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Items: 18


Natural killer cell immunotherapies against cancer: checkpoint inhibitors and more.

Chiossone L, Vienne M, Kerdiles YM, Vivier E.

Semin Immunol. 2017 Jun;31:55-63. doi: 10.1016/j.smim.2017.08.003. Epub 2017 Sep 22. Review.


Immune checkpoints on innate lymphoid cells.

Chiossone L, Vivier E.

J Exp Med. 2017 Jun 5;214(6):1561-1563. doi: 10.1084/jem.20170763. Epub 2017 May 17.


IL15 induces a potent antitumor activity in NK cells isolated from malignant pleural effusions and overcomes the inhibitory effect of pleural fluid.

Croxatto D, Martini S, Chiossone L, Scordamaglia F, Simonassi CF, Moretta L, Mingari MC, Vacca P.

Oncoimmunology. 2017 Feb 17;6(4):e1293210. doi: 10.1080/2162402X.2017.1293210. eCollection 2017.


Mesenchymal Stromal Cells Induce Peculiar Alternatively Activated Macrophages Capable of Dampening Both Innate and Adaptive Immune Responses.

Chiossone L, Conte R, Spaggiari GM, Serra M, Romei C, Bellora F, Becchetti F, Andaloro A, Moretta L, Bottino C.

Stem Cells. 2016 Jul;34(7):1909-21. doi: 10.1002/stem.2369. Epub 2016 Apr 14.


Murine peripheral NK-cell populations originate from site-specific immature NK cells more than from BM-derived NK cells.

Pinhas N, Sternberg-Simon M, Chiossone L, Shahaf G, Walzer T, Vivier E, Mehr R.

Eur J Immunol. 2016 May;46(5):1258-70. doi: 10.1002/eji.201545847. Epub 2016 Mar 31.


Unique Eomes(+) NK Cell Subsets Are Present in Uterus and Decidua During Early Pregnancy.

Montaldo E, Vacca P, Chiossone L, Croxatto D, Loiacono F, Martini S, Ferrero S, Walzer T, Moretta L, Mingari MC.

Front Immunol. 2016 Jan 7;6:646. doi: 10.3389/fimmu.2015.00646. eCollection 2015.


In vivo generation of decidual natural killer cells from resident hematopoietic progenitors.

Chiossone L, Vacca P, Orecchia P, Croxatto D, Damonte P, Astigiano S, Barbieri O, Bottino C, Moretta L, Mingari MC.

Haematologica. 2014 Mar;99(3):448-57. doi: 10.3324/haematol.2013.091421. Epub 2013 Oct 31.


Protection from inflammatory organ damage in a murine model of hemophagocytic lymphohistiocytosis using treatment with IL-18 binding protein.

Chiossone L, Audonnet S, Chetaille B, Chasson L, Farnarier C, Berda-Haddad Y, Jordan S, Koszinowski UH, Dalod M, Mazodier K, Novick D, Dinarello CA, Vivier E, Kaplanski G.

Front Immunol. 2012 Aug 8;3:239. doi: 10.3389/fimmu.2012.00239. eCollection 2012.


Dendritic cell editing by activated natural killer cells results in a more protective cancer-specific immune response.

Morandi B, Mortara L, Chiossone L, Accolla RS, Mingari MC, Moretta L, Moretta A, Ferlazzo G.

PLoS One. 2012;7(6):e39170. doi: 10.1371/journal.pone.0039170. Epub 2012 Jun 19.


Mesenchymal stem cells expanded in human platelet lysate display a decreased inhibitory capacity on T- and NK-cell proliferation and function.

Abdelrazik H, Spaggiari GM, Chiossone L, Moretta L.

Eur J Immunol. 2011 Nov;41(11):3281-90. doi: 10.1002/eji.201141542. Epub 2011 Oct 18.


Maturation of mouse NK cells is a 4-stage developmental program.

Chiossone L, Chaix J, Fuseri N, Roth C, Vivier E, Walzer T.

Blood. 2009 May 28;113(22):5488-96. doi: 10.1182/blood-2008-10-187179. Epub 2009 Feb 20.


Internalization via Antennapedia protein transduction domain of an scFv antibody toward c-Myc protein.

Avignolo C, Bagnasco L, Biasotti B, Melchiori A, Tomati V, Bauer I, Salis A, Chiossone L, Mingari MC, Orecchia P, Carnemolla B, Neri D, Zardi L, Parodi S.

FASEB J. 2008 Apr;22(4):1237-45. Epub 2007 Nov 29.


Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor.

Walzer T, Chiossone L, Chaix J, Calver A, Carozzo C, Garrigue-Antar L, Jacques Y, Baratin M, Tomasello E, Vivier E.

Nat Immunol. 2007 Dec;8(12):1337-44. Epub 2007 Oct 28.


Molecular analysis of the methylprednisolone-mediated inhibition of NK-cell function: evidence for different susceptibility of IL-2- versus IL-15-activated NK cells.

Chiossone L, Vitale C, Cottalasso F, Moretti S, Azzarone B, Moretta L, Mingari MC.

Blood. 2007 May 1;109(9):3767-75. Epub 2007 Jan 18.


Human natural killer cells undergoing in vivo differentiation after allogeneic bone marrow transplantation: analysis of the surface expression and function of activating NK receptors.

Vitale C, Chiossone L, Morreale G, Lanino E, Cottalasso F, Moretti S, Dini G, Moretta L, Mingari MC.

Mol Immunol. 2005 Feb;42(4):405-11.


The corticosteroid-induced inhibitory effect on NK cell function reflects down-regulation and/or dysfunction of triggering receptors involved in natural cytotoxicity.

Vitale C, Chiossone L, Cantoni C, Morreale G, Cottalasso F, Moretti S, Pistorio A, Haupt R, Lanino E, Dini G, Moretta L, Mingari MC.

Eur J Immunol. 2004 Nov;34(11):3028-38.


Analysis of the activating receptors and cytolytic function of human natural killer cells undergoing in vivo differentiation after allogeneic bone marrow transplantation.

Vitale C, Chiossone L, Morreale G, Lanino E, Cottalasso F, Moretti S, Dini G, Moretta L, Mingari MC.

Eur J Immunol. 2004 Feb;34(2):455-60.


Surface expression and function of p75/AIRM-1 or CD33 in acute myeloid leukemias: engagement of CD33 induces apoptosis of leukemic cells.

Vitale C, Romagnani C, Puccetti A, Olive D, Costello R, Chiossone L, Pitto A, Bacigalupo A, Moretta L, Mingari MC.

Proc Natl Acad Sci U S A. 2001 May 8;98(10):5764-9. Epub 2001 Apr 24.

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