Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 137

1.

A Possible Role for Platelet-Activating Factor Receptor in Amyotrophic Lateral Sclerosis Treatment.

Briones MRS, Snyder AM, Ferreira RC, Neely EB, Connor JR, Broach JR.

Front Neurol. 2018 Feb 6;9:39. doi: 10.3389/fneur.2018.00039. eCollection 2018.

2.

Phosphorylation and nuclear transit modulate the balance between normal function and terminal aggregation of the yeast RNA-binding protein Ssd1.

Kurischko C, Broach JR.

Mol Biol Cell. 2017 Nov 1;28(22):3057-3069. doi: 10.1091/mbc.E17-02-0100. Epub 2017 Sep 6.

3.

Expansion of C9ORF72 in amyotrophic lateral sclerosis correlates with brain-computer interface performance.

Geronimo A, Sheldon KE, Broach JR, Simmons Z, Schiff SJ.

Sci Rep. 2017 Aug 21;7(1):8875. doi: 10.1038/s41598-017-08857-3.

4.

Identification of a rare LAMB4 variant associated with familial diverticulitis through exome sequencing.

Coble JL, Sheldon KE, Yue F, Salameh TJ, Harris LR III, Deiling S, Ruggiero FM, Eshelman MA, Yochum GS, Koltun WA, Gerhard GS, Broach JR.

Hum Mol Genet. 2017 Aug 15;26(16):3212-3220. doi: 10.1093/hmg/ddx204.

PMID:
28595269
5.

Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly.

Chereji RV, Bharatula V, Elfving N, Blomberg J, Larsson M, Morozov AV, Broach JR, Björklund S.

Nucleic Acids Res. 2017 Sep 6;45(15):8806-8821. doi: 10.1093/nar/gkx491.

6.

Separating Putative Pathogens from Background Contamination with Principal Orthogonal Decomposition: Evidence for Leptospira in the Ugandan Neonatal Septisome.

Schiff SJ, Kiwanuka J, Riggio G, Nguyen L, Mu K, Sproul E, Bazira J, Mwanga-Amumpaire J, Tumusiime D, Nyesigire E, Lwanga N, Bogale KT, Kapur V, Broach JR, Morton SU, Warf BC, Poss M.

Front Med (Lausanne). 2016 Jun 13;3:22. doi: 10.3389/fmed.2016.00022. eCollection 2016.

7.

The yeast genome undergoes significant topological reorganization in quiescence.

Rutledge MT, Russo M, Belton JM, Dekker J, Broach JR.

Nucleic Acids Res. 2015 Sep 30;43(17):8299-313. doi: 10.1093/nar/gkv723. Epub 2015 Jul 21.

8.

A dynamic interplay of nucleosome and Msn2 binding regulates kinetics of gene activation and repression following stress.

Elfving N, Chereji RV, Bharatula V, Björklund S, Morozov AV, Broach JR.

Nucleic Acids Res. 2014 May;42(9):5468-82. doi: 10.1093/nar/gku176. Epub 2014 Mar 5.

9.

Genetic heterogeneity of amyotrophic lateral sclerosis: implications for clinical practice and research.

Su XW, Broach JR, Connor JR, Gerhard GS, Simmons Z.

Muscle Nerve. 2014 Jun;49(6):786-803. doi: 10.1002/mus.24198. Epub 2014 Apr 8. Review.

PMID:
24488689
10.

The yeast environmental stress response regulates mutagenesis induced by proteotoxic stress.

Shor E, Fox CA, Broach JR.

PLoS Genet. 2013;9(8):e1003680. doi: 10.1371/journal.pgen.1003680. Epub 2013 Aug 1.

11.

Nucleotide degradation and ribose salvage in yeast.

Xu YF, Létisse F, Absalan F, Lu W, Kuznetsova E, Brown G, Caudy AA, Yakunin AF, Broach JR, Rabinowitz JD.

Mol Syst Biol. 2013 May 14;9:665. doi: 10.1038/msb.2013.21.

12.

Noise and interlocking signaling pathways promote distinct transcription factor dynamics in response to different stresses.

Petrenko N, Chereji RV, McClean MN, Morozov AV, Broach JR.

Mol Biol Cell. 2013 Jun;24(12):2045-57. doi: 10.1091/mbc.E12-12-0870. Epub 2013 Apr 24.

13.

High hydrostatic pressure activates transcription factors involved in Saccharomyces cerevisiae stress tolerance.

Bravim F, da Silva LF, Souza DT, Lippman SI, Broach JR, Fernandes AA, Fernandes PM.

Curr Pharm Biotechnol. 2012 Dec;13(15):2712-20.

14.

Nutritional control of growth and development in yeast.

Broach JR.

Genetics. 2012 Sep;192(1):73-105. doi: 10.1534/genetics.111.135731. Review.

15.

High hydrostatic pressure activates gene expression that leads to ethanol production enhancement in a Saccharomyces cerevisiae distillery strain.

Bravim F, Lippman SI, da Silva LF, Souza DT, Fernandes AA, Masuda CA, Broach JR, Fernandes PM.

Appl Microbiol Biotechnol. 2013 Mar;97(5):2093-107. doi: 10.1007/s00253-012-4356-x. Epub 2012 Aug 23.

16.

Regulation of yeast pyruvate kinase by ultrasensitive allostery independent of phosphorylation.

Xu YF, Zhao X, Glass DS, Absalan F, Perlman DH, Broach JR, Rabinowitz JD.

Mol Cell. 2012 Oct 12;48(1):52-62. doi: 10.1016/j.molcel.2012.07.013. Epub 2012 Aug 16.

17.

Decoding complex chemical mixtures with a physical model of a sensor array.

Tsitron J, Ault AD, Broach JR, Morozov AV.

PLoS Comput Biol. 2011 Oct;7(10):e1002224. doi: 10.1371/journal.pcbi.1002224. Epub 2011 Oct 20.

18.

Chromatin remodelers clear nucleosomes from intrinsically unfavorable sites to establish nucleosome-depleted regions at promoters.

Tolkunov D, Zawadzki KA, Singer C, Elfving N, Morozov AV, Broach JR.

Mol Biol Cell. 2011 Jun 15;22(12):2106-18. doi: 10.1091/mbc.E10-10-0826. Epub 2011 Apr 20.

19.

Yeast cells can access distinct quiescent states.

Klosinska MM, Crutchfield CA, Bradley PH, Rabinowitz JD, Broach JR.

Genes Dev. 2011 Feb 15;25(4):336-49. doi: 10.1101/gad.2011311. Epub 2011 Feb 2.

20.

Initiation of the TORC1-regulated G0 program requires Igo1/2, which license specific mRNAs to evade degradation via the 5'-3' mRNA decay pathway.

Talarek N, Cameroni E, Jaquenoud M, Luo X, Bontron S, Lippman S, Devgan G, Snyder M, Broach JR, De Virgilio C.

Mol Cell. 2010 May 14;38(3):345-55. doi: 10.1016/j.molcel.2010.02.039.

21.

The origin recognition complex interacts with a subset of metabolic genes tightly linked to origins of replication.

Shor E, Warren CL, Tietjen J, Hou Z, Müller U, Alborelli I, Gohard FH, Yemm AI, Borisov L, Broach JR, Weinreich M, Nieduszynski CA, Ansari AZ, Fox CA.

PLoS Genet. 2009 Dec;5(12):e1000755. doi: 10.1371/journal.pgen.1000755. Epub 2009 Dec 4.

22.

Protein kinase A and TORC1 activate genes for ribosomal biogenesis by inactivating repressors encoded by Dot6 and its homolog Tod6.

Lippman SI, Broach JR.

Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19928-33. doi: 10.1073/pnas.0907027106. Epub 2009 Nov 9.

23.
24.

Expression of CXCR4, a G-protein-coupled receptor for CXCL12 in yeast identification of new-generation inverse agonists.

Evans BJ, Wang Z, Broach JR, Oishi S, Fujii N, Peiper SC.

Methods Enzymol. 2009;460:399-412. doi: 10.1016/S0076-6879(09)05220-3.

PMID:
19446737
25.

Microarray profiling of phage-display selections for rapid mapping of transcription factor-DNA interactions.

Freckleton G, Lippman SI, Broach JR, Tavazoie S.

PLoS Genet. 2009 Apr;5(4):e1000449. doi: 10.1371/journal.pgen.1000449. Epub 2009 Apr 10.

26.

Glucose regulates transcription in yeast through a network of signaling pathways.

Zaman S, Lippman SI, Schneper L, Slonim N, Broach JR.

Mol Syst Biol. 2009;5:245. doi: 10.1038/msb.2009.2. Epub 2009 Feb 17. Erratum in: Mol Syst Biol. 2009;5:257.

27.

Predicting cellular growth from gene expression signatures.

Airoldi EM, Huttenhower C, Gresham D, Lu C, Caudy AA, Dunham MJ, Broach JR, Botstein D, Troyanskaya OG.

PLoS Comput Biol. 2009 Jan;5(1):e1000257. doi: 10.1371/journal.pcbi.1000257. Epub 2009 Jan 2.

28.

Microarray data mining: a novel optimization-based approach to uncover biologically coherent structures.

Tan MP, Smith EN, Broach JR, Floudas CA.

BMC Bioinformatics. 2008 Jun 6;9:268. doi: 10.1186/1471-2105-9-268.

29.

How Saccharomyces responds to nutrients.

Zaman S, Lippman SI, Zhao X, Broach JR.

Annu Rev Genet. 2008;42:27-81. doi: 10.1146/annurev.genet.41.110306.130206. Review.

PMID:
18303986
30.
31.

Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae.

Yorimitsu T, Zaman S, Broach JR, Klionsky DJ.

Mol Biol Cell. 2007 Oct;18(10):4180-9. Epub 2007 Aug 15.

32.

Sch9 is a major target of TORC1 in Saccharomyces cerevisiae.

Urban J, Soulard A, Huber A, Lippman S, Mukhopadhyay D, Deloche O, Wanke V, Anrather D, Ammerer G, Riezman H, Broach JR, De Virgilio C, Hall MN, Loewith R.

Mol Cell. 2007 Jun 8;26(5):663-74.

33.

Do cells think?

Ramanathan S, Broach JR.

Cell Mol Life Sci. 2007 Jul;64(14):1801-4. Review.

PMID:
17530173
34.

Cross-talk and decision making in MAP kinase pathways.

McClean MN, Mody A, Broach JR, Ramanathan S.

Nat Genet. 2007 Mar;39(3):409-14. Epub 2007 Jan 28. Erratum in: Nat Genet. 2007 Apr;39(4):567.

PMID:
17259986
36.

Single-cell observations reveal intermediate transcriptional silencing states.

Xu EY, Zawadzki KA, Broach JR.

Mol Cell. 2006 Jul 21;23(2):219-29.

37.

The dynamics of homologous pairing during mating type interconversion in budding yeast.

Houston PL, Broach JR.

PLoS Genet. 2006 Jun;2(6):e98. Epub 2006 Jun 23.

38.

Creation of GPCR-based chemical sensors by directed evolution in yeast.

Ault AD, Broach JR.

Protein Eng Des Sel. 2006 Jan;19(1):1-8. Epub 2005 Nov 1.

PMID:
16263727
39.

Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity.

Niida A, Wang Z, Tomita K, Oishi S, Tamamura H, Otaka A, Navenot JM, Broach JR, Peiper SC, Fujii N.

Bioorg Med Chem Lett. 2006 Jan 1;16(1):134-7. Epub 2005 Oct 18.

PMID:
16242330
40.

Mutations in the nucleosome core enhance transcriptional silencing.

Xu EY, Bi X, Holland MJ, Gottschling DE, Broach JR.

Mol Cell Biol. 2005 Mar;25(5):1846-59.

41.

Sense and sensibility: nutritional response and signal integration in yeast.

Schneper L, Düvel K, Broach JR.

Curr Opin Microbiol. 2004 Dec;7(6):624-30. Review.

PMID:
15556035
42.

Making the right choice--long-range chromosomal interactions in development.

Broach JR.

Cell. 2004 Nov 24;119(5):583-6. Review. Erratum in: Cell. 2004 Dec 29;119(7):1057.

43.

PP2A phosphatase activity is required for stress and Tor kinase regulation of yeast stress response factor Msn2p.

Santhanam A, Hartley A, Düvel K, Broach JR, Garrett S.

Eukaryot Cell. 2004 Oct;3(5):1261-71.

44.

A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size.

Jorgensen P, Rupes I, Sharom JR, Schneper L, Broach JR, Tyers M.

Genes Dev. 2004 Oct 15;18(20):2491-505. Epub 2004 Oct 1.

45.

Ras and Gpa2 mediate one branch of a redundant glucose signaling pathway in yeast.

Wang Y, Pierce M, Schneper L, Güldal CG, Zhang X, Tavazoie S, Broach JR.

PLoS Biol. 2004 May;2(5):E128. Epub 2004 May 11.

47.

Metastin and its variant forms suppress migration of pancreatic cancer cells.

Masui T, Doi R, Mori T, Toyoda E, Koizumi M, Kami K, Ito D, Peiper SC, Broach JR, Oishi S, Niida A, Fujii N, Imamura M.

Biochem Biophys Res Commun. 2004 Feb 27;315(1):85-92.

PMID:
15013429
48.
49.

Theoretical and computational studies of the glucose signaling pathways in yeast using global gene expression data.

Lin X, Floudas CA, Wang Y, Broach JR.

Biotechnol Bioeng. 2003 Dec 30;84(7):864-86.

PMID:
14708127
50.

The role of phosphatases in TOR signaling in yeast.

Düvel K, Broach JR.

Curr Top Microbiol Immunol. 2004;279:19-38. Review.

PMID:
14560949

Supplemental Content

Loading ...
Support Center