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Spironolactone Versus Clonidine as a Fourth-Drug Therapy for Resistant Hypertension: The ReHOT Randomized Study (Resistant Hypertension Optimal Treatment).

Krieger EM, Drager LF, Giorgi DMA, Pereira AC, Barreto-Filho JAS, Nogueira AR, Mill JG, Lotufo PA, Amodeo C, Batista MC, Bodanese LC, Carvalho ACC, Castro I, Chaves H, Costa EAS, Feitosa GS, Franco RJS, Fuchs FD, Guimarães AC, Jardim PC, Machado CA, Magalhães ME, Mion D Jr, Nascimento RM, Nobre F, Nóbrega AC, Ribeiro ALP, Rodrigues-Sobrinho CR, Sanjuliani AF, Teixeira MDCB, Krieger JE; ReHOT Investigators.

Hypertension. 2018 Feb 20. pii: HYPERTENSIONAHA.117.10662. doi: 10.1161/HYPERTENSIONAHA.117.10662. [Epub ahead of print]


Evaluation of a Multichannel Non-Contact ECG System and Signal Quality Algorithms for Sleep Apnea Detection and Monitoring.

Castro ID, Varon C, Torfs T, Van Huffel S, Puers R, Van Hoof C.

Sensors (Basel). 2018 Feb 13;18(2). pii: E577. doi: 10.3390/s18020577.


Protein phosphatases at the nuclear envelope.

Sales Gil R, de Castro IJ, Berihun J, Vagnarelli P.

Biochem Soc Trans. 2018 Feb 19;46(1):173-182. doi: 10.1042/BST20170139. Epub 2018 Feb 6. Review.


Prognostic Value of Occult Isolated Tumour Cells within Regional Lymph Nodes of Dogs with Malignant Mammary Tumours.

Coleto AF, Wilson TM, Soares NP, Gundim LF, Castro IP, Guimarães EC, Bandarra MB, Medeiros-Ronchi AA.

J Comp Pathol. 2018 Jan;158:32-38. doi: 10.1016/j.jcpa.2017.11.001. Epub 2017 Dec 6.


Assessment of organotins and imposex in two estuaries of the northeastern Brazilian coast.

Maciel DC, Castro ÍB, de Souza JRB, Yogui GT, Fillmann G, Zanardi-Lamardo E.

Mar Pollut Bull. 2018 Jan;126:473-478. doi: 10.1016/j.marpolbul.2017.11.061. Epub 2017 Dec 22.


[From oral history to the research film: the audiovisual as a tool of the historian].

Mattos H, Abreu M, Castro I.

Hist Cienc Saude Manguinhos. 2017 Oct-Dec;24(4):1147-1160. doi: 10.1590/S0104-59702017000500016. Portuguese.


Mind the Organelle Gap - Peroxisome Contact Sites in Disease.

Castro IG, Schuldiner M, Zalckvar E.

Trends Biochem Sci. 2018 Jan 27. pii: S0968-0004(18)30001-X. doi: 10.1016/j.tibs.2018.01.001. [Epub ahead of print] Review.


A role for Mitochondrial Rho GTPase 1 (MIRO1) in motility and membrane dynamics of peroxisomes.

Castro IG, Richards DM, Metz J, Costello JL, Passmore JB, Schrader TA, Gouveia A, Ribeiro D, Schrader M.

Traffic. 2018 Jan 24. doi: 10.1111/tra.12549. [Epub ahead of print]


Antifouling booster biocide extraction from marine sediments: a fast and simple method based on vortex-assisted matrix solid-phase extraction.

Caldas SS, Soares BM, Abreu F, Castro ÍB, Fillmann G, Primel EG.

Environ Sci Pollut Res Int. 2017 Dec 27. doi: 10.1007/s11356-017-0942-x. [Epub ahead of print]


Protective effect of genetic deletion of pannexin1 in experimental mouse models of acute and chronic liver disease.

Willebrords J, Maes M, Pereira IVA, da Silva TC, Govoni VM, Lopes VV, Crespo Yanguas S, Shestopalov VI, Nogueira MS, de Castro IA, Farhood A, Mannaerts I, van Grunsven L, Akakpo J, Lebofsky M, Jaeschke H, Cogliati B, Vinken M.

Biochim Biophys Acta. 2018 Mar;1864(3):819-830. doi: 10.1016/j.bbadis.2017.12.013. Epub 2017 Dec 12.


Effectiveness of low-dose diuretics for blood pressure reduction to optimal values in prehypertension: a randomized clinical trial.

Fuchs FD, Fuchs SC, Poli-de-Figueiredo CE, Figueiredo Neto JA, Scala LCN, Vilela-Martin JF, Moreira LB, Chaves H, Mota Gomes M, de Sousa MR, Silva RPE, Castro I, Cesarino EJ, Sousa ALL, Alves JG, Steffens AA, Brandão AA, Bortolotto LA, Afiune Neto A, Nóbrega AC, Franco RS, Sobral Filho DC, Nobre F, Schlatter R, Gus M, De David CN, Rafaelli L, Sesin GP, Berwanger O, Whelton PK.

J Hypertens. 2017 Dec 7. doi: 10.1097/HJH.0000000000001624. [Epub ahead of print]


Resistance exercise enhances oxygen uptake without worsening cardiac function in patients with systolic heart failure: a systematic review and meta-analysis.

Santos FV, Chiappa GR, Ramalho SHR, de Lima ACGB, de Souza FSJ, Cahalin LP, Durigan JLQ, de Castro I, Cipriano G Jr.

Heart Fail Rev. 2018 Jan;23(1):73-89. doi: 10.1007/s10741-017-9658-8. Review.


A Cluster Randomized Trial to Promote Healthy Menu Items for Children: The Kids' Choice Restaurant Program.

Ayala GX, Castro IA, Pickrel JL, Lin SF, Williams CB, Madanat H, Jun HJ, Zive M.

Int J Environ Res Public Health. 2017 Dec 1;14(12). pii: E1494. doi: 10.3390/ijerph14121494.


Identification of seipin-linked factors that act as determinants of a lipid droplet subpopulation.

Eisenberg-Bord M, Mari M, Weill U, Rosenfeld-Gur E, Moldavski O, Castro IG, Soni KG, Harpaz N, Levine TP, Futerman AH, Reggiori F, Bankaitis VA, Schuldiner M, Bohnert M.

J Cell Biol. 2018 Jan 2;217(1):269-282. doi: 10.1083/jcb.201704122. Epub 2017 Nov 29.


Quasi physisorptive two dimensional tungsten oxide nanosheets with extraordinary sensitivity and selectivity to NO2.

Khan H, Zavabeti A, Wang Y, Harrison CJ, Carey BJ, Mohiuddin M, Chrimes AF, De Castro IA, Zhang BY, Sabri YM, Bhargava SK, Ou JZ, Daeneke T, Russo SP, Li Y, Kalantar-Zadeh K.

Nanoscale. 2017 Dec 14;9(48):19162-19175. doi: 10.1039/c7nr05403c.


Management of the Complete Clinical Response.

Habr-Gama A, São Julião GP, Vailati BB, Castro I, Raffaele D.

Clin Colon Rectal Surg. 2017 Nov;30(5):387-394. doi: 10.1055/s-0037-1606116. Epub 2017 Nov 27. Review.


From TBT to booster biocides: Levels and impacts of antifouling along coastal areas of Panama.

Batista-Andrade JA, Caldas SS, Batista RM, Castro IB, Fillmann G, Primel EG.

Environ Pollut. 2018 Mar;234:243-252. doi: 10.1016/j.envpol.2017.11.063. Epub 2017 Nov 24.


Lpx1p links glucose-induced calcium signaling and plasma membrane H+-ATPase activation in Saccharomyces cerevisiae cells.

Castanheira DD, Santana EP, Godoy-Santos F, Diniz RHS, Faria-Oliveira F, Pereira RR, Trópia MJM, Castro IM, Brandão RL.

FEMS Yeast Res. 2018 Feb 1;18(1). doi: 10.1093/femsyr/fox088.


Genetic diversity and structure of Iberian Peninsula cowpeas compared to world-wide cowpea accessions using high density SNP markers.

Carvalho M, Muñoz-Amatriaín M, Castro I, Lino-Neto T, Matos M, Egea-Cortines M, Rosa E, Close T, Carnide V.

BMC Genomics. 2017 Nov 21;18(1):891. doi: 10.1186/s12864-017-4295-0.


Detection of schistosomiasis in an area directly affected by the São Francisco River large-scale water transposition project in the Northeast of Brazil.

Silva JDD Filho, Pinheiro MCC, Sousa MS, Gomes VDS, Castro IMN, Ramos AN Júnior, Bezerra FSM.

Rev Soc Bras Med Trop. 2017 Sep-Oct;50(5):658-665. doi: 10.1590/0037-8682-0299-2017.


Potential ecotoxicity of metals leached from antifouling paint particles under different salinities.

Soroldoni S, Martins SE, Castro IB, Pinho GLL.

Ecotoxicol Environ Saf. 2018 Feb;148:447-452. doi: 10.1016/j.ecoenv.2017.10.060. Epub 2017 Nov 6.


Sex differentiation in grayling (Salmonidae) goes through an all-male stage and is delayed in genetic males who instead grow faster.

Maitre D, Selmoni OM, Uppal A, Marques da Cunha L, Wilkins LGE, Roux J, Mobley KB, Castro I, Knörr S, Robinson-Rechavi M, Wedekind C.

Sci Rep. 2017 Nov 3;7(1):15024. doi: 10.1038/s41598-017-14905-9.


The molecular mechanism of Nystatin action is dependent on the membrane biophysical properties and lipid composition.

Dos Santos AG, Marquês JT, Carreira AC, Castro IR, Viana AS, Mingeot-Leclercq MP, de Almeida RFM, Silva LC.

Phys Chem Chem Phys. 2017 Nov 15;19(44):30078-30088. doi: 10.1039/c7cp05353c.


Who Is Influencing Whom? Latino Parent-Child Request Interactions and Product Purchases in Food Retail Environments.

Castro IA, Calderon J, Ayala GX.

Soc Mar Q. 2017 Jun;23(2):155-168. Epub 2017 Jan 5.


Laryngeal paracoccidioidomycosis presenting as solitary true vocal fold disease.

Eyer-Silva WA, Santana AC, Silva GARD, Azevedo MCVM, Barreto JLTMS, Neumann MA, Castro IJ, Basílio-de-Oliveira RP, Araujo LF, Ré NZ, Oliveira FM, Simas CJA, Sarvat MA, Ferry FRA.

IDCases. 2017 Sep 14;10:71-74. doi: 10.1016/j.idcr.2017.09.003. eCollection 2017.


Peroxisome Motility Measurement and Quantification Assay.

Metz J, Castro IG, Schrader M.

Bio Protoc. 2017 Sep 5;7(17). pii: e2536. doi: 10.21769/BioProtoc.2536.


Seven-year follow-up of the immune response after one or 2 doses of inactivated hepatitis A vaccine given at 1 year of age in the Mendoza Province of Argentina.

Espul C, Benedetti L, Linares M, Cuello H, Lo Castro I, Thollot Y, Rasuli A.

Hum Vaccin Immunother. 2017 Nov 2;13(11):2707-2712. doi: 10.1080/21645515.2017.1358326. Epub 2017 Sep 21.


Network of phosphatases and HDAC complexes at repressed chromatin.

de Castro IJ, Amin HA, Vinciotti V, Vagnarelli P.

Cell Cycle. 2017;16(21):2011-2017. doi: 10.1080/15384101.2017.1371883. Epub 2017 Sep 14.


Risk factors for the progression of chronic kidney disease after acute kidney injury.

Pereira BJ, Barreto S, Gentil T, Assis LS, Soeiro EM, Castro I, Laranja SM.

J Bras Nefrol. 2017 Jul-Sep;39(3):239-245. doi: 10.5935/0101-2800.20170041. Epub 2017 Aug 28. English, Portuguese.


Human gastric hyperinfection by Anisakis simplex: A severe and unusual presentation and a brief review.

Baptista-Fernandes T, Rodrigues M, Castro I, Paixão P, Pinto-Marques P, Roque L, Belo S, Ferreira PM, Mansinho K, Toscano C.

Int J Infect Dis. 2017 Nov;64:38-41. doi: 10.1016/j.ijid.2017.08.012. Epub 2017 Sep 4.


Non-antibiotic treatment for infectious diseases.

Ruiz J, Castro I, Calabuig E, Salavert M.

Rev Esp Quimioter. 2017 Sep;30 Suppl 1:66-71. Review.


Protection of echium oil by microencapsulation with phenolic compounds.

Comunian TA, Boillon MRG, Thomazini M, Nogueira MS, de Castro IA, Favaro-Trindade CS.

Food Res Int. 2016 Oct;88(Pt A):114-121. doi: 10.1016/j.foodres.2016.03.008. Epub 2016 Mar 9.


Exposure to fine particulate matter in the air alters placental structure and the renin-angiotensin system.

Soto SF, Melo JO, Marchesi GD, Lopes KL, Veras MM, Oliveira IB, Souza RM, de Castro I, Furukawa LNS, Saldiva PHN, Heimann JC.

PLoS One. 2017 Aug 18;12(8):e0183314. doi: 10.1371/journal.pone.0183314. eCollection 2017.


Molybdenum Oxides - From Fundamentals to Functionality.

de Castro IA, Datta RS, Ou JZ, Castellanos-Gomez A, Sriram S, Daeneke T, Kalantar-Zadeh K.

Adv Mater. 2017 Oct;29(40). doi: 10.1002/adma.201701619. Epub 2017 Aug 16. Review.


Epidemiological and clinical factors impact on the benefit of riluzole in the survival rates of patients with ALS.

Fávero FM, Voos MC, Castro I, Caromano FA, Oliveira ASB.

Arq Neuropsiquiatr. 2017 Aug;75(8):515-522. doi: 10.1590/0004-282X20170083. Erratum in: Arq Neuropsiquiatr. 2017 Sep;75(9):1.


Inhibition of connexin hemichannels alleviates non-alcoholic steatohepatitis in mice.

Willebrords J, Cogliati B, Pereira IVA, da Silva TC, Crespo Yanguas S, Maes M, Govoni VM, Lima A, Felisbino DA, Decrock E, Nogueira MS, de Castro IA, Leclercq I, Leybaert L, Rodrigues RM, Vinken M.

Sci Rep. 2017 Aug 15;7(1):8268. doi: 10.1038/s41598-017-08583-w.


A TIM-3 Oligonucleotide Aptamer Enhances T Cell Functions and Potentiates Tumor Immunity in Mice.

Gefen T, Castro I, Muharemagic D, Puplampu-Dove Y, Patel S, Gilboa E.

Mol Ther. 2017 Oct 4;25(10):2280-2288. doi: 10.1016/j.ymthe.2017.06.023. Epub 2017 Aug 8.


New lager brewery strains obtained by crossing techniques using cachaça (Brazilian spirit) yeasts.

Figueiredo BIC, Saraiva MAF, de Souza Pimenta PP, de Souza Testasicca MC, Sampaio GMS, da Cunha AC, Afonso LCC, Vieira de Queiroz M, Castro IM, Brandão RL.

Appl Environ Microbiol. 2017 Aug 4. pii: AEM.01582-17. doi: 10.1128/AEM.01582-17. [Epub ahead of print]


Obesity prevention and control: the urgent need for effective public policies.

Castro IRR.

Cad Saude Publica. 2017 Jul 27;33(7):e00100017. doi: 10.1590/0102-311X00100017. English, Portuguese, Spanish. No abstract available.


Thoracoabdominal asynchrony: Two methods in healthy, COPD, and interstitial lung disease patients.

Pereira MC, Porras DC, Lunardi AC, da Silva CCBM, Barbosa RCC, Cardenas LZ, Pletsch R, Ferreira JG, de Castro I, de Carvalho CRF, Caruso P, de Carvalho CRR, de Albuquerque ALP.

PLoS One. 2017 Aug 2;12(8):e0182417. doi: 10.1371/journal.pone.0182417. eCollection 2017.


Development of functional yogurt containing free and encapsulated echium oil, phytosterol and sinapic acid.

Comunian TA, Chaves IE, Thomazini M, Moraes ICF, Ferro-Furtado R, de Castro IA, Favaro-Trindade CS.

Food Chem. 2017 Dec 15;237:948-956. doi: 10.1016/j.foodchem.2017.06.071. Epub 2017 Jun 10.


Late onset multiple sclerosis: concerns in aging patients.

Lotti CBC, Oliveira ASB, Bichuetti DB, Castro I, Oliveira EML.

Arq Neuropsiquiatr. 2017 Jul;75(7):451-456. doi: 10.1590/0004-282X20170070.


Does laser phototherapy influence the proliferation of myoepithelial cells in the salivary gland of hypothyroid rats?

Uzêda-E-Silva VD, Rodriguez TT, Ramalho LMP, Xavier FCA, de Castro ICV, Pinheiro ALB, Dos Santos JN.

J Photochem Photobiol B. 2017 Aug;173:681-685. doi: 10.1016/j.jphotobiol.2017.07.008. Epub 2017 Jul 12.


Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques.

Martins MA, Shin YC, Gonzalez-Nieto L, Domingues A, Gutman MJ, Maxwell HS, Castro I, Magnani DM, Ricciardi M, Pedreño-Lopez N, Bailey V, Betancourt D, Altman JD, Pauthner M, Burton DR, von Bredow B, Evans DT, Yuan M, Parks CL, Ejima K, Allison DB, Rakasz E, Barber GN, Capuano S 3rd, Lifson JD, Desrosiers RC, Watkins DI.

PLoS Pathog. 2017 Jul 21;13(7):e1006529. doi: 10.1371/journal.ppat.1006529. eCollection 2017 Jul.


Simian T Lymphotropic Virus 1 Infection of Papio anubis: tax Sequence Heterogeneity and T Cell Recognition.

Termini JM, Magnani DM, Maxwell HS, Lauer W, Castro I, Pecotte J, Barber GN, Watkins DI, Desrosiers RC.

J Virol. 2017 Sep 27;91(20). pii: e00950-17. doi: 10.1128/JVI.00950-17. Print 2017 Oct 15.


Polymorphisms of the TNF-α gene interact with plasma fatty acids on inflammatory biomarker profile: a population-based, cross-sectional study in São Paulo, Brazil.

Oki E, Norde MN, Carioca AAF, Souza JMP, Castro IA, Marchioni DML, Fisberg RM, Rogero MM.

Br J Nutr. 2017 Jun;117(12):1663-1673. doi: 10.1017/S0007114517001416. Epub 2017 Jun 21.


<i>Ituglanis compactus</i>, a new species of catfish (Siluriformes: Trichomycteridae) from the rio Jari drainage, lower Amazon, Brazil.

Castro ÍDS, Wosiacki WB.

Zootaxa. 2017 Mar 19;4244(2):207-218. doi: 10.11646/zootaxa.4244.2.3.


Enterocytozoon bieneusi detected by molecular methods in raw sewage and treated effluent from a combined system in Brazil.

Yamashiro S, Fiuza VRDS, Teixeira ÂTLS, Branco N, Levy CE, Castro ICVS, Franco RMB.

Mem Inst Oswaldo Cruz. 2017 Jun;112(6):403-410. doi: 10.1590/0074-02760160435.


Reversible solvatomagnetic switching in a single-ion magnet from an entatic state.

Vallejo J, Pardo E, Viciano-Chumillas M, Castro I, Amorós P, Déniz M, Ruiz-Pérez C, Yuste-Vivas C, Krzystek J, Julve M, Lloret F, Cano J.

Chem Sci. 2017 May 1;8(5):3694-3702. doi: 10.1039/c6sc05188j. Epub 2017 Feb 13.


Spontaneous variation regarding grape berry skin color: A comprehensive study of berry development by means of biochemical and molecular markers.

Ferreira V, Fernandes F, Carrasco D, Hernandez MG, Pinto-Carnide O, Arroyo-García R, Andrade P, Valentão P, Falco V, Castro I.

Food Res Int. 2017 Jul;97:149-161. doi: 10.1016/j.foodres.2017.03.050. Epub 2017 Apr 1.


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