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Genomic perspectives of spider silk genes through target capture sequencing: Conservation of stabilization mechanisms and homology-based structural models of spidroin terminal regions.

Collin MA, Clarke TH 3rd, Ayoub NA, Hayashi CY.

Int J Biol Macromol. 2018 Feb 14;113:829-840. doi: 10.1016/j.ijbiomac.2018.02.032. [Epub ahead of print]


Electron transfer process in microbial electrochemical technologies: The role of cell-surface exposed conductive proteins.

Costa NL, Clarke TA, Philipp LA, Gescher J, Louro RO, Paquete CM.

Bioresour Technol. 2018 May;255:308-317. doi: 10.1016/j.biortech.2018.01.133. Epub 2018 Jan 31. Review.


Genome-wide meta-analyses of stratified depression in Generation Scotland and UK Biobank.

Hall LS, Adams MJ, Arnau-Soler A, Clarke TK, Howard DM, Zeng Y, Davies G, Hagenaars SP, Maria Fernandez-Pujals A, Gibson J, Wigmore EM, Boutin TS, Hayward C, Scotland G; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Porteous DJ, Deary IJ, Thomson PA, Haley CS, McIntosh AM.

Transl Psychiatry. 2018 Jan 10;8(1):9. doi: 10.1038/s41398-017-0034-1.


Nanoparticle size and production efficiency are affected by the presence of fatty acids during albumin nanoparticle fabrication.

Luebbert CC, Clarke TM, Pointet R, Frahm GE, Tam S, Lorbetskie B, Sauvé S, Johnston MJW.

PLoS One. 2017 Dec 27;12(12):e0189814. doi: 10.1371/journal.pone.0189814. eCollection 2017.


Quantitative analysis of antimicrobial use on British dairy farms.

Hyde RM, Remnant JG, Bradley AJ, Breen JE, Hudson CD, Davies PL, Clarke T, Critchell Y, Hylands M, Linton E, Wood E, Green MJ.

Vet Rec. 2017 Dec 23;181(25):683. doi: 10.1136/vr.104614. Epub 2017 Dec 20.


PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression.

Chiang K, Zielinska AE, Shaaban AM, Sanchez-Bailon MP, Jarrold J, Clarke TL, Zhang J, Francis A, Jones LJ, Smith S, Barbash O, Guccione E, Farnie G, Smalley MJ, Davies CC.

Cell Rep. 2017 Dec 19;21(12):3498-3513. doi: 10.1016/j.celrep.2017.11.096.


The 10th anniversary of patient safety in surgery.

Stahel PF, Smith WR, Moore EE, Mehler PS, Weckbach S, Kim FJ, Butler N, Pape HC, Clarke TJ, Makary MA, Clavien PA.

Patient Saf Surg. 2017 Dec 14;11:27. doi: 10.1186/s13037-017-0145-x. eCollection 2017. No abstract available.


Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.

Luciano M, Hagenaars SP, Davies G, Hill WD, Clarke TK, Shirali M, Harris SE, Marioni RE, Liewald DC, Fawns-Ritchie C, Adams MJ, Howard DM, Lewis CM, Gale CR, McIntosh AM, Deary IJ.

Nat Genet. 2018 Jan;50(1):6-11. doi: 10.1038/s41588-017-0013-8. Epub 2017 Dec 18.


Gene3D: Extensive prediction of globular domains in proteins.

Lewis TE, Sillitoe I, Dawson N, Lam SD, Clarke T, Lee D, Orengo C, Lees J.

Nucleic Acids Res. 2018 Jan 4;46(D1):D1282. doi: 10.1093/nar/gkx1187. No abstract available.


Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank.

Howard DM, Hall LS, Hafferty JD, Zeng Y, Adams MJ, Clarke TK, Porteous DJ, Nagy R, Hayward C, Smith BH, Murray AD, Ryan NM, Evans KL, Haley CS, Deary IJ, Thomson PA, McIntosh AM.

Transl Psychiatry. 2017 Nov 30;7(11):1263. doi: 10.1038/s41398-017-0010-9.


The microbiota protects against respiratory infection via GM-CSF signaling.

Brown RL, Sequeira RP, Clarke TB.

Nat Commun. 2017 Nov 15;8(1):1512. doi: 10.1038/s41467-017-01803-x.


Oxidation of Polynuclear Aromatic Hydrocarbons using Ruthenium-Ion-Catalyzed Oxidation: The Role of Aromatic Ring Number in Reaction Kinetics and Product Distribution.

Nowicka E, Clarke TJ, Sankar M, Jenkins RL, Knight DW, Golunski S, Hutchings GJ, Willock DJ, Francisco M, Taylor SH.

Chemistry. 2018 Jan 12;24(3):655-662. doi: 10.1002/chem.201704133. Epub 2017 Dec 11.


Gene3D: Extensive prediction of globular domains in proteins.

Lewis TE, Sillitoe I, Dawson N, Lam SD, Clarke T, Lee D, Orengo C, Lees J.

Nucleic Acids Res. 2018 Jan 4;46(D1):D435-D439. doi: 10.1093/nar/gkx1069.


Polygenic risk for schizophrenia, transition and cortical gyrification: a high-risk study.

Neilson E, Bois C, Clarke TK, Hall L, Johnstone EC, Owens DGC, Whalley HC, McIntosh AM, Lawrie SM.

Psychol Med. 2017 Oct 25:1-11. doi: 10.1017/S0033291717003087. [Epub ahead of print]


Cohort Profile: Stratifying Resilience and Depression Longitudinally (STRADL): a questionnaire follow-up of Generation Scotland: Scottish Family Health Study (GS:SFHS).

Navrady LB, Wolters MK, MacIntyre DJ, Clarke TK, Campbell AI, Murray AD, Evans KL, Seckl J, Haley C, Milburn K, Wardlaw JM, Porteous DJ, Deary IJ, McIntosh AM.

Int J Epidemiol. 2018 Feb 1;47(1):13-14g. doi: 10.1093/ije/dyx115. No abstract available.


A radio counterpart to a neutron star merger.

Hallinan G, Corsi A, Mooley KP, Hotokezaka K, Nakar E, Kasliwal MM, Kaplan DL, Frail DA, Myers ST, Murphy T, De K, Dobie D, Allison JR, Bannister KW, Bhalerao V, Chandra P, Clarke TE, Giacintucci S, Ho AYQ, Horesh A, Kassim NE, Kulkarni SR, Lenc E, Lockman FJ, Lynch C, Nichols D, Nissanke S, Palliyaguru N, Peters WM, Piran T, Rana J, Sadler EM, Singer LP.

Science. 2017 Dec 22;358(6370):1579-1583. doi: 10.1126/science.aap9855. Epub 2017 Oct 16.


Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank.

Howard DM, Adams MJ, Clarke TK, Wigmore EM, Zeng Y, Hagenaars SP, Lyall DM, Thomson PA, Evans KL, Porteous DJ, Nagy R, Hayward C, Haley CS, Smith BH, Murray AD, Batty GD, Deary IJ, McIntosh AM.

Wellcome Open Res. 2017 Aug 10;2:61. doi: 10.12688/wellcomeopenres.12171.1. eCollection 2017.


Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).

Clarke TK, Adams MJ, Davies G, Howard DM, Hall LS, Padmanabhan S, Murray AD, Smith BH, Campbell A, Hayward C, Porteous DJ, Deary IJ, McIntosh AM.

Mol Psychiatry. 2017 Oct;22(10):1376-1384. doi: 10.1038/mp.2017.153. Epub 2017 Jul 25.


The Use of Complementary Health Approaches Among U.S. Adults with a Recent Cancer Diagnosis.

Clarke TC.

J Altern Complement Med. 2018 Feb;24(2):139-145. doi: 10.1089/acm.2016.0182. Epub 2017 Sep 20.


Parity Influences the Demeanor of Sows in Group Housing.

Clarke T, Pluske JR, Miller DW, Collins T, Fleming PA.

J Appl Anim Welf Sci. 2018 Jan-Mar;21(1):17-26. doi: 10.1080/10888705.2017.1363651. Epub 2017 Aug 28.


Transitioning patients with inflammatory bowel disease (IBD) from adolescent to adult services: a systematic review.

Clarke T, Lusher J.

Frontline Gastroenterol. 2016 Oct;7(4):264-270. doi: 10.1136/flgastro-2015-100575. Epub 2015 Jun 16.


Evolutionary shifts in gene expression decoupled from gene duplication across functionally distinct spider silk glands.

Clarke TH, Garb JE, Haney RA, Chaw RC, Hayashi CY, Ayoub NA.

Sci Rep. 2017 Aug 21;7(1):8393. doi: 10.1038/s41598-017-07388-1.


Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19 762), UK Biobank (n=24 048) and the English Longitudinal Study of Ageing (n=5766).

Wigmore EM, Clarke TK, Howard DM, Adams MJ, Hall LS, Zeng Y, Gibson J, Davies G, Fernandez-Pujals AM, Thomson PA, Hayward C, Smith BH, Hocking LJ, Padmanabhan S, Deary IJ, Porteous DJ, Nicodemus KK, McIntosh AM.

Transl Psychiatry. 2017 Aug 15;7(8):e1205. doi: 10.1038/tp.2017.148.


Creating an innovative youth mental health service in the United Kingdom: The Norfolk Youth Service.

Wilson J, Clarke T, Lower R, Ugochukwu U, Maxwell S, Hodgekins J, Wheeler K, Goff A, Mack R, Horne R, Fowler D.

Early Interv Psychiatry. 2017 Aug 4. doi: 10.1111/eip.12452. [Epub ahead of print]


The house spider genome reveals an ancient whole-genome duplication during arachnid evolution.

Schwager EE, Sharma PP, Clarke T, Leite DJ, Wierschin T, Pechmann M, Akiyama-Oda Y, Esposito L, Bechsgaard J, Bilde T, Buffry AD, Chao H, Dinh H, Doddapaneni H, Dugan S, Eibner C, Extavour CG, Funch P, Garb J, Gonzalez LB, Gonzalez VL, Griffiths-Jones S, Han Y, Hayashi C, Hilbrant M, Hughes DST, Janssen R, Lee SL, Maeso I, Murali SC, Muzny DM, Nunes da Fonseca R, Paese CLB, Qu J, Ronshaugen M, Schomburg C, Schönauer A, Stollewerk A, Torres-Oliva M, Turetzek N, Vanthournout B, Werren JH, Wolff C, Worley KC, Bucher G, Gibbs RA, Coddington J, Oda H, Stanke M, Ayoub NA, Prpic NM, Flot JF, Posnien N, Richards S, McGregor AP.

BMC Biol. 2017 Jul 31;15(1):62. doi: 10.1186/s12915-017-0399-x.


Integrating the microbiome as a resource in the forensics toolkit.

Clarke TH, Gomez A, Singh H, Nelson KE, Brinkac LM.

Forensic Sci Int Genet. 2017 Sep;30:141-147. doi: 10.1016/j.fsigen.2017.06.008. Epub 2017 Jun 27.


Prevention and treatment of long-term social disability amongst young people with emerging severe mental illness with social recovery therapy (The PRODIGY Trial): study protocol for a randomised controlled trial.

Fowler D, French P, Banerjee R, Barton G, Berry C, Byrne R, Clarke T, Fraser R, Gee B, Greenwood K, Notley C, Parker S, Shepstone L, Wilson J, Yung AR, Hodgekins J.

Trials. 2017 Jul 11;18(1):315. doi: 10.1186/s13063-017-2062-9.


Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.

Witt SH, Streit F, Jungkunz M, Frank J, Awasthi S, Reinbold CS, Treutlein J, Degenhardt F, Forstner AJ, Heilmann-Heimbach S, Dietl L, Schwarze CE, Schendel D, Strohmaier J, Abdellaoui A, Adolfsson R, Air TM, Akil H, Alda M, Alliey-Rodriguez N, Andreassen OA, Babadjanova G, Bass NJ, Bauer M, Baune BT, Bellivier F, Bergen S, Bethell A, Biernacka JM, Blackwood DHR, Boks MP, Boomsma DI, Børglum AD, Borrmann-Hassenbach M, Brennan P, Budde M, Buttenschøn HN, Byrne EM, Cervantes P, Clarke TK, Craddock N, Cruceanu C, Curtis D, Czerski PM, Dannlowski U, Davis T, de Geus EJC, Di Florio A, Djurovic S, Domenici E, Edenberg HJ, Etain B, Fischer SB, Forty L, Fraser C, Frye MA, Fullerton JM, Gade K, Gershon ES, Giegling I, Gordon SD, Gordon-Smith K, Grabe HJ, Green EK, Greenwood TA, Grigoroiu-Serbanescu M, Guzman-Parra J, Hall LS, Hamshere M, Hauser J, Hautzinger M, Heilbronner U, Herms S, Hitturlingappa S, Hoffmann P, Holmans P, Hottenga JJ, Jamain S, Jones I, Jones LA, Juréus A, Kahn RS, Kammerer-Ciernioch J, Kirov G, Kittel-Schneider S, Kloiber S, Knott SV, Kogevinas M, Landén M, Leber M, Leboyer M, Li QS, Lissowska J, Lucae S, Martin NG, Mayoral-Cleries F, McElroy SL, McIntosh AM, McKay JD, McQuillin A, Medland SE, Middeldorp CM, Milaneschi Y, Mitchell PB, Montgomery GW, Morken G, Mors O, Mühleisen TW, Müller-Myhsok B, Myers RM, Nievergelt CM, Nurnberger JI, O'Donovan MC, Loohuis LMO, Ophoff R, Oruc L, Owen MJ, Paciga SA, Penninx BWJH, Perry A, Pfennig A, Potash JB, Preisig M, Reif A, Rivas F, Rouleau GA, Schofield PR, Schulze TG, Schwarz M, Scott L, Sinnamon GCB, Stahl EA, Strauss J, Turecki G, Van der Auwera S, Vedder H, Vincent JB, Willemsen G, Witt CC, Wray NR, Xi HS; Bipolar Disorders Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Tadic A, Dahmen N, Schott BH, Cichon S, Nöthen MM, Ripke S, Mobascher A, Rujescu D, Lieb K, Roepke S, Schmahl C, Bohus M, Rietschel M.

Transl Psychiatry. 2017 Jun 20;7(6):e1155. doi: 10.1038/tp.2017.115.


Synthesis and Exciton Dynamics of Donor-Orthogonal Acceptor Conjugated Polymers: Reducing the Singlet-Triplet Energy Gap.

Freeman DME, Musser AJ, Frost JM, Stern HL, Forster AK, Fallon KJ, Rapidis AG, Cacialli F, McCulloch I, Clarke TM, Friend RH, Bronstein H.

J Am Chem Soc. 2017 Aug 16;139(32):11073-11080. doi: 10.1021/jacs.7b03327. Epub 2017 Jun 23.


Silk gene expression of theridiid spiders: implications for male-specific silk use.

Correa-Garhwal SM, Chaw RC, Clarke TH 3rd, Ayoub NA, Hayashi CY.

Zoology (Jena). 2017 Jun;122:107-114. doi: 10.1016/j.zool.2017.04.003. Epub 2017 Apr 26.


Predicting response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer with serum biomarkers.

Clarke TL, White DA, Osborne ME, Shaw AM, Smart NJ, Daniels IR.

Ann R Coll Surg Engl. 2017 May;99(5):373-377. doi: 10.1308/rcsann.2017.0030.


Risk and protective factors for structural brain ageing in the eighth decade of life.

Ritchie SJ, Tucker-Drob EM, Cox SR, Dickie DA, Del C Valdés Hernández M, Corley J, Royle NA, Redmond P, Muñoz Maniega S, Pattie A, Aribisala BS, Taylor AM, Clarke TK, Gow AJ, Starr JM, Bastin ME, Wardlaw JM, Deary IJ.

Brain Struct Funct. 2017 Nov;222(8):3477-3490. doi: 10.1007/s00429-017-1414-2. Epub 2017 Apr 19.


Assessing the presence of shared genetic architecture between Alzheimer's disease and major depressive disorder using genome-wide association data.

Gibson J, Russ TC, Adams MJ, Clarke TK, Howard DM, Hall LS, Fernandez-Pujals AM, Wigmore EM, Hayward C, Davies G, Murray AD, Smith BH, Porteous DJ, Deary IJ, McIntosh AM.

Transl Psychiatry. 2017 Apr 18;7(4):e1094. doi: 10.1038/tp.2017.49.


Surgeons, sign your site!

Clarke TJ.

Patient Saf Surg. 2017 Apr 4;11:8. doi: 10.1186/s13037-017-0122-4. eCollection 2017.


Genetic effects influencing risk for major depressive disorder in China and Europe.

Bigdeli TB, Ripke S, Peterson RE, Trzaskowski M, Bacanu SA, Abdellaoui A, Andlauer TF, Beekman AT, Berger K, Blackwood DH, Boomsma DI, Breen G, Buttenschøn HN, Byrne EM, Cichon S, Clarke TK, Couvy-Duchesne B, Craddock N, de Geus EJ, Degenhardt F, Dunn EC, Edwards AC, Fanous AH, Forstner AJ, Frank J, Gill M, Gordon SD, Grabe HJ, Hamilton SP, Hardiman O, Hayward C, Heath AC, Henders AK, Herms S, Hickie IB, Hoffmann P, Homuth G, Hottenga JJ, Ising M, Jansen R, Kloiber S, Knowles JA, Lang M, Li QS, Lucae S, MacIntyre DJ, Madden PA, Martin NG, McGrath PJ, McGuffin P, McIntosh AM, Medland SE, Mehta D, Middeldorp CM, Milaneschi Y, Montgomery GW, Mors O, Müller-Myhsok B, Nauck M, Nyholt DR, Nöthen MM, Owen MJ, Penninx BW, Pergadia ML, Perlis RH, Peyrot WJ, Porteous DJ, Potash JB, Rice JP, Rietschel M, Riley BP, Rivera M, Schoevers R, Schulze TG, Shi J, Shyn SI, Smit JH, Smoller JW, Streit F, Strohmaier J, Teumer A, Treutlein J, Van der Auwera S, van Grootheest G, van Hemert AM, Völzke H, Webb BT, Weissman MM, Wellmann J, Willemsen G, Witt SH, Levinson DF, Lewis CM, Wray NR, Flint J, Sullivan PF, Kendler KS.

Transl Psychiatry. 2017 Mar 28;7(3):e1074. doi: 10.1038/tp.2016.292.


Mathematical Modeling of Streptococcus pneumoniae Colonization, Invasive Infection and Treatment.

Domínguez-Hüttinger E, Boon NJ, Clarke TB, Tanaka RJ.

Front Physiol. 2017 Mar 2;8:115. doi: 10.3389/fphys.2017.00115. eCollection 2017.


Duplication and concerted evolution of MiSp-encoding genes underlie the material properties of minor ampullate silks of cobweb weaving spiders.

Vienneau-Hathaway JM, Brassfield ER, Lane AK, Collin MA, Correa-Garhwal SM, Clarke TH, Schwager EE, Garb JE, Hayashi CY, Ayoub NA.

BMC Evol Biol. 2017 Mar 14;17(1):78. doi: 10.1186/s12862-017-0927-x.


PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination.

Clarke TL, Sanchez-Bailon MP, Chiang K, Reynolds JJ, Herrero-Ruiz J, Bandeiras TM, Matias PM, Maslen SL, Skehel JM, Stewart GS, Davies CC.

Mol Cell. 2017 Mar 2;65(5):900-916.e7. doi: 10.1016/j.molcel.2017.01.019. Epub 2017 Feb 23.


The metabolic impact of extracellular nitrite on aerobic metabolism of Paracoccus denitrificans.

Hartop KR, Sullivan MJ, Giannopoulos G, Gates AJ, Bond PL, Yuan Z, Clarke TA, Rowley G, Richardson DJ.

Water Res. 2017 Apr 15;113:207-214. doi: 10.1016/j.watres.2017.02.011. Epub 2017 Feb 7.


Genome-wide Regional Heritability Mapping Identifies a Locus Within the TOX2 Gene Associated With Major Depressive Disorder.

Zeng Y, Navarro P, Shirali M, Howard DM, Adams MJ, Hall LS, Clarke TK, Thomson PA, Smith BH, Murray A, Padmanabhan S, Hayward C, Boutin T, MacIntyre DJ, Lewis CM, Wray NR, Mehta D, Penninx BWJH, Milaneschi Y, Baune BT, Air T, Hottenga JJ, Mbarek H, Castelao E, Pistis G, Schulze TG, Streit F, Forstner AJ, Byrne EM, Martin NG, Breen G, Müller-Myhsok B, Lucae S, Kloiber S, Domenici E; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Deary IJ, Porteous DJ, Haley CS, McIntosh AM.

Biol Psychiatry. 2017 Sep 1;82(5):312-321. doi: 10.1016/j.biopsych.2016.12.012. Epub 2016 Dec 16.


Rapid Decrease in Populations of Wild Ring-Tailed Lemurs (Lemur catta) in Madagascar.

LaFleur M, Clarke TA, Reuter K, Schaeffer T.

Folia Primatol (Basel). 2016;87(5):320-330. doi: 10.1159/000455121. Epub 2017 Jan 13.


Endangered species: Illegal lemur trade grows in Madagascar.

Reuter KE, LaFleur M, Clarke TA.

Nature. 2017 Jan 11;541(7636):157. doi: 10.1038/541157d. No abstract available.


An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype.

Direk N, Williams S, Smith JA, Ripke S, Air T, Amare AT, Amin N, Baune BT, Bennett DA, Blackwood DHR, Boomsma D, Breen G, Buttenschøn HN, Byrne EM, Børglum AD, Castelao E, Cichon S, Clarke TK, Cornelis MC, Dannlowski U, De Jager PL, Demirkan A, Domenici E, van Duijn CM, Dunn EC, Eriksson JG, Esko T, Faul JD, Ferrucci L, Fornage M, de Geus E, Gill M, Gordon SD, Grabe HJ, van Grootheest G, Hamilton SP, Hartman CA, Heath AC, Hek K, Hofman A, Homuth G, Horn C, Jan Hottenga J, Kardia SLR, Kloiber S, Koenen K, Kutalik Z, Ladwig KH, Lahti J, Levinson DF, Lewis CM, Lewis G, Li QS, Llewellyn DJ, Lucae S, Lunetta KL, MacIntyre DJ, Madden P, Martin NG, McIntosh AM, Metspalu A, Milaneschi Y, Montgomery GW, Mors O, Mosley TH Jr, Murabito JM, Müller-Myhsok B, Nöthen MM, Nyholt DR, O'Donovan MC, Penninx BW, Pergadia ML, Perlis R, Potash JB, Preisig M, Purcell SM, Quiroz JA, Räikkönen K, Rice JP, Rietschel M, Rivera M, Schulze TG, Shi J, Shyn S, Sinnamon GC, Smit JH, Smoller JW, Snieder H, Tanaka T, Tansey KE, Teumer A, Uher R, Umbricht D, Van der Auwera S, Ware EB, Weir DR, Weissman MM, Willemsen G, Yang J, Zhao W, Tiemeier H, Sullivan PF.

Biol Psychiatry. 2017 Sep 1;82(5):322-329. doi: 10.1016/j.biopsych.2016.11.013. Epub 2016 Dec 8.


OPRD1 Genetic Variation and Human Disease.

Crist RC, Clarke TK.

Handb Exp Pharmacol. 2016 Dec 30. doi: 10.1007/164_2016_112. [Epub ahead of print]


A programme of research to set priorities and reduce uncertainties for the prevention and treatment of skin disease.

Thomas KS, Batchelor JM, Bath-Hextall F, Chalmers JR, Clarke T, Crowe S, Delamere FM, Eleftheriadou V, Evans N, Firkins L, Greenlaw N, Lansbury L, Lawton S, Layfield C, Leonardi-Bee J, Mason J, Mitchell E, Nankervis H, Norrie J, Nunn A, Ormerod AD, Patel R, Perkins W, Ravenscroft JC, Schmitt J, Simpson E, Whitton ME, Williams HC.

Southampton (UK): NIHR Journals Library; 2016 Dec.


KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference.

Schumann G, Liu C, O'Reilly P, Gao H, Song P, Xu B, Ruggeri B, Amin N, Jia T, Preis S, Segura Lepe M, Akira S, Barbieri C, Baumeister S, Cauchi S, Clarke TK, Enroth S, Fischer K, Hällfors J, Harris SE, Hieber S, Hofer E, Hottenga JJ, Johansson Å, Joshi PK, Kaartinen N, Laitinen J, Lemaitre R, Loukola A, Luan J, Lyytikäinen LP, Mangino M, Manichaikul A, Mbarek H, Milaneschi Y, Moayyeri A, Mukamal K, Nelson C, Nettleton J, Partinen E, Rawal R, Robino A, Rose L, Sala C, Satoh T, Schmidt R, Schraut K, Scott R, Smith AV, Starr JM, Teumer A, Trompet S, Uitterlinden AG, Venturini C, Vergnaud AC, Verweij N, Vitart V, Vuckovic D, Wedenoja J, Yengo L, Yu B, Zhang W, Zhao JH, Boomsma DI, Chambers J, Chasman DI, Daniela T, de Geus E, Deary I, Eriksson JG, Esko T, Eulenburg V, Franco OH, Froguel P, Gieger C, Grabe HJ, Gudnason V, Gyllensten U, Harris TB, Hartikainen AL, Heath AC, Hocking L, Hofman A, Huth C, Jarvelin MR, Jukema JW, Kaprio J, Kooner JS, Kutalik Z, Lahti J, Langenberg C, Lehtimäki T, Liu Y, Madden PA, Martin N, Morrison A, Penninx B, Pirastu N, Psaty B, Raitakari O, Ridker P, Rose R, Rotter JI, Samani NJ, Schmidt H, Spector TD, Stott D, Strachan D, Tzoulaki I, van der Harst P, van Duijn CM, Marques-Vidal P, Vollenweider P, Wareham NJ, Whitfield JB, Wilson J, Wolffenbuttel B, Bakalkin G, Evangelou E, Liu Y, Rice KM, Desrivières S, Kliewer SA, Mangelsdorf DJ, Müller CP, Levy D, Elliott P.

Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14372-14377. Epub 2016 Nov 28.


Fragments of Expectorated Clothing From the Battle of Gettysburg.

Clarke T Jr.

Mil Med. 2016 Nov;181(11):1402-1403. No abstract available.


Shared Genetics and Couple-Associated Environment Are Major Contributors to the Risk of Both Clinical and Self-Declared Depression.

Zeng Y, Navarro P, Xia C, Amador C, Fernandez-Pujals AM, Thomson PA, Campbell A, Nagy R, Clarke TK, Hafferty JD, Smith BH, Hocking LJ, Padmanabhan S, Hayward C, MacIntyre DJ, Porteous DJ, Haley CS, McIntosh AM.

EBioMedicine. 2016 Dec;14:161-167. doi: 10.1016/j.ebiom.2016.11.003. Epub 2016 Nov 4.


Dissection of major depressive disorder using polygenic risk scores for schizophrenia in two independent cohorts.

Whalley HC, Adams MJ, Hall LS, Clarke TK, Fernandez-Pujals AM, Gibson J, Wigmore E, Hafferty J, Hagenaars SP, Davies G, Campbell A, Hayward C, Lawrie SM, Porteous DJ, Deary IJ, McIntosh AM.

Transl Psychiatry. 2016 Nov 1;6(11):e938. doi: 10.1038/tp.2016.207.


Staphylococcus aureus inactivates daptomycin by releasing membrane phospholipids.

Pader V, Hakim S, Painter KL, Wigneshweraraj S, Clarke TB, Edwards AM.

Nat Microbiol. 2016 Oct 24;2:16194. doi: 10.1038/nmicrobiol.2016.194.

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