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Items: 1 to 50 of 100

1.

Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.

Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T, Faivre E, Ferguson D, Buchanan FG, Martin RL, Torrent M, Chiang GG, Karukurichi K, Langston JW, Weinert BT, Choudhary C, de Vries P, Kluge AF, Patane MA, Van Drie JH, Wang C, McElligott D, Kesicki EA, Marmorstein R, Sun C, Cole PA, Rosenberg SH, Michaelides MR, Lai A, Bromberg KD.

Nature. 2018 May 16. doi: 10.1038/s41586-018-0111-5. [Epub ahead of print]

PMID:
29769713
2.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

Gupta R, Somyajit K, Narita T, Maskey E, Stanlie A, Kremer M, Typas D, Lammers M, Mailand N, Nussenzweig A, Lukas J, Choudhary C.

Cell. 2018 May 3;173(4):972-988.e23. doi: 10.1016/j.cell.2018.03.050. Epub 2018 Apr 12.

PMID:
29656893
3.

Isoniazid induced early-onset of motor dominant neuropathy and treatment with high dose of pyridoxine.

Choudhary CR, Kumari J, Advani M.

Indian J Tuberc. 2018 Apr;65(2):175-176. doi: 10.1016/j.ijtb.2017.04.004. Epub 2017 May 3. No abstract available.

PMID:
29579435
4.

p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage.

Borisova ME, Voigt A, Tollenaere MAX, Sahu SK, Juretschke T, Kreim N, Mailand N, Choudhary C, Bekker-Jensen S, Akutsu M, Wagner SA, Beli P.

Nat Commun. 2018 Mar 9;9(1):1017. doi: 10.1038/s41467-018-03417-3.

5.

lncRNA Panct1 Maintains Mouse Embryonic Stem Cell Identity by Regulating TOBF1 Recruitment to Oct-Sox Sequences in Early G1.

Chakraborty D, Paszkowski-Rogacz M, Berger N, Ding L, Mircetic J, Fu J, Iesmantavicius V, Choudhary C, Anastassiadis K, Stewart AF, Buchholz F.

Cell Rep. 2017 Dec 12;21(11):3012-3021. doi: 10.1016/j.celrep.2017.11.045.

6.

Redox-sensitive alteration of replisome architecture safeguards genome integrity.

Somyajit K, Gupta R, Sedlackova H, Neelsen KJ, Ochs F, Rask MB, Choudhary C, Lukas J.

Science. 2017 Nov 10;358(6364):797-802. doi: 10.1126/science.aao3172.

PMID:
29123070
7.

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.

Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T, Faivre E, Ferguson D, Buchanan FG, Martin RL, Torrent M, Chiang GG, Karukurichi K, Langston JW, Weinert BT, Choudhary C, de Vries P, Van Drie JH, McElligott D, Kesicki E, Marmorstein R, Sun C, Cole PA, Rosenberg SH, Michaelides MR, Lai A, Bromberg KD.

Nature. 2017 Oct 5;550(7674):128-132. doi: 10.1038/nature24028. Epub 2017 Sep 27. Erratum in: Nature. 2018 May 16;:.

PMID:
28953875
8.

Accurate Quantification of Site-specific Acetylation Stoichiometry Reveals the Impact of Sirtuin Deacetylase CobB on the E. coli Acetylome.

Weinert BT, Satpathy S, Hansen BK, Lyon D, Jensen LJ, Choudhary C.

Mol Cell Proteomics. 2017 May;16(5):759-769. doi: 10.1074/mcp.M117.067587. Epub 2017 Mar 2.

9.

Deubiquitylating enzyme USP9x regulates hippo pathway activity by controlling angiomotin protein turnover.

Thanh Nguyen H, Andrejeva D, Gupta R, Choudhary C, Hong X, Eichhorn PJ, Loya AC, Cohen SM.

Cell Discov. 2016 Mar 29;2:16001. doi: 10.1038/celldisc.2016.1. eCollection 2016.

10.

SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes.

Wagner SA, Satpathy S, Beli P, Choudhary C.

EMBO J. 2016 Sep 1;35(17):1868-84. doi: 10.15252/embj.201694300. Epub 2016 Jun 15.

11.

Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells.

Ding L, Paszkowski-Rogacz M, Winzi M, Chakraborty D, Theis M, Singh S, Ciotta G, Poser I, Roguev A, Chu WK, Choudhary C, Mann M, Stewart AF, Krogan N, Buchholz F.

Cell Syst. 2015 Aug 26;1(2):141-51. doi: 10.1016/j.cels.2015.08.002. Epub 2015 Aug 26.

12.

Progressive Multifocal Leukoencephalopathy in a Lung Transplant Recipient: Isolation of John Cunningham (JC) Virus from Bronchoalveolar Lavage.

Panchabhai TS, Choudhary C, Isada C, Folch E, Mehta AC.

J Glob Infect Dis. 2016 Jan-Mar;8(1):51-4. doi: 10.4103/0974-777X.176150.

13.

Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance.

Silva S, Altmannova V, Luke-Glaser S, Henriksen P, Gallina I, Yang X, Choudhary C, Luke B, Krejci L, Lisby M.

Genes Dev. 2016 Mar 15;30(6):700-17. doi: 10.1101/gad.276204.115. Epub 2016 Mar 10.

14.

The Spindle Assembly Checkpoint Is Not Essential for Viability of Human Cells with Genetically Lowered APC/C Activity.

Wild T, Larsen MS, Narita T, Schou J, Nilsson J, Choudhary C.

Cell Rep. 2016 Mar 1;14(8):1829-40. doi: 10.1016/j.celrep.2016.01.060. Epub 2016 Feb 18.

15.

A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex.

Starnes LM, Su D, Pikkupeura LM, Weinert BT, Santos MA, Mund A, Soria R, Cho YW, Pozdnyakova I, Kubec Højfeldt M, Vala A, Yang W, López-Méndez B, Lee JE, Peng W, Yuan J, Ge K, Montoya G, Nussenzweig A, Choudhary C, Daniel JA.

Genes Dev. 2016 Jan 15;30(2):149-63. doi: 10.1101/gad.268797.115. Epub 2016 Jan 7.

16.

Avoiding abundance bias in the functional annotation of post-translationally modified proteins.

Schölz C, Lyon D, Refsgaard JC, Jensen LJ, Choudhary C, Weinert BT.

Nat Methods. 2015 Nov;12(11):1003-4. doi: 10.1038/nmeth.3621. No abstract available.

PMID:
26513550
17.

Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.

Thorslund T, Ripplinger A, Hoffmann S, Wild T, Uckelmann M, Villumsen B, Narita T, Sixma TK, Choudhary C, Bekker-Jensen S, Mailand N.

Nature. 2015 Nov 19;527(7578):389-93. doi: 10.1038/nature15401. Epub 2015 Oct 21.

PMID:
26503038
18.

Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae.

Weinert BT, Iesmantavicius V, Moustafa T, Schölz C, Wagner SA, Magnes C, Zechner R, Choudhary C.

Mol Syst Biol. 2015 Oct 26;11(10):833. doi: 10.15252/msb.156513. No abstract available.

19.

Analysis of acetylation stoichiometry suggests that SIRT3 repairs nonenzymatic acetylation lesions.

Weinert BT, Moustafa T, Iesmantavicius V, Zechner R, Choudhary C.

EMBO J. 2015 Nov 3;34(21):2620-32. doi: 10.15252/embj.201591271. Epub 2015 Sep 9.

20.

Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits.

Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M.

Elife. 2015 Sep 1;4:e08153. doi: 10.7554/eLife.08153.

21.

Evaluation of Thyroid Bed Nodules on Ultrasonography after Total Thyroidectomy: Risk for Loco-Regional Recurrence of Thyroid Cancer.

Choudhary C, Wartofsky L, Tefera E, Burman KD.

Eur Thyroid J. 2015 Jun;4(2):106-14. doi: 10.1159/000431317. Epub 2015 Jun 11.

22.

Presence of rash in a catastrophic condition.

Bandyopadhyay D, Panchabhai TS, Choudhary C.

J Emerg Trauma Shock. 2015 Jul-Sep;8(3):170-1. doi: 10.4103/0974-2700.160739. No abstract available.

23.

Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation.

Satpathy S, Wagner SA, Beli P, Gupta R, Kristiansen TA, Malinova D, Francavilla C, Tolar P, Bishop GA, Hostager BS, Choudhary C.

Mol Syst Biol. 2015 Jun 2;11(6):810. doi: 10.15252/msb.20145880.

24.

Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control.

Gallina I, Colding C, Henriksen P, Beli P, Nakamura K, Offman J, Mathiasen DP, Silva S, Hoffmann E, Groth A, Choudhary C, Lisby M.

Nat Commun. 2015 Mar 30;6:6533. doi: 10.1038/ncomms7533.

25.

Acetylation site specificities of lysine deacetylase inhibitors in human cells.

Schölz C, Weinert BT, Wagner SA, Beli P, Miyake Y, Qi J, Jensen LJ, Streicher W, McCarthy AR, Westwood NJ, Lain S, Cox J, Matthias P, Mann M, Bradner JE, Choudhary C.

Nat Biotechnol. 2015 Apr;33(4):415-23. doi: 10.1038/nbt.3130. Epub 2015 Mar 9.

PMID:
25751058
26.

FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51.

Chu WK, Payne MJ, Beli P, Hanada K, Choudhary C, Hickson ID.

Nat Commun. 2015 Jan 14;6:5931. doi: 10.1038/ncomms6931.

PMID:
25585578
27.

Ubiquitin-SUMO circuitry controls activated fanconi anemia ID complex dosage in response to DNA damage.

Gibbs-Seymour I, Oka Y, Rajendra E, Weinert BT, Passmore LA, Patel KJ, Olsen JV, Choudhary C, Bekker-Jensen S, Mailand N.

Mol Cell. 2015 Jan 8;57(1):150-64. doi: 10.1016/j.molcel.2014.12.001. Epub 2014 Dec 31.

28.

Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells.

Bursomanno S, Beli P, Khan AM, Minocherhomji S, Wagner SA, Bekker-Jensen S, Mailand N, Choudhary C, Hickson ID, Liu Y.

DNA Repair (Amst). 2015 Jan;25:84-96. doi: 10.1016/j.dnarep.2014.10.011. Epub 2014 Nov 25.

PMID:
25497329
29.

Development and characterization of metal oxide nanoparticles for the delivery of anticancer drug.

Sharma H, Kumar K, Choudhary C, Mishra PK, Vaidya B.

Artif Cells Nanomed Biotechnol. 2016;44(2):672-9. doi: 10.3109/21691401.2014.978980. Epub 2014 Nov 19.

PMID:
25406734
30.

A quantitative 14-3-3 interaction screen connects the nuclear exosome targeting complex to the DNA damage response.

Blasius M, Wagner SA, Choudhary C, Bartek J, Jackson SP.

Genes Dev. 2014 Sep 15;28(18):1977-82. doi: 10.1101/gad.246272.114. Epub 2014 Sep 4.

31.

UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells.

Oka Y, Varmark H, Vitting-Seerup K, Beli P, Waage J, Hakobyan A, Mistrik M, Choudhary C, Rohde M, Bekker-Jensen S, Mailand N.

EMBO Rep. 2014 Sep;15(9):956-64. doi: 10.15252/embr.201438679. Epub 2014 Aug 4.

32.

Another Case of Pulmonary Edema or May Be Not: An Unusual Presentation of Metastatic Melanoma.

Bandyopadhyay D, Vijhani P, Farver C, Choudhary C.

World J Oncol. 2014 Aug;5(4):183-186. doi: 10.14740/wjon734w. Epub 2014 Aug 25.

33.

Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β.

D'Souza RC, Knittle AM, Nagaraj N, van Dinther M, Choudhary C, ten Dijke P, Mann M, Sharma K.

Sci Signal. 2014 Jul 22;7(335):rs5. doi: 10.1126/scisignal.2004856.

PMID:
25056879
34.

The growing landscape of lysine acetylation links metabolism and cell signalling.

Choudhary C, Weinert BT, Nishida Y, Verdin E, Mann M.

Nat Rev Mol Cell Biol. 2014 Aug;15(8):536-50. doi: 10.1038/nrm3841. Review.

PMID:
25053359
35.

Convergence of ubiquitylation and phosphorylation signaling in rapamycin-treated yeast cells.

Iesmantavicius V, Weinert BT, Choudhary C.

Mol Cell Proteomics. 2014 Aug;13(8):1979-92. doi: 10.1074/mcp.O113.035683. Epub 2014 Jun 24.

36.

Stress in telephone helpline nurses is associated with failures of concentration, attention and memory, and with more conservative referral decisions.

Allan JL, Farquharson B, Johnston DW, Jones MC, Choudhary CJ, Johnston M.

Br J Psychol. 2014 May;105(2):200-13. doi: 10.1111/bjop.12030. Epub 2013 Mar 21.

PMID:
24754808
37.

Sustained Release of Diltiazem Hydrochloride from Cross-linked Biodegradable IPN Hydrogel Beads of Pectin and Modified Xanthan Gum.

Giri TK, Choudhary C, Alexander A, Ajazuddin, Badwaik H, Tripathy M, Tripathi DK.

Indian J Pharm Sci. 2013 Nov;75(6):619-27.

38.

Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae.

Weinert BT, Iesmantavicius V, Moustafa T, Schölz C, Wagner SA, Magnes C, Zechner R, Choudhary C.

Mol Syst Biol. 2014 Jan 30;10:716. doi: 10.1002/msb.134766. Print 2014. Erratum in: Mol Syst Biol. 2015;11(10):833.

39.

Specificity and commonality of the phosphoinositide-binding proteome analyzed by quantitative mass spectrometry.

Jungmichel S, Sylvestersen KB, Choudhary C, Nguyen S, Mann M, Nielsen ML.

Cell Rep. 2014 Feb 13;6(3):578-91. doi: 10.1016/j.celrep.2013.12.038. Epub 2014 Jan 23.

40.

A patient with acute COPD exacerbation and shock.

Narula T, Raman D, Wiesen J, Choudhary C, Reddy AJ, Moghekar A.

Chest. 2013 Dec;144(6):e1-e3. doi: 10.1378/chest.13-1412. No abstract available.

PMID:
24297150
41.

A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis.

Villumsen BH, Danielsen JR, Povlsen L, Sylvestersen KB, Merdes A, Beli P, Yang YG, Choudhary C, Nielsen ML, Mailand N, Bekker-Jensen S.

EMBO J. 2013 Nov 27;32(23):3029-40. doi: 10.1038/emboj.2013.223. Epub 2013 Oct 11.

42.

Prospects of pharmaceuticals and biopharmaceuticals loaded microparticles prepared by double emulsion technique for controlled delivery.

Giri TK, Choudhary C, Ajazuddin, Alexander A, Badwaik H, Tripathi DK.

Saudi Pharm J. 2013 Apr;21(2):125-41. doi: 10.1016/j.jsps.2012.05.009. Epub 2012 May 26.

43.

Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation.

Weinert BT, Schölz C, Wagner SA, Iesmantavicius V, Su D, Daniel JA, Choudhary C.

Cell Rep. 2013 Aug 29;4(4):842-51. doi: 10.1016/j.celrep.2013.07.024. Epub 2013 Aug 15.

44.

A patient with lung cancer presenting with respiratory failure and shock.

Wiesen J, Raman D, Adams J, Choudhary C, Moghekar A.

Chest. 2013 Jul;144(1):e1-e4. doi: 10.1378/chest.13-0375. No abstract available.

PMID:
23880698
45.

Acetyl-phosphate is a critical determinant of lysine acetylation in E. coli.

Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.

Mol Cell. 2013 Jul 25;51(2):265-72. doi: 10.1016/j.molcel.2013.06.003. Epub 2013 Jul 3.

46.

OTULIN restricts Met1-linked ubiquitination to control innate immune signaling.

Fiil BK, Damgaard RB, Wagner SA, Keusekotten K, Fritsch M, Bekker-Jensen S, Mailand N, Choudhary C, Komander D, Gyrd-Hansen M.

Mol Cell. 2013 Jun 27;50(6):818-830. doi: 10.1016/j.molcel.2013.06.004.

47.

RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response.

Poulsen SL, Hansen RK, Wagner SA, van Cuijk L, van Belle GJ, Streicher W, Wikström M, Choudhary C, Houtsmuller AB, Marteijn JA, Bekker-Jensen S, Mailand N.

J Cell Biol. 2013 Jun 10;201(6):797-807. doi: 10.1083/jcb.201212075.

48.

Broncho-vascular fistulas from self-expanding metallic stents: A retrospective case review.

Choudhary C, Bandyopadhyay D, Salman R, Gildea T, Mehta A.

Ann Thorac Med. 2013 Apr;8(2):116-20. doi: 10.4103/1817-1737.109830.

49.

Takotsubo cardiomyopathy associated with thyrotoxicosis: a case report and review of the literature.

Eliades M, El-Maouche D, Choudhary C, Zinsmeister B, Burman KD.

Thyroid. 2014 Feb;24(2):383-9. doi: 10.1089/thy.2012.0384. Epub 2013 Jul 25. Review.

50.

Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.

Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.

PLoS One. 2012;7(12):e50545. doi: 10.1371/journal.pone.0050545. Epub 2012 Dec 7.

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