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Chalcomoracin is a potent anticancer agent acting through triggering Oxidative stress via a mitophagy- and paraptosis-dependent mechanism.

Han H, Chou CC, Li R, Liu J, Zhang L, Zhu W, Hu J, Yang B, Tian J.

Sci Rep. 2018 Jun 22;8(1):9566. doi: 10.1038/s41598-018-27724-3.


Ethyl Acetate Extract of Scindapsus cf. hederaceus Exerts the Inhibitory Bioactivity on Human Non-Small Cell Lung Cancer Cells through Modulating ER Stress.

Chou CK, Liu W, Hong YJ, Dahms HU, Chiu CH, Chang WT, Chien CM, Yen CH, Cheng YB, Chiu CC.

Int J Mol Sci. 2018 Jun 21;19(7). pii: E1832. doi: 10.3390/ijms19071832.


Associations of genetic variations of the endothelial nitric oxide synthase gene and environmental carcinogens with oral cancer susceptibility and development.

Su CW, Chien MH, Lin CW, Chen MK, Chow JM, Chuang CY, Chou CH, Liu YC, Yang SF.

Nitric Oxide. 2018 Jun 19. pii: S1089-8603(18)30134-4. doi: 10.1016/j.niox.2018.06.005. [Epub ahead of print]


Proteomic determination of the lysine acetylome and phosphoproteome in the rat native inner medullary collecting duct.

Hyndman KA, Yang CR, Jung HJ, Umejiego EN, Chou CL, Knepper MA.

Physiol Genomics. 2018 Jun 22. doi: 10.1152/physiolgenomics.00029.2018. [Epub ahead of print]


The association of sleep duration and sleep quality with non-alcoholic fatty liver disease in a Taiwanese population.

Chou YT, Cheng HJ, Wu JS, Yang YC, Chou CY, Chang CJ, Lu FH.

Obes Res Clin Pract. 2018 Jun 18. pii: S1871-403X(18)30296-5. doi: 10.1016/j.orcp.2018.05.002. [Epub ahead of print]


Inhomogeneous Down-regulation of INa underlies piceatannol pro-arrhythmic Mechanism in regional ischemia-reperfusion.

Chang PC, Huang YC, Lee HL, Chang GJ, Chu Y, Wen MS, Chou CC.

Pacing Clin Electrophysiol. 2018 Jun 21. doi: 10.1111/pace.13424. [Epub ahead of print]


Role of activating transcription factor 3 in fructose-induced metabolic syndrome in mice.

Chou CL, Li CH, Lin H, Liao MH, Wu CC, Chen JS, Sue YM, Fang TC.

Hypertens Res. 2018 Jun 12. doi: 10.1038/s41440-018-0058-9. [Epub ahead of print]


A flow-proteometric platform for analyzing protein concentration (FAP): Proof of concept for quantification of PD-L1 protein in cells and tissues.

Chou CK, Huang PJ, Tsou PH, Wei Y, Lee HH, Wang YN, Liu YL, Shi C, Yeh HC, Kameoka J, Hung MC.

Biosens Bioelectron. 2018 May 29;117:97-103. doi: 10.1016/j.bios.2018.05.053. [Epub ahead of print]


Glycan-Directed Grafting-from Polymerization of Immunoglobulin G: Site-Selectively Modified IgG-Polymer Conjugates with Preserved Biological Activity.

Chou CH, Lin PC.

Biomacromolecules. 2018 Jun 21. doi: 10.1021/acs.biomac.8b00669. [Epub ahead of print]


Impacts of WNT1-inducible signaling pathway protein 1 polymorphism on hepatocellular carcinoma development.

Chen CT, Lee HL, Chiou HL, Chou CH, Wang PH, Yang SF, Chou YE.

PLoS One. 2018 Jun 11;13(6):e0198967. doi: 10.1371/journal.pone.0198967. eCollection 2018.


Cardiovascular and psychological responses to voluntary recall of trauma in posttraumatic stress disorder.

Chou CY, La Marca R, Steptoe A, Brewin CR.

Eur J Psychotraumatol. 2018 Jun 4;9(1):1472988. doi: 10.1080/20008198.2018.1472988. eCollection 2018.


Detail-oriented visual processing style: Its role in the relationships between early life adversity and hoarding-related dysfunctions.

Chou CY, Mackin RS, Delucchi KL, Mathews CA.

Psychiatry Res. 2018 May 23;267:30-36. doi: 10.1016/j.psychres.2018.05.053. [Epub ahead of print]


Epidemiology and risk factors for invasive fungal infections during induction chemotherapy for newly diagnosed acute myeloid leukemia: A retrospective cohort study.

Lien MY, Chou CH, Lin CC, Bai LY, Chiu CF, Yeh SP, Ho MW.

PLoS One. 2018 Jun 8;13(6):e0197851. doi: 10.1371/journal.pone.0197851. eCollection 2018.


The Association Between Septicemia and the Risk of Multiple Sclerosis: a Nationwide Register-based Retrospective Cohort Study in Taiwan.

Tsai CL, Lee JT, Lien LM, Lin CC, Tsai IJ, Sung YF, Chou CH, Yang FC, Tsai CK, Wang IK, Tseng CH, Hsu CY.

QJM. 2018 Jun 6. doi: 10.1093/qjmed/hcy123. [Epub ahead of print]


Extension of C. elegans lifespan using the ·NO-delivery dinitrosyl iron complexes.

Huang HW, Lin YH, Lin MH, Huang YR, Chou CH, Hong HC, Wang MR, Tseng YT, Liao PC, Chung MC, Ma YJ, Wu SC, Chuang YJ, Wang HD, Wang YM, Huang HD, Lu TT, Liaw WF.

J Biol Inorg Chem. 2018 Jul;23(5):775-784. doi: 10.1007/s00775-018-1569-1. Epub 2018 Jun 1.


Impact of Different Serum Potassium Levels on Postresuscitation Heart Function and Hemodynamics in Patients with Nontraumatic Out-of-Hospital Cardiac Arrest.

Lin YR, Syue YJ, Lee TH, Chou CC, Chang CF, Li CJ.

Bioinorg Chem Appl. 2018 Apr 5;2018:5825929. doi: 10.1155/2018/5825929. eCollection 2018.


Tobacco Marketing and Subsequent Use of Cigarettes, E-cigarettes and Hookah in Adolescents.

Cruz TB, McConnell R, Low BW, Unger JB, Pentz MA, Urman R, Berhane K, Chou CP, Liu F, Barrington-Trimis J.

Nicotine Tob Res. 2018 May 28. doi: 10.1093/ntr/nty107. [Epub ahead of print]


14 day sequential therapy versus 10 day bismuth quadruple therapy containing high-dose esomeprazole in the first-line and second-line treatment of Helicobacter pylori: a multicentre, non-inferiority, randomized trial.

Liou JM, Chen CC, Fang YJ, Chen PY, Chang CY, Chou CK, Chen MJ, Tseng CH, Lee JY, Yang TH, Chiu MC, Yu JJ, Kuo CC, Luo JC, Hsu WF, Hu WH, Tsai MH, Lin JT, Shun CT, Twu G, Lee YC, Bair MJ, Wu MS; Taiwan Gastrointestinal Disease and Helicobacter Consortium.

J Antimicrob Chemother. 2018 May 29. doi: 10.1093/jac/dky183. [Epub ahead of print]


Depletion of Cholesterol Reduces ENaC Activity by Decreasing Phosphatidylinositol-4,5-Bisphosphate in Microvilli.

Zhai YJ, Liu BC, Wei SP, Chou CF, Wu MM, Song BL, Linck VA, Zou L, Zhang S, Li XQ, Zhang ZR, Ma HP.

Cell Physiol Biochem. 2018 May 24;47(3):1051-1059. doi: 10.1159/000490170. [Epub ahead of print]


Global-cognitive health metrics: A novel approach for assessing cognition impairment in adult population.

Tsai CK, Kao TW, Lee JT, Wang CC, Chou CH, Liang CS, Yang FC, Chen WL.

PLoS One. 2018 May 29;13(5):e0197691. doi: 10.1371/journal.pone.0197691. eCollection 2018.


Parameter uncertainty quantification using surrogate models applied to a spatial model of yeast mating polarization.

Renardy M, Yi TM, Xiu D, Chou CS.

PLoS Comput Biol. 2018 May 29;14(5):e1006181. doi: 10.1371/journal.pcbi.1006181. eCollection 2018 May.


Hematuria as the only symptom at initial presentation of hypovolemic shock caused by ruptured renal arteriovenous malformations.

Chang YJ, Chou CC, Chang CF, Lin YR.

Am J Emerg Med. 2018 May 20. pii: S0735-6757(18)30405-4. doi: 10.1016/j.ajem.2018.05.028. [Epub ahead of print]


Discovery of Novel Pazopanib-Based HDAC and VEGFR Dual Inhibitors Targeting Cancer Epigenetics and Angiogenesis Simultaneously.

Zang J, Liang X, Huang Y, Jia Y, Li X, Xu W, Chou CJ, Zhang Y.

J Med Chem. 2018 Jun 7. doi: 10.1021/acs.jmedchem.8b00384. [Epub ahead of print]


Linkage of the Nit1C gene cluster to bacterial cyanide assimilation as a nitrogen source.

Jones LB, Ghosh P, Lee JH, Chou CN, Kunz DA.

Microbiology. 2018 May 21. doi: 10.1099/mic.0.000668. [Epub ahead of print]


Increased platelet factor 4 and aberrant permeability of follicular fluid in PCOS.

Huang CC, Chou CH, Chen SU, Ho HN, Yang YS, Chen MJ.

J Formos Med Assoc. 2018 May 17. pii: S0929-6646(17)30829-X. doi: 10.1016/j.jfma.2018.05.002. [Epub ahead of print]


Antibody-assisted target identification reveals afatinib, an EGFR covalent inhibitor, down-regulating ribonucleotide reductase.

Yu CH, Chou CC, Tu HF, Huang WC, Ho YY, Khoo KH, Lee MS, Chang GD.

Oncotarget. 2018 Apr 20;9(30):21512-21529. doi: 10.18632/oncotarget.25177. eCollection 2018 Apr 20.


The aquatic animals' transcriptome resource for comparative functional analysis.

Chou CH, Huang HY, Huang WC, Hsu SD, Hsiao CD, Liu CY, Chen YH, Liu YC, Huang WY, Lee ML, Chen YC, Huang HD.

BMC Genomics. 2018 May 9;19(Suppl 2):103. doi: 10.1186/s12864-018-4463-x.


Honokiol, a Polyphenol Natural Compound, Attenuates Cisplatin-Induced Acute Cytotoxicity in Renal Epithelial Cells Through Cellular Oxidative Stress and Cytoskeleton Modulations.

Wang TJ, Liu HT, Lai YH, Jan TR, Nomura N, Chang HW, Chou CC, Lee YJ, Tsai PJ.

Front Pharmacol. 2018 Apr 24;9:357. doi: 10.3389/fphar.2018.00357. eCollection 2018.


A novel long non-coding RNA linc-ZNF469-3 promotes lung metastasis through miR-574-5p-ZEB1 axis in triple negative breast cancer.

Wang PS, Chou CH, Lin CH, Yao YC, Cheng HC, Li HY, Chuang YC, Yang CN, Ger LP, Chen YC, Lin FC, Shen TL, Hsiao M, Lu PJ.

Oncogene. 2018 May 14. doi: 10.1038/s41388-018-0293-1. [Epub ahead of print]


GSK3β‑mediated Ser156 phosphorylation modulates a BH3‑like domain in BCL2L12 during TMZ‑induced apoptosis and autophagy in glioma cells.

Chu CW, Yang MC, Chou CH, Huang WS, Hsiao BX, Wang YT, Chiou SJ, Loh JK, Hong YR.

Int J Mol Med. 2018 Aug;42(2):905-918. doi: 10.3892/ijmm.2018.3672. Epub 2018 May 11.


Supremum of block entanglement for symmetric Gaussian states.

Kao JY, Chou CH.

Sci Rep. 2018 May 9;8(1):7394. doi: 10.1038/s41598-018-25781-2.


Risk assessment models to predict caries recurrence after oral rehabilitation under general anaesthesia: a pilot study.

Lin YT, Kalhan AC, Lin YJ, Kalhan TA, Chou CC, Gao XL, Hsu CS.

Int Dent J. 2018 May 8. doi: 10.1111/idj.12396. [Epub ahead of print]


Paradoxical Effects of Sodium-Calcium Exchanger Inhibition on Torsade de Pointes and Early Afterdepolarization in a Heart Failure Rabbit Model.

Chang PC, Lu YY, Lee HL, Lin SF, Chu Y, Wen MS, Chou CC.

J Cardiovasc Pharmacol. 2018 May 3. doi: 10.1097/FJC.0000000000000598. [Epub ahead of print]


Impact of matrix metalloproteinase-11 gene polymorphisms upon the development and progression of hepatocellular carcinoma.

Wang B, Hsu CJ, Lee HL, Chou CH, Su CM, Yang SF, Tang CH.

Int J Med Sci. 2018 Apr 3;15(6):653-658. doi: 10.7150/ijms.23733. eCollection 2018.


Development of a quantitative real-time RT-PCR assay for detecting Taiwan ferret badger rabies virus in ear tissue of ferret badgers and mice.

Hsu AP, Tseng CH, Lu YT, Shih YH, Chou CH, Chen RS, Tsai KJ, Tu WJ, Cliquet F, Tsai HJ.

J Vet Med Sci. 2018 Apr 30. doi: 10.1292/jvms.17-0539. [Epub ahead of print]


Metabolic engineering to enhance heterologous production of hyaluronic acid in Bacillus subtilis.

Westbrook AW, Ren X, Oh J, Moo-Young M, Chou CP.

Metab Eng. 2018 May;47:401-413. doi: 10.1016/j.ymben.2018.04.016. Epub 2018 Apr 23.


Associations of Common Genetic Variants on IL-17 Genes and Carotid Intima-Media Thickness.

Wu TW, Chou CL, Chen YC, Juang YL, Wang LY.

J Atheroscler Thromb. 2018 Apr 24. doi: 10.5551/jat.44453. [Epub ahead of print]


The origin of GSKIP, a multifaceted regulatory factor in the mammalian Wnt pathway.

Chou CH, Yang MC, Hsiao BX, Wang YH, Liu HF, Chiou SJ, Chuang YC, Yang CN, Lieu AS, Loh JK, Howng SL, Chou AK, Tseng CN, Cheng JT, Hong YR.

Biochim Biophys Acta. 2018 Aug;1865(8):1046-1059. doi: 10.1016/j.bbamcr.2018.04.008. Epub 2018 Apr 23.


Comparative Effectiveness of a Technology-Facilitated Depression Care Management Model in Safety-Net Primary Care Patients With Type 2 Diabetes: 6-Month Outcomes of a Large Clinical Trial.

Wu S, Ell K, Jin H, Vidyanti I, Chou CP, Lee PJ, Gross-Schulman S, Sklaroff LM, Belson D, Nezu AM, Hay J, Wang CJ, Scheib G, Di Capua P, Hawkins C, Liu P, Ramirez M, Wu BW, Richman M, Myers C, Agustines D, Dasher R, Kopelowicz A, Allevato J, Roybal M, Ipp E, Haider U, Graham S, Mahabadi V, Guterman J.

J Med Internet Res. 2018 Apr 23;20(4):e147. doi: 10.2196/jmir.7692.


Extracellular vesicle-mediated long-range communication in stressed retinal pigment epithelial cell monolayers.

Shah N, Ishii M, Brandon C, Ablonczy Z, Cai J, Liu Y, Chou CJ, Rohrer B.

Biochim Biophys Acta. 2018 Aug;1864(8):2610-2622. doi: 10.1016/j.bbadis.2018.04.016. Epub 2018 Apr 21.


Risk of developing open-angle glaucoma in patients with carotid artery stenosis: A nationwide cohort study.

Chou CC, Hsu MY, Lin CH, Lin CC, Wang CY, Shen YC, Wang IJ.

PLoS One. 2018 Apr 23;13(4):e0194533. doi: 10.1371/journal.pone.0194533. eCollection 2018.


Flexible random lasers with tunable lasing emissions.

Lee YJ, Chou CY, Yang ZP, Nguyen TBH, Yao YC, Yeh TW, Tsai MT, Kuo HC.

Nanoscale. 2018 Jun 7;10(22):10403-10411. doi: 10.1039/c8nr00229k.


Health effects of a forest environment on natural killer cells in humans: an observational pilot study.

Tsao TM, Tsai MJ, Hwang JS, Cheng WF, Wu CF, Chou CK, Su TC.

Oncotarget. 2018 Mar 27;9(23):16501-16511. doi: 10.18632/oncotarget.24741. eCollection 2018 Mar 27.


Metformin Decreases the Incidence of Pancreatic Ductal Adenocarcinoma Promoted by Diet-induced Obesity in the Conditional KrasG12D Mouse Model.

Chang HH, Moro A, Chou CEN, Dawson DW, French S, Schmidt AI, Sinnett-Smith J, Hao F, Hines OJ, Eibl G, Rozengurt E.

Sci Rep. 2018 Apr 12;8(1):5899. doi: 10.1038/s41598-018-24337-8.


The sequence of cortical activity inferred by response latency variability in the human ventral pathway of face processing.

Lin JL, Silva-Pereyra J, Chou CC, Lin FH.

Sci Rep. 2018 Apr 11;8(1):5836. doi: 10.1038/s41598-018-23942-x.


Inspiratory muscle training for reducing postoperative pulmonary complications: A simple method that we hope is effective.

Chou CH, Chen CY.

J Thorac Cardiovasc Surg. 2018 Mar 17. pii: S0022-5223(18)30810-9. doi: 10.1016/j.jtcvs.2018.03.031. [Epub ahead of print] No abstract available.


Structural basis of interaction between dimeric cyclophilin 1 and Myb1 transcription factor in Trichomonas vaginalis.

Martin T, Lou YC, Chou CC, Wei SY, Sadotra S, Cho CC, Lin MH, Tai JH, Hsu CH, Chen C.

Sci Rep. 2018 Apr 3;8(1):5410. doi: 10.1038/s41598-018-23821-5.


Re(de)fining Innate Lymphocyte Lineages in the Face of Cancer.

Chou C, Li MO.

Cancer Immunol Res. 2018 Apr;6(4):372-377. doi: 10.1158/2326-6066.CIR-17-0440. Review.


Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer.

Wang YN, Lee HH, Chou CK, Yang WH, Wei Y, Chen CT, Yao J, Hsu JL, Zhu C, Ying H, Ye Y, Wang WJ, Lim SO, Xia W, Ko HW, Liu X, Liu CG, Wu X, Wang H, Li D, Prakash LR, Katz MH, Kang Y, Kim M, Fleming JB, Fogelman D, Javle M, Maitra A, Hung MC.

Cancer Cell. 2018 Apr 9;33(4):752-769.e8. doi: 10.1016/j.ccell.2018.02.012. Epub 2018 Mar 29.


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