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Items: 12


Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies.

Brydges SD, Broderick L, McGeough MD, Pena CA, Mueller JL, Hoffman HM.

J Clin Invest. 2013 Nov;123(11):4695-705.


Cutting edge: IL-6 is a marker of inflammation with no direct role in inflammasome-mediated mouse models.

McGeough MD, Pena CA, Mueller JL, Pociask DA, Broderick L, Hoffman HM, Brydges SD.

J Immunol. 2012 Sep 15;189(6):2707-11. doi: 10.4049/jimmunol.1101737. Epub 2012 Aug 17.


Constitutively activated NLRP3 inflammasome causes inflammation and abnormal skeletal development in mice.

Bonar SL, Brydges SD, Mueller JL, McGeough MD, Pena C, Chen D, Grimston SK, Hickman-Brecks CL, Ravindran S, McAlinden A, Novack DV, Kastner DL, Civitelli R, Hoffman HM, Mbalaviele G.

PLoS One. 2012;7(4):e35979. doi: 10.1371/journal.pone.0035979. Epub 2012 Apr 27.


Autoinflammation: translating mechanism to therapy.

Doherty TA, Brydges SD, Hoffman HM.

J Leukoc Biol. 2011 Jul;90(1):37-47. doi: 10.1189/jlb.1110616. Epub 2011 Feb 17. Review.


Genetic and molecular basis of inflammasome-mediated disease.

Hoffman HM, Brydges SD.

J Biol Chem. 2011 Apr 1;286(13):10889-96. doi: 10.1074/jbc.R110.135491. Epub 2011 Feb 4. Review. No abstract available.


Pyrin Modulates the Intracellular Distribution of PSTPIP1.

Waite AL, Schaner P, Richards N, Balci-Peynircioglu B, Masters SL, Brydges SD, Fox M, Hong A, Yilmaz E, Kastner DL, Reinherz EL, Gumucio DL.

PLoS One. 2009 Jul 7;4(7):e6147. doi: 10.1371/journal.pone.0006147.


Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity.

Brydges SD, Mueller JL, McGeough MD, Pena CA, Misaghi A, Gandhi C, Putnam CD, Boyle DL, Firestein GS, Horner AA, Soroosh P, Watford WT, O'Shea JJ, Kastner DL, Hoffman HM.

Immunity. 2009 Jun 19;30(6):875-87. doi: 10.1016/j.immuni.2009.05.005. Epub 2009 Jun 4.


A transient forward-targeting element for microneme-regulated secretion in Toxoplasma gondii.

Brydges SD, Harper JM, Parussini F, Coppens I, Carruthers VB.

Biol Cell. 2008 Apr;100(4):253-64.


Targeted deletion of MIC5 enhances trimming proteolysis of Toxoplasma invasion proteins.

Brydges SD, Zhou XW, Huynh MH, Harper JM, Mital J, Adjogble KD, Däubener W, Ward GE, Carruthers VB.

Eukaryot Cell. 2006 Dec;5(12):2174-83. Epub 2006 Sep 15.


Neospora caninum expresses an unusual single-domain Kazal protease inhibitor that is discharged into the parasitophorous vacuole.

Morris MT, Cheng WC, Zhou XW, Brydges SD, Carruthers VB.

Int J Parasitol. 2004 May;34(6):693-701.


Molecular characterization of TgMIC5, a proteolytically processed antigen secreted from the micronemes of Toxoplasma gondii.

Brydges SD, Sherman GD, Nockemann S, Loyens A, Däubener W, Dubremetz JF, Carruthers VB.

Mol Biochem Parasitol. 2000 Nov;111(1):51-66.


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