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Items: 1 to 50 of 113

1.

Adolescent and Young Adult Oncology, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.

Coccia PF, Pappo AS, Beaupin L, Borges VF, Borinstein SC, Chugh R, Dinner S, Folbrecht J, Frazier AL, Goldsby R, Gubin A, Hayashi R, Huang MS, Link MP, Livingston JA, Matloub Y, Millard F, Oeffinger KC, Puccetti D, Reed D, Robinson S, Rosenberg AR, Sanft T, Spraker-Perlman HL, von Mehren M, Wechsler DS, Whelan KF, Yeager N, Gurski LA, Shead DA.

J Natl Compr Canc Netw. 2018 Jan;16(1):66-97. doi: 10.6004/jnccn.2018.0001.

PMID:
29295883
2.

Spotlight on olaratumab in the treatment of soft-tissue sarcoma: design, development, and place in therapy.

Davis EJ, Chugh R.

Drug Des Devel Ther. 2017 Dec 13;11:3579-3587. doi: 10.2147/DDDT.S121298. eCollection 2017. Review.

3.

Intrapulmonary Pharmacokinetics of Levonadifloxacin following Oral Administration of Alalevonadifloxacin to Healthy Adult Subjects.

Rodvold KA, Gotfried MH, Chugh R, Gupta M, Yeole R, Patel A, Bhatia A.

Antimicrob Agents Chemother. 2018 Feb 23;62(3). pii: e02297-17. doi: 10.1128/AAC.02297-17. Print 2018 Mar.

PMID:
29263070
4.

Rapid, ultra low coverage copy number profiling of cell-free DNA as a precision oncology screening strategy.

Hovelson DH, Liu CJ, Wang Y, Kang Q, Henderson J, Gursky A, Brockman S, Ramnath N, Krauss JC, Talpaz M, Kandarpa M, Chugh R, Tuck M, Herman K, Grasso CS, Quist MJ, Feng FY, Haakenson C, Langmore J, Kamberov E, Tesmer T, Husain H, Lonigro RJ, Robinson D, Smith DC, Alva AS, Hussain MH, Chinnaiyan AM, Tewari M, Mills RE, Morgan TM, Tomlins SA.

Oncotarget. 2017 Sep 22;8(52):89848-89866. doi: 10.18632/oncotarget.21163. eCollection 2017 Oct 27.

5.

A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors.

Jimeno A, Gordon M, Chugh R, Messersmith W, Mendelson D, Dupont J, Stagg R, Kapoun AM, Xu L, Uttamsingh S, Brachmann RK, Smith DC.

Clin Cancer Res. 2017 Dec 15;23(24):7490-7497. doi: 10.1158/1078-0432.CCR-17-2157. Epub 2017 Sep 27.

PMID:
28954784
6.

Integrative clinical genomics of metastatic cancer.

Robinson DR, Wu YM, Lonigro RJ, Vats P, Cobain E, Everett J, Cao X, Rabban E, Kumar-Sinha C, Raymond V, Schuetze S, Alva A, Siddiqui J, Chugh R, Worden F, Zalupski MM, Innis J, Mody RJ, Tomlins SA, Lucas D, Baker LH, Ramnath N, Schott AF, Hayes DF, Vijai J, Offit K, Stoffel EM, Roberts JS, Smith DC, Kunju LP, Talpaz M, Cieślik M, Chinnaiyan AM.

Nature. 2017 Aug 17;548(7667):297-303. doi: 10.1038/nature23306. Epub 2017 Aug 2.

PMID:
28783718
7.

Comparison of Plasma and Intrapulmonary Concentrations of Nafithromycin (WCK 4873) in Healthy Adult Subjects.

Rodvold KA, Gotfried MH, Chugh R, Gupta M, Friedland HD, Bhatia A.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e01096-17. doi: 10.1128/AAC.01096-17. Print 2017 Sep.

8.

A Collaborative Approach to Childhood Obesity Surveillance From a Local Health Department.

Alleman E, Murphy E, Baskerville K, Chugh R.

J Public Health Manag Pract. 2017 Nov/Dec;23(6):e17-e20. doi: 10.1097/PHH.0000000000000615.

PMID:
28628581
9.

Next generation sequencing of extraskeletal myxoid chondrosarcoma.

Davis EJ, Wu YM, Robinson D, Schuetze SM, Baker LH, Athanikar J, Cao X, Kunju LP, Chinnaiyan AM, Chugh R.

Oncotarget. 2017 Mar 28;8(13):21770-21777. doi: 10.18632/oncotarget.15568.

10.

Phase I, Dose-Escalation, Two-Part Trial of the PARP Inhibitor Talazoparib in Patients with Advanced Germline BRCA1/2 Mutations and Selected Sporadic Cancers.

de Bono J, Ramanathan RK, Mina L, Chugh R, Glaspy J, Rafii S, Kaye S, Sachdev J, Heymach J, Smith DC, Henshaw JW, Herriott A, Patterson M, Curtin NJ, Byers LA, Wainberg ZA.

Cancer Discov. 2017 Jun;7(6):620-629. doi: 10.1158/2159-8290.CD-16-1250. Epub 2017 Feb 27.

11.

Minnelide Inhibits Androgen Dependent, Castration Resistant Prostate Cancer Growth by Decreasing Expression of Androgen Receptor Full Length and Splice Variants.

Isharwal S, Modi S, Arora N, Uhlrich C 3rd, Giri B, Barlass U, Soubra A, Chugh R, Dehm SM, Dudeja V, Saluja A, Banerjee S, Konety B.

Prostate. 2017 May;77(6):584-596. doi: 10.1002/pros.23298. Epub 2017 Feb 1.

PMID:
28144973
12.

An optimization protocol for Swiss 3T3 feeder cell growth-arrest by Mitomycin C dose-to-volume derivation strategy.

Chugh RM, Chaturvedi M, Yerneni LK.

Cytotechnology. 2017 Apr;69(2):391-404. doi: 10.1007/s10616-017-0064-9. Epub 2017 Jan 21.

13.

A Phase I Study of the Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib (LEE011) in Patients with Advanced Solid Tumors and Lymphomas.

Infante JR, Cassier PA, Gerecitano JF, Witteveen PO, Chugh R, Ribrag V, Chakraborty A, Matano A, Dobson JR, Crystal AS, Parasuraman S, Shapiro GI.

Clin Cancer Res. 2016 Dec 1;22(23):5696-5705. Epub 2016 Aug 19.

14.

Phase 2 study of dasatinib in patients with alveolar soft part sarcoma, chondrosarcoma, chordoma, epithelioid sarcoma, or solitary fibrous tumor.

Schuetze SM, Bolejack V, Choy E, Ganjoo KN, Staddon AP, Chow WA, Tawbi HA, Samuels BL, Patel SR, von Mehren M, D'Amato G, Leu KM, Loeb DM, Forscher CA, Milhem MM, Rushing DA, Lucas DR, Chugh R, Reinke DK, Baker LH.

Cancer. 2017 Jan 1;123(1):90-97. doi: 10.1002/cncr.30379. Epub 2016 Oct 3.

15.

Renal Papillary Necrosis Caused by Protein C Deficiency Leading to Recurrent Hydronephrosis.

Chugh RK, Olorunnisomo V, Fowle EJ, Modica I, Meisels I, Gupta M.

J Endourol Case Rep. 2016 Feb 1;2(1):36-7. doi: 10.1089/cren.2016.0018. eCollection 2016.

16.

Assessment of Imaging Modalities and Response Metrics in Ewing Sarcoma: Correlation With Survival.

Koshkin VS, Bolejack V, Schwartz LH, Wahl RL, Chugh R, Reinke DK, Zhao B, O JH, Patel SR, Schuetze SM, Baker LH.

J Clin Oncol. 2016 Aug 29. pii: JCO681858. [Epub ahead of print]

17.

SPARC expression in patients with high-risk localized soft tissue sarcoma treated on a randomized phase II trial of neo/adjuvant chemotherapy.

Davis EJ, Zhao L, Lucas DR, Schuetze SM, Baker LH, Zalupski MM, Thomas D, Chugh R.

BMC Cancer. 2016 Aug 20;16:663. doi: 10.1186/s12885-016-2694-2.

18.

A bivalent promoter contributes to stress-induced plasticity of CXCR4 in Ewing sarcoma.

Krook MA, Hawkins AG, Patel RM, Lucas DR, Van Noord R, Chugh R, Lawlor ER.

Oncotarget. 2016 Sep 20;7(38):61775-61788. doi: 10.18632/oncotarget.11240.

19.

Activation of Wnt/β-Catenin in Ewing Sarcoma Cells Antagonizes EWS/ETS Function and Promotes Phenotypic Transition to More Metastatic Cell States.

Pedersen EA, Menon R, Bailey KM, Thomas DG, Van Noord RA, Tran J, Wang H, Qu PP, Hoering A, Fearon ER, Chugh R, Lawlor ER.

Cancer Res. 2016 Sep 1;76(17):5040-53. doi: 10.1158/0008-5472.CAN-15-3422. Epub 2016 Jun 30.

20.

Exposure cell number during feeder cell growth-arrest by Mitomycin C is a critical pharmacological aspect in stem cell culture system.

Chugh RM, Chaturvedi M, Yerneni LK.

J Pharmacol Toxicol Methods. 2016 Jul-Aug;80:68-74. doi: 10.1016/j.vascn.2016.05.006. Epub 2016 May 10.

PMID:
27178105
21.

Stepwise development of a cancer care delivery research study to evaluate the prevalence of virus infections in cancer patients.

Unger JM, Hershman DL, Arnold KB, Loomba R, Chugh R, Hwang JP, O'Rourke MA, Bhadkamkar NA, Wang LX, Siegel AB, Cooley TP, Berenberg JL, Bridges BB, Ramsey SD.

Future Oncol. 2016 May;12(10):1219-31. doi: 10.2217/fon-2015-0076. Epub 2016 Mar 8.

22.

Associations of vitamin D status, bone health and anthropometry, with gross motor development and performance of school-aged Indian children who were born at term with low birth weight.

Filteau S, Rehman AM, Yousafzai A, Chugh R, Kaur M, Sachdev HP, Trilok-Kumar G.

BMJ Open. 2016 Jan 8;6(1):e009268. doi: 10.1136/bmjopen-2015-009268.

23.

SARC009: Phase 2 study of dasatinib in patients with previously treated, high-grade, advanced sarcoma.

Schuetze SM, Wathen JK, Lucas DR, Choy E, Samuels BL, Staddon AP, Ganjoo KN, von Mehren M, Chow WA, Loeb DM, Tawbi HA, Rushing DA, Patel SR, Thomas DG, Chugh R, Reinke DK, Baker LH.

Cancer. 2016 Mar 15;122(6):868-74. doi: 10.1002/cncr.29858. Epub 2015 Dec 28.

24.

A Novel Immunocompetent Mouse Model of Pancreatic Cancer with Robust Stroma: a Valuable Tool for Preclinical Evaluation of New Therapies.

Majumder K, Arora N, Modi S, Chugh R, Nomura A, Giri B, Dawra R, Ramakrishnan S, Banerjee S, Saluja A, Dudeja V.

J Gastrointest Surg. 2016 Jan;20(1):53-65; discussion 65. doi: 10.1007/s11605-015-2985-y. Epub 2015 Nov 18.

25.

Poor Vitamin D Status in Healthy Populations in India: A Review of Current Evidence.

Trilok Kumar G, Chugh R, Eggersdorfer M.

Int J Vitam Nutr Res. 2015;85(3-4):185-201. doi: 10.1024/0300-9831/a000228. Epub 2015 Nov 17. Review.

26.

Meningococcal disease among men who have sex with men - United States, January 2012-June 2015.

Kamiya H, MacNeil J, Blain A, Patel M, Martin S, Weiss D, Ngai S, Ezeoke I, Mascola L, Civen R, Ngo V, Black S, Kemble S, Chugh R, Murphy E, Petit C, Harriman K, Winter K, Beron A, Clegg W, Conover C, Misegades L.

MMWR Morb Mortal Wkly Rep. 2015 Nov 13;64(44):1256-7. doi: 10.15585/mmwr.mm6444a6.

27.

An evaluation of the choice of feeder cell growth arrest for the production of cultured epidermis.

Chugh RM, Chaturvedi M, Yerneni LK.

Burns. 2015 Dec;41(8):1788-1795. doi: 10.1016/j.burns.2015.08.011. Epub 2015 Sep 29.

PMID:
26392024
28.

Aldoxorubicin in Sarcoma: Teaching an Old Drug New Tricks.

Chugh R, Schuetze SM.

JAMA Oncol. 2015 Dec;1(9):1280-1. doi: 10.1001/jamaoncol.2015.3221. No abstract available.

PMID:
26379207
29.

The use of exome capture RNA-seq for highly degraded RNA with application to clinical cancer sequencing.

Cieslik M, Chugh R, Wu YM, Wu M, Brennan C, Lonigro R, Su F, Wang R, Siddiqui J, Mehra R, Cao X, Lucas D, Chinnaiyan AM, Robinson D.

Genome Res. 2015 Sep;25(9):1372-81. doi: 10.1101/gr.189621.115. Epub 2015 Aug 7.

30.

Effects of vitamin D supplementation in infancy on growth, bone parameters, body composition and gross motor development at age 3-6 years: follow-up of a randomized controlled trial.

Trilok-Kumar G, Kaur M, Rehman AM, Arora H, Rajput MM, Chugh R, Kurpad A, Sachdev HS, Filteau S.

Int J Epidemiol. 2015 Jun;44(3):894-905. doi: 10.1093/ije/dyv116. Epub 2015 Jun 30.

PMID:
26130740
31.

Lack of Transmission among Close Contacts of Patient with Case of Middle East Respiratory Syndrome Imported into the United States, 2014.

Breakwell L, Pringle K, Chea N, Allen D, Allen S, Richards S, Pantones P, Sandoval M, Liu L, Vernon M, Conover C, Chugh R, DeMaria A, Burns R, Smole S, Gerber SI, Cohen NJ, Kuhar D, Haynes LM, Schneider E, Kumar A, Kapoor M, Madrigal M, Swerdlow DL, Feikin DR.

Emerg Infect Dis. 2015 Jul;21(7):1128-34. doi: 10.3201/eid2107.150054.

32.

A randomised, open-label, phase II study of neo/adjuvant doxorubicin and ifosfamide versus gemcitabine and docetaxel in patients with localised, high-risk, soft tissue sarcoma.

Davis EJ, Chugh R, Zhao L, Lucas DR, Biermann JS, Zalupski MM, Feng M, Wong SL, Jacobson J, Zyczynski L, Reinke D, Metko G, Baker LH, Schuetze SM.

Eur J Cancer. 2015 Sep;51(13):1794-802. doi: 10.1016/j.ejca.2015.05.010. Epub 2015 Jun 9.

PMID:
26066736
33.

Triptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F.

Oliveira A, Beyer G, Chugh R, Skube SJ, Majumder K, Banerjee S, Sangwan V, Li L, Dawra R, Subramanian S, Saluja A, Dudeja V.

Lab Invest. 2015 Jun;95(6):648-659. doi: 10.1038/labinvest.2015.46. Epub 2015 Apr 20.

34.

Cancer targeted magic bullets for effective treatment of cancer.

Aneja P, Rahman M, Beg S, Aneja S, Dhingra V, Chugh R.

Recent Pat Antiinfect Drug Discov. 2014;9(2):121-35. Review.

PMID:
25876849
35.

Primary and liver metastasis-derived cell lines from KrasG12D; Trp53R172H; Pdx-1 Cre animals undergo apoptosis in response to triptolide.

Sangwan V, Banerjee S, Jensen KM, Chen Z, Chugh R, Dudeja V, Vickers SM, Saluja AK.

Pancreas. 2015 May;44(4):583-9. doi: 10.1097/MPA.0000000000000317.

36.

Doxorubicin plus the IGF-1R antibody cixutumumab in soft tissue sarcoma: a phase I study using the TITE-CRM model.

Chugh R, Griffith KA, Davis EJ, Thomas DG, Zavala JD, Metko G, Brockstein B, Undevia SD, Stadler WM, Schuetze SM.

Ann Oncol. 2015 Jul;26(7):1459-64. doi: 10.1093/annonc/mdv171. Epub 2015 Apr 9.

37.

CD133 initiates tumors, induces epithelial-mesenchymal transition and increases metastasis in pancreatic cancer.

Nomura A, Banerjee S, Chugh R, Dudeja V, Yamamoto M, Vickers SM, Saluja AK.

Oncotarget. 2015 Apr 10;6(10):8313-22.

38.

Occurrence and control of sporadic proliferation in growth arrested Swiss 3T3 feeder cells.

Chugh RM, Chaturvedi M, Yerneni LK.

PLoS One. 2015 Mar 23;10(3):e0122056. doi: 10.1371/journal.pone.0122056. eCollection 2015.

39.

The multidisciplinary management of bone and soft tissue sarcoma: an essential organizational framework.

Siegel GW, Biermann JS, Chugh R, Jacobson JA, Lucas D, Feng M, Chang AC, Smith SR, Wong SL, Hasen J.

J Multidiscip Healthc. 2015 Feb 19;8:109-15. doi: 10.2147/JMDH.S49805. eCollection 2015. Review.

40.

Safety, pharmacokinetics, and pharmacodynamic properties of oral DEBIO1143 (AT-406) in patients with advanced cancer: results of a first-in-man study.

Hurwitz HI, Smith DC, Pitot HC, Brill JM, Chugh R, Rouits E, Rubin J, Strickler J, Vuagniaux G, Sorensen JM, Zanna C.

Cancer Chemother Pharmacol. 2015 Apr;75(4):851-9. doi: 10.1007/s00280-015-2709-8. Epub 2015 Feb 27.

41.

Diffuse hypopigmentation followed by hyperpigmentation in an african american woman with hemangiopericytoma treated with dasatinib.

Boudadi K, Chugh R.

J Clin Diagn Res. 2014 Nov;8(11):QD01-2. doi: 10.7860/JCDR/2014/8055.5160. Epub 2014 Nov 20.

42.

Elevated circulating levels of the pro-inflammatory cytokine macrophage migration inhibitory factor in individuals with acute spinal cord injury.

Bank M, Stein A, Sison C, Glazer A, Jassal N, McCarthy D, Shatzer M, Hahn B, Chugh R, Davies P, Bloom O.

Arch Phys Med Rehabil. 2015 Apr;96(4):633-44. doi: 10.1016/j.apmr.2014.10.021. Epub 2014 Nov 15.

PMID:
25461821
43.

A phase I dose escalation and expansion study of the anticancer stem cell agent demcizumab (anti-DLL4) in patients with previously treated solid tumors.

Smith DC, Eisenberg PD, Manikhas G, Chugh R, Gubens MA, Stagg RJ, Kapoun AM, Xu L, Dupont J, Sikic B.

Clin Cancer Res. 2014 Dec 15;20(24):6295-303. doi: 10.1158/1078-0432.CCR-14-1373. Epub 2014 Oct 16.

44.

Sorafenib and triptolide as combination therapy for hepatocellular carcinoma.

Alsaied OA, Sangwan V, Banerjee S, Krosch TC, Chugh R, Saluja A, Vickers SM, Jensen EH.

Surgery. 2014 Aug;156(2):270-9. doi: 10.1016/j.surg.2014.04.055. Epub 2014 Jun 19.

PMID:
24953273
45.

Echocardiography for patent ductus arteriosus including closure in adults.

Chugh R, Salem MM.

Echocardiography. 2015 Jan;32 Suppl 2:S125-39. doi: 10.1111/echo.12457. Epub 2014 May 29. Review.

PMID:
24888537
46.

A phase 2 trial of R1507, a monoclonal antibody to the insulin-like growth factor-1 receptor (IGF-1R), in patients with recurrent or refractory rhabdomyosarcoma, osteosarcoma, synovial sarcoma, and other soft tissue sarcomas: results of a Sarcoma Alliance for Research Through Collaboration study.

Pappo AS, Vassal G, Crowley JJ, Bolejack V, Hogendoorn PC, Chugh R, Ladanyi M, Grippo JF, Dall G, Staddon AP, Chawla SP, Maki RG, Araujo DM, Geoerger B, Ganjoo K, Marina N, Blay JY, Schuetze SM, Chow WA, Helman LJ.

Cancer. 2014 Aug 15;120(16):2448-56. doi: 10.1002/cncr.28728. Epub 2014 May 2.

47.

Triptolide activates unfolded protein response leading to chronic ER stress in pancreatic cancer cells.

Mujumdar N, Banerjee S, Chen Z, Sangwan V, Chugh R, Dudeja V, Yamamoto M, Vickers SM, Saluja AK.

Am J Physiol Gastrointest Liver Physiol. 2014 Jun 1;306(11):G1011-20. doi: 10.1152/ajpgi.00466.2013. Epub 2014 Apr 3.

48.

Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the death receptor pathway.

Chen Z, Sangwan V, Banerjee S, Chugh R, Dudeja V, Vickers SM, Saluja AK.

Cancer Lett. 2014 Jun 28;348(1-2):156-66. doi: 10.1016/j.canlet.2014.03.016. Epub 2014 Mar 21.

49.

Stress-induced CXCR4 promotes migration and invasion of ewing sarcoma.

Krook MA, Nicholls LA, Scannell CA, Chugh R, Thomas DG, Lawlor ER.

Mol Cancer Res. 2014 Jun;12(6):953-64. doi: 10.1158/1541-7786.MCR-13-0668. Epub 2014 Mar 20.

50.

CD133+ tumor initiating cells in a syngenic murine model of pancreatic cancer respond to Minnelide.

Banerjee S, Nomura A, Sangwan V, Chugh R, Dudeja V, Vickers SM, Saluja A.

Clin Cancer Res. 2014 May 1;20(9):2388-99. doi: 10.1158/1078-0432.CCR-13-2947. Epub 2014 Mar 14.

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