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Items: 1 to 50 of 96

1.

Talin - the master of integrin adhesions.

Klapholz B, Brown NH.

J Cell Sci. 2017 Aug 1;130(15):2435-2446. doi: 10.1242/jcs.190991. Epub 2017 Jul 12. Review.

2.

Diverse integrin adhesion stoichiometries caused by varied actomyosin activity.

Bulgakova NA, Wellmann J, Brown NH.

Open Biol. 2017 Apr;7(4). pii: 160250. doi: 10.1098/rsob.160250.

3.

Drosophila vinculin is more harmful when hyperactive than absent, and can circumvent integrin to form adhesion complexes.

Maartens AP, Wellmann J, Wictome E, Klapholz B, Green H, Brown NH.

J Cell Sci. 2016 Dec 1;129(23):4354-4365. Epub 2016 Oct 13.

4.

Microtubule organization is determined by the shape of epithelial cells.

Gomez JM, Chumakova L, Bulgakova NA, Brown NH.

Nat Commun. 2016 Oct 25;7:13172. doi: 10.1038/ncomms13172.

5.

Evidence for the mechanosensor function of filamin in tissue development.

Huelsmann S, Rintanen N, Sethi R, Brown NH, Ylänne J.

Sci Rep. 2016 Sep 6;6:32798. doi: 10.1038/srep32798.

6.

An upright eyedrop bottle: accuracy, usage of excess drops, and contamination compared to a conventional bottle.

Davies IJ, Brown NH, Wen JC, Stinnett SS, Kubelick K, Patel RP, Benokraitis KL, Greene L, Cheek C, Muir KW.

Clin Ophthalmol. 2016 Jul 28;10:1411-7. doi: 10.2147/OPTH.S104751. eCollection 2016.

7.

Drosophila p120-catenin is crucial for endocytosis of the dynamic E-cadherin-Bazooka complex.

Bulgakova NA, Brown NH.

J Cell Sci. 2016 Feb 1;129(3):477-82. doi: 10.1242/jcs.177527. Epub 2015 Dec 23.

8.

Visual Acuity in Orbital Floor Fractures: Does Surgical Subspecialty Management Matter?

Richards NQ, Brown NH, Kidwell ED Jr.

J Craniofac Surg. 2015 Jul;26(5):1668-72. doi: 10.1097/SCS.0000000000001743.

PMID:
26163843
9.

Alternative mechanisms for talin to mediate integrin function.

Klapholz B, Herbert SL, Wellmann J, Johnson R, Parsons M, Brown NH.

Curr Biol. 2015 Mar 30;25(7):847-57. doi: 10.1016/j.cub.2015.01.043. Epub 2015 Mar 5.

10.

Anchors and signals: the diverse roles of integrins in development.

Maartens AP, Brown NH.

Curr Top Dev Biol. 2015;112:233-72. doi: 10.1016/bs.ctdb.2014.11.020. Epub 2015 Feb 11. Review.

PMID:
25733142
11.

The many faces of cell adhesion during Drosophila muscle development.

Maartens AP, Brown NH.

Dev Biol. 2015 May 1;401(1):62-74. doi: 10.1016/j.ydbio.2014.12.038. Epub 2015 Jan 14. Review.

12.

Nuclear positioning by actin cables and perinuclear actin: Special and general?

Huelsmann S, Brown NH.

Nucleus. 2014 May-Jun;5(3):219-23. doi: 10.4161/nucl.29405. Epub 2014 Jun 6. Review.

13.

Spectraplakins.

Huelsmann S, Brown NH.

Curr Biol. 2014 Apr 14;24(8):R307-8. doi: 10.1016/j.cub.2014.02.003. No abstract available.

14.

The Drosophila phenotype ontology.

Osumi-Sutherland D, Marygold SJ, Millburn GH, McQuilton PA, Ponting L, Stefancsik R, Falls K, Brown NH, Gkoutos GV.

J Biomed Semantics. 2013 Oct 18;4(1):30. doi: 10.1186/2041-1480-4-30.

15.

Filopodia-like actin cables position nuclei in association with perinuclear actin in Drosophila nurse cells.

Huelsmann S, Ylänne J, Brown NH.

Dev Cell. 2013 Sep 30;26(6):604-15. doi: 10.1016/j.devcel.2013.08.014.

16.

Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms.

Shulman JM, Imboywa S, Giagtzoglou N, Powers MP, Hu Y, Devenport D, Chipendo P, Chibnik LB, Diamond A, Perrimon N, Brown NH, De Jager PL, Feany MB.

Hum Mol Genet. 2014 Feb 15;23(4):870-7. doi: 10.1093/hmg/ddt478. Epub 2013 Sep 25.

17.

Dynamic microtubules produce an asymmetric E-cadherin-Bazooka complex to maintain segment boundaries.

Bulgakova NA, Grigoriev I, Yap AS, Akhmanova A, Brown NH.

J Cell Biol. 2013 Jun 10;201(6):887-901. doi: 10.1083/jcb.201211159.

18.

Gene Ontology annotations and resources.

Gene Ontology Consortium, Blake JA, Dolan M, Drabkin H, Hill DP, Li N, Sitnikov D, Bridges S, Burgess S, Buza T, McCarthy F, Peddinti D, Pillai L, Carbon S, Dietze H, Ireland A, Lewis SE, Mungall CJ, Gaudet P, Chrisholm RL, Fey P, Kibbe WA, Basu S, Siegele DA, McIntosh BK, Renfro DP, Zweifel AE, Hu JC, Brown NH, Tweedie S, Alam-Faruque Y, Apweiler R, Auchinchloss A, Axelsen K, Bely B, Blatter M-, Bonilla C, Bouguerleret L, Boutet E, Breuza L, Bridge A, Chan WM, Chavali G, Coudert E, Dimmer E, Estreicher A, Famiglietti L, Feuermann M, Gos A, Gruaz-Gumowski N, Hieta R, Hinz C, Hulo C, Huntley R, James J, Jungo F, Keller G, Laiho K, Legge D, Lemercier P, Lieberherr D, Magrane M, Martin MJ, Masson P, Mutowo-Muellenet P, O'Donovan C, Pedruzzi I, Pichler K, Poggioli D, Porras Millán P, Poux S, Rivoire C, Roechert B, Sawford T, Schneider M, Stutz A, Sundaram S, Tognolli M, Xenarios I, Foulgar R, Lomax J, Roncaglia P, Khodiyar VK, Lovering RC, Talmud PJ, Chibucos M, Giglio MG, Chang H-, Hunter S, McAnulla C, Mitchell A, Sangrador A, Stephan R, Harris MA, Oliver SG, Rutherford K, Wood V, Bahler J, Lock A, Kersey PJ, McDowall DM, Staines DM, Dwinell M, Shimoyama M, Laulederkind S, Hayman T, Wang S-, Petri V, Lowry T, D'Eustachio P, Matthews L, Balakrishnan R, Binkley G, Cherry JM, Costanzo MC, Dwight SS, Engel SR, Fisk DG, Hitz BC, Hong EL, Karra K, Miyasato SR, Nash RS, Park J, Skrzypek MS, Weng S, Wong ED, Berardini TZ, Huala E, Mi H, Thomas PD, Chan J, Kishore R, Sternberg P, Van Auken K, Howe D, Westerfield M.

Nucleic Acids Res. 2013 Jan;41(Database issue):D530-5. doi: 10.1093/nar/gks1050. Epub 2012 Nov 17.

19.

Cell adhesion in Drosophila: versatility of cadherin and integrin complexes during development.

Bulgakova NA, Klapholz B, Brown NH.

Curr Opin Cell Biol. 2012 Oct;24(5):702-12. doi: 10.1016/j.ceb.2012.07.006. Epub 2012 Aug 28. Review.

20.

Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens.

Ratheesh A, Gomez GA, Priya R, Verma S, Kovacs EM, Jiang K, Brown NH, Akhmanova A, Stehbens SJ, Yap AS.

Nat Cell Biol. 2012 Aug;14(8):818-828. doi: 10.1038/ncb2532. Epub 2012 Jul 1.

21.

Directly e-mailing authors of newly published papers encourages community curation.

Bunt SM, Grumbling GB, Field HI, Marygold SJ, Brown NH, Millburn GH; FlyBase Consortium.

Database (Oxford). 2012 May 2;2012:bas024. doi: 10.1093/database/bas024. Print 2012.

22.

Extracellular matrix in development: insights from mechanisms conserved between invertebrates and vertebrates.

Brown NH.

Cold Spring Harb Perspect Biol. 2011 Dec 1;3(12). pii: a005082. doi: 10.1101/cshperspect.a005082. Review.

23.

A central multifunctional role of integrin-linked kinase at muscle attachment sites.

Zervas CG, Psarra E, Williams V, Solomon E, Vakaloglou KM, Brown NH.

J Cell Sci. 2011 Apr 15;124(Pt 8):1316-27. doi: 10.1242/jcs.081422.

24.

Drosophila Ajuba is not an Aurora-A activator but is required to maintain Aurora-A at the centrosome.

Sabino D, Brown NH, Basto R.

J Cell Sci. 2011 Apr 1;124(Pt 7):1156-66. doi: 10.1242/jcs.076711.

25.

Downstream of identity genes: muscle-type-specific regulation of the fusion process.

Bataillé L, Delon I, Da Ponte JP, Brown NH, Jagla K.

Dev Cell. 2010 Aug 17;19(2):317-28. doi: 10.1016/j.devcel.2010.07.008.

26.

Spatial heterogeneity of restitution properties and the onset of alternans.

Dobrovolny HM, Berger CM, Brown NH, Neu WK, Gauthier DJ.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:4186-9. doi: 10.1109/IEMBS.2009.5333929.

PMID:
19964626
27.

Drosophila laminins act as key regulators of basement membrane assembly and morphogenesis.

Urbano JM, Torgler CN, Molnar C, Tepass U, López-Varea A, Brown NH, de Celis JF, Martín-Bermudo MD.

Development. 2009 Dec;136(24):4165-76. doi: 10.1242/dev.044263. Epub 2009 Nov 11.

28.

The integrin adhesion complex changes its composition and function during morphogenesis of an epithelium.

Delon I, Brown NH.

J Cell Sci. 2009 Dec 1;122(Pt 23):4363-74. doi: 10.1242/jcs.055996. Epub 2009 Nov 10.

29.

Using a structured image database, how well can novices assign skin lesion images to the correct diagnostic grouping?

Brown NH, Robertson KM, Bisset YC, Rees JL.

J Invest Dermatol. 2009 Oct;129(10):2509-12. doi: 10.1038/jid.2009.75. Epub 2009 Apr 2. No abstract available.

30.

Developing SDOCT to assess donor human eyes prior to tissue sectioning for research.

Brown NH, Koreishi AF, McCall M, Izatt JA, Rickman CB, Toth CA.

Graefes Arch Clin Exp Ophthalmol. 2009 Aug;247(8):1069-80. doi: 10.1007/s00417-009-1044-3. Epub 2009 Feb 19.

31.

Spectraplakins: the cytoskeleton's Swiss army knife.

Brown NH.

Cell. 2008 Oct 3;135(1):16-8. doi: 10.1016/j.cell.2008.09.023.

32.

Grainy head promotes expression of septate junction proteins and influences epithelial morphogenesis.

Narasimha M, Uv A, Krejci A, Brown NH, Bray SJ.

J Cell Sci. 2008 Mar 15;121(Pt 6):747-52. doi: 10.1242/jcs.019422. Epub 2008 Feb 26.

33.

Integrin-dependent anchoring of a stem-cell niche.

Tanentzapf G, Devenport D, Godt D, Brown NH.

Nat Cell Biol. 2007 Dec;9(12):1413-8. Epub 2007 Nov 4.

34.

Mutations in the Drosophila alphaPS2 integrin subunit uncover new features of adhesion site assembly.

Devenport D, Bunch TA, Bloor JW, Brower DL, Brown NH.

Dev Biol. 2007 Aug 15;308(2):294-308. Epub 2007 Apr 12.

35.

The MARVEL domain protein, Singles Bar, is required for progression past the pre-fusion complex stage of myoblast fusion.

Estrada B, Maeland AD, Gisselbrecht SS, Bloor JW, Brown NH, Michelson AM.

Dev Biol. 2007 Jul 15;307(2):328-39. Epub 2007 May 3.

36.

A fiber-based ratiometric optical cardiac mapping channel using a diffraction grating and split detector.

Brown NH, Dobrovolny HM, Gauthier DJ, Wolf PD.

Biophys J. 2007 Jul 1;93(1):254-63. Epub 2007 Apr 6.

37.

Integrin-ECM interactions regulate the changes in cell shape driving the morphogenesis of the Drosophila wing epithelium.

Domínguez-Giménez P, Brown NH, Martín-Bermudo MD.

J Cell Sci. 2007 Mar 15;120(Pt 6):1061-71. Epub 2007 Feb 27.

38.

Integrins and the actin cytoskeleton.

Delon I, Brown NH.

Curr Opin Cell Biol. 2007 Feb;19(1):43-50. Epub 2006 Dec 20. Review.

PMID:
17184985
39.

The Drosophila RASSF homolog antagonizes the hippo pathway.

Polesello C, Huelsmann S, Brown NH, Tapon N.

Curr Biol. 2006 Dec 19;16(24):2459-65.

40.
41.

Multiple factors contribute to integrin-talin interactions in vivo.

Tanentzapf G, Martin-Bermudo MD, Hicks MS, Brown NH.

J Cell Sci. 2006 Apr 15;119(Pt 8):1632-44. Epub 2006 Mar 28.

42.

Contribution of sequence variation in Drosophila actins to their incorporation into actin-based structures in vivo.

Röper K, Mao Y, Brown NH.

J Cell Sci. 2005 Sep 1;118(Pt 17):3937-48. Epub 2005 Aug 16.

43.

Integrin-independent repression of cadherin transcription by talin during axis formation in Drosophila.

Bécam IE, Tanentzapf G, Lepesant JA, Brown NH, Huynh JR.

Nat Cell Biol. 2005 May;7(5):510-6. Epub 2005 Apr 24.

PMID:
15852002
44.
45.

Focal adhesion kinase is not required for integrin function or viability in Drosophila.

Grabbe C, Zervas CG, Hunter T, Brown NH, Palmer RH.

Development. 2004 Dec;131(23):5795-805. Epub 2004 Nov 3.

46.

Morphogenesis in the absence of integrins: mutation of both Drosophila beta subunits prevents midgut migration.

Devenport D, Brown NH.

Development. 2004 Nov;131(21):5405-15. Epub 2004 Oct 6.

47.

Tensin stabilizes integrin adhesive contacts in Drosophila.

Torgler CN, Narasimha M, Knox AL, Zervas CG, Vernon MC, Brown NH.

Dev Cell. 2004 Mar;6(3):357-69.

48.

Novel functions for integrins in epithelial morphogenesis.

Narasimha M, Brown NH.

Curr Biol. 2004 Mar 9;14(5):381-5.

49.
50.

Reducing integrins improves the quality of fly life.

Torgler CN, Brown NH.

Sci Aging Knowledge Environ. 2003 Oct 8;2003(40):PE28. Review.

PMID:
14534327

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