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Items: 13

1.

A microengineered vascularized bleeding model that integrates the principal components of hemostasis.

Sakurai Y, Hardy ET, Ahn B, Tran R, Fay ME, Ciciliano JC, Mannino RG, Myers DR, Qiu Y, Carden MA, Baldwin WH, Meeks SL, Gilbert GE, Jobe SM, Lam WA.

Nat Commun. 2018 Feb 6;9(1):509. doi: 10.1038/s41467-018-02990-x.

2.

Probing blood cell mechanics of hematologic processes at the single micron level.

Ciciliano JC, Abbaspour R, Woodall J, Wu C, Bakir MS, Lam WA.

Lab Chip. 2017 Nov 7;17(22):3804-3816. doi: 10.1039/c7lc00720e.

PMID:
29052682
3.

Extracellular fluid tonicity impacts sickle red blood cell deformability and adhesion.

Carden MA, Fay ME, Lu X, Mannino RG, Sakurai Y, Ciciliano JC, Hansen CE, Chonat S, Joiner CH, Wood DK, Lam WA.

Blood. 2017 Dec 14;130(24):2654-2663. doi: 10.1182/blood-2017-04-780635. Epub 2017 Oct 4.

PMID:
28978568
4.

Single-platelet nanomechanics measured by high-throughput cytometry.

Myers DR, Qiu Y, Fay ME, Tennenbaum M, Chester D, Cuadrado J, Sakurai Y, Baek J, Tran R, Ciciliano JC, Ahn B, Mannino RG, Bunting ST, Bennett C, Briones M, Fernandez-Nieves A, Smith ML, Brown AC, Sulchek T, Lam WA.

Nat Mater. 2017 Feb;16(2):230-235. doi: 10.1038/nmat4772. Epub 2016 Oct 10.

5.

Platelets and physics: How platelets "feel" and respond to their mechanical microenvironment.

Qiu Y, Ciciliano J, Myers DR, Tran R, Lam WA.

Blood Rev. 2015 Nov;29(6):377-86. doi: 10.1016/j.blre.2015.05.002. Epub 2015 May 8. Review.

PMID:
26005062
6.

Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach.

Ciciliano JC, Sakurai Y, Myers DR, Fay ME, Hechler B, Meeks S, Li R, Dixon JB, Lyon LA, Gachet C, Lam WA.

Blood. 2015 Aug 6;126(6):817-24. doi: 10.1182/blood-2015-02-628594. Epub 2015 Apr 30.

7.

Single-cell RNA sequencing identifies extracellular matrix gene expression by pancreatic circulating tumor cells.

Ting DT, Wittner BS, Ligorio M, Vincent Jordan N, Shah AM, Miyamoto DT, Aceto N, Bersani F, Brannigan BW, Xega K, Ciciliano JC, Zhu H, MacKenzie OC, Trautwein J, Arora KS, Shahid M, Ellis HL, Qu N, Bardeesy N, Rivera MN, Deshpande V, Ferrone CR, Kapur R, Ramaswamy S, Shioda T, Toner M, Maheswaran S, Haber DA.

Cell Rep. 2014 Sep 25;8(6):1905-1918. doi: 10.1016/j.celrep.2014.08.029. Epub 2014 Sep 18.

8.

The platelet and the biophysical microenvironment: lessons from cellular mechanics.

Ciciliano JC, Tran R, Sakurai Y, Lam WA.

Thromb Res. 2014 Apr;133(4):532-7. doi: 10.1016/j.thromres.2013.12.037. Epub 2014 Jan 4. Review.

9.

Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells.

Ozkumur E, Shah AM, Ciciliano JC, Emmink BL, Miyamoto DT, Brachtel E, Yu M, Chen PI, Morgan B, Trautwein J, Kimura A, Sengupta S, Stott SL, Karabacak NM, Barber TA, Walsh JR, Smith K, Spuhler PS, Sullivan JP, Lee RJ, Ting DT, Luo X, Shaw AT, Bardia A, Sequist LV, Louis DN, Maheswaran S, Kapur R, Haber DA, Toner M.

Sci Transl Med. 2013 Apr 3;5(179):179ra47. doi: 10.1126/scitranslmed.3005616.

10.

Biomechanics of haemostasis and thrombosis in health and disease: from the macro- to molecular scale.

Tran R, Myers DR, Ciciliano J, Trybus Hardy EL, Sakurai Y, Ahn B, Qiu Y, Mannino RG, Fay ME, Lam WA.

J Cell Mol Med. 2013 May;17(5):579-96. doi: 10.1111/jcmm.12041. Epub 2013 Mar 14. Review.

11.

Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition.

Yu M, Bardia A, Wittner BS, Stott SL, Smas ME, Ting DT, Isakoff SJ, Ciciliano JC, Wells MN, Shah AM, Concannon KF, Donaldson MC, Sequist LV, Brachtel E, Sgroi D, Baselga J, Ramaswamy S, Toner M, Haber DA, Maheswaran S.

Science. 2013 Feb 1;339(6119):580-4. doi: 10.1126/science.1228522.

12.

RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis.

Yu M, Ting DT, Stott SL, Wittner BS, Ozsolak F, Paul S, Ciciliano JC, Smas ME, Winokur D, Gilman AJ, Ulman MJ, Xega K, Contino G, Alagesan B, Brannigan BW, Milos PM, Ryan DP, Sequist LV, Bardeesy N, Ramaswamy S, Toner M, Maheswaran S, Haber DA.

Nature. 2012 Jul 26;487(7408):510-3. doi: 10.1038/nature11217. Erratum in: Nature. 2012 Oct 25;490(7421):570.

13.

Biopolymer system for cell recovery from microfluidic cell capture devices.

Shah AM, Yu M, Nakamura Z, Ciciliano J, Ulman M, Kotz K, Stott SL, Maheswaran S, Haber DA, Toner M.

Anal Chem. 2012 Apr 17;84(8):3682-8. doi: 10.1021/ac300190j. Epub 2012 Apr 3.

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