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Items: 1 to 50 of 57

1.

PTEN decreases in vivo vascularization of experimental gliomas in spite of proangiogenic stimuli.

Abe T, Terada K, Wakimoto H, Inoue R, Tyminski E, Bookstein R, Basilion JP, Chiocca EA.

Cancer Res. 2003 May 1;63(9):2300-5.

2.

The product of the candidate prostate cancer susceptibility gene ELAC2 interacts with the gamma-tubulin complex.

Korver W, Guevara C, Chen Y, Neuteboom S, Bookstein R, Tavtigian S, Lees E.

Int J Cancer. 2003 Apr 10;104(3):283-8.

3.

Restoration of transforming growth factor Beta signaling by functional expression of smad4 induces anoikis.

Ramachandra M, Atencio I, Rahman A, Vaillancourt M, Zou A, Avanzini J, Wills K, Bookstein R, Shabram P.

Cancer Res. 2002 Nov 1;62(21):6045-51.

4.

Enhanced sensitivity of multiple myeloma cells containing PTEN mutations to CCI-779.

Shi Y, Gera J, Hu L, Hsu JH, Bookstein R, Li W, Lichtenstein A.

Cancer Res. 2002 Sep 1;62(17):5027-34.

5.

Intra-arterial delivery of p53-containing adenoviral vector into experimental brain tumors.

Abe T, Wakimoto H, Bookstein R, Maneval DC, Chiocca EA, Basilion JP.

Cancer Gene Ther. 2002 Mar;9(3):228-35.

6.

Evaluation of endostatin antiangiogenesis gene therapy in vitro and in vivo.

Jin X, Bookstein R, Wills K, Avanzini J, Tsai V, LaFace D, Terracina G, Shi B, Nielsen LL.

Cancer Gene Ther. 2001 Dec;8(12):982-9.

7.

PTEN expression is maintained in sporadic colorectal tumours.

Taniyama K, Goodison S, Ito R, Bookstein R, Miyoshi N, Tahara E, Tarin D, Urquidi V.

J Pathol. 2001 Jul;194(3):341-8.

PMID:
11439367
8.

The tumor suppressor PTEN negatively regulates insulin signaling in 3T3-L1 adipocytes.

Nakashima N, Sharma PM, Imamura T, Bookstein R, Olefsky JM.

J Biol Chem. 2000 Apr 28;275(17):12889-95.

9.

Adenovirus-mediated gene transfer of MMAC1/PTEN to glioblastoma cells inhibits S phase entry by the recruitment of p27Kip1 into cyclin E/CDK2 complexes.

Cheney IW, Neuteboom ST, Vaillancourt MT, Ramachandra M, Bookstein R.

Cancer Res. 1999 May 15;59(10):2318-23.

10.

Phenotypic analysis of human glioma cells expressing the MMAC1 tumor suppressor phosphatase.

Morimoto AM, Berson AE, Fujii GH, Teng DH, Tavtigian SV, Bookstein R, Steck PA, Bolen JB.

Oncogene. 1999 Feb 11;18(6):1261-6.

11.

In vivo tumor suppression by adenovirus-mediated interferon alpha2b gene delivery.

Ahmed CM, Sugarman BJ, Johnson DE, Bookstein RE, Saha DP, Nagabhushan TL, Wills KN.

Hum Gene Ther. 1999 Jan 1;10(1):77-84.

PMID:
10022532
12.

High-density screen of human tumor cell lines for homozygous deletions of loci on chromosome arm 8p.

Levy A, Dang UC, Bookstein R.

Genes Chromosomes Cancer. 1999 Jan;24(1):42-7.

PMID:
9892107
13.

Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis.

Davies MA, Lu Y, Sano T, Fang X, Tang P, LaPushin R, Koul D, Bookstein R, Stokoe D, Yung WK, Mills GB, Steck PA.

Cancer Res. 1998 Dec 1;58(23):5285-90. Erratum in: Cancer Res 1999 Mar 1;59(5):1167.

14.

Suppression of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer.

Cheney IW, Johnson DE, Vaillancourt MT, Avanzini J, Morimoto A, Demers GW, Wills KN, Shabram PW, Bolen JB, Tavtigian SV, Bookstein R.

Cancer Res. 1998 Jun 1;58(11):2331-4.

15.

Engineered mutants of pRB with improved growth suppression potential.

Antelman D, Perry S, Hollingsworth R, Gregory RJ, Driscoll B, Fung YK, Bookstein R.

Oncogene. 1997 Dec 4;15(23):2855-66.

16.

Comparative mutational analysis of DPC4 (Smad4) in prostatic and colorectal carcinomas.

MacGrogan D, Pegram M, Slamon D, Bookstein R.

Oncogene. 1997 Aug 28;15(9):1111-4.

17.

Tumour-suppressor genes in prostatic oncogenesis: a positional approach.

Bookstein R, Bova GS, MacGrogan D, Levy A, Isaacs WB.

Br J Urol. 1997 Mar;79 Suppl 1:28-36. Review.

PMID:
9088270
18.

Tumour suppressor genes in prostate cancer.

MacGrogan D, Bookstein R.

Semin Cancer Biol. 1997 Feb;8(1):11-9. Review.

PMID:
9299577
19.

Structure and methylation-associated silencing of a gene within a homozygously deleted region of human chromosome band 8p22.

MacGrogan D, Levy A, Bova GS, Isaacs WB, Bookstein R.

Genomics. 1996 Jul 1;35(1):55-65.

PMID:
8661104
20.

Physical mapping of chromosome 8p22 markers and their homozygous deletion in a metastatic prostate cancer.

Bova GS, MacGrogan D, Levy A, Pin SS, Bookstein R, Isaacs WB.

Genomics. 1996 Jul 1;35(1):46-54.

PMID:
8661103
21.

p53 gene therapy in vivo of herpatocellular and liver metastatic colorectal cancer.

Bookstein R, Demers W, Gregory R, Maneval D, Park J, Wills K.

Semin Oncol. 1996 Feb;23(1):66-77. Review.

PMID:
8607033
22.

Report and abstracts of the second international workshop on human chromosome 8 mapping 1994. Oxford, United Kingdom, September 16-18, 1994.

Spurr NK, Blanton S, Bookstein R, Clarke R, Cottingham R, Daiger S, Drayna D, Faber P, Horrigan S, Kas K, et al.

Cytogenet Cell Genet. 1995;68(3-4):147-64. No abstract available.

PMID:
7842731
23.

Yeast artificial chromosome and radiation hybrid map of loci in chromosome band 8p22, a common region of allelic loss in multiple human cancers.

Bookstein R, Levy A, MacGrogan D, Lewis TB, Weissenbach J, O'Connell P, Leach RJ.

Genomics. 1994 Nov 15;24(2):317-23.

PMID:
7698754
24.

Comparative genomic hybridization, allelic imbalance, and fluorescence in situ hybridization on chromosome 8 in prostate cancer.

Cher ML, MacGrogan D, Bookstein R, Brown JA, Jenkins RB, Jensen RH.

Genes Chromosomes Cancer. 1994 Nov;11(3):153-62.

PMID:
7530484
25.

Loss of chromosome arm 8p loci in prostate cancer: mapping by quantitative allelic imbalance.

MacGrogan D, Levy A, Bostwick D, Wagner M, Wells D, Bookstein R.

Genes Chromosomes Cancer. 1994 Jul;10(3):151-9.

PMID:
7522037
26.

Tumor suppressor genes in prostatic oncogenesis.

Bookstein R.

J Cell Biochem Suppl. 1994;19:217-23. Review.

PMID:
7823594
27.

The most promising surrogate endpoint biomarkers for screening candidate chemopreventive compounds for prostatic adenocarcinoma in short-term phase II clinical trials.

Bostwick DG, Burke HB, Wheeler TM, Chung LW, Bookstein R, Pretlow TG, Nagle RB, Montironi R, Lieber MM, Veltri RW, et al.

J Cell Biochem Suppl. 1994;19:283-9. Review.

PMID:
7529857
28.

p53 is mutated in a subset of advanced-stage prostate cancers.

Bookstein R, MacGrogan D, Hilsenbeck SG, Sharkey F, Allred DC.

Cancer Res. 1993 Jul 15;53(14):3369-73.

29.

Recessive oncogenes.

Bookstein R, Allred DC.

Cancer. 1993 Feb 1;71(3 Suppl):1179-86.

PMID:
8428341
30.

Report and abstracts of the First International Workshop on Human Chromosome 8 Mapping. Vancouver, British Columbia, May 2-4, 1993.

Wood S, Ben Othmane K, Bergerheim US, Blanton SH, Bookstein R, Clarke RA, Daiger SP, Donis-Keller H, Drayna D, Kumar S, et al.

Cytogenet Cell Genet. 1993;64(3-4):134-46. No abstract available.

PMID:
8404033
31.

Stability of retinoblastoma gene expression determines the tumorigenicity of reconstituted retinoblastoma cells.

Chen PL, Chen Y, Shan B, Bookstein R, Lee WH.

Cell Growth Differ. 1992 Feb;3(2):119-25.

32.

Retinoblastoma cell lines Y79, RB355 and WERI-Rb27 are genetically related.

Madreperla SA, Bookstein R, Jones OW, Lee WH.

Ophthalmic Paediatr Genet. 1991 Mar;12(1):49-56.

PMID:
1679230
33.

Molecular genetics of the retinoblastoma suppressor gene.

Bookstein R, Lee WH.

Crit Rev Oncog. 1991;2(3):211-27. Review.

PMID:
1888791
34.

Role of the retinoblastoma gene in the oncogenesis of human breast carcinoma.

Lee EY, Bookstein R, Lee WH.

Cancer Treat Res. 1991;53:23-44. Review. No abstract available.

PMID:
1672079
35.

Genetic mechanisms of tumor suppression by the human p53 gene.

Chen PL, Chen YM, Bookstein R, Lee WH.

Science. 1990 Dec 14;250(4987):1576-80.

PMID:
2274789
36.

Resolution of DNA linkage discrepancies through analysis of a VNTR locus in a family study of cystic fibrosis.

Cahill TC, Bookstein R, Axelrod F, Ngo KY, Scioscia AL.

Prenat Diagn. 1990 Dec;10(12):795-9.

PMID:
2075181
37.

Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma.

Bookstein R, Rio P, Madreperla SA, Hong F, Allred C, Grizzle WE, Lee WH.

Proc Natl Acad Sci U S A. 1990 Oct;87(19):7762-6.

38.

Characteristics of two new retinoblastoma cell lines: WERI-Rb24 and WERI-Rb27.

Sery TW, Lee EY, Lee WH, Bookstein R, Wong V, Shields JA, Augsburger JJ, Donoso LA.

J Pediatr Ophthalmol Strabismus. 1990 Jul-Aug;27(4):212-7.

PMID:
2391623
39.

PCR-based detection of a polymorphic BamHI site in intron 1 of the human retinoblastoma (RB) gene.

Bookstein R, Lai CC, To H, Lee WH.

Nucleic Acids Res. 1990 Mar 25;18(6):1666. No abstract available.

40.

Research with fetal tissue.

Bookstein R.

Nature. 1990 Mar 22;344(6264):284. No abstract available.

PMID:
2314466
41.

Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene.

Bookstein R, Shew JY, Chen PL, Scully P, Lee WH.

Science. 1990 Feb 9;247(4943):712-5.

PMID:
2300823
42.

Molecular biology of the human retinoblastoma gene.

Lee WH, Bookstein RE, Lee EY.

Immunol Ser. 1990;51:169-200. Review. No abstract available.

PMID:
1965700
43.
44.

Structure of the human retinoblastoma gene.

Hong FD, Huang HJ, To H, Young LJ, Oro A, Bookstein R, Lee EY, Lee WH.

Proc Natl Acad Sci U S A. 1989 Jul;86(14):5502-6.

45.
46.

Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells.

Huang HJ, Yee JK, Shew JY, Chen PL, Bookstein R, Friedmann T, Lee EY, Lee WH.

Science. 1988 Dec 16;242(4885):1563-6.

PMID:
3201247
47.

Studies on the human retinoblastoma susceptibility gene.

Lee WH, Bookstein R, Lee EY.

J Cell Biochem. 1988 Nov;38(3):213-27. Review.

PMID:
3068232
48.

Molecular mechanism of retinoblastoma gene inactivation in retinoblastoma cell line Y79.

Lee EY, Bookstein R, Young LJ, Lin CJ, Rosenfeld MG, Lee WH.

Proc Natl Acad Sci U S A. 1988 Aug;85(16):6017-21.

49.

Inactivation of the retinoblastoma susceptibility gene in human breast cancers.

Lee EY, To H, Shew JY, Bookstein R, Scully P, Lee WH.

Science. 1988 Jul 8;241(4862):218-21.

PMID:
3388033
50.

Human esterase D gene: complete cDNA sequence, genomic structure, and application in the genetic diagnosis of human retinoblastoma.

Young LJ, Lee EY, To HA, Bookstein R, Shew JY, Donoso LA, Sery T, Giblin M, Shields JA, Lee WH.

Hum Genet. 1988 Jun;79(2):137-41.

PMID:
3164702

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