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Risk of fall in patients with COPD.

Hakamy A, Bolton CE, Gibson JE, McKeever TM.

Thorax. 2018 Mar 21. pii: thoraxjnl-2017-211008. doi: 10.1136/thoraxjnl-2017-211008. [Epub ahead of print]


Variation in lung function and alterations in cardiac structure and function-Analysis of the UK Biobank cardiovascular magnetic resonance imaging substudy.

Thomson RJ, Aung N, Sanghvi MM, Paiva JM, Lee AM, Zemrak F, Fung K, Pfeffer PE, Mackay AJ, McKeever TM, Lukaschuk E, Carapella V, Kim YJ, Bolton CE, Piechnik SK, Neubauer S, Petersen SE.

PLoS One. 2018 Mar 20;13(3):e0194434. doi: 10.1371/journal.pone.0194434. eCollection 2018.


COPD exacerbations: transforming outcomes through research.

Hurst JR, Bafadhel M, Bolton CE, Quint JK, Sapey E, Wilkinson TMA.

Lancet Respir Med. 2018 Mar;6(3):172-174. doi: 10.1016/S2213-2600(18)30049-3. Epub 2018 Feb 9. No abstract available.


Rapid HIV disease progression following superinfection in an HLA-B*27:05/B*57:01-positive transmission recipient.

Brener J, Gall A, Hurst J, Batorsky R, Lavandier N, Chen F, Edwards A, Bolton C, Dsouza R, Allen T, Pybus OG, Kellam P, Matthews PC, Goulder PJR.

Retrovirology. 2018 Jan 16;15(1):7. doi: 10.1186/s12977-018-0390-9.


The recording and characteristics of pulmonary rehabilitation in patients with COPD using The Health Information Network (THIN) primary care database.

Hakamy A, McKeever TM, Gibson JE, Bolton CE.

NPJ Prim Care Respir Med. 2017 Oct 11;27(1):58. doi: 10.1038/s41533-017-0058-2.


Autoantibodies of IgM and IgG classes show differences in recognition of multiple autoantigens in chronic obstructive pulmonary disease.

Shindi R, Almehairi A, Negm OH, Kalsheker N, Gale NS, Shale DJ, Harrison TW, Bolton CE, John M, Todd I, Tighe PJ, Fairclough LC.

Clin Immunol. 2017 Oct;183:344-353. doi: 10.1016/j.clim.2017.09.020. Epub 2017 Sep 23.


The use of the practice walk test in pulmonary rehabilitation program: National COPD Audit Pulmonary Rehabilitation Workstream.

Hakamy A, McKeever TM, Steiner MC, Roberts CM, Singh SJ, Bolton CE.

Int J Chron Obstruct Pulmon Dis. 2017 Sep 8;12:2681-2686. doi: 10.2147/COPD.S141620. eCollection 2017.


Nonadherence to antiretroviral therapy among HIV-infected patients in Zambia is concentrated among a minority of patients and is highly variable across clinics.

Czaicki NL, Holmes CB, Sikazwe I, Bolton C, Savory T, Wa Mwanza M, Moyo C, Padian NS, Geng EH.

AIDS. 2017 Mar 13;31(5):689-696. doi: 10.1097/QAD.0000000000001347.


Socioeconomic deprivation and the outcome of pulmonary rehabilitation in England and Wales.

Steiner MC, Lowe D, Beckford K, Blakey J, Bolton CE, Elkin S, Man WD, Roberts CM, Sewell L, Walker P, Singh SJ.

Thorax. 2017 Jun;72(6):530-537. doi: 10.1136/thoraxjnl-2016-209376. Epub 2017 Jan 11.


The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production In Vitro.

Miller S, Henry AP, Hodge E, Kheirallah AK, Billington CK, Rimington TL, Bhaker SK, Obeidat M, Melén E, Merid SK, Swan C, Gowland C, Nelson CP, Stewart CE, Bolton CE, Kilty I, Malarstig A, Parker SG, Moffatt MF, Wardlaw AJ, Hall IP, Sayers I.

PLoS One. 2016 Oct 18;11(10):e0164041. doi: 10.1371/journal.pone.0164041. eCollection 2016.


AO pelvic fracture classification: can an educational package improve orthopaedic registrar performance?

Au J, Perriman DM, Bolton C, Abbott L, Neeman T, Smith PN.

ANZ J Surg. 2016 Dec;86(12):1019-1023. doi: 10.1111/ans.13761. Epub 2016 Sep 14.


Cardiovascular disease in COPD: time to quash a silent killer.

Bolton CE, Quint JK, Dransfield MT.

Lancet Respir Med. 2016 Sep;4(9):687-689. doi: 10.1016/S2213-2600(16)30243-0. No abstract available.


Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease.

Huang JT, Bolton CE, Miller BE, Tal-Singer R, Rabinovich RA, Palmer CN, Thomson NC, MacNee W; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators.

Eur Respir J. 2016 Oct;48(4):1215-1218. doi: 10.1183/13993003.01125-2016. Epub 2016 Sep 1. No abstract available.


Multiple Circulating Cytokines Are Coelevated in Chronic Obstructive Pulmonary Disease.

Selvarajah S, Todd I, Tighe PJ, John M, Bolton CE, Harrison T, Fairclough LC.

Mediators Inflamm. 2016;2016:3604842. doi: 10.1155/2016/3604842. Epub 2016 Jul 25.


The effect of pulmonary rehabilitation on mortality, balance, and risk of fall in stable patients with chronic obstructive pulmonary disease.

Hakamy A, Bolton CE, McKeever TM.

Chron Respir Dis. 2017 Feb;14(1):54-62. doi: 10.1177/1479972316661925. Epub 2016 Jan 1. Review.


Optimising prescription and titration of oxygen for adult inpatients using novel silicone wristbands: results of a pilot project at three centres.

Forster S, Smith S, Daniel P, Binnion A, Briggs L, Evans R, Ryanna K, Woltmann G, Bajammal O, Hodgson D, Saini G, Scullion J, Bolton CE, Lowrey G.

Clin Med (Lond). 2016 Aug;16(4):330-4. doi: 10.7861/clinmedicine.16-4-330.


Preoperative Opioid Use is Independently Associated With Increased Costs and Worse Outcomes After Major Abdominal Surgery.

Cron DC, Englesbe MJ, Bolton CJ, Joseph MT, Carrier KL, Moser SE, Waljee JF, Hilliard PE, Kheterpal S, Brummett CM.

Ann Surg. 2017 Apr;265(4):695-701. doi: 10.1097/SLA.0000000000001901.


Review of the Diagnostic Challenges of Lambert-Eaton Syndrome Revealed Through Three Case Reports.

Merino-Ramírez MÁ, Bolton CF.

Can J Neurol Sci. 2016 Sep;43(5):635-47. doi: 10.1017/cjn.2016.268. Epub 2016 Jul 14. Review.


Feasibility and Effectiveness of a Peer Referral Incentive Intervention to Promote Male Circumcision Uptake in Zambia.

Zanolini A, Bolton C, Lyabola LL, Phiri G, Samona A, Kaonga A, Thirumurthy H.

J Acquir Immune Defic Syndr. 2016 Aug 15;72 Suppl 4:S257-63. doi: 10.1097/QAI.0000000000000808.


Electrodiagnostic studies for neuralgic amyotrophy.

Merino-Ramírez MÁ, Bolton CF.

Muscle Nerve. 2016 Aug;54(2):341-2. doi: 10.1002/mus.25166. Epub 2016 May 27. No abstract available.


Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD.

Rabinovich RA, Miller BE, Wrobel K, Ranjit K, Williams MC, Drost E, Edwards LD, Lomas DA, Rennard SI, Agustí A, Tal-Singer R, Vestbo J, Wouters EF, John M, van Beek EJ, Murchison JT, Bolton CE, MacNee W, Huang JT; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators.

Eur Respir J. 2016 May;47(5):1365-73. doi: 10.1183/13993003.01824-2015. Epub 2016 Mar 23.


Traditional and emerging indicators of cardiovascular risk in chronic obstructive pulmonary disease.

John M, McKeever TM, Haddad MA, Hall IP, Sayers I, Cockcroft JR, Bolton CE.

Chron Respir Dis. 2016 Aug;13(3):247-55. doi: 10.1177/1479972316636995. Epub 2016 Mar 10.


Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12.

Jackson VE, Ntalla I, Sayers I, Morris R, Whincup P, Casas JP, Amuzu A, Choi M, Dale C, Kumari M, Engmann J, Kalsheker N, Chappell S, Guetta-Baranes T, McKeever TM, Palmer CN, Tavendale R, Holloway JW, Sayer AA, Dennison EM, Cooper C, Bafadhel M, Barker B, Brightling C, Bolton CE, John ME, Parker SG, Moffat MF, Wardlaw AJ, Connolly MJ, Porteous DJ, Smith BH, Padmanabhan S, Hocking L, Stirrups KE, Deloukas P, Strachan DP, Hall IP, Tobin MD, Wain LV.

Thorax. 2016 Jun;71(6):501-9. doi: 10.1136/thoraxjnl-2015-207876. Epub 2016 Feb 25.


Decrease in coccolithophore calcification and CO2 since the middle Miocene.

Bolton CT, Hernández-Sánchez MT, Fuertes MÁ, González-Lemos S, Abrevaya L, Mendez-Vicente A, Flores JA, Probert I, Giosan L, Johnson J, Stoll HM.

Nat Commun. 2016 Jan 14;7:10284. doi: 10.1038/ncomms10284.


Lung consequences in adults born prematurely.

Bolton CE, Bush A, Hurst JR, Kotecha S, McGarvey L.

Postgrad Med J. 2015 Dec;91(1082):712-8. doi: 10.1136/postgradmedj-2014-206590rep. Review.


Pulmonary arterial response to hypoxia in survivors of chronic lung disease of prematurity.

Poon CY, Watkins WJ, Evans CJ, Tsai-Goodman B, Bolton CE, Cockcroft JR, Wise RG, Kotecha S.

Arch Dis Child Fetal Neonatal Ed. 2016 Jul;101(4):F309-13. doi: 10.1136/archdischild-2015-309015. Epub 2015 Oct 21.


Matrix metalloproteinases -8 and -9 in the Airways, Blood and Urine During Exacerbations of COPD.

Cane JL, Mallia-Millanes B, Forrester DL, Knox AJ, Bolton CE, Johnson SR.

COPD. 2016;13(1):26-34. doi: 10.3109/15412555.2015.1043522. Epub 2015 Sep 29.


Role of the Timed Up and Go Test in Patients With Chronic Obstructive Pulmonary Disease.

Al Haddad MA, John M, Hussain S, Bolton CE.

J Cardiopulm Rehabil Prev. 2016 Jan-Feb;36(1):49-55. doi: 10.1097/HCR.0000000000000143.


Levels of circulating MMP-7 degraded elastin are elevated in pulmonary disorders.

Kristensen JH, Larsen L, Dasgupta B, Brodmerkel C, Curran M, Karsdal MA, Sand JM, Willumsen N, Knox AJ, Bolton CE, Johnson SR, Hägglund P, Svensson B, Leeming DJ.

Clin Biochem. 2015 Nov;48(16-17):1083-8. doi: 10.1016/j.clinbiochem.2015.07.009. Epub 2015 Jul 9.


Accelerated extracellular matrix turnover during exacerbations of COPD.

Sand JM, Knox AJ, Lange P, Sun S, Kristensen JH, Leeming DJ, Karsdal MA, Bolton CE, Johnson SR.

Respir Res. 2015 Jun 11;16:69. doi: 10.1186/s12931-015-0225-3.


Sensitivity and specificity of diagnostic ultrasound in the diagnosis of phrenic neuropathy.

Merino-Ramirez MA, Bolton CF, Boon AJ, Sorenson EJ, Strommen JA, Watson JC.

Neurology. 2015 May 26;84(21):2200. doi: 10.1212/WNL.0000000000001653. No abstract available.


Lung consequences in adults born prematurely.

Bolton CE, Bush A, Hurst JR, Kotecha S, McGarvey L.

Thorax. 2015 Jun;70(6):574-80. doi: 10.1136/thoraxjnl-2014-206590. Epub 2015 Mar 30. Review.


Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial.

John ME, Cockcroft JR, McKeever TM, Coward WR, Shale DJ, Johnson SR, Thornton JG, Harrison TW, Knox AJ, Bolton CE.

Int J Chron Obstruct Pulmon Dis. 2015 Jan 29;10:211-21. doi: 10.2147/COPD.S76061. eCollection 2015.


Selective protein kinase Cθ (PKCθ) inhibitors for the treatment of autoimmune diseases.

Curnock A, Bolton C, Chiu P, Doyle E, Fraysse D, Hesse M, Jones J, Weber P, Jimenez JM.

Biochem Soc Trans. 2014 Dec;42(6):1524-8. doi: 10.1042/BST20140167. Review.


Assessment of Risk in Chronic Airways Disease Evaluation (ARCADE): Protocol and preliminary data.

Gale NS, Albarrati AM, Munnery MM, Munnery IC, Irfan M, Bolton CE, Rambaran CN, Singer RM, Cockcroft JR, Shale DJ.

Chron Respir Dis. 2014 Nov;11(4):199-207. doi: 10.1177/1479972314546765. Epub 2014 Aug 26.


Exercise and cardiovascular benefit in subjects with COPD: the need for randomised trials.

Bolton CE, Gale NS, Cockcroft JR.

Eur Respir J. 2014 Jul;44(1):263-4. doi: 10.1183/09031936.00009714. No abstract available.


Role of IGF-I, IGF-II and IGFBP-3 in lung function of males: the Caerphilly Prospective Study.

Green CJ, Holly JM, Bolton CE, Bayer A, Ebrahim S, Gallacher J, Ben-Shlomo Y.

Int J Mol Epidemiol Genet. 2014 May 29;5(2):112-9. eCollection 2014.


Evaluating the role of inflammation in chronic airways disease: the ERICA study.

Mohan D, Gale NS, McEniery CM, Bolton CE, Cockcroft JR, MacNee W, Fuld J, Lomas DA, Calverley PM, Shale DJ, Miller BE, Wilkinson IB, Tal-Singer R, Polkey MI; ERICA Consortium.

COPD. 2014 Sep;11(5):552-9. doi: 10.3109/15412555.2014.898031. Epub 2014 May 15.


Proficiency of nerve conduction using standard methods and reference values (Cl. NPhys Trial 4).

Litchy WJ, Albers JW, Wolfe J, Bolton CF, Walsh N, Klein CJ, Zafft AJ, Russell JW, Zwirlein M, Overland CJ, Davies JL, Carter RE, Dyck PJ; CI. Nphys Trial 4 Investigators.

Muscle Nerve. 2014 Dec;50(6):900-8. doi: 10.1002/mus.24243. Epub 2014 Oct 30.


Late onset Pompe disease mimicking rigid spine syndrome.

Panosyan FB, Fitzpatrick MF, Bolton CF.

Can J Neurol Sci. 2014 Mar;41(2):286-9. No abstract available.


The British Thoracic Society guideline on pulmonary rehabilitation in adults: your opinion is noted.

Bolton CE, Blakey JD, Morgan MD; BTS Pulmonary Rehabilitation Guideline Development Group for the Standards of Care Committee for the BTS.

Thorax. 2014 Apr;69(4):388-9. doi: 10.1136/thoraxjnl-2013-204754. Epub 2014 Jan 15. No abstract available.


Children must be protected from the tobacco industry's marketing tactics.

Hopkinson N, Wallis C, Higgins B, Gaduzo S, Sherrington R, Keilty S, Stern M, Britton J, Bush A, Moxham J, Sylvester K, Griffiths V, Sutherland T, Crossingham I, Raju R, Spencer C, Safavi S, Deegan P, Seymour J, Hickman K, Hughes J, Wieboldt J, Shaheen F, Peedell C, Mackenzie N, Nicholl D, Jolley C, Crooks G, Crooks G, Dow C, Deveson P, Bintcliffe O, Gray B, Kumar S, Haney S, Docherty M, Thomas A, Chua F, Dwarakanath A, Summers G, Prowse K, Lytton S, Ong YE, Graves J, Banerjee T, English P, Leonard A, Brunet M, Chaudhry N, Ketchell RI, Cummings N, Lebus J, Sharp C, Meadows C, Harle A, Stewart T, Parry D, Templeton-Wright S, Moore-Gillon J, Stratford- Martin J, Saini S, Matusiewicz S, Merritt S, Dowson L, Satkunam K, Hodgson L, Suh ES, Durrington H, Browne E, Walters N, Steier J, Barry S, Griffiths M, Hart N, Nikolic M, Berry M, Thomas A, Miller J, McNicholl D, Marsden P, Warwick G, Barr L, Adeboyeku D, Mohd Noh MS, Griffiths P, Davies L, Quint J, Lyall R, Shribman J, Collins A, Goldman J, Bloch S, Gill A, Man W, Christopher A, Yasso R, Rajhan A, Shrikrishna D, Moore C, Absalom G, Booton R, Fowler RW, Mackinlay C, Sapey E, Lock S, Walker P, Jha A, Satia I, Bradley B, Mustfa N, Haqqee R, Thomas M, Patel A, Redington A, Pillai A, Keaney N, Fowler S, Lowe L, Brennan A, Morrison D, Murray C, Hankinson J, Dutta P, Maddocks M, Pengo M, Curtis K, Rafferty G, Hutchinson J, Whitfield R, Turner S, Breen R, Naveed SU, Goode C, Esterbrook G, Ahmed L, Walker W, Ford D, Connett G, Davidson P, Elston W, Stanton A, Morgan D, Myerson J, Maxwell D, Harrris A, Parmar S, Houghton C, Winter R, Puthucheary Z, Thomson F, Sturney S, Harvey J, Haslam PL, Patel I, Jennings D, Range S, Mallia-Milanes B, Collett A, Tate P, Russell R, Feary J, O'Driscoll R, Eaden J, Round J, Sharkey E, Montgomery M, Vaughan S, Scheele K, Lithgow A, Partridge S, Chavasse R, Restrick L, Agrawal S, Abdallah S, Lacy-Colson A, Adams N, Mitchell S, Haja Mydin H, Ward A, Denniston S, Steel M, Ghosh D, Connellan S, Rigge L, Williams R, Grove A, Anwar S, Dobson L, Hosker H, Stableforth D, Greening N, Howell T, Casswell G, Davies S, Tunnicliffe G, Mitchelmore P, Phitidis E, Robinson L, Prowse K, Bafadhel M, Robinson G, Boland A, Lipman M, Bourke S, Kaul S, Cowie C, Forrest I, Starren E, Burke H, Furness J, Bhowmik A, Everett C, Seaton D, Holmes S, Doe S, Parker S, Graham A, Paterson I, Maqsood U, Ohri C, Iles P, Kemp S, Iftikhar A, Carlin C, Fletcher T, Emerson P, Beasley V, Ramsay M, Buttery R, Mungall S, Crooks S, Ridyard J, Ross D, Guadagno A, Holden E, Coutts I, Cullen K, O'Connor S, Barker J, Sloper K, Watson J, Smith P, Anderson P, Brown L, Nyman C, Milburn H, Clive A, Serlin M, Bolton C, Fuld J, Powell H, Dayer M, Woolhouse I, Georgiadi A, Leonard H, Dodd J, Campbell I, Ruiz G, Zurek A, Paton JY, Malin A, Wood F, Hynes G, Connell D, Spencer D, Brown S, Smith D, Cooper D, O'Kane C, Hicks A, Creagh-Brown B, Lordan J, Nickol A, Primhak R, Fleming L, Powrie D, Brown J, Zoumot Z, Elkin S, Szram J, Scaffardi A, Marshall R, Macdonald I, Lightbody D, Farmer R, Wheatley I, Radnan P, Lane I, Booth A, Tilbrook S, Capstick T, Hewitt L, McHugh M, Nelson C, Wilson P, Padmanaban V, White J, Davison J, O'Callaghan U, Hodson M, Edwards J, Campbell C, Ward S, Wooler E, Ringrose E, Bridges D, Matthew Hodson, John Edwards, Colin Campbell, Simon Ward, Edwina Wooler, Elizabeth Ringrose, Diana Bridges, Rosalind Backham, Kim Randall, Tracey Mathieson, Long A, Parkes M, Clarke S, Allen B, Connelly C, Forster G, Hoadley J, Martin K, Barnham K, Khan K, Munday M, Edwards C, O'Hara D, Turner S, Pieri-Davies S, Ford K, Daniels T, Wright J, Towns R, Fern K, Butcher J, Burgin K, Winter B, Freeman D, Olive S, Gray L, Pye K, Roots D, Cox N, Davies CA, Wicker J, Hilton K, Lloyd J, MacBean V, Wood M, Kowal J, Downs J, Ryan H, Guyatt F, Nicoll D, Lyons E, Narasimhan D, Rodman A, Walmsley S, Newey A, Buxton M, Dewar M, Cooper A, Reilly J, Lloyd J, Macmillan AB, Roots D, Olley A, Voase N, Martin S, McCarvill I, Christensen A, Agate R, Heslop K, Timlett A, Hailes K, Davey C, Pawulska B, Lane A, Ioakim S, Hough A, Treharne J, Jones H, Winter-Burke A, Miller L, Connolly B, Bingham L, Fraser U, Bott J, Johnston C, Graham A, Curry D, Sumner H, Costello CA, Bartoszewicz C, Badman R, Williamson K, Taylor A, Purcell H, Barnett E, Molloy A, Crawfurd L, Collins N, Monaghan V, Mir M, Lord V, Stocks J, Edwards A, Greenhalgh T, Lenney W, McKee M, McAuley D, Majeed A, Cookson J, Baker E, Janes S, Wedzicha W, Lomas Dean D, Harrison B, Davison T, Calverley P, Wilson R, Stockley R, Ayres J, Gibson J, Simpson J, Burge S, Warner J, Lenney W, Thomson N, Davies P, Woodcock A, Woodhead M, Spiro S, Ormerod L, Bothamley G, Partridge M, Shields M, Montgomery H, Simonds A, Barnes P, Durham S, Malone S, Arabnia G, Olivier S, Gardiner K, Edwards S.

BMJ. 2013 Dec 9;347:f7358. doi: 10.1136/bmj.f7358. No abstract available.


H. Royden Jones (1936-2013).

Bolton C.

Can J Neurol Sci. 2013 Nov;40(6):893. No abstract available.


Chronic disease influences over 40 major life-changing decisions (MLCDs): a qualitative study in dermatology and general medicine.

Bhatti ZU, Finlay AY, Bolton CE, George L, Halcox JP, Jones SM, Ketchell RI, Moore RH, Salek MS.

J Eur Acad Dermatol Venereol. 2014 Oct;28(10):1344-55. doi: 10.1111/jdv.12289. Epub 2013 Oct 18.


Assessment of pulmonary artery pulse wave velocity in children: an MRI pilot study.

Poon CY, Edwards JM, Evans CJ, Harris AD, Tsai-Goodman B, Bolton CE, Cockcroft JR, Wise RG, Kotecha S.

Magn Reson Imaging. 2013 Dec;31(10):1690-4. doi: 10.1016/j.mri.2013.08.006. Epub 2013 Oct 4.


Latency can be conferred to a variety of cytokines by fusion with latency-associated peptide from TGF-β.

Mullen L, Rigby A, Sclanders M, Adams G, Mittal G, Colston J, Fatah R, Subang C, Foster J, Francis-West P, Köster M, Hauser H, Layward L, Vessillier S, Annenkov A, Al-Izki S, Pryce G, Bolton C, Baker D, Gould DJ, Chernajovsky Y.

Expert Opin Drug Deliv. 2014 Jan;11(1):5-16. doi: 10.1517/17425247.2013.839655. Epub 2013 Sep 27.


An in vivo comparison of the orientation of the transverse acetabular ligament and the acetabulum.

Griffin AR, Perriman DM, Bolton CJ, Smith PN.

J Arthroplasty. 2014 Mar;29(3):574-9. doi: 10.1016/j.arth.2013.08.002. Epub 2013 Sep 17.


Late Miocene threshold response of marine algae to carbon dioxide limitation.

Bolton CT, Stoll HM.

Nature. 2013 Aug 29;500(7464):558-62. doi: 10.1038/nature12448.


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