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Background and method of the Striving to be Strong study a RCT testing the efficacy of a m-health self-management intervention.

Ryan P, Papanek P, Csuka ME, Brown ME, Hopkins S, Lynch S, Scheer V, Schlidt A, Yan K, Simpson P, Hoffman R; Striving to be Strong Team.

Contemp Clin Trials. 2018 Jun 9;71:80-87. doi: 10.1016/j.cct.2018.06.006. [Epub ahead of print]


A Humanized Mouse Model Generated Using Surplus Neonatal Tissue.

Brown ME, Zhou Y, McIntosh BE, Norman IG, Lou HE, Biermann M, Sullivan JA, Kamp TJ, Thomson JA, Anagnostopoulos PV, Burlingham WJ.

Stem Cell Reports. 2018 Apr 10;10(4):1175-1183. doi: 10.1016/j.stemcr.2018.02.011. Epub 2018 Mar 22.


Myosin light chain kinase ( MYLK) coding polymorphisms modulate human lung endothelial cell barrier responses via altered tyrosine phosphorylation, spatial localization, and lamellipodial protrusions.

Wang T, Brown ME, Kelly GT, Camp SM, Mascarenhas JB, Sun X, Dudek SM, Garcia JGN.

Pulm Circ. 2018 Apr-Jun;8(2):2045894018764171. doi: 10.1177/2045894018764171. Epub 2018 Feb 26.


Identification of targeting peptides for the diagnosis of myocarditis.

Martinez MD, Trac DQ, Brown ME, Maher KO, Davis ME.

Nanomedicine (Lond). 2018 Apr 1;13(7):787-801. doi: 10.2217/nnm-2018-0023. Epub 2018 Feb 23.


Evaluation of Hydrogels Presenting Extracellular Matrix-Derived Adhesion Peptides and Encapsulating Cardiac Progenitor Cells for Cardiac Repair.

Bhutani S, Nachlas ALY, Brown ME, Pete T, Johnson CT, García AJ, Davis ME.

ACS Biomater Sci Eng. 2018 Jan 8;4(1):200-210. doi: 10.1021/acsbiomaterials.7b00502. Epub 2017 Nov 17.


Cryopreservation effects on sperm function and fertility in two threatened crane species.

Brown ME, Singh RP, Pukazhenthi B, Keefer CL, Songsasen N.

Cryobiology. 2018 Jun;82:148-154. doi: 10.1016/j.cryobiol.2018.01.010. Epub 2018 Feb 3.


A multi-country assessment of factors related to smallholder food security in varying rainfall conditions.

Niles MT, Brown ME.

Sci Rep. 2017 Nov 24;7(1):16277. doi: 10.1038/s41598-017-16282-9.


Testing of a bioactive, moldable bone graft substitute in an infected, critically sized segmental defect model.

Brown ME, Zou Y, Peyyala R, Huja SS, Cunningham LL, Milbrandt TA, Dziubla TD, Puleo DA.

J Biomed Mater Res B Appl Biomater. 2017 Sep 19. doi: 10.1002/jbm.b.34001. [Epub ahead of print]


Zika virus activates de novo and cross-reactive memory B cell responses in dengue-experienced donors.

Rogers TF, Goodwin EC, Briney B, Sok D, Beutler N, Strubel A, Nedellec R, Le K, Brown ME, Burton DR, Walker LM.

Sci Immunol. 2017 Aug 18;2(14). pii: eaan6809. doi: 10.1126/sciimmunol.aan6809.


Early-stage attenuation of phase-amplitude coupling in the hippocampus and medial prefrontal cortex in a transgenic rat model of Alzheimer's disease.

Bazzigaluppi P, Beckett TL, Koletar MM, Lai AY, Joo IL, Brown ME, Carlen PL, McLaurin J, Stefanovic B.

J Neurochem. 2018 Mar;144(5):669-679. doi: 10.1111/jnc.14136. Epub 2017 Oct 10.


Toe Walking: When Do We Need to Worry?

Morozova OM, Chang TF, Brown ME.

Curr Probl Pediatr Adolesc Health Care. 2017 Jul;47(7):156-160. doi: 10.1016/j.cppeds.2017.06.004. Epub 2017 Jul 15.


Functional characterization of human pluripotent stem cell-derived arterial endothelial cells.

Zhang J, Chu LF, Hou Z, Schwartz MP, Hacker T, Vickerman V, Swanson S, Leng N, Nguyen BK, Elwell A, Bolin J, Brown ME, Stewart R, Burlingham WJ, Murphy WL, Thomson JA.

Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6072-E6078. doi: 10.1073/pnas.1702295114. Epub 2017 Jul 10.


The ARP 2/3 complex mediates endothelial barrier function and recovery.

Belvitch P, Brown ME, Brinley BN, Letsiou E, Rizzo AN, Garcia JGN, Dudek SM.

Pulm Circ. 2017 Feb 1;7(1):200-210. doi: 10.1086/690307. eCollection 2017 Mar.


Early neurovascular dysfunction in a transgenic rat model of Alzheimer's disease.

Joo IL, Lai AY, Bazzigaluppi P, Koletar MM, Dorr A, Brown ME, Thomason LA, Sled JG, McLaurin J, Stefanovic B.

Sci Rep. 2017 Apr 12;7:46427. doi: 10.1038/srep46427.


Labeling of neuronal morphology using custom diolistic techniques.

Hough LH, Brown ME.

J Neurosci Methods. 2017 Apr 15;282:43-51. doi: 10.1016/j.jneumeth.2017.03.004. Epub 2017 Mar 6.


High-throughput screening identifies microRNAs that target Nox2 and improve function after acute myocardial infarction.

Yang J, Brown ME, Zhang H, Martinez M, Zhao Z, Bhutani S, Yin S, Trac D, Xi JJ, Davis ME.

Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H1002-H1012. doi: 10.1152/ajpheart.00685.2016. Epub 2017 Feb 24.


Life history plasticity does not confer resilience to environmental change in the mole salamander (Ambystoma talpoideum).

Davis CL, Miller DA, Walls SC, Barichivich WJ, Riley J, Brown ME.

Oecologia. 2017 Mar;183(3):739-749. doi: 10.1007/s00442-017-3810-y. Epub 2017 Jan 12.


Species interactions and the effects of climate variability on a wetland amphibian metacommunity.

Davis CL, Miller DA, Walls SC, Barichivich WJ, Riley JW, Brown ME.

Ecol Appl. 2017 Jan;27(1):285-296. doi: 10.1002/eap.1442.


Pharmacokinetics and derivation of an anticancer dosing regimen for the novel anti-cancer agent isobutyl-deoxynyboquinone (IB-DNQ), a NQO1 bioactivatable molecule, in the domestic felid species.

Lundberg AP, Francis JM, Pajak M, Parkinson EI, Wycislo KL, Rosol TJ, Brown ME, London CA, Dirikolu L, Hergenrother PJ, Fan TM.

Invest New Drugs. 2017 Apr;35(2):134-144. doi: 10.1007/s10637-016-0414-z. Epub 2016 Dec 14.


Long-term follow-up of Fournier's Gangrene in a tertiary care center.

Rosen DR, Brown ME, Cologne KG, Ault GT, Strumwasser AM.

J Surg Res. 2016 Nov;206(1):175-181. doi: 10.1016/j.jss.2016.06.091. Epub 2016 Jul 15.


Experimental, Systems, and Computational Approaches to Understanding the MicroRNA-Mediated Reparative Potential of Cardiac Progenitor Cell-Derived Exosomes From Pediatric Patients.

Agarwal U, George A, Bhutani S, Ghosh-Choudhary S, Maxwell JT, Brown ME, Mehta Y, Platt MO, Liang Y, Sahoo S, Davis ME.

Circ Res. 2017 Feb 17;120(4):701-712. doi: 10.1161/CIRCRESAHA.116.309935. Epub 2016 Nov 21. Erratum in: Circ Res. 2017 May 12;120(10 ):e45.


Resilience in Men and Women Experiencing Sexual Assault or Traumatic Stress: Validation and Replication of the Scale of Protective Factors.

Ponce-Garcia E, Madewell AN, Brown ME.

J Trauma Stress. 2016 Dec;29(6):537-545. doi: 10.1002/jts.22148. Epub 2016 Nov 17.


Th17 Responses to Collagen Type V, kα1-Tubulin, and Vimentin Are Present Early in Human Development and Persist Throughout Life.

Sullivan JA, Jankowska-Gan E, Hegde S, Pestrak MA, Agashe VV, Park AC, Brown ME, Kernien JF, Wilkes DS, Kaufman DB, Greenspan DS, Burlingham WJ.

Am J Transplant. 2017 Apr;17(4):944-956. doi: 10.1111/ajt.14097. Epub 2016 Dec 19.


Effects of Neurotrophic Support and Amyloid-Targeted Combined Therapy on Adult Hippocampal Neurogenesis in a Transgenic Model of Alzheimer's Disease.

Morrone CD, Thomason LA, Brown ME, Aubert I, McLaurin J.

PLoS One. 2016 Oct 21;11(10):e0165393. doi: 10.1371/journal.pone.0165393. eCollection 2016.


Vesicular eruption in a 2-year-old boy.

Rahnama-Moghadam S, Brown ME, Meffert JJ.

J Fam Pract. 2016 Jul;65(7):E1-3.


Influence of cooling and thawing conditions and cryoprotectant concentration on frozen-thawed survival of white-naped crane (Antigone vipio) spermatozoa.

Panyaboriban S, Pukazhenthi B, Brown ME, Crowe C, Lynch W, Singh RP, Techakumphu M, Songsasen N.

Cryobiology. 2016 Oct;73(2):209-15. doi: 10.1016/j.cryobiol.2016.07.009. Epub 2016 Jul 15.


Amyotrophic Lateral Sclerosis with Frontotemporal Dementia in the Presence of C9orf72 Repeat Expansion-A Case Report.

Bonda C, Kolikonda MK, Brown ME, Lippmann S.

Innov Clin Neurosci. 2016 Feb 1;13(1-2):37-9. eCollection 2016 Jan-Feb.


Engineering Bacteria to Catabolize the Carbonaceous Component of Sarin: Teaching E. coli to Eat Isopropanol.

Brown ME, Mukhopadhyay A, Keasling JD.

ACS Synth Biol. 2016 Dec 16;5(12):1485-1496. Epub 2016 Jul 27.


Heterogeneous estrogen receptor expression in circulating tumor cells suggests diverse mechanisms of fulvestrant resistance.

Paoletti C, Larios JM, Muñiz MC, Aung K, Cannell EM, Darga EP, Kidwell KM, Thomas DG, Tokudome N, Brown ME, Connelly MC, Chianese DA, Schott AF, Henry NL, Rae JM, Hayes DF.

Mol Oncol. 2016 Aug;10(7):1078-85. doi: 10.1016/j.molonc.2016.04.006. Epub 2016 Apr 29.


No irradiation required: The future of humanized immune system modeling in murine hosts.

McIntosh BE, Brown ME.

Chimerism. 2015 Apr 3;6(1-2):40-5. doi: 10.1080/19381956.2016.1162360. Epub 2016 May 12. Review.


Age-Dependent Effect of Pediatric Cardiac Progenitor Cells After Juvenile Heart Failure.

Agarwal U, Smith AW, French KM, Boopathy AV, George A, Trac D, Brown ME, Shen M, Jiang R, Fernandez JD, Kogon BE, Kanter KR, Alsoufi B, Wagner MB, Platt MO, Davis ME.

Stem Cells Transl Med. 2016 Jul;5(7):883-92. doi: 10.5966/sctm.2015-0241. Epub 2016 May 5.


Female gonadal hormones and reproductive behaviors as key determinants of successful reproductive output of breeding whooping cranes (Grus americana).

Brown ME, Converse SJ, Chandler JN, Shafer C, Brown JL, Keefer CL, Songsasen N.

Gen Comp Endocrinol. 2016 May 1;230-231:158-65. doi: 10.1016/j.ygcen.2016.04.009. Epub 2016 Apr 11.


Modulation of human allogeneic and syngeneic pluripotent stem cells and immunological implications for transplantation.

Sackett SD, Brown ME, Tremmel DM, Ellis T, Burlingham WJ, Odorico JS.

Transplant Rev (Orlando). 2016 Apr;30(2):61-70. doi: 10.1016/j.trre.2016.02.001. Epub 2016 Feb 10. Review.


Knockdown of TNF-α by DNAzyme gold nanoparticles as an anti-inflammatory therapy for myocardial infarction.

Somasuntharam I, Yehl K, Carroll SL, Maxwell JT, Martinez MD, Che PL, Brown ME, Salaita K, Davis ME.

Biomaterials. 2016 Mar;83:12-22. doi: 10.1016/j.biomaterials.2015.12.022. Epub 2015 Dec 21.


A Case of Psoriasis Replaced by Allergic Contact Dermatitis in a 12-Year-Old Boy.

Brown ME, Browning JC.

Pediatr Dermatol. 2016 Mar-Apr;33(2):e125-6. doi: 10.1111/pde.12737. Epub 2015 Dec 9.


TRPC6 channel translocation into phagosomal membrane augments phagosomal function.

Riazanski V, Gabdoulkhakova AG, Boynton LS, Eguchi RR, Deriy LV, Hogarth DK, Loaëc N, Oumata N, Galons H, Brown ME, Shevchenko P, Gallan AJ, Yoo SG, Naren AP, Villereal ML, Beacham DW, Bindokas VP, Birnbaumer L, Meijer L, Nelson DJ.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6486-95. doi: 10.1073/pnas.1518966112. Epub 2015 Nov 10.


Bioengineered vocal fold mucosa for voice restoration.

Ling C, Li Q, Brown ME, Kishimoto Y, Toya Y, Devine EE, Choi KO, Nishimoto K, Norman IG, Tsegyal T, Jiang JJ, Burlingham WJ, Gunasekaran S, Smith LM, Frey BL, Welham NV.

Sci Transl Med. 2015 Nov 18;7(314):314ra187. doi: 10.1126/scitranslmed.aab4014.


Bedside Optic Nerve Sheath Diameter Assessment in the Identification of Increased Intracranial Pressure in Suspected Idiopathic Intracranial Hypertension.

Irazuzta JE, Brown ME, Akhtar J.

Pediatr Neurol. 2016 Jan;54:35-8. doi: 10.1016/j.pediatrneurol.2015.08.009. Epub 2015 Aug 28.


Characterization of STAT3 expression, signaling and inhibition in feline oral squamous cell carcinoma.

Brown ME, Bear MD, Rosol TJ, Premanandan C, Kisseberth WC, London CA.

BMC Vet Res. 2015 Aug 14;11:206. doi: 10.1186/s12917-015-0505-7.


Unique Toll-Like Receptor 4 Activation by NAMPT/PBEF Induces NFκB Signaling and Inflammatory Lung Injury.

Camp SM, Ceco E, Evenoski CL, Danilov SM, Zhou T, Chiang ET, Moreno-Vinasco L, Mapes B, Zhao J, Gursoy G, Brown ME, Adyshev DM, Siddiqui SS, Quijada H, Sammani S, Letsiou E, Saadat L, Yousef M, Wang T, Liang J, Garcia JG.

Sci Rep. 2015 Aug 14;5:13135. doi: 10.1038/srep13135.


Time within reproductive season, but not age or inbreeding coefficient, affects seminal and sperm quality in the whooping crane (Grus americana).

Brown ME, Converse SJ, Chandler JN, Crosier AL, Lynch W, Wildt DE, Keefer CL, Songsasen N.

Reprod Fertil Dev. 2017 Feb;29(2):294-306. doi: 10.1071/RD15251.


Structure-Function Analysis of the Non-Muscle Myosin Light Chain Kinase (nmMLCK) Isoform by NMR Spectroscopy and Molecular Modeling: Influence of MYLK Variants.

Shen K, Ramirez B, Mapes B, Shen GR, Gokhale V, Brown ME, Santarsiero B, Ishii Y, Dudek SM, Wang T, Garcia JG.

PLoS One. 2015 Jun 25;10(6):e0130515. doi: 10.1371/journal.pone.0130515. eCollection 2015.


Nano-Biomechanical Study of Spatio-Temporal Cytoskeleton Rearrangements that Determine Subcellular Mechanical Properties and Endothelial Permeability.

Wang X, Bleher R, Brown ME, Garcia JG, Dudek SM, Shekhawat GS, Dravid VP.

Sci Rep. 2015 Jun 18;5:11097. doi: 10.1038/srep11097.


Intramyocardial Delivery of Notch Ligand-Containing Hydrogels Improves Cardiac Function and Angiogenesis Following Infarction.

Boopathy AV, Martinez MD, Smith AW, Brown ME, García AJ, Davis ME.

Tissue Eng Part A. 2015 Sep;21(17-18):2315-22. doi: 10.1089/ten.TEA.2014.0622. Epub 2015 Jul 13.


Depression in type 2 diabetes mellitus: prevalence, impact, and treatment.

Semenkovich K, Brown ME, Svrakic DM, Lustman PJ.

Drugs. 2015 Apr;75(6):577-87. doi: 10.1007/s40265-015-0347-4. Review.


Significance of Circulating Tumor Cells in Metastatic Triple-Negative Breast Cancer Patients within a Randomized, Phase II Trial: TBCRC 019.

Paoletti C, Li Y, Muñiz MC, Kidwell KM, Aung K, Thomas DG, Brown ME, Abramson VG, Irvin WJ Jr, Lin NU, Liu MC, Nanda R, Nangia JR, Storniolo AM, Traina TA, Vaklavas C, Van Poznak CH, Wolff AC, Forero-Torres A, Hayes DF; Translational Breast Cancer Research Consortium (TBCRC).

Clin Cancer Res. 2015 Jun 15;21(12):2771-9. doi: 10.1158/1078-0432.CCR-14-2781. Epub 2015 Mar 16.


Genetic and biochemical investigations of the role of MamP in redox control of iron biomineralization in Magnetospirillum magneticum.

Jones SR, Wilson TD, Brown ME, Rahn-Lee L, Yu Y, Fredriksen LL, Ozyamak E, Komeili A, Chang MC.

Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):3904-9. doi: 10.1073/pnas.1417614112. Epub 2015 Mar 16.


Nonirradiated NOD,B6.SCID Il2rγ-/- Kit(W41/W41) (NBSGW) mice support multilineage engraftment of human hematopoietic cells.

McIntosh BE, Brown ME, Duffin BM, Maufort JP, Vereide DT, Slukvin II, Thomson JA.

Stem Cell Reports. 2015 Feb 10;4(2):171-80. doi: 10.1016/j.stemcr.2014.12.005. Epub 2015 Jan 15.


Remediating agitation-induced antibody aggregation by eradicating exposed hydrophobic motifs.

Clark RH, Latypov RF, De Imus C, Carter J, Wilson Z, Manchulenko K, Brown ME, Ketchem RR.

MAbs. 2014;6(6):1540-50. doi: 10.4161/mabs.36252.


Development of circulating tumor cell-endocrine therapy index in patients with hormone receptor-positive breast cancer.

Paoletti C, Muñiz MC, Thomas DG, Griffith KA, Kidwell KM, Tokudome N, Brown ME, Aung K, Miller MC, Blossom DL, Schott AF, Henry NL, Rae JM, Connelly MC, Chianese DA, Hayes DF.

Clin Cancer Res. 2015 Jun 1;21(11):2487-98. doi: 10.1158/1078-0432.CCR-14-1913. Epub 2014 Nov 7.

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