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Items: 1 to 50 of 54

1.

NK cells mediate synergistic antitumor effects of combined inhibition of HDAC6 and BET in a SCLC preclinical model.

Liu Y, Li Y, Liu S, Adeegbe DO, Christensen CL, Quinn MM, Dries R, Han S, Buczkowski K, Wang X, Chen T, Gao P, Zhang H, Li F, Hammerman PS, Bradner JE, Quayle SN, Wong KK.

Cancer Res. 2018 May 14. pii: canres.0161.2018. doi: 10.1158/0008-5472.CAN-18-0161. [Epub ahead of print]

PMID:
29760044
2.

Genomic and Functional Fidelity of Small Cell Lung Cancer Patient-Derived Xenografts.

Drapkin BJ, George J, Christensen CL, Mino-Kenudson M, Dries R, Sundaresan T, Phat S, Myers DT, Zhong J, Igo P, Hazar-Rethinam MH, Licausi JA, Gomez-Caraballo M, Kem M, Jani KN, Azimi R, Abedpour N, Menon R, Lakis S, Heist RS, Büttner R, Haas S, Sequist LV, Shaw AT, Wong KK, Hata AN, Toner M, Maheswaran S, Haber DA, Peifer M, Dyson N, Thomas RK, Farago AF.

Cancer Discov. 2018 May;8(5):600-615. doi: 10.1158/2159-8290.CD-17-0935. Epub 2018 Feb 26.

PMID:
29483136
3.

High MITF Expression Is Associated with Super-Enhancers and Suppressed by CDK7 Inhibition in Melanoma.

Eliades P, Abraham BJ, Ji Z, Miller DM, Christensen CL, Kwiatkowski N, Kumar R, Njauw CN, Taylor M, Miao B, Zhang T, Wong KK, Gray NS, Young RA, Tsao H.

J Invest Dermatol. 2018 Feb 8. pii: S0022-202X(18)30106-4. doi: 10.1016/j.jid.2017.09.056. [Epub ahead of print]

PMID:
29408204
4.

Overcoming Resistance to the THZ Series of Covalent Transcriptional CDK Inhibitors.

Gao Y, Zhang T, Terai H, Ficarro SB, Kwiatkowski N, Hao MF, Sharma B, Christensen CL, Chipumuro E, Wong KK, Marto JA, Hammerman PS, Gray NS, George RE.

Cell Chem Biol. 2018 Feb 15;25(2):135-142.e5. doi: 10.1016/j.chembiol.2017.11.007. Epub 2017 Dec 21.

PMID:
29276047
5.

Suppression of Adaptive Responses to Targeted Cancer Therapy by Transcriptional Repression.

Rusan M, Li K, Li Y, Christensen CL, Abraham BJ, Kwiatkowski N, Buczkowski KA, Bockorny B, Chen T, Li S, Rhee K, Zhang H, Chen W, Terai H, Tavares T, Leggett AL, Li T, Wang Y, Zhang T, Kim TJ, Hong SH, Poudel-Neupane N, Silkes M, Mudianto T, Tan L, Shimamura T, Meyerson M, Bass AJ, Watanabe H, Gray NS, Young RA, Wong KK, Hammerman PS.

Cancer Discov. 2018 Jan;8(1):59-73. doi: 10.1158/2159-8290.CD-17-0461. Epub 2017 Oct 20.

PMID:
29054992
6.
7.

Analytical sensitivity and diagnostic performance of serum protein electrophoresis on the HYDRAGEL 30 PROTEIN(E) β1-β2 Sebia Hydrasys system.

Tsui AKY, Thomas D, Hunt A, Estey M, Christensen CL, Higgins T, Sandhu I, Rodriguez-Capote K.

Clin Biochem. 2018 Jan;51:80-84. doi: 10.1016/j.clinbiochem.2017.09.007. Epub 2017 Sep 12.

PMID:
28916438
8.

MUC1-C activates EZH2 expression and function in human cancer cells.

Rajabi H, Hiraki M, Tagde A, Alam M, Bouillez A, Christensen CL, Samur M, Wong KK, Kufe D.

Sci Rep. 2017 Aug 7;7(1):7481. doi: 10.1038/s41598-017-07850-0.

9.

Progranulin as a Novel Factor in Gaucher Disease.

Choy FYM, Christensen CL.

EBioMedicine. 2016 Nov;13:13-14. doi: 10.1016/j.ebiom.2016.11.006. Epub 2016 Nov 5. No abstract available.

10.

Synergy of radiotherapy and PD-1 blockade in Kras-mutant lung cancer.

Herter-Sprie GS, Koyama S, Korideck H, Hai J, Deng J, Li YY, Buczkowski KA, Grant AK, Ullas S, Rhee K, Cavanaugh JD, Neupane NP, Christensen CL, Herter JM, Makrigiorgos GM, Hodi FS, Freeman GJ, Dranoff G, Hammerman PS, Kimmelman AC, Wong KK.

JCI Insight. 2016 Jun 16;1(9):e87415.

11.

Non-human Primate Total-body Irradiation Model with Limited and Full Medical Supportive Care Including Filgrastim for Biodosimetry and Injury Assessment.

Ossetrova NI, Blakely WF, Nagy V, McGann C, Ney PH, Christensen CL, Koch AL, Gulani J, Sigal GB, Glezer EN, Hieber KP.

Radiat Prot Dosimetry. 2016 Dec;172(1-3):174-191. doi: 10.1093/rpd/ncw176. Epub 2016 Jul 29.

PMID:
27473690
12.

Cercopithecine Herpesvirus 9 (Simian Varicella Virus) Infection after Total-Body Irradiation in a Rhesus Macaque (Macaca mulatta).

Gulani J, Koch A, Chappell MG, Christensen CL, Facemire P, Singh VK, Ossetrova NI, Srinivasan V, Holt RK.

Comp Med. 2016 Apr;66(2):150-3.

13.

LIFESTAT - Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction.

Christensen CL, Wulff Helge J, Krasnik A, Kriegbaum M, Rasmussen LJ, Hickson ID, Liisberg KB, Oxlund B, Bruun B, Lau SR, Olsen MN, Andersen JS, Heltberg AS, Kuhlman AB, Morville TH, Dohlmann TL, Larsen S, Dela F.

Scand J Public Health. 2016 Jul;44(5):534-9. doi: 10.1177/1403494816636304. Epub 2016 Mar 3.

PMID:
26939591
14.

Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?

Bunn PA Jr, Minna JD, Augustyn A, Gazdar AF, Ouadah Y, Krasnow MA, Berns A, Brambilla E, Rekhtman N, Massion PP, Niederst M, Peifer M, Yokota J, Govindan R, Poirier JT, Byers LA, Wynes MW, McFadden DG, MacPherson D, Hann CL, Farago AF, Dive C, Teicher BA, Peacock CD, Johnson JE, Cobb MH, Wendel HG, Spigel D, Sage J, Yang P, Pietanza MC, Krug LM, Heymach J, Ujhazy P, Zhou C, Goto K, Dowlati A, Christensen CL, Park K, Einhorn LH, Edelman MJ, Giaccone G, Gerber DE, Salgia R, Owonikoko T, Malik S, Karachaliou N, Gandara DR, Slotman BJ, Blackhall F, Goss G, Thomas R, Rudin CM, Hirsch FR.

J Thorac Oncol. 2016 Apr;11(4):453-74. doi: 10.1016/j.jtho.2016.01.012. Epub 2016 Jan 30. Review. No abstract available.

15.

Hemorrhage Exacerbates Radiation Effects on Survival, Leukocytopenia, Thrombopenia, Erythropenia, Bone Marrow Cell Depletion and Hematopoiesis, and Inflammation-Associated microRNAs Expression in Kidney.

Kiang JG, Smith JT, Anderson MN, Swift JM, Christensen CL, Gupta P, Balakathiresan N, Maheshwari RK.

PLoS One. 2015 Sep 30;10(9):e0139271. doi: 10.1371/journal.pone.0139271. eCollection 2015.

16.

A novel double heterozygous Hb Fontainebleau/HbD Punjab hemoglobinopathy.

Rodríguez-Capote K, Estey MP, Barakauskas V, Bordeleau P, Christensen CL, Zuberbuhler P, Higgins TN.

Clin Biochem. 2015 Sep;48(13-14):904-7. doi: 10.1016/j.clinbiochem.2015.05.020. Epub 2015 May 31.

PMID:
26036869
17.

Laparoscopic colpotomy using monopolar electrocautery: does power really matter?

Iwanoff CJ, Barbier HM, Massengill JC, Lombardini ED, Christensen CL, Buller JL, Gruber DD.

Female Pelvic Med Reconstr Surg. 2015 May-Jun;21(3):141-5. doi: 10.1097/SPV.0000000000000146.

PMID:
25521469
18.

Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models.

Herter-Sprie GS, Korideck H, Christensen CL, Herter JM, Rhee K, Berbeco RI, Bennett DG, Akbay EA, Kozono D, Mak RH, Mike Makrigiorgos G, Kimmelman AC, Wong KK.

Nat Commun. 2014 Dec 18;5:5870. doi: 10.1038/ncomms6870.

19.

Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor.

Christensen CL, Kwiatkowski N, Abraham BJ, Carretero J, Al-Shahrour F, Zhang T, Chipumuro E, Herter-Sprie GS, Akbay EA, Altabef A, Zhang J, Shimamura T, Capelletti M, Reibel JB, Cavanaugh JD, Gao P, Liu Y, Michaelsen SR, Poulsen HS, Aref AR, Barbie DA, Bradner JE, George RE, Gray NS, Young RA, Wong KK.

Cancer Cell. 2014 Dec 8;26(6):909-922. doi: 10.1016/j.ccell.2014.10.019. Erratum in: Cancer Cell. 2015 Jan 12;27(1):149.

20.

CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer.

Chipumuro E, Marco E, Christensen CL, Kwiatkowski N, Zhang T, Hatheway CM, Abraham BJ, Sharma B, Yeung C, Altabef A, Perez-Atayde A, Wong KK, Yuan GC, Gray NS, Young RA, George RE.

Cell. 2014 Nov 20;159(5):1126-1139. doi: 10.1016/j.cell.2014.10.024. Epub 2014 Nov 6.

21.

Managing an outpatient parenteral antibiotic therapy team: challenges and solutions.

Halilovic J, Christensen CL, Nguyen HH.

Ther Clin Risk Manag. 2014 Jun 18;10:459-65. doi: 10.2147/TCRM.S48906. eCollection 2014. Review.

22.

D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice.

Akbay EA, Moslehi J, Christensen CL, Saha S, Tchaicha JH, Ramkissoon SH, Stewart KM, Carretero J, Kikuchi E, Zhang H, Cohoon TJ, Murray S, Liu W, Uno K, Fisch S, Jones K, Gurumurthy S, Gliser C, Choe S, Keenan M, Son J, Stanley I, Losman JA, Padera R, Bronson RT, Asara JM, Abdel-Wahab O, Amrein PC, Fathi AT, Danial NN, Kimmelman AC, Kung AL, Ligon KL, Yen KE, Kaelin WG Jr, Bardeesy N, Wong KK.

Genes Dev. 2014 Mar 1;28(5):479-90. doi: 10.1101/gad.231233.113.

23.

Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors.

Akbay EA, Koyama S, Carretero J, Altabef A, Tchaicha JH, Christensen CL, Mikse OR, Cherniack AD, Beauchamp EM, Pugh TJ, Wilkerson MD, Fecci PE, Butaney M, Reibel JB, Soucheray M, Cohoon TJ, Janne PA, Meyerson M, Hayes DN, Shapiro GI, Shimamura T, Sholl LM, Rodig SJ, Freeman GJ, Hammerman PS, Dranoff G, Wong KK.

Cancer Discov. 2013 Dec;3(12):1355-63. doi: 10.1158/2159-8290.CD-13-0310. Epub 2013 Sep 27.

24.

Insertion of a nuclear factor kappa B DNA nuclear-targeting sequence potentiates suicide gene therapy efficacy in lung cancer cell lines.

Cramer F, Christensen CL, Poulsen TT, Badding MA, Dean DA, Poulsen HS.

Cancer Gene Ther. 2012 Oct;19(10):675-83. doi: 10.1038/cgt.2012.54. Epub 2012 Aug 17.

PMID:
22898898
25.

Single agent- and combination treatment with two targeted suicide gene therapy systems is effective in chemoresistant small cell lung cancer cells.

Michaelsen SR, Christensen CL, Sehested M, Cramer F, Poulsen TT, Patterson AV, Poulsen HS.

J Gene Med. 2012 Jul;14(7):445-58. doi: 10.1002/jgm.2630.

PMID:
22576955
26.

Homozygous bisalbuminemia or homozygous mutant albumin?

Kulkarni K, Rowe P, Christensen CL, Higgins T.

Clin Biochem. 2012 Jan;45(1-2):181-2. doi: 10.1016/j.clinbiochem.2011.10.005. Epub 2011 Oct 25.

PMID:
22040810
27.

Impact of a multidisciplinary team review of potential outpatient parenteral antimicrobial therapy prior to discharge from an academic medical center.

Heintz BH, Halilovic J, Christensen CL.

Ann Pharmacother. 2011 Nov;45(11):1329-37. doi: 10.1345/aph.1Q240. Epub 2011 Oct 11.

PMID:
21990938
28.

A simple protocol for preparation of a liposomal vesicle with encapsulated plasmid DNA that mediate high accumulation and reporter gene activity in tumor tissue.

Gjetting T, Andresen TL, Christensen CL, Cramer F, Poulsen TT, Poulsen HS.

Results Pharma Sci. 2011 Sep 3;1(1):49-56. doi: 10.1016/j.rinphs.2011.08.001. eCollection 2011 May.

29.

PRIMA-1Met/APR-246 induces apoptosis and tumor growth delay in small cell lung cancer expressing mutant p53.

Zandi R, Selivanova G, Christensen CL, Gerds TA, Willumsen BM, Poulsen HS.

Clin Cancer Res. 2011 May 1;17(9):2830-41. doi: 10.1158/1078-0432.CCR-10-3168. Epub 2011 Mar 17.

30.

Vancomycin-resistant enterococcal urinary tract infections.

Heintz BH, Halilovic J, Christensen CL.

Pharmacotherapy. 2010 Nov;30(11):1136-49. doi: 10.1592/phco.30.11.1136. Review.

PMID:
20973687
31.

In vitro and in vivo effects of polyethylene glycol (PEG)-modified lipid in DOTAP/cholesterol-mediated gene transfection.

Gjetting T, Arildsen NS, Christensen CL, Poulsen TT, Roth JA, Handlos VN, Poulsen HS.

Int J Nanomedicine. 2010 Aug 9;5:371-83.

32.

Targeted cytosine deaminase-uracil phosphoribosyl transferase suicide gene therapy induces small cell lung cancer-specific cytotoxicity and tumor growth delay.

Christensen CL, Gjetting T, Poulsen TT, Cramer F, Roth JA, Poulsen HS.

Clin Cancer Res. 2010 Apr 15;16(8):2308-19. doi: 10.1158/1078-0432.CCR-09-3057. Epub 2010 Apr 6.

33.

Effect of teriparatide [rhPTH(1,34)] and calcitonin on intertransverse process fusion in a rabbit model.

Lehman RA Jr, Dmitriev AE, Cardoso MJ, Helgeson MD, Christensen CL, Raymond JW, Eckel TT, Riew KD.

Spine (Phila Pa 1976). 2010 Jan 15;35(2):146-52. doi: 10.1097/BRS.0b013e3181b71a96.

PMID:
20081509
34.

Effects of a multilevel dietary intervention in religious organizations.

Bowen DJ, Beresford SA, Christensen CL, Kuniyuki AA, McLerran D, Feng Z, Hart A Jr, Tinker L, Campbell M, Satia J.

Am J Health Promot. 2009 Sep-Oct;24(1):15-22. doi: 10.4278/ajhp.07030823.

PMID:
19750958
35.

[Self-harm in children and adolescents].

Søgaard LE, Christensen CL, Bilenberg N.

Ugeskr Laeger. 2009 Aug 10;171(33):2265-8. Review. Danish.

PMID:
19732503
36.

Process evaluation results from the Eating for a Healthy Life study.

Hart A Jr, Bowen DJ, Christensen CL, Mafune R, Campbell MK, Saleeba A, Kuniyuki A, Beresford SA.

Am J Health Promot. 2009 May-Jun;23(5):324-7. doi: 10.4278/ajhp.07022818.

PMID:
19445435
37.

Specifically targeted gene therapy for small-cell lung cancer.

Christensen CL, Zandi R, Gjetting T, Cramer F, Poulsen HS.

Expert Rev Anticancer Ther. 2009 Apr;9(4):437-52. doi: 10.1586/era.09.10.

PMID:
19374598
38.

Disseminating a successful dietary intervention to faith communities: feasibility of using staff contact and encouragement to increase uptake.

Hannon PA, Bowen DJ, Christensen CL, Kuniyuki A.

J Nutr Educ Behav. 2008 May-Jun;40(3):175-80. doi: 10.1016/j.jneb.2007.09.001.

PMID:
18457786
39.

Barley aldose reductase: structure, cofactor binding, and substrate recognition in the aldo/keto reductase 4C family.

Olsen JG, Pedersen L, Christensen CL, Olsen O, Henriksen A.

Proteins. 2008 May 15;71(3):1572-81. doi: 10.1002/prot.21996. No abstract available.

PMID:
18300247
40.

Recruitment of religious organisations into a community-based health promotion programme.

Christensen CL, Bowen DJ, Hart A Jr, Kuniyuki A, Saleeba AE, Campbell MK.

Health Soc Care Community. 2005 Jul;13(4):313-22.

PMID:
15969702
41.

Baseline data and design for a randomized intervention study of dietary change in religious organizations.

Bowen DJ, Beresford SA, Vu T, Feng Z, Tinker L, Hart A Jr, Christensen CL, McLerran D, Satia-Abouta J, Campbell M.

Prev Med. 2004 Sep;39(3):602-11.

PMID:
15313101
42.

Anti-Xa stability of diluted enoxaparin for use in pediatrics.

Dager WE, Gosselin RC, King JH, Christensen CL, Owings JT, Larkin EC.

Ann Pharmacother. 2004 Apr;38(4):569-73. Epub 2004 Feb 24.

PMID:
14982984
43.

Further development of the cassette-based pYC plasmid system by incorporation of the dominant hph, nat and AUR1-C gene markers and the lacZ reporter system.

Hansen J, Felding T, Johannesen PF, Piskur J, Christensen CL, Olesen K.

FEMS Yeast Res. 2003 Dec;4(3):323-7.

44.

Physical activity, physiological, and psychomotor performance: a study of variously active older adult men.

Christensen CL, Payne VG, Wughalter EH, Yan JH, Henehan M, Jones R.

Res Q Exerc Sport. 2003 Jun;74(2):136-42.

PMID:
12848226
45.
46.

Viral vector-mediated gene expression in olfactory ensheathing glia implants in the lesioned rat spinal cord.

Ruitenberg MJ, Plant GW, Christensen CL, Blits B, Niclou SP, Harvey AR, Boer GJ, Verhaagen J.

Gene Ther. 2002 Jan;9(2):135-46.

47.

[Complications in two children with acute lymphatic leukemia caused by vaccination against varicella zoster virus].

Christensen CL, Poulsen A, Böttiger B, Kirk M, Andersen HK, Schmiegelow K.

Ugeskr Laeger. 1999 Feb 8;161(6):794-6. Danish.

PMID:
10068350
48.

Individualized gonadotropin regimens for follicular stimulation in macaques during in vitro fertilization (IVF) cycles.

Zelinski-Wooten MB, Alexander M, Christensen CL, Wolf DP, Hess DL, Stouffer RL.

J Med Primatol. 1994 Sep;23(7):367-74.

PMID:
7731026
49.

The physiological effects of step training with and without handweights.

Kravitz L, Cisar CJ, Christensen CL, Setterlund SS.

J Sports Med Phys Fitness. 1993 Dec;33(4):348-58.

PMID:
8035583
50.

Physiological and perceptual responses of women to equivalent power outputs on the bicycle ergometer and treadmill.

Christensen CL, Ruhling RO.

J Sports Med Phys Fitness. 1983 Dec;23(4):436-44. No abstract available.

PMID:
6677810

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