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Items: 31

1.

The skeletal phenotype of achondrogenesis type 1A is caused exclusively by cartilage defects.

Bird IM, Kim SH, Schweppe DK, Caetano-Lopes J, Robling AG, Charles JF, Gygi SP, Warman ML, Smits PJ.

Development. 2018 Jan 8;145(1). pii: dev156588. doi: 10.1242/dev.156588.

2.

Methotrexate and low-dose prednisolone downregulate osteoclast function by decreasing receptor activator of nuclear factor-κβ expression in monocytes from patients with early rheumatoid arthritis.

Perpétuo IP, Caetano-Lopes J, Rodrigues AM, Campanilho-Marques R, Ponte C, Canhão H, Ainola M, Fonseca JE.

RMD Open. 2017 Jul 13;3(1):e000365. doi: 10.1136/rmdopen-2016-000365. eCollection 2017.

3.

Clcn7F318L/+ as a new mouse model of Albers-Schönberg disease.

Caetano-Lopes J, Lessard SG, Hann S, Espinoza K, Kang KS, Lim KE, Horan DJ, Noonan HR, Hu D, Baron R, Robling AG, Warman ML.

Bone. 2017 Dec;105:253-261. doi: 10.1016/j.bone.2017.09.007. Epub 2017 Sep 20.

PMID:
28942122
4.

Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery.

Rees HA, Komor AC, Yeh WH, Caetano-Lopes J, Warman M, Edge ASB, Liu DR.

Nat Commun. 2017 Jun 6;8:15790. doi: 10.1038/ncomms15790.

5.

Corrigendum: Ankylosing Spondylitis Patients Have Impaired Osteoclast Gene Expression in Circulating Osteoclast Precursors.

Perpétuo IP, Caetano-Lopes J, Vieira-Sousa E, Campanilho-Marques R, Ponte C, Khmelinskii N, Canhão H, Ainola M, Fonseca JE.

Front Med (Lausanne). 2017 Apr 12;4:38. doi: 10.3389/fmed.2017.00038. eCollection 2017.

6.

Effect of Tumor Necrosis Factor Inhibitor Therapy on Osteoclasts Precursors in Rheumatoid Arthritis.

Perpétuo IP, Caetano-Lopes J, Rodrigues AM, Campanilho-Marques R, Ponte C, Canhão H, Ainola M, Fonseca JE.

Biomed Res Int. 2017;2017:2690402. doi: 10.1155/2017/2690402. Epub 2017 Feb 13.

7.

Ankylosing Spondylitis Patients Have Impaired Osteoclast Gene Expression in Circulating Osteoclast Precursors.

Perpétuo IP, Caetano-Lopes J, Vieira-Sousa E, Campanilho-Marques R, Ponte C, Canhão H, Ainola M, Fonseca JE.

Front Med (Lausanne). 2017 Jan 27;4:5. doi: 10.3389/fmed.2017.00005. eCollection 2017. Erratum in: Front Med (Lausanne). 2017 Apr 12;4:38.

8.

Effect of Tumor Necrosis Factor Inhibitor Therapy on Osteoclasts Precursors in Ankylosing Spondylitis.

Perpétuo IP, Raposeiro R, Caetano-Lopes J, Vieira-Sousa E, Campanilho-Marques R, Ponte C, Canhão H, Ainola M, Fonseca JE.

PLoS One. 2015 Dec 16;10(12):e0144655. doi: 10.1371/journal.pone.0144655. eCollection 2015.

9.

At the moment of occurrence of a fragility hip fracture, men have higher mechanical properties values in comparison with women.

Vale AC, Aleixo IP, Lúcio M, Saraiva A, Caetano-Lopes J, Rodrigues A, Amaral PM, Rosa LG, Monteiro J, Fonseca JE, Vaz MF, Canhão H.

BMC Musculoskelet Disord. 2013 Oct 16;14:295. doi: 10.1186/1471-2474-14-295.

10.

Bone histomorphometry revisited.

Vidal B, Pinto A, Galvão MJ, Santos AR, Rodrigues A, Cascão R, Abdulghani S, Caetano-Lopes J, Ferreira A, Fonseca JE, Canhao H.

Acta Reumatol Port. 2012 Oct-Dec;37(4):294-300. Review.

11.

Protective effect of an ERAP1 haplotype in ankylosing spondylitis: investigating non-MHC genes in HLA-B27-positive individuals.

Bettencourt BF, Rocha FL, Alves H, Amorim R, Caetano-Lopes J, Vieira-Sousa E, Pimentel-Santos F, Lima M, Porto G, Branco JC, Fonseca JE, Bruges-Armas J.

Rheumatology (Oxford). 2013 Dec;52(12):2168-76. doi: 10.1093/rheumatology/ket269. Epub 2013 Sep 17.

PMID:
24046467
12.

Rheumatoid arthritis bone fragility is associated with upregulation of IL17 and DKK1 gene expression.

Caetano-Lopes J, Rodrigues A, Lopes A, Vale AC, Pitts-Kiefer MA, Vidal B, Perpétuo IP, Monteiro J, Konttinen YT, Vaz MF, Nazarian A, Canhão H, Fonseca JE.

Clin Rev Allergy Immunol. 2014 Aug;47(1):38-45. doi: 10.1007/s12016-013-8366-y.

PMID:
23546988
13.

Low osteocalcin/collagen type I bone gene expression ratio is associated with hip fragility fractures.

Rodrigues AM, Caetano-Lopes J, Vale AC, Vidal B, Lopes A, Aleixo I, Polido-Pereira J, Sepriano A, Perpétuo IP, Monteiro J, Vaz MF, Fonseca JE, Canhão H.

Bone. 2012 Dec;51(6):981-9. doi: 10.1016/j.bone.2012.08.129. Epub 2012 Sep 5.

PMID:
22975110
14.

Smoking is a predictor of worse trabecular mechanical performance in hip fragility fracture patients.

Rodrigues AM, Caetano-Lopes J, Vale AC, Aleixo I, Pena AS, Faustino A, Sepriano A, Polido-Pereira J, Vieira-Sousa E, Lucas R, Romeu JC, Monteiro J, Vaz MF, Fonseca JE, Canhão H.

J Bone Miner Metab. 2012 Nov;30(6):692-9. doi: 10.1007/s00774-012-0370-4. Epub 2012 Aug 14.

PMID:
22886402
15.

TNF promoter -308 G>A and LTA 252 A>G polymorphisms in Portuguese patients with systemic lupus erythematosus.

Santos MJ, Carmona-Fernandes D, Caetano-Lopes J, Perpétuo IP, Vidal B, Capela S, Canas da Silva J, Fonseca JE.

Rheumatol Int. 2012 Aug;32(8):2239-44. doi: 10.1007/s00296-011-1950-7. Epub 2011 May 5.

PMID:
21544635
16.

Lymphotoxin-α 252 A>G polymorphism: a link between disease susceptibility and dyslipidemia in rheumatoid arthritis?

Santos MJ, Fernandes D, Caetano-Lopes J, Perpetuo IP, Vidal B, Canhao H, Fonseca JE.

J Rheumatol. 2011 Jul;38(7):1244-9. doi: 10.3899/jrheum.101170. Epub 2011 Apr 1.

PMID:
21459939
17.

Upregulation of inflammatory genes and downregulation of sclerostin gene expression are key elements in the early phase of fragility fracture healing.

Caetano-Lopes J, Lopes A, Rodrigues A, Fernandes D, Perpétuo IP, Monjardino T, Lucas R, Monteiro J, Konttinen YT, Canhão H, Fonseca JE.

PLoS One. 2011 Feb 11;6(2):e16947. doi: 10.1371/journal.pone.0016947.

18.

Alterations on peripheral blood B-cell subpopulations in very early arthritis patients.

Moura RA, Weinmann P, Pereira PA, Caetano-Lopes J, Canhão H, Sousa E, Mourão AF, Rodrigues AM, Queiroz MV, Souto-Carneiro MM, Graça L, Fonseca JE.

Rheumatology (Oxford). 2010 Jun;49(6):1082-92. doi: 10.1093/rheumatology/keq029. Epub 2010 Mar 7.

PMID:
20211867
19.

Chronic arthritis leads to disturbances in the bone collagen network.

Caetano-Lopes J, Nery AM, Canhão H, Duarte J, Cascão R, Rodrigues A, Perpétuo IP, Abdulghani S, Amaral PM, Sakaguchi S, Konttinen YT, Graça L, Vaz MF, Fonseca JE.

Arthritis Res Ther. 2010;12(1):R9. doi: 10.1186/ar2908. Epub 2010 Jan 15.

20.

An analysis of joint replacement in patients with systemic lupus erythematosus.

Mourão AF, Amaral M, Caetano-Lopes J, Isenberg D.

Lupus. 2009 Dec;18(14):1298-302. doi: 10.1177/0961203309345795. Epub 2009 Oct 22.

PMID:
19850657
21.

Evaluation of bone mechanical strenght and fracture risk assessment (Frax) in patients with hip joint replacement surgery.

Rodrigues A, Caetano-Lopes J, Nery A, Sousa E, Polido-Pereira J, Vale M, Amaral P, Romeu JC, Viana Queiroz M, Monteiro J, Vaz MF, Fonseca JE, Canhão H.

Acta Reumatol Port. 2009 Jul-Sep;34(3):504-10.

22.

Ankylosing spondylitis susceptibility and severity--contribution of TNF gene promoter polymorphisms at positions -238 and -308.

Sousa E, Caetano-Lopes J, Pinto P, Pimentel F, Teles J, Canhão H, Rodrigues A, Resende C, Mourão AF, Ribeiro C, Pinto TL, Rosa CM, da Silva JA, Branco J, Ventura F, Queiroz MV, Fonseca JE.

Ann N Y Acad Sci. 2009 Sep;1173:581-8. doi: 10.1111/j.1749-6632.2009.04758.x.

PMID:
19758203
23.

Chronic arthritis directly induces quantitative and qualitative bone disturbances leading to compromised biomechanical properties.

Caetano-Lopes J, Nery AM, Henriques R, Canhão H, Duarte J, Amaral PM, Vale M, Moura RA, Pereira PA, Weinmann P, Abdulghani S, Souto-Carneiro M, Rego P, Monteiro J, Sakagushi S, Queiroz MV, Konttinen YT, Graça L, Vaz MF, Fonseca JE.

Clin Exp Rheumatol. 2009 May-Jun;27(3):475-82.

PMID:
19604441
24.

[Juvenile dermatomyositis associated with anasarca - a clinical case].

Mourão AF, Pinto TL, Falcão S, Ribeiro C, Vieira H, Caetano-Lopes J, Nero P, dos Santos FP, Guimarães J, Branco JC.

Acta Reumatol Port. 2009 Apr-Jun;34(2A):276-80. Portuguese.

25.

Biomechanical effects of inflammatory diseases on bone-rheumatoid arthritis as a paradigm.

Abdulghani S, Caetano-Lopes J, Canhão H, Fonseca JE.

Autoimmun Rev. 2009 Jul;8(8):668-71. doi: 10.1016/j.autrev.2009.02.021. Epub 2009 Feb 15. Review.

PMID:
19223022
26.

Tumor necrosis factor-alpha -308 genotypes influence inflammatory activity and TNF-alpha serum concentrations in children with juvenile idiopathic arthritis.

Mourão AF, Caetano-Lopes J, Costa P, Canhão H, Santos MJ, Pinto P, Brito I, Nicola P, Cavaleiro J, Teles J, Sousa A, Gomes JM, Branco J, da Costa JT, Pedro JG, de Queiroz MV, Fonseca JE.

J Rheumatol. 2009 Apr;36(4):837-42. doi: 10.3899/jrheum.080615. Epub 2009 Jan 22. Erratum in: J Rheumatol. 2009 May;36(5):1091.

PMID:
19208590
27.

Osteoimmunology--the hidden immune regulation of bone.

Caetano-Lopes J, Canhão H, Fonseca JE.

Autoimmun Rev. 2009 Jan;8(3):250-5. doi: 10.1016/j.autrev.2008.07.038. Epub 2008 Aug 21. Review.

PMID:
18722561
28.

Delayed neutrophil apoptosis in very early rheumatoid arthritis patients is abrogated by methotrexate therapy.

Weinmann P, Moura RA, Caetano-Lopes JR, Pereira PA, Canhão H, Queiroz MV, Fonseca JE.

Clin Exp Rheumatol. 2007 Nov-Dec;25(6):885-7.

PMID:
18173925
29.

Assessment of laboratory measurements and -308 TNFalpha gene promoter polymorphisms in normal bone mineral density.

Canhao H, Fonseca JE, Caetano-Lopes J, Saldanha C, Queiroz MV.

Clin Rheumatol. 2008 Mar;27(3):301-7. Epub 2007 Aug 8.

PMID:
17684700
30.

Osteoblasts and bone formation.

Caetano-Lopes J, Canhão H, Fonseca JE.

Acta Reumatol Port. 2007 Apr-Jun;32(2):103-10. Review.

31.

Contribution for new genetic markers of rheumatoid arthritis activity and severity: sequencing of the tumor necrosis factor-alpha gene promoter.

Fonseca JE, Cavaleiro J, Teles J, Sousa E, Andreozzi VL, Antunes M, Amaral-Turkman MA, Canhão H, Mourão AF, Lopes J, Caetano-Lopes J, Weinmann P, Sobral M, Nero P, Saavedra MJ, Malcata A, Cruz M, Melo R, Braña A, Miranda L, Patto JV, Barcelos A, da Silva JC, Santos LM, Figueiredo G, Rodrigues M, Jesus H, Quintal A, Carvalho T, da Silva JA, Branco J, Queiroz MV.

Arthritis Res Ther. 2007;9(2):R37.

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