, Caminal-Mitjana JM.

Arch Soc Esp Oftalmol. 2017 Jun;92(6):257-264. doi: 10.1016/j.oftal.2016.11.013. Epub 2016 Dec 23. English, Spanish.

PMID:
28017484
18.

Sigma-1 Receptor Agonism Promotes Mechanical Allodynia After Priming the Nociceptive System with Capsaicin.

Entrena JM, Sánchez-Fernández C, Nieto FR, González-Cano R, Yeste S, Cobos EJ, Baeyens JM.

Sci Rep. 2016 Nov 25;6:37835. doi: 10.1038/srep37835.

19.

(+)-and (-)-Phenazocine enantiomers: Evaluation of their dual opioid agonist/σ1 antagonist properties and antinociceptive effects.

Prezzavento O, Arena E, Sánchez-Fernández C, Turnaturi R, Parenti C, Marrazzo A, Catalano R, Amata E, Pasquinucci L, Cobos EJ.

Eur J Med Chem. 2017 Jan 5;125:603-610. doi: 10.1016/j.ejmech.2016.09.077. Epub 2016 Sep 26.

PMID:
27721146
20.

INCIDENCE AND RELATION WITH ANATOMICAL AND FUNCTIONAL VARIABLES OF POSTOPERATIVE MACULAR DISPLACEMENT IN RHEGMATOGENOUS RETINAL DETACHMENT.

Cobos E, Rubio MJ, Arias L, Caminal JM, Garcia-Bru P, Català J, Jordan S, Vidal M, Gutiérrez L.

Retina. 2016 May;36(5):957-61. doi: 10.1097/IAE.0000000000000807.

PMID:
27115857
21.

Tumor Volumes in Choroidal Melanoma: Agreement Between Three-Dimensional Ultrasound and Two Mathematical Models.

Caminal JM, Mejía K, Arias L, Masuet-Aumatell C, Larrucea-Maseda J, Modolell I, Lorenzo D, Català J, Rubio M, Cobos E, Garcia-Bru P, Flores I, Filloy A, Arruga J.

Am J Ophthalmol. 2016 Jun;166:181-188. doi: 10.1016/j.ajo.2016.03.046. Epub 2016 Apr 8.

PMID:
27066723
22.

[Swept-source OCT imaging of an optic pit].

Jordán S, Lorenzo D, Cobos E.

J Fr Ophtalmol. 2016 Jan;39(1):116-7. doi: 10.1016/j.jfo.2015.03.027. Epub 2015 Nov 29. French. No abstract available.

23.

Nuclear Export as a Novel Therapeutic Target: The CRM1 Connection.

Lu C, Figueroa JA, Liu Z, Konala V, Aulakh A, Verma R, Cobos E, Chiriva-Internati M, Gao W.

Curr Cancer Drug Targets. 2015;15(7):575-92. Review.

PMID:
26324128
24.

Spiritual Coping: A Gateway to Enhancing Family Communication During Cancer Treatment.

Prouty AM, Fischer J, Purdom A, Cobos E, Helmeke KB.

J Relig Health. 2016 Feb;55(1):269-87. doi: 10.1007/s10943-015-0108-4.

PMID:
26311053
25.

Treatment of Hepatic Epithelioid Hemangioendothelioma: Finding Uses for Thalidomide in a New Era of Medicine.

Soape MP, Verma R, Payne JD, Wachtel M, Hardwicke F, Cobos E.

Case Rep Gastrointest Med. 2015;2015:326795. doi: 10.1155/2015/326795. Epub 2015 Jun 17.

26.

Use of Very-Low-Dose Methadone and Haloperidol for Pain Control in Palliative Care Patients: Are the Sigma-1 Receptors Involved?

Cobos EJ, Baeyens JM.

J Palliat Med. 2015 Aug;18(8):660. doi: 10.1089/jpm.2015.0147. Epub 2015 Jun 18. No abstract available.

PMID:
26087240
27.

INTRAVITREAL DEXAMETHASONE IMPLANT FOR RADIATION MACULOPATHY SECONDARY TO PLAQUE BRACHYTHERAPY IN CHOROIDAL MELANOMA.

Caminal JM, Flores-Moreno I, Arias L, Gutiérrez C, Piulats JM, Català J, Rubio MJ, Cobos E, García P, Pera J, Giralt J, Arruga J.

Retina. 2015 Sep;35(9):1890-7. doi: 10.1097/IAE.0000000000000537.

PMID:
26035401
28.

Dexamethasone intravitreal implants for diabetic macular edema refractory to ranibizumab monotherapy or combination therapy.

Gutiérrez-Benítez L, Millan E, Arias L, Garcia P, Cobos E, Caminal M.

Arch Soc Esp Oftalmol. 2015 Oct;90(10):475-80. doi: 10.1016/j.oftal.2015.04.003. Epub 2015 May 23. English, Spanish.

PMID:
26008920
29.

Sigma-1 receptor and inflammatory pain.

Gris G, Cobos EJ, Zamanillo D, Portillo-Salido E.

Inflamm Res. 2015 Jun;64(6):377-81. doi: 10.1007/s00011-015-0819-8. Epub 2015 Apr 23. Review.

PMID:
25902777
30.

Targeting Tumor Initiating Cells through Inhibition of Cancer Testis Antigens and Notch Signaling: A Hypothesis.

Colombo M, Mirandola L, Reidy A, Suvorava N, Konala V, Chiaramonte R, Grizzi F, Rahman RL, Jenkins MR, Nugyen DD, Dalhbeck S, Cobos E, Figueroa JA, Chiriva-Internati M.

Int Rev Immunol. 2015 Mar;34(2):188-99. doi: 10.3109/08830185.2015.1027629. Review.

31.

Chimeric antigen receptor engineering: a right step in the evolution of adoptive cellular immunotherapy.

Figueroa JA, Reidy A, Mirandola L, Trotter K, Suvorava N, Figueroa A, Konala V, Aulakh A, Littlefield L, Grizzi F, Rahman RL, Jenkins MR, Musgrove B, Radhi S, D'Cunha N, D'Cunha LN, Hermonat PL, Cobos E, Chiriva-Internati M.

Int Rev Immunol. 2015 Mar;34(2):154-87. doi: 10.3109/08830185.2015.1018419. Review.

PMID:
25901860
32.

Cancer-testis antigens and immunotherapy in the light of cancer complexity.

Grizzi F, Mirandola L, Qehajaj D, Cobos E, Figueroa JA, Chiriva-Internati M.

Int Rev Immunol. 2015 Mar;34(2):143-53. doi: 10.3109/08830185.2015.1018418. Review.

PMID:
25901859
33.

Sex-driven differences in immunological responses: challenges and opportunities for the immunotherapies of the third millennium.

Mirandola L, Wade R, Verma R, Pena C, Hosiriluck N, Figueroa JA, Cobos E, Jenkins MR, Chiriva-Internati M.

Int Rev Immunol. 2015 Mar;34(2):134-42. doi: 10.3109/08830185.2015.1018417. Review.

PMID:
25901858
34.

The clinical heterogeneity of coenzyme Q10 deficiency results from genotypic differences in the Coq9 gene.

Luna-Sánchez M, Díaz-Casado E, Barca E, Tejada MÁ, Montilla-García Á, Cobos EJ, Escames G, Acuña-Castroviejo D, Quinzii CM, López LC.

EMBO Mol Med. 2015 May;7(5):670-87. doi: 10.15252/emmm.201404632.

35.

Novel antigens in non-small cell lung cancer: SP17, AKAP4, and PTTG1 are potential immunotherapeutic targets.

Mirandola L, Figueroa JA, Phan TT, Grizzi F, Kim M, Rahman RL, Jenkins MR, Cobos E, Jumper C, Alalawi R, Chiriva-Internati M.

Oncotarget. 2015 Feb 20;6(5):2812-26.

36.

Correction: Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity.

Chiu IM, Barrett LB, Williams EK, Strochlic DE, Lee S, Weyer AD, Lou S, Bryman G, Roberson DP, Ghasemlou N, Piccoli C, Ahat E, Wang V, Cobos EJ, Stucky CL, Ma Q, Liberles SD, Woolf C.

Elife. 2015 Feb 6;4:e06720. doi: 10.7554/eLife.06720. No abstract available.

37.

WW domains of the yes-kinase-associated-protein (YAP) transcriptional regulator behave as independent units with different binding preferences for PPxY motif-containing ligands.

Iglesias-Bexiga M, Castillo F, Cobos ES, Oka T, Sudol M, Luque I.

PLoS One. 2015 Jan 21;10(1):e0113828. doi: 10.1371/journal.pone.0113828. eCollection 2015.

38.

Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity.

Chiu IM, Barrett LB, Williams EK, Strochlic DE, Lee S, Weyer AD, Lou S, Bryman GS, Roberson DP, Ghasemlou N, Piccoli C, Ahat E, Wang V, Cobos EJ, Stucky CL, Ma Q, Liberles SD, Woolf CJ.

Elife. 2014 Dec 19;3. doi: 10.7554/eLife.04660. Erratum in: Elife. 2015;4:e06720.

39.

Single-chain protein mimetics of the N-terminal heptad-repeat region of gp41 with potential as anti-HIV-1 drugs.

Crespillo S, Cámara-Artigas A, Casares S, Morel B, Cobos ES, Mateo PL, Mouz N, Martin CE, Roger MG, El Habib R, Su B, Moog C, Conejero-Lara F.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18207-12. doi: 10.1073/pnas.1413592112. Epub 2014 Dec 8.

40.

Galectins in cancer: carcinogenesis, diagnosis and therapy.

Ebrahim AH, Alalawi Z, Mirandola L, Rakhshanda R, Dahlbeck S, Nguyen D, Jenkins M, Grizzi F, Cobos E, Figueroa JA, Chiriva-Internati M.

Ann Transl Med. 2014 Sep;2(9):88. doi: 10.3978/j.issn.2305-5839.2014.09.12. Review.

41.

Galectins as therapeutic targets for hematological malignancies: a hopeful sweetness.

Pena C, Mirandola L, Figueroa JA, Hosiriluck N, Suvorava N, Trotter K, Reidy A, Rakhshanda R, Payne D, Jenkins M, Grizzi F, Littlefield L, Chiriva-Internati M, Cobos E.

Ann Transl Med. 2014 Sep;2(9):87. doi: 10.3978/j.issn.2305-5839.2014.09.14. Review.

42.

Galectin-3 inhibition suppresses drug resistance, motility, invasion and angiogenic potential in ovarian cancer.

Mirandola L, Yu Y, Cannon MJ, Jenkins MR, Rahman RL, Nguyen DD, Grizzi F, Cobos E, Figueroa JA, Chiriva-Internati M.

Gynecol Oncol. 2014 Dec;135(3):573-9. doi: 10.1016/j.ygyno.2014.09.021. Epub 2014 Oct 6.

PMID:
25284038
43.

AAV2/8-hSMAD3 gene delivery attenuates aortic atherogenesis, enhances Th2 response without fibrosis, in LDLR-KO mice on high cholesterol diet.

Zhu H, Cao M, Figueroa JA, Cobos E, Uretsky BF, Chiriva-Internati M, Hermonat PL.

J Transl Med. 2014 Sep 20;12:252. doi: 10.1186/s12967-014-0252-8.

44.

Autofluorescence and axial length as prognostic factors for outcomes of macular hole retinal detachment surgery in high myopia.

Arias L, Caminal JM, Rubio MJ, Cobos E, Garcia-Bru P, Filloy A, Padron N, Mejia K.

Retina. 2015 Mar;35(3):423-8. doi: 10.1097/IAE.0000000000000335.

PMID:
25170859
45.

Diminished Schwann cell repair responses underlie age-associated impaired axonal regeneration.

Painter MW, Brosius Lutz A, Cheng YC, Latremoliere A, Duong K, Miller CM, Posada S, Cobos EJ, Zhang AX, Wagers AJ, Havton LA, Barres B, Omura T, Woolf CJ.

Neuron. 2014 Jul 16;83(2):331-343. doi: 10.1016/j.neuron.2014.06.016.

46.

The impact of extra-domain structures and post-translational modifications in the folding/misfolding behaviour of the third PDZ domain of MAGUK neuronal protein PSD-95.

Murciano-Calles J, Marin-Argany M, Cobos ES, Villegas S, Martinez JC.

PLoS One. 2014 May 20;9(5):e98124. doi: 10.1371/journal.pone.0098124. eCollection 2014.

47.

Selective expression and immunogenicity of the cancer/testis antigens SP17, AKAP4 and PTTG1 in non-small cell lung cancer: new candidates for active immunotherapy.

Chiriva-Internati M, Mirandola L, Figueroa JA, Yu Y, Grizzi F, Kim M, Jenkins M, Cobos E, Jumper C, Alalawi R.

Chest. 2014 May 8. doi: 10.1378/chest.13-0770. [Epub ahead of print]

PMID:
24811938
48.

The role of human papilloma virus (HPV) infection in non-anogenital cancer and the promise of immunotherapy: a review.

Cobos C, Figueroa JA, Mirandola L, Colombo M, Summers G, Figueroa A, Aulakh A, Konala V, Verma R, Riaz J, Wade R, Saadeh C, Rahman RL, Pandey A, Radhi S, Nguyen DD, Jenkins M, Chiriva-Internati M, Cobos E.

Int Rev Immunol. 2014 Oct;33(5):383-401. doi: 10.3109/08830185.2014.911857. Epub 2014 May 8. Review.

PMID:
24811210
49.

Sperm protein 17 is an oncofetal antigen: a lesson from a murine model.

Arnaboldi F, Menon A, Menegola E, Di Renzo F, Mirandola L, Grizzi F, Figueroa JA, Cobos E, Jenkins M, Barajon I, Chiriva-Internati M.

Int Rev Immunol. 2014 Oct;33(5):367-74. doi: 10.3109/08830185.2014.911856. Epub 2014 May 8. Review.

PMID:
24811209
50.

Anti-galectin-3 therapy: a new chance for multiple myeloma and ovarian cancer?

Mirandola L, Nguyen DD, Rahman RL, Grizzi F, Yuefei Y, Figueroa JA, Jenkins MR, Cobos E, Chiriva-Internati M.

Int Rev Immunol. 2014 Oct;33(5):417-27. doi: 10.3109/08830185.2014.911855. Epub 2014 May 6. Review.

PMID:
24801755

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