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Items: 20


Targeting immune checkpoints potentiates immunoediting and changes the dynamics of tumor evolution.

Efremova M, Rieder D, Klepsch V, Charoentong P, Finotello F, Hackl H, Hermann-Kleiter N, Löwer M, Baier G, Krogsdam A, Trajanoski Z.

Nat Commun. 2018 Jan 2;9(1):32. doi: 10.1038/s41467-017-02424-0.


MicroRNAs and their role for T stage determination and lymph node metastasis in early colon carcinoma.

Rammer M, Webersinke G, Haitchi-Petnehazy S, Maier E, Hackl H, Charoentong P, Malli T, Steinmair M, Petzer AL, Rumpold H.

Clin Exp Metastasis. 2017 Oct;34(6-7):431-440. doi: 10.1007/s10585-017-9863-9. Epub 2017 Nov 13.


Intratumoral HPV16-Specific T Cells Constitute a Type I-Oriented Tumor Microenvironment to Improve Survival in HPV16-Driven Oropharyngeal Cancer.

Welters MJP, Ma W, Santegoets SJAM, Goedemans R, Ehsan I, Jordanova ES, van Ham VJ, van Unen V, Koning F, van Egmond SI, Charoentong P, Trajanoski Z, van der Velden LA, van der Burg SH.

Clin Cancer Res. 2018 Feb 1;24(3):634-647. doi: 10.1158/1078-0432.CCR-17-2140. Epub 2017 Oct 10.


In Silico Modeling of Immunotherapy and Stroma-Targeting Therapies in Human Colorectal Cancer.

Kather JN, Poleszczuk J, Suarez-Carmona M, Krisam J, Charoentong P, Valous NA, Weis CA, Tavernar L, Leiss F, Herpel E, Klupp F, Ulrich A, Schneider M, Marx A, Jäger D, Halama N.

Cancer Res. 2017 Nov 15;77(22):6442-6452. doi: 10.1158/0008-5472.CAN-17-2006. Epub 2017 Sep 18.


TIminer: NGS data mining pipeline for cancer immunology and immunotherapy.

Tappeiner E, Finotello F, Charoentong P, Mayer C, Rieder D, Trajanoski Z.

Bioinformatics. 2017 Oct 1;33(19):3140-3141. doi: 10.1093/bioinformatics/btx377.


Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade.

Charoentong P, Finotello F, Angelova M, Mayer C, Efremova M, Rieder D, Hackl H, Trajanoski Z.

Cell Rep. 2017 Jan 3;18(1):248-262. doi: 10.1016/j.celrep.2016.12.019.


Computational genomics tools for dissecting tumour-immune cell interactions.

Hackl H, Charoentong P, Finotello F, Trajanoski Z.

Nat Rev Genet. 2016 Jul 4;17(8):441-58. doi: 10.1038/nrg.2016.67. Review.


The colorectal cancer immune paradox revisited.

Angelova M, Charoentong P, Hackl H, Trajanoski Z.

Oncoimmunology. 2015 Aug 27;5(2):e1078058. eCollection 2016 Feb.


Serum Autoantibodies in Chronic Prostate Inflammation in Prostate Cancer Patients.

Schlick B, Massoner P, Lueking A, Charoentong P, Blattner M, Schaefer G, Marquart K, Theek C, Amersdorfer P, Zielinski D, Kirchner M, Trajanoski Z, Rubin MA, Müllner S, Schulz-Knappe P, Klocker H.

PLoS One. 2016 Feb 10;11(2):e0147739. doi: 10.1371/journal.pone.0147739. eCollection 2016.


The thioredoxin system in breast cancer cell invasion and migration.

Bhatia M, McGrath KL, Di Trapani G, Charoentong P, Shah F, King MM, Clarke FM, Tonissen KF.

Redox Biol. 2016 Aug;8:68-78. doi: 10.1016/j.redox.2015.12.004. Epub 2015 Dec 19.


Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy.

Angelova M, Charoentong P, Hackl H, Fischer ML, Snajder R, Krogsdam AM, Waldner MJ, Bindea G, Mlecnik B, Galon J, Trajanoski Z.

Genome Biol. 2015 Mar 31;16:64. doi: 10.1186/s13059-015-0620-6.


High STAT1 mRNA levels but not its tyrosine phosphorylation are associated with macrophage infiltration and bad prognosis in breast cancer.

Tymoszuk P, Charoentong P, Hackl H, Spilka R, Müller-Holzner E, Trajanoski Z, Obrist P, Revillion F, Peyrat JP, Fiegl H, Doppler W.

BMC Cancer. 2014 Apr 12;14:257. doi: 10.1186/1471-2407-14-257.


Mathematical models for translational and clinical oncology.

Gallasch R, Efremova M, Charoentong P, Hackl H, Trajanoski Z.

J Clin Bioinforma. 2013 Nov 7;3(1):23. doi: 10.1186/2043-9113-3-23.


Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts.

Greussing R, Hackl M, Charoentong P, Pauck A, Monteforte R, Cavinato M, Hofer E, Scheideler M, Neuhaus M, Micutkova L, Mueck C, Trajanoski Z, Grillari J, Jansen-Dürr P.

BMC Genomics. 2013 Apr 4;14:224. doi: 10.1186/1471-2164-14-224.


Bioinformatics for cancer immunology and immunotherapy.

Charoentong P, Angelova M, Efremova M, Gallasch R, Hackl H, Galon J, Trajanoski Z.

Cancer Immunol Immunother. 2012 Nov;61(11):1885-903. doi: 10.1007/s00262-012-1354-x. Epub 2012 Sep 18. Review.


Information technology solutions for integration of biomolecular and clinical data in the identification of new cancer biomarkers and targets for therapy.

Hackl H, Stocker G, Charoentong P, Mlecnik B, Bindea G, Galon J, Trajanoski Z.

Pharmacol Ther. 2010 Dec;128(3):488-98. doi: 10.1016/j.pharmthera.2010.08.012. Epub 2010 Sep 9. Review.


Data integration and exploration for the identification of molecular mechanisms in tumor-immune cells interaction.

Mlecnik B, Sanchez-Cabo F, Charoentong P, Bindea G, Pagès F, Berger A, Galon J, Trajanoski Z.

BMC Genomics. 2010 Feb 10;11 Suppl 1:S7. doi: 10.1186/1471-2164-11-S1-S7.


Biomolecular network reconstruction identifies T-cell homing factors associated with survival in colorectal cancer.

Mlecnik B, Tosolini M, Charoentong P, Kirilovsky A, Bindea G, Berger A, Camus M, Gillard M, Bruneval P, Fridman WH, Pagès F, Trajanoski Z, Galon J.

Gastroenterology. 2010 Apr;138(4):1429-40. doi: 10.1053/j.gastro.2009.10.057. Epub 2009 Nov 10.


Coordination of intratumoral immune reaction and human colorectal cancer recurrence.

Camus M, Tosolini M, Mlecnik B, Pagès F, Kirilovsky A, Berger A, Costes A, Bindea G, Charoentong P, Bruneval P, Trajanoski Z, Fridman WH, Galon J.

Cancer Res. 2009 Mar 15;69(6):2685-93. doi: 10.1158/0008-5472.CAN-08-2654. Epub 2009 Mar 3.


ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks.

Bindea G, Mlecnik B, Hackl H, Charoentong P, Tosolini M, Kirilovsky A, Fridman WH, Pagès F, Trajanoski Z, Galon J.

Bioinformatics. 2009 Apr 15;25(8):1091-3. doi: 10.1093/bioinformatics/btp101. Epub 2009 Feb 23.

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