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Items: 1 to 50 of 423

1.

Insights into inflammatory priming of mesenchymal stromal cells: functional biological impacts.

Najar M, Krayem M, Merimi M, Burny A, Meuleman N, Bron D, Raicevic G, Lagneaux L.

Inflamm Res. 2018 Jan 23. doi: 10.1007/s00011-018-1131-1. [Epub ahead of print] Review.

PMID:
29362849
2.

Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality.

Artesi M, Marçais A, Durkin K, Rosewick N, Hahaut V, Suarez F, Trinquand A, Lhermitte L, Asnafi V, Avettand-Fenoel V, Burny A, Georges M, Hermine O, Van den Broeke A.

Leukemia. 2017 Nov;31(11):2532-2535. doi: 10.1038/leu.2017.260. Epub 2017 Aug 16. No abstract available.

3.

Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis.

Rosewick N, Durkin K, Artesi M, Marçais A, Hahaut V, Griebel P, Arsic N, Avettand-Fenoel V, Burny A, Charlier C, Hermine O, Georges M, Van den Broeke A.

Nat Commun. 2017 May 23;8:15264. doi: 10.1038/ncomms15264.

4.

Repression of Human T-lymphotropic virus type 1 Long Terminal Repeat sense transcription by Sp1 recruitment to novel Sp1 binding sites.

Fauquenoy S, Robette G, Kula A, Vanhulle C, Bouchat S, Delacourt N, Rodari A, Marban C, Schwartz C, Burny A, Rohr O, Van Driessche B, Van Lint C.

Sci Rep. 2017 Mar 3;7:43221. doi: 10.1038/srep43221.

5.

Characterization of new RNA polymerase III and RNA polymerase II transcriptional promoters in the Bovine Leukemia Virus genome.

Van Driessche B, Rodari A, Delacourt N, Fauquenoy S, Vanhulle C, Burny A, Rohr O, Van Lint C.

Sci Rep. 2016 Aug 22;6:31125. doi: 10.1038/srep31125.

6.

Characterization of novel Bovine Leukemia Virus (BLV) antisense transcripts by deep sequencing reveals constitutive expression in tumors and transcriptional interaction with viral microRNAs.

Durkin K, Rosewick N, Artesi M, Hahaut V, Griebel P, Arsic N, Burny A, Georges M, Van den Broeke A.

Retrovirology. 2016 May 3;13(1):33. doi: 10.1186/s12977-016-0267-8.

7.

An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression.

Darcis G, Kula A, Bouchat S, Fujinaga K, Corazza F, Ait-Ammar A, Delacourt N, Melard A, Kabeya K, Vanhulle C, Van Driessche B, Gatot JS, Cherrier T, Pianowski LF, Gama L, Schwartz C, Vila J, Burny A, Clumeck N, Moutschen M, De Wit S, Peterlin BM, Rouzioux C, Rohr O, Van Lint C.

PLoS Pathog. 2015 Jul 30;11(7):e1005063. doi: 10.1371/journal.ppat.1005063. eCollection 2015 Jul.

8.

NFAT-1, Sp-1, Sp-3, and miR-21: New regulators of chemokine C receptor 7 expression in mature human dendritic cells.

Al Akoum C, Akl I, Rouas R, Fayyad-Kazan M, Falha L, Renno T, Burny A, Lewalle P, Fayyad-Kazan H, Badran B.

Hum Immunol. 2015 May;76(5):307-17. doi: 10.1016/j.humimm.2015.03.010. Epub 2015 Mar 19.

PMID:
25797200
9.

A microRNA profile of human CD8(+) regulatory T cells and characterization of the effects of microRNAs on Treg cell-associated genes.

Jebbawi F, Fayyad-Kazan H, Merimi M, Lewalle P, Verougstraete JC, Leo O, Romero P, Burny A, Badran B, Martiat P, Rouas R.

J Transl Med. 2014 Aug 6;12:218. doi: 10.1186/s12967-014-0218-x.

10.

Vaccination against δ-retroviruses: the bovine leukemia virus paradigm.

Gutiérrez G, Rodríguez SM, de Brogniez A, Gillet N, Golime R, Burny A, Jaworski JP, Alvarez I, Vagnoni L, Trono K, Willems L.

Viruses. 2014 Jun 20;6(6):2416-27. doi: 10.3390/v6062416. Review.

11.

Downregulation of microRNA-24 and -181 parallels the upregulation of IFN-γ secreted by activated human CD4 lymphocytes.

Fayyad-Kazan H, Hamade E, Rouas R, Najar M, Fayyad-Kazan M, El Zein N, ElDirani R, Hussein N, Fakhry M, Al-Akoum C, Burny A, Martiat P, Badran B.

Hum Immunol. 2014 Jul;75(7):677-85. doi: 10.1016/j.humimm.2014.01.007. Epub 2014 Apr 3.

PMID:
24704866
12.

Circulating miR-150 and miR-342 in plasma are novel potential biomarkers for acute myeloid leukemia.

Fayyad-Kazan H, Bitar N, Najar M, Lewalle P, Fayyad-Kazan M, Badran R, Hamade E, Daher A, Hussein N, ElDirani R, Berri F, Vanhamme L, Burny A, Martiat P, Rouas R, Badran B.

J Transl Med. 2013 Feb 7;11:31. doi: 10.1186/1479-5876-11-31.

13.

Deep sequencing reveals abundant noncanonical retroviral microRNAs in B-cell leukemia/lymphoma.

Rosewick N, Momont M, Durkin K, Takeda H, Caiment F, Cleuter Y, Vernin C, Mortreux F, Wattel E, Burny A, Georges M, Van den Broeke A.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2306-11. doi: 10.1073/pnas.1213842110. Epub 2013 Jan 23.

14.

Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses.

Simonis N, Rual JF, Lemmens I, Boxus M, Hirozane-Kishikawa T, Gatot JS, Dricot A, Hao T, Vertommen D, Legros S, Daakour S, Klitgord N, Martin M, Willaert JF, Dequiedt F, Navratil V, Cusick ME, Burny A, Van Lint C, Hill DE, Tavernier J, Kettmann R, Vidal M, Twizere JC.

Retrovirology. 2012 Mar 29;9:26. doi: 10.1186/1742-4690-9-26.

15.

MicroRNA profile of circulating CD4-positive regulatory T cells in human adults and impact of differentially expressed microRNAs on expression of two genes essential to their function.

Fayyad-Kazan H, Rouas R, Fayyad-Kazan M, Badran R, El Zein N, Lewalle P, Najar M, Hamade E, Jebbawi F, Merimi M, Romero P, Burny A, Badran B, Martiat P.

J Biol Chem. 2012 Mar 23;287(13):9910-22. doi: 10.1074/jbc.M111.337154. Epub 2012 Jan 31. Erratum in: J Biol Chem. 2012 May 25;287(22):18584.

16.

IFN-α and CD46 stimulation are associated with active lupus and skew natural T regulatory cell differentiation to type 1 regulatory T (Tr1) cells.

Le Buanec H, Gougeon ML, Mathian A, Lebon P, Dupont JM, Peltre G, Hemon P, Schmid M, Bizzini B, Künding T, Burny A, Bensussan A, Amoura Z, Gallo RC, Zagury D.

Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):18995-9000. doi: 10.1073/pnas.1113301108. Epub 2011 Nov 7.

17.

Chromatin disruption in the promoter of bovine leukemia virus during transcriptional activation.

Colin L, Dekoninck A, Reichert M, Calao M, Merimi M, Van den Broeke A, Vierendeel V, Cleuter Y, Burny A, Rohr O, Van Lint C.

Nucleic Acids Res. 2011 Dec;39(22):9559-73. doi: 10.1093/nar/gkr671. Epub 2011 Sep 2.

18.

The AP-1 binding sites located in the pol gene intragenic regulatory region of HIV-1 are important for viral replication.

Colin L, Vandenhoudt N, de Walque S, Van Driessche B, Bergamaschi A, Martinelli V, Cherrier T, Vanhulle C, Guiguen A, David A, Burny A, Herbein G, Pancino G, Rohr O, Van Lint C.

PLoS One. 2011 Apr 19;6(4):e19084. doi: 10.1371/journal.pone.0019084.

19.

Correction: Valproate treatment of human cord blood CD4-positive effector T cells confers on them the molecular profile (microRNA signature and FOXP3 expression) of natural regulatory CD4-positive cells through inhibition of histone deacetylase.

Fayyad-Kazan H, Rouas R, Merimi M, El Zein N, Lewalle P, Jebbawi F, Mourtada M, Badran H, Ezzeddine M, Salaun B, Romero P, Burny AS, Martiat P, Badran B.

J Biol Chem. 2011 Feb 18;286(7):5934. doi: 10.1074/jbc.A110.119628. No abstract available.

20.

Kinoids: a family of immunogens for active anticytokine immunotherapy applied to autoimmune diseases and cancer.

Bizzini B, Drouet B, Zagury D, Abitbol M, Burny A, Boissier MC.

Immunotherapy. 2010 May;2(3):347-65. doi: 10.2217/imt.10.16. Review.

PMID:
20635900
21.

Cytotoxic responses to BLV tax oncoprotein do not prevent leukemogenesis in sheep.

Van den Broeke A, Oumouna M, Beskorwayne T, Szynal M, Cleuter Y, Babiuk S, Bagnis C, Martiat P, Burny A, Griebel P.

Leuk Res. 2010 Dec;34(12):1663-9. doi: 10.1016/j.leukres.2010.06.003. Epub 2010 Jun 29.

PMID:
20591480
22.

Preclinical evidence for a beneficial impact of valproate on the response of small cell lung cancer to first-line chemotherapy.

Hubaux R, Vandermeers F, Crisanti MC, Kapoor V, Burny A, Mascaux C, Albelda SM, Willems L.

Eur J Cancer. 2010 Jun;46(9):1724-34. doi: 10.1016/j.ejca.2010.03.021. Epub 2010 May 5. Erratum in: Eur J Cancer. 2010 Nov;46(17):3127. Crisanti, Cecilia [corrected to Crisanti, M Cecilia].

PMID:
20451370
23.

Valproate treatment of human cord blood CD4-positive effector T cells confers on them the molecular profile (microRNA signature and FOXP3 expression) of natural regulatory CD4-positive cells through inhibition of histone deacetylase.

Fayyad-Kazan H, Rouas R, Merimi M, El Zein N, Lewalle P, Jebbawi F, Mourtada M, Badran H, Ezzeddine M, Salaun B, Romero P, Burny A, Martiat P, Badran B.

J Biol Chem. 2010 Jul 2;285(27):20481-91. doi: 10.1074/jbc.M110.119628. Epub 2010 Apr 28. Erratum in: J Biol Chem. 2011 Feb 18;286(7):5934. J Biol Chem. ;286(7):5934.

24.

DNA cytosine methylation in the bovine leukemia virus promoter is associated with latency in a lymphoma-derived B-cell line: potential involvement of direct inhibition of cAMP-responsive element (CRE)-binding protein/CRE modulator/activation transcription factor binding.

Pierard V, Guiguen A, Colin L, Wijmeersch G, Vanhulle C, Van Driessche B, Dekoninck A, Blazkova J, Cardona C, Merimi M, Vierendeel V, Calomme C, Nguyên TL, Nuttinck M, Twizere JC, Kettmann R, Portetelle D, Burny A, Hirsch I, Rohr O, Van Lint C.

J Biol Chem. 2010 Jun 18;285(25):19434-49. doi: 10.1074/jbc.M110.107607. Epub 2010 Apr 22.

25.

Earlier onset of delta-retrovirus-induced leukemia after splenectomy.

Florins A, Reichert M, Asquith B, Bouzar AB, Jean G, François C, Jasik A, Burny A, Kettmann R, Willems L.

PLoS One. 2009 Sep 14;4(9):e6943. doi: 10.1371/journal.pone.0006943.

26.

Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection.

Reuse S, Calao M, Kabeya K, Guiguen A, Gatot JS, Quivy V, Vanhulle C, Lamine A, Vaira D, Demonte D, Martinelli V, Veithen E, Cherrier T, Avettand V, Poutrel S, Piette J, de Launoit Y, Moutschen M, Burny A, Rouzioux C, De Wit S, Herbein G, Rohr O, Collette Y, Lambotte O, Clumeck N, Van Lint C.

PLoS One. 2009 Jun 30;4(6):e6093. doi: 10.1371/journal.pone.0006093.

27.

Gene activation therapy: from the BLV model to HAM/TSP patients.

Lezin A, Olindo S, Belrose G, Signate A, Cesaire R, Smadja D, Macallan D, Asquith B, Bangham C, Bouzar A, Gillet N, Defoiche J, Florins A, Verlaeten O, Burny A, Willems L.

Front Biosci (Schol Ed). 2009 Jun 1;1:205-15. Review.

PMID:
19482696
28.

Epigenetics and leukemia: unraveling oncogenic processes in the BLV ovine model.

Merimi M, Ozkan Y, Cleuter Y, Griebel P, Burny A, Martiat P, Van den Broeke A.

Front Biosci (Schol Ed). 2009 Jun 1;1:154-63. Review.

PMID:
19482691
29.

Human natural Treg microRNA signature: role of microRNA-31 and microRNA-21 in FOXP3 expression.

Rouas R, Fayyad-Kazan H, El Zein N, Lewalle P, Rothé F, Simion A, Akl H, Mourtada M, El Rifai M, Burny A, Romero P, Martiat P, Badran B.

Eur J Immunol. 2009 Jun;39(6):1608-18. doi: 10.1002/eji.200838509.

30.

Valproate, in combination with pemetrexed and cisplatin, provides additional efficacy to the treatment of malignant mesothelioma.

Vandermeers F, Hubert P, Delvenne P, Mascaux C, Grigoriu B, Burny A, Scherpereel A, Willems L.

Clin Cancer Res. 2009 Apr 15;15(8):2818-28. doi: 10.1158/1078-0432.CCR-08-1579. Epub 2009 Apr 7.

31.

Deregulation of calcium fluxes in HTLV-I infected CD4-positive T-cells plays a major role in malignant transformation.

Akl H, Badran B, El Zein N, Dobirta G, Burny A, Martiat P.

Front Biosci (Landmark Ed). 2009 Jan 1;14:3925-34. Review.

PMID:
19273323
32.

Acetylation of the human T-cell leukemia virus type 1 Tax oncoprotein by p300 promotes activation of the NF-kappaB pathway.

Lodewick J, Lamsoul I, Polania A, Lebrun S, Burny A, Ratner L, Bex F.

Virology. 2009 Mar 30;386(1):68-78. doi: 10.1016/j.virol.2008.12.043. Epub 2009 Feb 5.

33.

Unsung hero Robert C. Gallo.

Abbadessa G, Accolla R, Aiuti F, Albini A, Aldovini A, Alfano M, Antonelli G, Bartholomew C, Bentwich Z, Bertazzoni U, Berzofsky JA, Biberfeld P, Boeri E, Buonaguro L, Buonaguro FM, Bukrinsky M, Burny A, Caruso A, Cassol S, Chandra P, Ceccherini-Nelli L, Chieco-Bianchi L, Clerici M, Colombini-Hatch S, de Giuli Morghen C, de Maria A, de Rossi A, Dierich M, Della-Favera R, Dolei A, Douek D, Erfle V, Felber B, Fiorentini S, Franchini G, Gershoni JM, Gotch F, Green P, Greene WC, Hall W, Haseltine W, Jacobson S, Kallings LO, Kalyanaraman VS, Katinger H, Khalili K, Klein G, Klein E, Klotman M, Klotman P, Kotler M, Kurth R, Lafeuillade A, La Placa M, Lewis J, Lillo F, Lisziewicz J, Lomonico A, Lopalco L, Lori F, Lusso P, Macchi B, Malim M, Margolis L, Markham PD, McClure M, Miller N, Mingari MC, Moretta L, Noonan D, O'Brien S, Okamoto T, Pal R, Palese P, Panet A, Pantaleo G, Pavlakis G, Pistello M, Plotkin S, Poli G, Pomerantz R, Radaelli A, Robertguroff M, Roederer M, Sarngadharan MG, Schols D, Secchiero P, Shearer G, Siccardi A, Stevenson M, Svoboda J, Tartaglia J, Torelli G, Tornesello ML, Tschachler E, Vaccarezza M, Vallbracht A, van Lunzen J, Varnier O, Vicenzi E, von Melchner H, Witz I, Zagury D, Zagury JF, Zauli G, Zipeto D.

Science. 2009 Jan 9;323(5911):206-7. doi: 10.1126/science.323.5911.206. No abstract available.

PMID:
19131607
34.

Evolution of microRNA expression during human bronchial squamous carcinogenesis.

Mascaux C, Laes JF, Anthoine G, Haller A, Ninane V, Burny A, Sculier JP.

Eur Respir J. 2009 Feb;33(2):352-9. doi: 10.1183/09031936.00084108. Epub 2008 Nov 14.

35.

Valproate synergizes with purine nucleoside analogues to induce apoptosis of B-chronic lymphocytic leukaemia cells.

Bouzar AB, Boxus M, Defoiche J, Berchem G, Macallan D, Pettengell R, Willis F, Burny A, Lagneaux L, Bron D, Chatelain B, Chatelain C, Willems L.

Br J Haematol. 2009 Jan;144(1):41-52. doi: 10.1111/j.1365-2141.2008.07426.x. Epub 2008 Nov 1.

PMID:
19006566
36.

Reduction of B cell turnover in chronic lymphocytic leukaemia.

Defoiche J, Debacq C, Asquith B, Zhang Y, Burny A, Bron D, Lagneaux L, Macallan D, Willems L.

Br J Haematol. 2008 Oct;143(2):240-7. doi: 10.1111/j.1365-2141.2008.07348.x. Epub 2008 Aug 15.

PMID:
18710389
37.

A pervasive role of histone acetyltransferases and deacetylases in an NF-kappaB-signaling code.

Calao M, Burny A, Quivy V, Dekoninck A, Van Lint C.

Trends Biochem Sci. 2008 Jul;33(7):339-49. doi: 10.1016/j.tibs.2008.04.015. Epub 2008 Jun 26. Review.

PMID:
18585916
38.

Emphasis on cell turnover in two hosts infected by bovine leukemia virus: a rationale for host susceptibility to disease.

Florins A, Boxus M, Vandermeers F, Verlaeten O, Bouzar AB, Defoiche J, Hubaux R, Burny A, Kettmann R, Willems L.

Vet Immunol Immunopathol. 2008 Sep 15;125(1-2):1-7. doi: 10.1016/j.vetimm.2008.04.007. Epub 2008 Apr 16. Review.

PMID:
18513803
39.

The role of NPM, p14arf and MDM2 in precursors of bronchial squamous cell carcinoma.

Mascaux C, Bex F, Martin B, Burny A, Haller A, Paesmans M, Willard-Gallo K, Ninane V, Sculier JP.

Eur Respir J. 2008 Sep;32(3):678-86. doi: 10.1183/09031936.00008408. Epub 2008 May 14.

40.

[Cancer research in the French speaking community in Belgium].

Burny A.

Bull Cancer. 2008 Mar;95(3):269-70. French.

41.

Progressive loss of CD3 expression after HTLV-I infection results from chromatin remodeling affecting all the CD3 genes and persists despite early viral genes silencing.

Akl H, Badran B, Dobirta G, Manfouo-Foutsop G, Moschitta M, Merimi M, Burny A, Martiat P, Willard-Gallo KE.

Virol J. 2007 Sep 6;4:85.

42.

Control of allergic reactions in mice by an active anti-murine IL-4 immunization.

Le Buanec H, Paturance S, Couillin I, Schnyder-Candrian S, Larcier P, Ryffel B, Bizzini B, Bensussan A, Burny A, Gallo R, Zagury D, Peltre G.

Vaccine. 2007 Oct 10;25(41):7206-16. Epub 2007 Aug 3.

PMID:
17719148
43.

Histone deacetylase mediated transcriptional activation reduces proviral loads in HTLV-1 associated myelopathy/tropical spastic paraparesis patients.

Lezin A, Gillet N, Olindo S, Signaté A, Grandvaux N, Verlaeten O, Belrose G, de Carvalho Bittencourt M, Hiscott J, Asquith B, Burny A, Smadja D, Césaire R, Willems L.

Blood. 2007 Nov 15;110(10):3722-8. Epub 2007 Aug 23.

44.

Complete suppression of viral gene expression is associated with the onset and progression of lymphoid malignancy: observations in Bovine Leukemia Virus-infected sheep.

Merimi M, Klener P, Szynal M, Cleuter Y, Bagnis C, Kerkhofs P, Burny A, Martiat P, Van den Broeke A.

Retrovirology. 2007 Jul 23;4:51.

45.

Transcriptional regulation of the bovine leukemia virus promoter by the cyclic AMP-response element modulator tau isoform.

Nguyên TL, de Walque S, Veithen E, Dekoninck A, Martinelli V, de Launoit Y, Burny A, Harrod R, Van Lint C.

J Biol Chem. 2007 Jul 20;282(29):20854-67. Epub 2007 May 25.

46.

Suppression of viral gene expression in bovine leukemia virus-associated B-cell malignancy: interplay of epigenetic modifications leading to chromatin with a repressive histone code.

Merimi M, Klener P, Szynal M, Cleuter Y, Kerkhofs P, Burny A, Martiat P, Van den Broeke A.

J Virol. 2007 Jun;81(11):5929-39. Epub 2007 Mar 28.

47.

Mechanisms of leukemogenesis induced by bovine leukemia virus: prospects for novel anti-retroviral therapies in human.

Gillet N, Florins A, Boxus M, Burteau C, Nigro A, Vandermeers F, Balon H, Bouzar AB, Defoiche J, Burny A, Reichert M, Kettmann R, Willems L.

Retrovirology. 2007 Mar 16;4:18. Review.

48.

HTLV-I infection of WE17/10 CD4+ cell line leads to progressive alteration of Ca2+ influx that eventually results in loss of CD7 expression and activation of an antiapoptotic pathway involving AKT and BAD which paves the way for malignant transformation.

Akl H, Badran BM, Zein NE, Bex F, Sotiriou C, Willard-Gallo KE, Burny A, Martiat P.

Leukemia. 2007 Apr;21(4):788-96. Epub 2007 Feb 8. Erratum in: Leukemia. 2009 Nov;23(11):2187. Zein, N E [corrected to Zein, N El].

PMID:
17287851
49.

DNA vaccine encoding endosome-targeted human papillomavirus type 16 E7 protein generates CD4+ T cell-dependent protection.

Brulet JM, Maudoux F, Thomas S, Thielemans K, Burny A, Leo O, Bex F, Hallez S.

Eur J Immunol. 2007 Feb;37(2):376-84.

50.

Bortezomib (PS-341, Velcade) increases the efficacy of trastuzumab (Herceptin) in HER-2-positive breast cancer cells in a synergistic manner.

Cardoso F, Durbecq V, Laes JF, Badran B, Lagneaux L, Bex F, Desmedt C, Willard-Gallo K, Ross JS, Burny A, Piccart M, Sotiriou C.

Mol Cancer Ther. 2006 Dec;5(12):3042-51. Epub 2006 Dec 5.

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