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Items: 18


Characterization of the Affective Component of Acute Postoperative Pain Associated with a Novel Rat Model of Inguinal Hernia Repair Pain.

Bree D, Moriarty O, Broom DC, Kelly JP, Roche M, Finn DP.

CNS Neurosci Ther. 2016 Feb;22(2):146-53. doi: 10.1111/cns.12483. Epub 2015 Dec 10.


Development and characterization of a novel, anatomically relevant rat model of acute postoperative pain.

Bree D, Moriarty O, O'Mahony CM, Morris B, Bannerton K, Broom DC, Kelly JP, Roche M, Finn DP.

J Pain. 2015 May;16(5):421-35.e1-6. doi: 10.1016/j.jpain.2015.01.010. Epub 2015 Jan 30.


Locomotor activity in a novel environment as a test of inflammatory pain in rats.

Matson DJ, Broom DC, Cortright DN.

Methods Mol Biol. 2010;617:67-78. doi: 10.1007/978-1-60327-323-7_6.


Periganglionic inflammation elicits a distally radiating pain hypersensitivity by promoting COX-2 induction in the dorsal root ganglion.

Amaya F, Samad TA, Barrett L, Broom DC, Woolf CJ.

Pain. 2009 Mar;142(1-2):59-67. doi: 10.1016/j.pain.2008.11.013. Epub 2009 Jan 9.


Characterization of N-(adamantan-1-ylmethyl)-5-[(3R-amino-pyrrolidin-1-yl)methyl]-2-chloro-benzamide, a P2X7 antagonist in animal models of pain and inflammation.

Broom DC, Matson DJ, Bradshaw E, Buck ME, Meade R, Coombs S, Matchett M, Ford KK, Yu W, Yuan J, Sun SH, Ochoa R, Krause JE, Wustrow DJ, Cortright DN.

J Pharmacol Exp Ther. 2008 Dec;327(3):620-33. doi: 10.1124/jpet.108.141853. Epub 2008 Sep 4.


New frontiers in assessing pain and analgesia in laboratory animals.

Cortright DN, Matson DJ, Broom DC.

Expert Opin Drug Discov. 2008 Sep;3(9):1099-108. doi: 10.1517/17460441.3.9.1099.


TRP channels and pain.

Cortright DN, Krause JE, Broom DC.

Biochim Biophys Acta. 2007 Aug;1772(8):978-88. Epub 2007 Mar 19. Review.


Inflammation-induced reduction of spontaneous activity by adjuvant: A novel model to study the effect of analgesics in rats.

Matson DJ, Broom DC, Carson SR, Baldassari J, Kehne J, Cortright DN.

J Pharmacol Exp Ther. 2007 Jan;320(1):194-201. Epub 2006 Oct 18.


Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain.

Chen CL, Broom DC, Liu Y, de Nooij JC, Li Z, Cen C, Samad OA, Jessell TM, Woolf CJ, Ma Q.

Neuron. 2006 Feb 2;49(3):365-77.


Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy.

McCampbell A, Truong D, Broom DC, Allchorne A, Gable K, Cutler RG, Mattson MP, Woolf CJ, Frosch MP, Harmon JM, Dunn TM, Brown RH Jr.

Hum Mol Genet. 2005 Nov 15;14(22):3507-21. Epub 2005 Oct 6.


Blocking caspase activity prevents transsynaptic neuronal apoptosis and the loss of inhibition in lamina II of the dorsal horn after peripheral nerve injury.

Scholz J, Broom DC, Youn DH, Mills CD, Kohno T, Suter MR, Moore KA, Decosterd I, Coggeshall RE, Woolf CJ.

J Neurosci. 2005 Aug 10;25(32):7317-23.


Cyclooxygenase 2 expression in the spared nerve injury model of neuropathic pain.

Broom DC, Samad TA, Kohno T, Tegeder I, Geisslinger G, Woolf CJ.

Neuroscience. 2004;124(4):891-900.


Behavioral effects of delta-opioid receptor agonists: potential antidepressants?

Broom DC, Jutkiewicz EM, Rice KC, Traynor JR, Woods JH.

Jpn J Pharmacol. 2002 Sep;90(1):1-6. Review.


Comparison of receptor mechanisms and efficacy requirements for delta-agonist-induced convulsive activity and antinociception in mice.

Broom DC, Nitsche JF, Pintar JE, Rice KC, Woods JH, Traynor JR.

J Pharmacol Exp Ther. 2002 Nov;303(2):723-9.


Convulsant activity of a non-peptidic delta-opioid receptor agonist is not required for its antidepressant-like effects in Sprague-Dawley rats.

Broom DC, Jutkiewicz EM, Folk JE, Traynor JR, Rice KC, Woods JH.

Psychopharmacology (Berl). 2002 Oct;164(1):42-8. Epub 2002 Jul 30.


Nonpeptidic delta-opioid receptor agonists reduce immobility in the forced swim assay in rats.

Broom DC, Jutkiewicz EM, Folk JE, Traynor JR, Rice KC, Woods JH.

Neuropsychopharmacology. 2002 Jun;26(6):744-55.


BU48: a novel buprenorphine analog that exhibits delta-opioid-mediated convulsions but not delta-opioid-mediated antinociception in mice.

Broom DC, Guo L, Coop A, Husbands SM, Lewis JW, Woods JH, Traynor JR.

J Pharmacol Exp Ther. 2000 Sep;294(3):1195-200.

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