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Characterization of metastatic urothelial carcinoma via comprehensive genomic profiling of circulating tumor DNA.

Agarwal N, Pal SK, Hahn AW, Nussenzveig RH, Pond GR, Gupta SV, Wang J, Bilen MA, Naik G, Ghatalia P, Hoimes CJ, Gopalakrishnan D, Barata PC, Drakaki A, Faltas BM, Kiedrowski LA, Lanman RB, Nagy RJ, Vogelzang NJ, Boucher KM, Vaishampayan UN, Sonpavde G, Grivas P.

Cancer. 2018 Mar 8. doi: 10.1002/cncr.31314. [Epub ahead of print]


Combination of the low anticoagulant heparin CX-01 with chemotherapy for the treatment of acute myeloid leukemia.

Kovacsovics TJ, Mims A, Salama ME, Pantin J, Rao N, Kosak KM, Ahorukomeye P, Glenn MJ, Deininger MWN, Boucher KM, Bavisotto LM, Gutierrez-Sanchez G, Kennedy TP, Marcus SG, Shami PJ.

Blood Adv. 2018 Feb 27;2(4):381-389. doi: 10.1182/bloodadvances.2017013391.


Association of Sulindac and Erlotinib vs Placebo With Colorectal Neoplasia in Familial Adenomatous Polyposis: Secondary Analysis of a Randomized Clinical Trial.

Samadder NJ, Kuwada SK, Boucher KM, Byrne K, Kanth P, Samowitz W, Jones D, Tavtigian SV, Westover M, Berry T, Jasperson K, Pappas L, Smith L, Sample D, Burt RW, Neklason DW.

JAMA Oncol. 2018 Feb 8. doi: 10.1001/jamaoncol.2017.5431. [Epub ahead of print]


A statewide investigation of geographic lung cancer incidence patterns and radon exposure in a low-smoking population.

Ou JY, Fowler B, Ding Q, Kirchhoff AC, Pappas L, Boucher K, Akerley W, Wu Y, Kaphingst K, Harding G, Kepka D.

BMC Cancer. 2018 Jan 31;18(1):115. doi: 10.1186/s12885-018-4002-9.


p53 status in the primary tumor predicts efficacy of subsequent abiraterone and enzalutamide in castration-resistant prostate cancer.

Maughan BL, Guedes LB, Boucher K, Rajoria G, Liu Z, Klimek S, Zoino R, Antonarakis ES, Lotan TL.

Prostate Cancer Prostatic Dis. 2018 Jan 4. doi: 10.1038/s41391-017-0027-4. [Epub ahead of print]


Modeling the ACMG/AMP variant classification guidelines as a Bayesian classification framework.

Tavtigian SV, Greenblatt MS, Harrison SM, Nussbaum RL, Prabhu SA, Boucher KM, Biesecker LG.

Genet Med. 2018 Jan 4. doi: 10.1038/gim.2017.210. [Epub ahead of print]


The association between socioeconomic factors and breast cancer-specific survival varies by race.

Agarwal S, Ying J, Boucher KM, Agarwal JP.

PLoS One. 2017 Dec 6;12(12):e0187018. doi: 10.1371/journal.pone.0187018. eCollection 2017.


Overcoming resistance to single-agent therapy for oncogenic BRAF gene fusions via combinatorial targeting of MAPK and PI3K/mTOR signaling pathways.

Jain P, Silva A, Han HJ, Lang SS, Zhu Y, Boucher K, Smith TE, Vakil A, Diviney P, Choudhari N, Raman P, Busch CM, Delaney T, Yang X, Olow AK, Mueller S, Haas-Kogan D, Fox E, Storm PB, Resnick AC, Waanders AJ.

Oncotarget. 2017 Sep 15;8(49):84697-84713. doi: 10.18632/oncotarget.20949. eCollection 2017 Oct 17.


Chemoprevention with Cyclooxygenase and Epidermal Growth Factor Receptor Inhibitors in Familial Adenomatous Polyposis Patients: mRNA Signatures of Duodenal Neoplasia.

Delker DA, Wood AC, Snow AK, Samadder NJ, Samowitz WS, Affolter KE, Boucher KM, Pappas LM, Stijleman IJ, Kanth P, Byrne KR, Burt RW, Bernard PS, Neklason DW.

Cancer Prev Res (Phila). 2018 Jan;11(1):4-15. doi: 10.1158/1940-6207.CAPR-17-0130. Epub 2017 Nov 6.


A novel educational intervention targeting melanoma risk and prevention knowledge among children with a familial risk for melanoma.

Wu YP, Nagelhout E, Aspinwall LG, Boucher KM, Parsons BG, Kohlmann W, Kaphingst KA, Homburger S, Perkins RD, Grossman D, Harding G, Leachman SA.

Patient Educ Couns. 2018 Mar;101(3):452-459. doi: 10.1016/j.pec.2017.10.008. Epub 2017 Oct 19.


Comprehensive Genomic Sequencing of Urothelial Tumors Identifies Rare SMARCB1 (INI-1)-Deficient Carcinomas of the Urinary System.

Gupta S, Albertson D, Gaston D, Heilbrun ME, Agarwal N, Boucher K, Parnell TJ, Liu T, Morgans A, Madison R, Gowen K, Miller VA, Ross JS, Ali SM, Millis SZ.

Clin Genitourin Cancer. 2017 Sep 7. pii: S1558-7673(17)30276-8. doi: 10.1016/j.clgc.2017.09.001. [Epub ahead of print]


Incidence and Characterization of Antiandrogen Withdrawal Syndrome After Discontinuation of Treatment With Enzalutamide in Castration-resistant Prostate Cancer.

Poole A, Gill D, Hahn AW, Johnson E, Carroll E, Boucher K, Nussenzveig R, Maughan B, Agarwal N.

Clin Genitourin Cancer. 2017 Sep 6. pii: S1558-7673(17)30272-0. doi: 10.1016/j.clgc.2017.08.017. [Epub ahead of print]


Risk factors for development of melanoma brain metastasis and disease progression: a single-center retrospective analysis.

Gardner LJ, Ward M, Andtbacka RHI, Boucher KM, Bowen GM, Bowles TL, Cohen AL, Grossmann K, Hitchcock YJ, Holmen SL, Hyngstrom J, Khong H, McMahon M, Monroe MM, Ross CB, Suneja G, Wada D, Grossman D.

Melanoma Res. 2017 Oct;27(5):477-484. doi: 10.1097/CMR.0000000000000382.


Cancer Risk in Families Fulfilling the Amsterdam Criteria for Lynch Syndrome.

Samadder NJ, Smith KR, Wong J, Thomas A, Hanson H, Boucher K, Kopituch C, Cannon-Albright LA, Burt RW, Curtin K.

JAMA Oncol. 2017 Dec 1;3(12):1697-1701. doi: 10.1001/jamaoncol.2017.0769.


Can I Work with and Help Others in This Field? How Communal Goals Influence Interest and Participation in STEM Fields.

Boucher KL, Fuesting MA, Diekman AB, Murphy MC.

Front Psychol. 2017 May 31;8:901. doi: 10.3389/fpsyg.2017.00901. eCollection 2017. Review.


Diverse Non-genetic, Allele-Specific Expression Effects Shape Genetic Architecture at the Cellular Level in the Mammalian Brain.

Huang WC, Ferris E, Cheng T, Hörndli CS, Gleason K, Tamminga C, Wagner JD, Boucher KM, Christian JL, Gregg C.

Neuron. 2017 Mar 8;93(5):1094-1109.e7. doi: 10.1016/j.neuron.2017.01.033. Epub 2017 Feb 23.


Implications of inaccurate clinical nodal staging in pancreatic adenocarcinoma.

Swords DS, Firpo MA, Johnson KM, Boucher KM, Scaife CL, Mulvihill SJ.

Surgery. 2017 Jul;162(1):104-111. doi: 10.1016/j.surg.2016.12.029. Epub 2017 Feb 21.


The BREASTrial Stage II: ADM Breast Reconstruction Outcomes from Definitive Reconstruction to 3 Months Postoperative.

Mendenhall SD, Anderson LA, Ying J, Boucher KM, Neumayer LA, Agarwal JP.

Plast Reconstr Surg Glob Open. 2017 Jan 25;5(1):e1209. doi: 10.1097/GOX.0000000000001209. eCollection 2017 Jan.


Efficacy of Eplerenone in the Management of Mineralocorticoid Excess in Men With Metastatic Castration-resistant Prostate Cancer Treated With Abiraterone Without Prednisone.

Gill D, Gaston D, Bailey E, Hahn A, Gupta S, Batten J, Alex A, Boucher K, Stenehjem D, Agarwal N.

Clin Genitourin Cancer. 2017 Aug;15(4):e599-e602. doi: 10.1016/j.clgc.2016.12.008. Epub 2017 Jan 5.


Colorectal Cancer in Inflammatory Bowel Diseases: A Population-Based Study in Utah.

Jewel Samadder N, Valentine JF, Guthery S, Singh H, Bernstein CN, Wan Y, Wong J, Boucher K, Pappas L, Rowe K, Bronner M, Ulrich CM, Burt RW, Curtin K, Smith KR.

Dig Dis Sci. 2017 Aug;62(8):2126-2132. doi: 10.1007/s10620-016-4435-4. Epub 2017 Jan 3.


A Phase II Randomized Placebo-Controlled Trial of Oral N-acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress In Vivo.

Cassidy PB, Liu T, Florell SR, Honeggar M, Leachman SA, Boucher KM, Grossman D.

Cancer Prev Res (Phila). 2017 Jan;10(1):36-44. doi: 10.1158/1940-6207.CAPR-16-0162. Epub 2016 Dec 5.


POWERPIINC (PreOperative Window of Endocrine TheRapy Provides Information to Increase Compliance) trial: Changes in tumor proliferation index and quality of life with 7 days of preoperative tamoxifen.

Cohen AL, Factor RE, Mooney K, Salama ME, Wade M, Serpico V, Ostrander E, Nelson E, Porretta J, Matsen C, Bernard P, Boucher K, Neumayer L.

Breast. 2017 Feb;31:219-223. doi: 10.1016/j.breast.2016.11.016. Epub 2016 Dec 6.


Long-term health effects among testicular cancer survivors.

Hashibe M, Abdelaziz S, Al-Temimi M, Fraser A, Boucher KM, Smith K, Lee YA, Rowe K, Rowley B, Daurelle M, Holton AE, VanDerslice J, Richiardi L, Bishoff J, Lowrance W, Stroup A.

J Cancer Surviv. 2016 Dec;10(6):1051-1057. Epub 2016 May 11.


Familial Risk of Biliary Tract Cancers: A Population-Based Study in Utah.

Samadder NJ, Smith KR, Wong J, Hanson H, Boucher K, Burt RW, Charlton M, Byrne KR, Gallegos-Orozco JF, Koptiuch C, Curtin K.

Dig Dis Sci. 2016 Dec;61(12):3627-3632. Epub 2016 Sep 21.


Factors associated with early adoption of the HPV vaccine in US male adolescents include Hispanic ethnicity and receipt of other vaccines.

Kepka D, Ding Q, Hawkins AJ, Warner EL, Boucher KM.

Prev Med Rep. 2016 May 25;4:98-102. doi: 10.1016/j.pmedr.2016.05.014. eCollection 2016 Dec.


The Effect of Previsit Education in Breast Cancer Patients: A Study of a Shared-decision-making Tool.

Serpico V, Liepert AE, Boucher K, Fouts DL, Anderson L, Pell J, Neumayer L.

Am Surg. 2016 Mar;82(3):259-65.


Gene Signature in Sessile Serrated Polyps Identifies Colon Cancer Subtype.

Kanth P, Bronner MP, Boucher KM, Burt RW, Neklason DW, Hagedorn CH, Delker DA.

Cancer Prev Res (Phila). 2016 Jun;9(6):456-65. doi: 10.1158/1940-6207.CAPR-15-0363. Epub 2016 Mar 29.


Effect of Sulindac and Erlotinib vs Placebo on Duodenal Neoplasia in Familial Adenomatous Polyposis: A Randomized Clinical Trial.

Samadder NJ, Neklason DW, Boucher KM, Byrne KR, Kanth P, Samowitz W, Jones D, Tavtigian SV, Done MW, Berry T, Jasperson K, Pappas L, Smith L, Sample D, Davis R, Topham MK, Lynch P, Strait E, McKinnon W, Burt RW, Kuwada SK.

JAMA. 2016 Mar 22-29;315(12):1266-75. doi: 10.1001/jama.2016.2522.


Reduction in nevus biopsies in patients monitored by total body photography.

Truong A, Strazzulla L, March J, Boucher KM, Nelson KC, Kim CC, Grossman D.

J Am Acad Dermatol. 2016 Jul;75(1):135-143.e5. doi: 10.1016/j.jaad.2016.02.1152. Epub 2016 Mar 3.


Increased dietary vitamin K intake is associated with less severe subjective memory complaint among older adults.

Soutif-Veillon A, Ferland G, Rolland Y, Presse N, Boucher K, Féart C, Annweiler C.

Maturitas. 2016 Nov;93:131-136. doi: 10.1016/j.maturitas.2016.02.004. Epub 2016 Feb 11.


Phase II study of amrubicin (SM-5887), a synthetic 9-aminoanthracycline, as first line treatment in patients with metastatic or unresectable soft tissue sarcoma: durable response in myxoid liposarcoma with TLS-CHOP translocation.

Gupta S, Gouw L, Wright J, Chawla S, Pitt D, Wade M, Boucher K, Sharma S.

Invest New Drugs. 2016 Apr;34(2):243-52. doi: 10.1007/s10637-016-0333-z. Epub 2016 Feb 20.


Familial Risk in Patients With Carcinoma of Unknown Primary.

Samadder NJ, Smith KR, Hanson H, Pimentel R, Wong J, Boucher K, Akerley W, Gilcrease G, Ulrich CM, Burt RW, Curtin K.

JAMA Oncol. 2016 Mar;2(3):340-6. doi: 10.1001/jamaoncol.2015.4265.


MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.

Bandopadhayay P, Ramkissoon LA, Jain P, Bergthold G, Wala J, Zeid R, Schumacher SE, Urbanski L, O'Rourke R, Gibson WJ, Pelton K, Ramkissoon SH, Han HJ, Zhu Y, Choudhari N, Silva A, Boucher K, Henn RE, Kang YJ, Knoff D, Paolella BR, Gladden-Young A, Varlet P, Pages M, Horowitz PM, Federation A, Malkin H, Tracy AA, Seepo S, Ducar M, Van Hummelen P, Santi M, Buccoliero AM, Scagnet M, Bowers DC, Giannini C, Puget S, Hawkins C, Tabori U, Klekner A, Bognar L, Burger PC, Eberhart C, Rodriguez FJ, Hill DA, Mueller S, Haas-Kogan DA, Phillips JJ, Santagata S, Stiles CD, Bradner JE, Jabado N, Goren A, Grill J, Ligon AH, Goumnerova L, Waanders AJ, Storm PB, Kieran MW, Ligon KL, Beroukhim R, Resnick AC.

Nat Genet. 2016 Mar;48(3):273-82. doi: 10.1038/ng.3500. Epub 2016 Feb 1.


Conditional survival for pediatric and adolescent patients with cancer: Implications for survivorship care.

Kaul S, Kirchhoff AC, Boucher KM, Dietz AC.

Cancer Epidemiol. 2015 Dec;39(6):1071-7. doi: 10.1016/j.canep.2015.09.006. Epub 2015 Oct 1.


ReCAP: Gaps in Insurance Coverage for Pediatric Patients With Acute Lymphoblastic Leukemia.

Smits-Seemann RR, Kaul S, Hersh AO, Fluchel MN, Boucher KM, Kirchhoff AC, Smits-Seemann RR, Kaul S, Hersh AO, Fluchel MN, Boucher KM, Kirchhoff AC.

J Oncol Pract. 2016 Feb;12(2):175-6; e207-14. doi: 10.1200/JOP.2015.005686. Epub 2015 Sep 29.


The BREASTrial Stage II: ADM Breast Reconstruction Outcomes from the Time of Implant Exchange to 3 Months Post-Op.

Mendenhall SD, Anderson LA, Ying J, Boucher KM, Neumayer LA, Agarwal JP.

Plast Reconstr Surg. 2015 Oct;136(4 Suppl):111-2. doi: 10.1097/01.prs.0000472418.74056.f3. No abstract available.


A pilot study of JI-101, an inhibitor of VEGFR-2, PDGFR-β, and EphB4 receptors, in combination with everolimus and as a single agent in an ovarian cancer expansion cohort.

Werner TL, Wade ML, Agarwal N, Boucher K, Patel J, Luebke A, Sharma S.

Invest New Drugs. 2015 Dec;33(6):1217-24. doi: 10.1007/s10637-015-0288-5. Epub 2015 Sep 14.


Risk of Incident Colorectal Cancer and Death After Colonoscopy: A Population-based Study in Utah.

Samadder NJ, Curtin K, Pappas L, Boucher K, Mineau GP, Smith K, Fraser A, Wan Y, Provenzale D, Kinney AY, Ulrich C, Burt RW.

Clin Gastroenterol Hepatol. 2016 Feb;14(2):279-86.e1-2. doi: 10.1016/j.cgh.2015.08.033. Epub 2015 Sep 4.


FDG and FLT-PET for Early measurement of response to 37.5 mg daily sunitinib therapy in metastatic renal cell carcinoma.

Horn KP, Yap JT, Agarwal N, Morton KA, Kadrmas DJ, Beardmore B, Butterfield RI, Boucher K, Hoffman JM.

Cancer Imaging. 2015 Sep 3;15:15. doi: 10.1186/s40644-015-0049-x.


Dietary Vitamin K Intake Is Associated with Cognition and Behaviour among Geriatric Patients: The CLIP Study.

Chouet J, Ferland G, Féart C, Rolland Y, Presse N, Boucher K, Barberger-Gateau P, Beauchet O, Annweiler C.

Nutrients. 2015 Aug 12;7(8):6739-50. doi: 10.3390/nu7085306.


Increased Risk of Colorectal Cancer Among Family Members of All Ages, Regardless of Age of Index Case at Diagnosis.

Samadder NJ, Smith KR, Hanson H, Pimentel R, Wong J, Boucher K, Ahnen D, Singh H, Ulrich CM, Burt RW, Curtin K.

Clin Gastroenterol Hepatol. 2015 Dec;13(13):2305-11.e1-2. doi: 10.1016/j.cgh.2015.06.040. Epub 2015 Jul 16.


Efficacy of a Telehealth Intervention on Colonoscopy Uptake When Cost Is a Barrier: The Family CARE Cluster Randomized Controlled Trial.

Steffen LE, Boucher KM, Damron BH, Pappas LM, Walters ST, Flores KG, Boonyasiriwat W, Vernon SW, Stroup AM, Schwartz MD, Edwards SL, Kohlmann WK, Lowery JT, Wiggins CL, Hill DA, Higginbotham JC, Burt R, Simmons RG, Kinney AY.

Cancer Epidemiol Biomarkers Prev. 2015 Sep;24(9):1311-8. doi: 10.1158/1055-9965.EPI-15-0150. Epub 2015 Jun 22.


Phase I trial of low-dose oral Clofarabine in myelodysplastic syndromes patients who have failed frontline therapy.

Rudrapatna VK, Morley K, Boucher KM, Pierson AS, Shull CT, Kushner JP, Shami PJ.

Leuk Res. 2015 Aug;39(8):835-9. doi: 10.1016/j.leukres.2015.05.004. Epub 2015 May 18.


The Effect of Radiation on Complication Rates and Patient Satisfaction in Breast Reconstruction using Temporary Tissue Expanders and Permanent Implants.

Anker CJ, Hymas RV, Ahluwalia R, Kokeny KE, Avizonis V, Boucher KM, Neumayer LA, Agarwal JP.

Breast J. 2015 May-Jun;21(3):233-40. doi: 10.1111/tbj.12395. Epub 2015 Mar 15.


Clinical outcomes associated with evolving treatment modalities and radiation techniques for base-of-tongue carcinoma: thirty years of institutional experience.

Chen LA, Anker CJ, Hunt JP, Buchmann LO, Grossmann KF, Boucher K, Fang LM, Shrieve DC, Hitchcock YJ.

Cancer Med. 2015 May;4(5):651-60. doi: 10.1002/cam4.364. Epub 2015 Jan 26.


Familial colorectal cancer risk by subsite of primary cancer: a population-based study in Utah.

Samadder NJ, Smith KR, Mineau GP, Pimentel R, Wong J, Boucher K, Pappas L, Singh H, Ahnen D, Burt RW, Curtin K.

Aliment Pharmacol Ther. 2015 Mar;41(6):573-80. doi: 10.1111/apt.13086. Epub 2015 Jan 21.


Toxicity and cost-effectiveness analysis of intensity modulated radiation therapy versus 3-dimensional conformal radiation therapy for postoperative treatment of gynecologic cancers.

Chen LA, Kim J, Boucher K, Terakedis B, Williams B, Nickman NA, Gaffney DK.

Gynecol Oncol. 2015 Mar;136(3):521-8. doi: 10.1016/j.ygyno.2014.12.039. Epub 2015 Jan 3.


The BREASTrial: stage I. Outcomes from the time of tissue expander and acellular dermal matrix placement to definitive reconstruction.

Mendenhall SD, Anderson LA, Ying J, Boucher KM, Liu T, Neumayer LA, Agarwal JP.

Plast Reconstr Surg. 2015 Jan;135(1):29e-42e. doi: 10.1097/PRS.0000000000000758.


The breast reconstruction evaluation of acellular dermal matrix as a sling trial (BREASTrial): design and methods of a prospective randomized trial.

Agarwal JP, Mendenhall SD, Anderson LA, Ying J, Boucher KM, Liu T, Neumayer LA.

Plast Reconstr Surg. 2015 Jan;135(1):20e-8e. doi: 10.1097/PRS.0000000000000809.


Expanding access to BRCA1/2 genetic counseling with telephone delivery: a cluster randomized trial.

Kinney AY, Butler KM, Schwartz MD, Mandelblatt JS, Boucher KM, Pappas LM, Gammon A, Kohlmann W, Edwards SL, Stroup AM, Buys SS, Flores KG, Campo RA.

J Natl Cancer Inst. 2014 Nov 5;106(12). pii: dju328. doi: 10.1093/jnci/dju328. Print 2014 Dec.

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