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Items: 29

1.

Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth.

Pearson HB, Li J, Meniel VS, Fennell CM, Waring P, Montgomery KG, Rebello RJ, Macpherson AA, Koushyar S, Furic L, Cullinane C, Clarkson RW, Smalley MJ, Simpson KJ, Phesse TJ, Shepherd PR, Humbert PO, Sansom OJ, Phillips WA.

Cancer Discov. 2018 Mar 26. doi: 10.1158/2159-8290.CD-17-0867. [Epub ahead of print]

PMID:
29581176
2.

Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells.

Chen HC, Joalland N, Bridgeman JS, Alchami FS, Jarry U, Khan MWA, Piggott L, Shanneik Y, Li J, Herold MJ, Herrmann T, Price DA, Gallimore AM, Clarkson RW, Scotet E, Moser B, Eberl M.

Immunol Cell Biol. 2017 Aug;95(7):620-629. doi: 10.1038/icb.2017.21. Epub 2017 Mar 30.

3.

Erratum to: Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL.

Piggott L, Omidvar N, Martí Pérez S, French R, Eberl M, Clarkson RW.

Breast Cancer Res. 2015 Jul 16;17:96. doi: 10.1186/s13058-015-0597-9. No abstract available.

4.

Developmental programming mediated by complementary roles of imprinted Grb10 in mother and pup.

Cowley M, Garfield AS, Madon-Simon M, Charalambous M, Clarkson RW, Smalley MJ, Kendrick H, Isles AR, Parry AJ, Carney S, Oakey RJ, Heisler LK, Moorwood K, Wolf JB, Ward A.

PLoS Biol. 2014 Feb 25;12(2):e1001799. doi: 10.1371/journal.pbio.1001799. eCollection 2014 Feb.

5.

Bcl3 selectively promotes metastasis of ERBB2-driven mammary tumors.

Wakefield A, Soukupova J, Montagne A, Ranger J, French R, Muller WJ, Clarkson RW.

Cancer Res. 2013 Jan 15;73(2):745-55. doi: 10.1158/0008-5472.CAN-12-1321. Epub 2012 Nov 13.

6.

Evaluation of a fluorescent derivative of AMD3100 and its interaction with the CXCR4 chemokine receptor.

Knight JC, Hallett AJ, Brancale A, Paisey SJ, Clarkson RW, Edwards PG.

Chembiochem. 2011 Nov 25;12(17):2692-8. doi: 10.1002/cbic.201100441. Epub 2011 Oct 13.

PMID:
21998043
7.

Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL.

Piggott L, Omidvar N, Martí Pérez S, French R, Eberl M, Clarkson RW.

Breast Cancer Res. 2011 Sep 14;13(5):R88. doi: 10.1186/bcr2945. Erratum in: Breast Cancer Res. 2015;17:96. French, Rhiannon [added].

8.

Stat3 controls lysosomal-mediated cell death in vivo.

Kreuzaler PA, Staniszewska AD, Li W, Omidvar N, Kedjouar B, Turkson J, Poli V, Flavell RA, Clarkson RW, Watson CJ.

Nat Cell Biol. 2011 Mar;13(3):303-9. doi: 10.1038/ncb2171. Epub 2011 Feb 20.

PMID:
21336304
9.

A dual role for oncostatin M signaling in the differentiation and death of mammary epithelial cells in vivo.

Tiffen PG, Omidvar N, Marquez-Almuina N, Croston D, Watson CJ, Clarkson RW.

Mol Endocrinol. 2008 Dec;22(12):2677-88. doi: 10.1210/me.2008-0097. Epub 2008 Oct 16.

10.

The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development.

Clarkson RW, Boland MP, Kritikou EA, Lee JM, Freeman TC, Tiffen PG, Watson CJ.

Mol Endocrinol. 2006 Mar;20(3):675-85. Epub 2005 Nov 17.

PMID:
16293640
11.

Regulation of genes encoding proteolytic enzymes during mammary gland development.

Sorrell DA, Szymanowska M, Boutinaud M, Robinson C, Clarkson RW, Stein T, Flint DJ, Kolb AF.

J Dairy Res. 2005 Nov;72(4):433-41.

PMID:
16223458
12.

Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition.

Abell K, Bilancio A, Clarkson RW, Tiffen PG, Altaparmakov AI, Burdon TG, Asano T, Vanhaesebroeck B, Watson CJ.

Nat Cell Biol. 2005 Apr;7(4):392-8. Epub 2005 Mar 27.

PMID:
15793565
13.

Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression.

Clarkson RW, Wayland MT, Lee J, Freeman T, Watson CJ.

Breast Cancer Res. 2004;6(2):R92-109. Epub 2003 Dec 18.

14.

Microarray analysis of the involution switch.

Clarkson RW, Watson CJ.

J Mammary Gland Biol Neoplasia. 2003 Jul;8(3):309-19. Review.

PMID:
14973375
15.

A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland.

Kritikou EA, Sharkey A, Abell K, Came PJ, Anderson E, Clarkson RW, Watson CJ.

Development. 2003 Aug;130(15):3459-68.

16.

Gene structure of the human metabotropic glutamate receptor 5 and functional analysis of its multiple promoters in neuroblastoma and astroglioma cells.

Corti C, Clarkson RW, Crepaldi L, Sala CF, Xuereb JH, Ferraguti F.

J Biol Chem. 2003 Aug 29;278(35):33105-19. Epub 2003 Jun 3.

17.

A novel cell culture model for studying differentiation and apoptosis in the mouse mammary gland.

Gordon KE, Binas B, Chapman RS, Kurian KM, Clarkson RW, Clark AJ, Lane EB, Watson CJ.

Breast Cancer Res. 2000;2(3):222-35. Epub 2000 Mar 7.

18.

NF-kappaB inhibits apoptosis in murine mammary epithelia.

Clarkson RW, Heeley JL, Chapman R, Aillet F, Hay RT, Wyllie A, Watson CJ.

J Biol Chem. 2000 Apr 28;275(17):12737-42.

19.

NF-kappaB and apoptosis in mammary epithelial cells.

Clarkson RW, Watson CJ.

J Mammary Gland Biol Neoplasia. 1999 Apr;4(2):165-75. Review.

PMID:
10426395
20.
21.

Growth hormone and insulin-like growth factor I induce bone morphogenetic proteins 2 and 4: a mediator role in bone and tooth formation?

Li H, Bartold PM, Zhang CZ, Clarkson RW, Young WG, Waters MJ.

Endocrinology. 1998 Sep;139(9):3855-62.

PMID:
9724040
22.

Activation of chimeric and full-length growth hormone receptors by growth hormone receptor monoclonal antibodies. A specific conformational change may be required for full-length receptor signaling.

Rowlinson SW, Behncken SN, Rowland JE, Clarkson RW, Strasburger CJ, Wu Z, Baumbach W, Waters MJ.

J Biol Chem. 1998 Feb 27;273(9):5307-14.

23.

Growth factor modulation of mitogenic responses and proteoglycan synthesis by human periodontal fibroblasts.

Haase HR, Clarkson RW, Waters MJ, Bartold PM.

J Cell Physiol. 1998 Mar;174(3):353-61.

PMID:
9462697
24.

Growth hormone and colony-stimulating factor 1 share multiple response elements in the c-fos promoter.

Chen C, Clarkson RW, Xie Y, Hume DA, Waters MJ.

Endocrinology. 1995 Oct;136(10):4505-16.

PMID:
7664671
25.
26.

Signal transduction by the growth hormone receptor.

Waters MJ, Rowlinson SW, Clarkson RW, Chen CM, Lobie PE, Norstedt G, Mertani H, Morel G, Brinkworth R, Wells CA, et al.

Proc Soc Exp Biol Med. 1994 Jul;206(3):216-20. Review.

PMID:
8016156
27.

Major histocompatibility complex variants and articular disease severity in rheumatoid arthritis.

McMahon MJ, Hillarby MC, Clarkson RW, Hollis S, Grennan DM.

Br J Rheumatol. 1993 Oct;32(10):899-902.

PMID:
8401999
28.

HLA associations in subjects with rheumatoid arthritis and bronchiectasis but not with other pulmonary complications of rheumatoid disease.

Hillarby MC, McMahon MJ, Grennan DM, Cooper RG, Clarkson RW, Davies EJ, Sanders PA, Chattopadhyay C, Swinson D.

Br J Rheumatol. 1993 Sep;32(9):794-7.

PMID:
8369890
29.

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