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Items: 1 to 50 of 76

1.

Surface tension-assisted additive manufacturing.

Ragelle H, Tibbitt MW, Wu SY, Castillo MA, Cheng GZ, Gangadharan SP, Anderson DG, Cima MJ, Langer R.

Nat Commun. 2018 Mar 22;9(1):1184. doi: 10.1038/s41467-018-03391-w.

2.

Miniaturized neural system for chronic, local intracerebral drug delivery.

Dagdeviren C, Ramadi KB, Joe P, Spencer K, Schwerdt HN, Shimazu H, Delcasso S, Amemori KI, Nunez-Lopez C, Graybiel AM, Cima MJ, Langer R.

Sci Transl Med. 2018 Jan 24;10(425). pii: eaan2742. doi: 10.1126/scitranslmed.aan2742.

PMID:
29367347
3.

Long-term dopamine neurochemical monitoring in primates.

Schwerdt HN, Shimazu H, Amemori KI, Amemori S, Tierney PL, Gibson DJ, Hong S, Yoshida T, Langer R, Cima MJ, Graybiel AM.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):13260-13265. doi: 10.1073/pnas.1713756114. Epub 2017 Nov 20.

PMID:
29158415
4.

Erratum: Characterization of Mechanically Matched Hydrogel Coatings to Improve the Biocompatibility of Neural Implants.

Spencer KC, Sy JC, Ramadi KB, Graybiel AM, Langer R, Cima MJ.

Sci Rep. 2017 Oct 9;7(1):12812. doi: 10.1038/s41598-017-12312-8.

5.

Expanded Medicaid Provides Access to Substance Use, Mental Health, and Physician Visits to Homeless and Precariously Housed Persons.

Parker RD, Cima MJ, Brown Z, Regier M.

J Community Health. 2018 Apr;43(2):207-211. doi: 10.1007/s10900-017-0405-9.

PMID:
28707181
6.

Characterization of Mechanically Matched Hydrogel Coatings to Improve the Biocompatibility of Neural Implants.

Spencer KC, Sy JC, Ramadi KB, Graybiel AM, Langer R, Cima MJ.

Sci Rep. 2017 May 16;7(1):1952. doi: 10.1038/s41598-017-02107-2. Erratum in: Sci Rep. 2017 Oct 9;7(1):12812.

7.

Ovarian cancer spheroid shrinkage following continuous exposure to cisplatin is a function of spheroid diameter.

Tanenbaum LM, Mantzavinou A, Subramanyam KS, Del Carmen MG, Cima MJ.

Gynecol Oncol. 2017 Jul;146(1):161-169. doi: 10.1016/j.ygyno.2017.04.014. Epub 2017 May 10.

PMID:
28499648
8.

Subcellular probes for neurochemical recording from multiple brain sites.

Schwerdt HN, Kim MJ, Amemori S, Homma D, Yoshida T, Shimazu H, Yerramreddy H, Karasan E, Langer R, Graybiel AM, Cima MJ.

Lab Chip. 2017 Mar 14;17(6):1104-1115. doi: 10.1039/c6lc01398h.

9.

A three dimensional in vitro glial scar model to investigate the local strain effects from micromotion around neural implants.

Spencer KC, Sy JC, Falcón-Banchs R, Cima MJ.

Lab Chip. 2017 Feb 28;17(5):795-804. doi: 10.1039/c6lc01411a.

10.

Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors.

Davidson SM, Jonas O, Keibler MA, Hou HW, Luengo A, Mayers JR, Wyckoff J, Del Rosario AM, Whitman M, Chin CR, Condon KJ, Lammers A, Kellersberger KA, Stall BK, Stephanopoulos G, Bar-Sagi D, Han J, Rabinowitz JD, Cima MJ, Langer R, Vander Heiden MG.

Nat Med. 2017 Feb;23(2):235-241. doi: 10.1038/nm.4256. Epub 2016 Dec 26.

11.

Adherence to HIV Treatment and Care at a Rural Appalachian HIV Clinic.

Parker RD, Mangine CM, Hendricks BM, Cima MJ, Mcie S, Sarwari A.

J Assoc Nurses AIDS Care. 2017 Jan - Feb;28(1):67-74. doi: 10.1016/j.jana.2016.09.002. Epub 2016 Sep 16.

PMID:
27742429
12.

Integrated genetic and pharmacologic interrogation of rare cancers.

Hong AL, Tseng YY, Cowley GS, Jonas O, Cheah JH, Kynnap BD, Doshi MB, Oh C, Meyer SC, Church AJ, Gill S, Bielski CM, Keskula P, Imamovic A, Howell S, Kryukov GV, Clemons PA, Tsherniak A, Vazquez F, Crompton BD, Shamji AF, Rodriguez-Galindo C, Janeway KA, Roberts CW, Stegmaier K, van Hummelen P, Cima MJ, Langer RS, Garraway LA, Schreiber SL, Root DE, Hahn WC, Boehm JS.

Nat Commun. 2016 Jun 22;7:11987. doi: 10.1038/ncomms11987.

13.

Parallel In Vivo Assessment of Drug Phenotypes at Various Time Points during Systemic BRAF Inhibition Reveals Tumor Adaptation and Altered Treatment Vulnerabilities.

Jonas O, Oudin MJ, Kosciuk T, Whitman M, Gertler FB, Cima MJ, Flaherty KT, Langer R.

Clin Cancer Res. 2016 Dec 15;22(24):6031-6038. Epub 2016 Apr 18.

14.

Tumor Cell-Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression.

Oudin MJ, Jonas O, Kosciuk T, Broye LC, Guido BC, Wyckoff J, Riquelme D, Lamar JM, Asokan SB, Whittaker C, Ma D, Langer R, Cima MJ, Wisinski KB, Hynes RO, Lauffenburger DA, Keely PJ, Bear JE, Gertler FB.

Cancer Discov. 2016 May;6(5):516-31. doi: 10.1158/2159-8290.CD-15-1183. Epub 2016 Jan 25.

15.

Sustained, low-dose intraperitoneal cisplatin improves treatment outcome in ovarian cancer mouse models.

Ye H, Tanenbaum LM, Na YJ, Mantzavinou A, Fulci G, Del Carmen MG, Birrer MJ, Cima MJ.

J Control Release. 2015 Dec 28;220(Pt A):358-367. doi: 10.1016/j.jconrel.2015.11.001. Epub 2015 Nov 5.

PMID:
26548976
16.

Depot delivery of dexamethasone and cediranib for the treatment of brain tumor associated edema in an intracranial rat glioma model.

Ong Q, Hochberg FH, Cima MJ.

J Control Release. 2015 Nov 10;217:183-90. doi: 10.1016/j.jconrel.2015.08.028. Epub 2015 Aug 15.

PMID:
26285064
17.

Miniaturized, biopsy-implantable chemical sensor with wireless, magnetic resonance readout.

Vassiliou CC, Liu VH, Cima MJ.

Lab Chip. 2015 Sep 7;15(17):3465-72. doi: 10.1039/c5lc00546a. Epub 2015 Jul 16.

PMID:
26177607
18.

(1)H nuclear magnetic resonance (NMR) as a tool to measure dehydration in mice.

Li M, Vassiliou CC, Colucci LA, Cima MJ.

NMR Biomed. 2015 Aug;28(8):1031-9. doi: 10.1002/nbm.3334. Epub 2015 Jun 30.

PMID:
26123278
19.

If It's Not One Thing, It's Another: An Inverse Relationship of Malignancy and Atherosclerotic Disease.

Li M, Cima MJ, Milner DA Jr.

PLoS One. 2015 May 22;10(5):e0126855. doi: 10.1371/journal.pone.0126855. eCollection 2015.

20.

An implantable microdevice to perform high-throughput in vivo drug sensitivity testing in tumors.

Jonas O, Landry HM, Fuller JE, Santini JT Jr, Baselga J, Tepper RI, Cima MJ, Langer R.

Sci Transl Med. 2015 Apr 22;7(284):284ra57. doi: 10.1126/scitranslmed.3010564.

21.

Next-generation wearable electronics.

Cima MJ.

Nat Biotechnol. 2014 Jul;32(7):642-3. doi: 10.1038/nbt.2952. No abstract available.

PMID:
25004232
22.

Single compartment drug delivery.

Cima MJ, Lee H, Daniel K, Tanenbaum LM, Mantzavinou A, Spencer KC, Ong Q, Sy JC, Santini J Jr, Schoellhammer CM, Blankschtein D, Langer RS.

J Control Release. 2014 Sep 28;190:157-71. doi: 10.1016/j.jconrel.2014.04.049. Epub 2014 May 4. Review.

23.

Solid MRI contrast agents for long-term, quantitative in vivo oxygen sensing.

Liu VH, Vassiliou CC, Imaad SM, Cima MJ.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6588-93. doi: 10.1073/pnas.1400015111. Epub 2014 Apr 21.

24.

Enriched protein screening of human bone marrow mesenchymal stromal cell secretions reveals MFAP5 and PENK as novel IL-10 modulators.

Milwid JM, Elman JS, Li M, Shen K, Manrai A, Gabow A, Yarmush J, Jiao Y, Fletcher A, Lee J, Cima MJ, Yarmush ML, Parekkadan B.

Mol Ther. 2014 May;22(5):999-1007. doi: 10.1038/mt.2014.17. Epub 2014 Feb 5.

25.

Intracranial MEMS based temozolomide delivery in a 9L rat gliosarcoma model.

Masi BC, Tyler BM, Bow H, Wicks RT, Xue Y, Brem H, Langer R, Cima MJ.

Biomaterials. 2012 Aug;33(23):5768-75. doi: 10.1016/j.biomaterials.2012.04.048. Epub 2012 May 14.

26.

First-in-human testing of a wirelessly controlled drug delivery microchip.

Farra R, Sheppard NF Jr, McCabe L, Neer RM, Anderson JM, Santini JT Jr, Cima MJ, Langer R.

Sci Transl Med. 2012 Feb 22;4(122):122ra21. doi: 10.1126/scitranslmed.3003276. Epub 2012 Feb 16.

27.

Implantable magnetic relaxation sensors measure cumulative exposure to cardiac biomarkers.

Ling Y, Pong T, Vassiliou CC, Huang PL, Cima MJ.

Nat Biotechnol. 2011 Mar;29(3):273-7. doi: 10.1038/nbt.1780. Epub 2011 Feb 13.

PMID:
21317907
28.

Intracranial microcapsule drug delivery device for the treatment of an experimental gliosarcoma model.

Scott AW, Tyler BM, Masi BC, Upadhyay UM, Patta YR, Grossman R, Basaldella L, Langer RS, Brem H, Cima MJ.

Biomaterials. 2011 Apr;32(10):2532-9. doi: 10.1016/j.biomaterials.2010.12.020. Epub 2011 Jan 8.

PMID:
21220172
29.

Microsystem technologies for medical applications.

Cima MJ.

Annu Rev Chem Biomol Eng. 2011;2:355-78. doi: 10.1146/annurev-chembioeng-061010-114120. Review.

PMID:
22432623
30.

An intravesical device for the sustained delivery of lidocaine to the bladder.

Lee H, Cima MJ.

J Control Release. 2011 Jan 20;149(2):133-9. doi: 10.1016/j.jconrel.2010.10.016. Epub 2010 Oct 30.

PMID:
20971144
31.

Electro-thermally induced structural failure actuator (ETISFA) for implantable controlled drug delivery devices based on micro-electro-mechanical-systems.

Elman NM, Masi BC, Cima MJ, Langer R.

Lab Chip. 2010 Oct 21;10(20):2796-804. doi: 10.1039/c005135g. Epub 2010 Aug 27.

PMID:
20820485
32.

Scaling of transverse nuclear magnetic relaxation due to magnetic nanoparticle aggregation.

Brown KA, Vassiliou CC, Issadore D, Berezovsky J, Cima MJ, Westervelt RM.

J Magn Magn Mater. 2010 Oct 1;322(20):3122-3126.

33.

Magnetic relaxation-based platform for multiplexed assays.

Ling Y, Vassiliou CC, Cima MJ.

Analyst. 2010 Sep;135(9):2360-4. doi: 10.1039/b926041m. Epub 2010 Jul 13.

PMID:
20625581
34.

Zero-order controlled release of ciprofloxacin-HCl from a reservoir-based, bioresorbable and elastomeric device.

Tobias IS, Lee H, Engelmayr GC Jr, Macaya D, Bettinger CJ, Cima MJ.

J Control Release. 2010 Sep 15;146(3):356-62. doi: 10.1016/j.jconrel.2010.05.036. Epub 2010 Jun 4.

35.

Implantable diagnostic device for cancer monitoring.

Daniel KD, Kim GY, Vassiliou CC, Galindo M, Guimaraes AR, Weissleder R, Charest A, Langer R, Cima MJ.

Biosens Bioelectron. 2009 Jul 15;24(11):3252-7. doi: 10.1016/j.bios.2009.04.010. Epub 2009 Apr 16.

36.

The next generation of drug-delivery microdevices.

Elman NM, Patta Y, Scott AW, Masi B, Ho Duc HL, Cima MJ.

Clin Pharmacol Ther. 2009 May;85(5):544-7. doi: 10.1038/clpt.2009.4. Epub 2009 Feb 25. No abstract available.

PMID:
19242402
37.

An implantable MEMS drug delivery device for rapid delivery in ambulatory emergency care.

Elman NM, Ho Duc HL, Cima MJ.

Biomed Microdevices. 2009 Jun;11(3):625-31. doi: 10.1007/s10544-008-9272-6.

PMID:
19169826
38.

Superparamagnetic iron oxide nanoparticle-aptamer bioconjugates for combined prostate cancer imaging and therapy.

Wang AZ, Bagalkot V, Vasilliou CC, Gu F, Alexis F, Zhang L, Shaikh M, Yuet K, Cima MJ, Langer R, Kantoff PW, Bander NH, Jon S, Farokhzad OC.

ChemMedChem. 2008 Sep;3(9):1311-5. doi: 10.1002/cmdc.200800091. No abstract available.

39.

Magnetic microparticle aggregation for viscosity determination by MR.

Hong R, Cima MJ, Weissleder R, Josephson L.

Magn Reson Med. 2008 Mar;59(3):515-20. doi: 10.1002/mrm.21526.

40.

Multiparameter magnetic relaxation switch assays.

Taktak S, Sosnovik D, Cima MJ, Weissleder R, Josephson L.

Anal Chem. 2007 Dec 1;79(23):8863-9. Epub 2007 Nov 6.

PMID:
17983206
41.

Multi-reservoir device for detecting a soluble cancer biomarker.

Daniel KD, Kim GY, Vassiliou CC, Jalali-Yazdi F, Langer R, Cima MJ.

Lab Chip. 2007 Oct;7(10):1288-93. Epub 2007 Jul 20.

PMID:
17896012
42.

Magnetic relaxation switch detection of human chorionic gonadotrophin.

Kim GY, Josephson L, Langer R, Cima MJ.

Bioconjug Chem. 2007 Nov-Dec;18(6):2024-8. Epub 2007 Sep 25.

PMID:
17892270
43.

Resorbable polymer microchips releasing BCNU inhibit tumor growth in the rat 9L flank model.

Kim GY, Tyler BM, Tupper MM, Karp JM, Langer RS, Brem H, Cima MJ.

J Control Release. 2007 Nov 6;123(2):172-8. Epub 2007 Aug 15.

44.

Did I say that word or did you? Executive dysfunctions in schizophrenic patients affect memory efficiency, but not source attributions.

Peters MJ, Cima MJ, Smeets T, de Vos M, Jelicic M, Merckelbach H.

Cogn Neuropsychiatry. 2007 Sep;12(5):391-411.

PMID:
17690998
45.

Combination of automated high throughput platforms, flow cytometry, and hierarchical clustering to detect cell state.

Kitsos CM, Bhamidipati P, Melnikova I, Cash EP, McNulty C, Furman J, Cima MJ, Levinson D.

Cytometry A. 2007 Jan;71(1):16-27.

46.

Orientation dependence of the isoelectric point of TiO2 (rutile) surfaces.

Bullard JW, Cima MJ.

Langmuir. 2006 Nov 21;22(24):10264-71.

PMID:
17107031
47.

Application of micro- and nano-electromechanical devices to drug delivery.

Staples M, Daniel K, Cima MJ, Langer R.

Pharm Res. 2006 May;23(5):847-63. Epub 2006 May 5. Review.

PMID:
16715375
48.

Spreading and infiltration of inkjet-printed polymer solution droplets on a porous substrate.

Holman RK, Cima MJ, Uhland SA, Sachs E.

J Colloid Interface Sci. 2002 May 15;249(2):432-40.

PMID:
16290618
49.

Surface adsorption effects in the inkjet printing of an aqueous polymer solution on a porous oxide ceramic substrate.

Holman RK, Uhland SA, Cima MJ, Sachs E.

J Colloid Interface Sci. 2002 Mar 15;247(2):266-74.

PMID:
16290465
50.

In vivo delivery of BCNU from a MEMS device to a tumor model.

Li Y, Ho Duc HL, Tyler B, Williams T, Tupper M, Langer R, Brem H, Cima MJ.

J Control Release. 2005 Aug 18;106(1-2):138-45.

PMID:
16167384

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